Drug-Resistance forecasting
This page was last updated on 2025-07-14 09:36:37 UTC
Manually curated articles on Drug-Resistance forecasting
Abstract | Title | Authors | Publication Date | Journal/ Conference | Citation count | Highest h-index | View recommendations |
---|---|---|---|---|---|---|---|
visibility_off | Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations in mismatch repair genes in methotrexate-resistant HT-29 cells | Ahreum Kim, Jong-Yeon Shin, Jeong-Sun Seo | 2020-02-27 | Experimental & Molecular Medicine, Experimental and Molecular Medicine | 5 | 49 | open_in_new |
visibility_off | Cellular adaptation to cancer therapy along a resistance continuum. | Gustavo S. França, Maayan Baron, B. King, Jozef P Bossowski, Alicia Bjornberg, Maayan Pour, A. Rao, Ayushi S. Patel, Selim Misirlioglu, Dalia Barkley, Kwan Ho Tang, Igor Dolgalev, D. A. Liberman, Gal Avital, Felicia Kuperwaser, Marta Chiodin, Douglas A. Levine, T. Papagiannakopoulos, A. Marusyk, T. Lionnet, Itai Yanai | 2024-07-10 | Nature | 46 | 43 | open_in_new |
Abstract | Title | Authors | Publication Date | Journal/ Conference | Citation count | Highest h-index | View recommendations |
Recommended articles on Drug-Resistance forecasting
Abstract | Title | Authors | Publication Date | Journal/Conference | Citation count | Highest h-index |
---|---|---|---|---|---|---|
visibility_off | Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm. | É. Oliveira, Salvatore Milite, J. Fernández-Mateos, George D. Cresswell, Erika Yara-Romero, G. Vlachogiannis, Bingjie Chen, Chela James, Lucrezia Patruno, Gianluca Ascolani, Ahmet Acar, Timon Heide, Inma Spiteri, Alex Graudenzi, G. Caravagna, Andrea Bertotti, Trevor A. Graham, Luca Magnani, Nicola Valeri, A. Sottoriva | 2025-06-11 | Cancer research | 0 | 40 |
visibility_off | A patient-derived organoid model captures fetal-like plasticity in colorectal cancer. | Liang Xiong, Ying Xu, Zhaoya Gao, Jingyi Shi, Yunfan Wang, Xiaodong Wang, Wensheng Huang, Ming Li, Longteng Wang, Jun Xu, Cheng Li, Jin Gu, Hongkui Deng, Molong Qu | 2025-07-04 | Cell research | 0 | 10 |
visibility_off | Targeting Cancer Drug-Tolerant Persister Cells in Minimal Residual Disease | Wei Zhang, Sorayut Chattrakarn, Fuhui Chen, Haobin Chai, Mariana Maranga, Jingwei Zhang | 2025-05-27 | International Journal of Drug Discovery and Pharmacology | 0 | 6 |
visibility_off | Molecular Phenotypic Plasticity Informs Possible Adaptive Change of Triple-Negative Breast Cancer Cells In Vivo | Md. Iftehimul, P. Muganda, Robert H. Newman, C. J. Rorie, Scott H. Harrison, M. T. Hossain, Misty D. Thomas, Joseph L. Graves, Dipongkor Saha | 2025-06-03 | bioRxiv | 0 | 8 |
visibility_off | A Mathematical Model of Persister Cell Plasticity and Its Impact on Adaptive Cancer Therapy | Adithya Mathews, D. Basanta | 2025-06-27 | bioRxiv | 0 | 28 |
visibility_off | Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma | A. Modrek, Ken Chandradoss, Catherine Do, R. Ezhilarasan, Theodore Sakellaropoulos, Jerome Karp, Yingwen Ding, Ze-Yan Zhang, Melanie Graciani, Giulia Cova, Jennifer E. Phillips-Cremins, Erik P. Sulman, Jane A. Skok | 2025-06-24 | bioRxiv | 0 | 22 |
visibility_off | Therapeutic targeting of mismatch repair-deficient cancers. | Paul Johannet, B. Rousseau, Carol Aghajanian, Mike Foote, Luis A. Diaz | 2025-07-10 | Nature reviews. Clinical oncology | 0 | 7 |
visibility_off | Actionable biological programs to enhance EGFR-targeted therapy response unveiled by single-cell lineage tracing in clinically relevant lung cancer models | Beatrice Gini, W. Tamaki, Johnny Yu, Dora Barbosa, Wei Wu, Yashar K Pourmoghadam, Paul Allegakoen, Donghwa Kim, S. Miglani, Sarah Elmes, V. Olivas, Hani Goodarzi, T. Bivona | 2025-05-23 | bioRxiv | 0 | 60 |
visibility_off | Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer | B. Dayanc, Sude Eris, Nazife Ege Gulfirat, Gulden Ozden-Yilmaz, E. Cakiroglu, Ozlem Silan Coskun Deniz, G. Karakülah, Serap Erkek-Ozhan, Serif Senturk | 2025-05-25 | Cell Death & Disease | 0 | 15 |
visibility_off | Drug resistance and tumor heterogeneity: cells and ensembles | Ruth Nussinov, B. R. Yavuz, Hyunbum Jang | 2025-05-31 | Biophysical Reviews | 1 | 48 |
visibility_off | Prostate cancer stem cell dynamics in the evolution of drug resistance. | Xiaoyu Zhang, Xiaoqing Zhang, Xinpei Deng, Jingna Cao, Qing Bao, Huan Wang, Dong Chen, Hailin Tang | 2025-06-04 | International journal of surgery | 1 | 1 |
visibility_off | Genome-scale knockout simulation and clustering analysis of drug-resistant breast cancer cells reveal drug sensitization targets. | JinA Lim, Hae Deok Jung, S. Park, Moonhyeon Jeon, Da Sol Kim, Ryeongeun Cho, Dohyun Han, Han Suk Ryu, Yoo-Ree Kim, Hyun Uk Kim | 2025-07-01 | Proceedings of the National Academy of Sciences of the United States of America | 0 | 9 |
visibility_off | Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family | M. B. E. Masood, Iqra Shafique, Muhammad Inam Rafique, Ayesha Iman, Ariba Abbasi, Mehak Rafiq, Uzma Habib | 2025-05-30 | PLOS One | 0 | 6 |
visibility_off | Deciphering alternative splicing patterns during cell fate transition of fast chemical reprogramming | Yunkun Lu, Kainan Lin, Yeling Ruan, Junjie Li, Huizhen Zhang, Tianyuan Pan, Qianqian Wang, Lianyu Lin, Sijie Feng | 2025-06-09 | BMC Biology | 0 | 2 |
visibility_off | Conserved cell state dynamics reveal targetable resistance patterns in ovarian high-grade serous carcinoma | A. Pirttikoski, Laura Gall-Mas, Wojciech Senkowski, David Fontaneda-Arenas, Matias Marin Falco, E. Erkan, J. Hynninen, K. Wennerberg, Anna Vähärautio | 2025-06-18 | bioRxiv | 0 | 60 |
visibility_off | Revolutionizing cancer treatment: Navigating the intricate landscape of cellular signaling networks. | Hao Zhang | 2025-05-26 | Advances in clinical and experimental medicine : official organ Wroclaw Medical University | 0 | 0 |
visibility_off | Whole Exome Sequencing and Single-Cell DNA Sequencing for Assessment of Clonal Heterogeneity and Evolution in Acute Myeloid Leukemia | Sadiksha Adhikari, S. Eldfors, Esa Pitkänen, Markus Vähä-Koskela, C. Heckman | 2025-06-01 | bioRxiv | 0 | 24 |
visibility_off | TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer | Laura Urbach, Lena Wieland, Frederike Penz, Rebecca Diya Samuel, Stefan Küffer, Lukas Klein, Christof Lenz, Ulrich Sax, Michael Ghadimi, Ramona Schulz-Heddergott, E. Hessmann, V. Ellenrieder, Nelson Dusetti, Shiv K. Singh | 2025-07-04 | Science Advances | 0 | 23 |
visibility_off | Comprehensive genomic alterations identification and potential shared neoantigens for non-small cell lung cancer immunotherapy. | Muchun Zhu, Qing Zhao Ruan, Boyue Zhang, Weiqiang Yin, Run Sheng Ruan | 2025-06-01 | Journal of Clinical Oncology | 0 | 0 |
visibility_off | Boolean network modeling: The first step toward a new understanding of breast cancer heterogeneity. | Lia Medina Montalvo, Thelma Escobedo-Tapia, Osbaldo Resendis-Antonio | 2025-06-01 | Journal of Clinical Oncology | 0 | 1 |
visibility_off | Targeting DNA helicase CMG complex and NFκB2-driven drug-resistant transcriptional axis to effectively treat KRASG12D-mutated pancreatic cancer | Jeffrey Xiao, Joshua Kim, Brandon Park, David J. Baylink, Cedric Kwon, Victoria Tran, Scott Lee, Kevin Codorniz, Laren D Tan, Pamela Lobo Moreno, Amy Schill-Depew, S. Mirshahidi, David de Semir, Diana Hanna, Kiran Naqvi, H. Cao, Chien-Shing Chen, Joanne Xiu, H. Lenz, Hamid Mirshahidi, Mark E. Reeves, Yi Xu | 2025-05-26 | Experimental Hematology & Oncology | 0 | 22 |
visibility_off | The epigenetic regulator TRIM24 controls melanoma cell dedifferentiation and resistance to treatment in melanoma | Simon Durand, Félix Boivin, Roxane M. Pommier, L. Barbollat-Boutrand, Maxime Grimont, Félix Pham, Marion Dufeu, Eric Cumunel, Raphaël Schneider, Anthony Ferrari, Anaïs Eberhardt, Stéphane Dalle, J. Caramel | 2025-05-24 | bioRxiv | 0 | 18 |
visibility_off | Pangenome-based identification of cryptic pathogenic variants in undiagnosed rare disease patients | S. S. Jang, , , , , J. Kim, J. Chae | 2025-07-11 | None | 0 | 0 |
visibility_off | Spatial transcriptomics reveal PI3K-AKT and metabolic alterations in aggressive, treatment-resistant lactotroph pituitary neuroendocrine tumors | F. Martinez-Mendoza, Sergio Andonegui-Elguera, E. Sosa-Eroza, Erick Gomez-Apo, Aurea Escobar-España, Carolina González-Torres, Javier Gaytán-Cervantes, Alam Palma-Guzman, Hugo Torres-Flores, Alberto Moscona-Nissan, S. Hinojosa-Alvarez, J. Hernández-Perez, R. Chavez-Santoscoy, G. Guinto, Gerardo Y. Guinto-Nishimura, B. López-Félix, Erick U. Zepeda-Fernandez, Erick M. Estrada-Estrada, V. Correa-Correa, P. A. González-Zavala, Marco A. Asenscio-Montiel, M. A. García-Vargas, Emmanuel Cantu-Chavez, Rocío Arreola-Rosales, Keiko Taniguchi-Ponciano, D. Marrero-Rodríguez, Moises Mercado | 2025-05-19 | Acta Neuropathologica Communications | 0 | 17 |
visibility_off | Clonal lineage tracing and parallel multiomics profiling reveal transcriptional diversification induced by ARID1A deficiency | Kenichi Miyata, Liying Yang, Yuxiao Yang, Kohei Kumegawa, R. Maruyama | 2025-05-28 | bioRxiv | 0 | 8 |
visibility_off | Single-cell and bulk transcriptome analyses reveal elevated amino acid metabolism promoting tumor-directed immune evasion in colorectal cancer | Tianyue Sun, Yan Chen, Yingsheng Chen | 2025-05-22 | Frontiers in Immunology | 0 | 1 |
visibility_off | Proneural-Mesenchymal hybrid glioblastoma cells are resistant to therapy and dependent on nuclear import. | G. Bourmeau, O. Anezo, Jeremy Raymond, A. Ballestín, C. Pichol-Thievend, J. Reveilles, Adrien Thomas, Lin Wang, Melanie Miranda, Eve Moutaux, S. Liva, V. Ribecco, L. Besse, F. Dingli, D. Loew, Céline Vallot, G. Gargiulo, V. Ravi, Kevin Joseph, G. Seano | 2025-07-08 | Neuro-oncology | 0 | 52 |
visibility_off | The SOX gene superfamily in oncogenesis: unraveling links to ncRNAs, key pathways, chemoresistance, and gene editing approaches. | Ammar Yasir Ahmed, Subasini Uthirapathy, Enwa Felix Oghenemaro, R. M, Rohit Kumawat, Yasser Fakri Mustafa, Muthena Kariem, A. J. Kadhim, Shilpa Sharma, M. R. Kumar | 2025-05-20 | Naunyn-Schmiedeberg's archives of pharmacology | 1 | 20 |
visibility_off | The Effect of X rays on the Expression of Mismatch Repair Genes and Proteins in Lynch Syndrome Associated Human Colorectal Cancer Cell Lines. | Mingzhu Sun, L. Cruz-Garcia, Danny Freestone, Kevin Monahan, C. Badie, Yannick Comoglio, Hannah Mancey, J. Moquet, Stephen Barnard | 2025-06-20 | Radiation research | 0 | 32 |
visibility_off | Clinical approaches to overcome PARP inhibitor resistance | Yutian Zou, Hanqi Zhang, Pangzhou Chen, Jiayi Tang, Siwei Yang, Christophe Nicot, Ziyun Guan, Xing Li, Hailin Tang | 2025-05-30 | Molecular Cancer | 0 | 33 |
visibility_off | Oncogenic stress response mechanisms as new therapeutic targets in cancer treatment: A review | J. Iovanna, Matias Estaras, Daniel Grasso, Martin E. Fernández Zapico, J. L. Neira, P. Santofimia-Castaño | 2025-06-13 | Medicine | 0 | 21 |
visibility_off | Abstract P5-06-09: Evaluating Functional Impacts of GATA3 Mutations in Breast Cancer Using Mesenchymal-to-Epithelial Transition Model | Aerica Nagornyuk, Mika Saotome, Nobuki Hida, Alexander Samardzic, Motoki Takaku | 2025-06-13 | Clinical Cancer Research | 0 | 2 |
visibility_off | Genome reorganization and its functional impact during breast cancer progression | K. S. Reed, Andrew J. Fritz, Haley Greenyer, Kerstin Heselmeyer-Haddad, Seth Frietze, Janet Stein, Gary S. Stein, Tom Misteli | 2025-05-17 | bioRxiv | 0 | 3 |
visibility_off | What the VAF? A guide to the interpretation of variant allele fraction, percent mosaicism, and copy number in cancer | Adam C Smith, Hubert Tsui, Sila Usta, Jose-Mario Capo-Chichi | 2025-07-08 | Molecular Cytogenetics | 0 | 16 |
visibility_off | Small intestinal neuroendocrine tumors lack early genomic drivers, acquire DNA repair defects and harbor hallmarks of low REST expression | Felix Bolduan, Niklas Müller-Bötticher, Olivia Debnath, I. Eichhorn, Yvonne Giesecke, Alexandra Wetzel, S. Sahay, Tomasz Zemojtel, Marten Jaeger, Ute Ungethuem, Christoph Roderburg, C. A. Kunze, Annika Lehmann, David Horst, Frank Tacke, Roland Eils, Bertram Wiedenmann, Michael Sigal, N. Ishaque | 2025-05-23 | Scientific Reports | 0 | 10 |
visibility_off | Pan-Cancer Exome-wide analysis of germline mutational patterns and pathways | Halima Alnaqbi, Michael Olbrich, Noora Zayed, Mira Mousa, S. Azzam, S. Tirmazy, Habiba S. Alsafar | 2025-07-01 | Scientific Reports | 0 | 26 |
visibility_off | Single-Cell Analysis of Meningiomas Reveals Mutation-Associated Tumor and Immune Cell Gene Expression Programs | Jose A. Maldonado, Bryce L. Mashimo, Anthony Z. Wang, Rupen Desai, Saad M. Khan, Ngima D Sherpa, Markus I Anzaldua-Campos, Gregory J Zipfel, Albert H. Kim, J. Dowling, Eric C. Leuthardt, Joshua W. Osbun, A. Vellimana, Michael R. Chicoine, Gavin P. Dunn, Allegra A. Petti | 2025-05-24 | bioRxiv | 0 | 25 |
visibility_off | The adaptive molecular landscape of reprogrammed telomeric sequences | Melania D’Angiolo, Benjamin P. Barré, Sakshi Khaiwal, J. Muenzner, Johan Hallin, Matteo De Chiara, Nicolò Tellini, J. Warringer, M. Ralser, Eric Gilson, Gianni Liti | 2025-06-27 | bioRxiv | 0 | 45 |
visibility_off | APOBEC3 mutagenesis drives therapy resistance in breast cancer | Avantika Gupta, Andrea M Gazzo, P. Selenica, A. Safonov, F. Pareja, E. D. da Silva, David N Brown, Hong Shao, Yingjie Zhu, Juber Patel, J. Blanco-Heredia, B. Stefanovska, Michael A. Carpenter, Yanjun Chen, Isabella Vegas, Xin Pei, D. Frosina, Achim A. Jungbluth, Marc Ladanyi, G. Curigliano, B. Weigelt, N. Riaz, Simon N. Powell, P. Razavi, R. Harris, J. Reis-Filho, Antonio Marra, S. Chandarlapaty | 2025-05-16 | Nature Genetics | 0 | 90 |
visibility_off | High-throughput mapping of spontaneous mitotic crossover and genome instability events with sci-L3-Strand-seq | Peter Chovanec, Trevor Ridgley, Yi Yin | 2025-05-24 | bioRxiv | 0 | 5 |
visibility_off | Genotype-integrated single-cell transcriptome analysis reveals the role of DDX41 pR525H in a patient with myelodysplastic neoplasms | Hirotaka Matsui, Akiko Nagamachi, Minori Koizumi, Rei Kudo, Masahiko Ajiro, H. Harada, Yuka Harada, Shigeyuki Shichino, Akihide Yoshimi | 2025-07-02 | Scientific Reports | 0 | 21 |
visibility_off | Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer | Kei Mizuno, Sheng-Yu Ku, V. B. Venkadakrishnan, Martin K. Bakht, M. Sigouros, Joanna Chan, A. Trigos, Jordan H. Driskill, J. Manohar, Abigail King, Adam G. Presser, Min Jin Kim, Alok K. Tewari, H. Long, David Quigley, T. Choueiri, Steven P. Balk, Sarah J. Hill, J. Mosquera, David Einstein, Shahneen Sandhu, M. Taplin, H. Beltran | 2025-07-01 | Nature Communications | 0 | 79 |
visibility_off | Harnessing CRISPR/Cas9 to overcome targeted therapy resistance in non‑small cell lung cancer: Advances and challenges (Review). | Jianting Du, Xian Gong, Renjie Huang, Bin Zheng, Chun Chen, Zhang Yang | 2025-09-01 | Oncology reports | 0 | 2 |
visibility_off | Opposing lineage specifiers induce a protumor hybrid identity state in lung adenocarcinoma. | Gabriela Fort, Henry Arnold, S. Camolotto, Kayla T. O'Toole, Rushmeen Tariq, Anna Waters, Katherine Gillis, Eric L. Snyder | 2025-06-12 | Genes & development | 0 | 11 |
visibility_off | Alternative Splicing in Tumorigenesis and Cancer Therapy | Huiping Chen, Jingqun Tang, Juanjuan Xiang | 2025-05-29 | Biomolecules | 1 | 4 |
visibility_off | Evolutionary Transcriptomics of Cancer Development | Roman Ivanov, D. Afonnikov, Yury Matushkin, S. Lashin | 2025-05-23 | International Journal of Molecular Sciences | 0 | 10 |
visibility_off | Loss of DNA mismatch repair genes leads to acquisition of antibiotic resistance independent of secondary mutations | David E. Bautista, Cassidy R. Whitehead, Angela M. Mitchell | 2025-06-25 | bioRxiv | 0 | 1 |
visibility_off | Extrachromosomal circular DNA drives dynamic genome plasticity: emerging roles in disease progression and clinical potential | Bin Shi, Ping Yang, Huaijin Qiao, Daojiang Yu, Shuyu Zhang | 2025-05-25 | Theranostics | 0 | 4 |
visibility_off | Monitoring the rate and variability of somatic genomic alterations using long-read sequencing | Xingyao Chen, Hagai Ligumsky, Charlie Ambrose, Denisse Sibrian, Brian Tran, Daoud Arif, Olga Castellanos, Darren Kessner, Hanyi Luo, Mukta Ubale, Abigail Coleman, Vaidhyanathan Mahaganapathy, Thomas J Jönsson, R. Basho, Jerry S H Lee, Naim Matasci, David B. Agus | 2025-06-11 | Scientific Reports | 0 | 13 |
visibility_off | Recent advances in novel targeting mechanisms for colorectal cancer. | Zhiping Li, Hailing Wang, Yan Liu, Ahequeli Gemingnuer, Yinan Wang, Xin Meng | 2025-07-11 | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico | 0 | 1 |
visibility_off | p53 in colorectal cancer: from a master player to a privileged therapy target | Sicheng Yan, Fuyuan Zhan, Yuxuan He, Yuehong Zhu, Zhihong Ma | 2025-06-19 | Journal of Translational Medicine | 0 | 1 |
visibility_off | YAP signaling promotes resistance to MEK and AKT inhibition in NF1-related MPNSTs | L. E. McGee, J. Grit, Curt J. Essenburg, Sophia Agrusa, Elizabeth A. Tovar, Lisa Turner, K. Becker, J. Zbieg, Anwesha Dey, Jennifer E. Klomp, Jeffrey A. Klomp, Marie Adams, Ian Beddows, Emily Wolfrom, Zhen Fu, A. Hirbe, Carrie R. Graveel, Matthew R. Steensma | 2025-06-26 | bioRxiv | 0 | 24 |
visibility_off | CRISPR-Based Gene Dependency Screens reveal Mechanism of BRAF Inhibitor Resistance in Anaplastic Thyroid Cancer | Shawn Noronha, Yue Liu, Gaga Geneti, Haojian Li, Xiaolin Wu, David Sun, Vaibhavi Gujar, Takashi Furusawa, Alexei Lobanov, Maggie Cam, Lipika R. Pal, N. Nair, Chi-Ping Day, E. Ruppin, Chandrayee Gosh, Jiangnan Hu, Suresh Kumar, T. Andresson, King Chan, Maura O’Neill, Raj Chari, Y. Pommier, J. Rivero, Urbain Weyemi, E. Kebebew, Myriem Boufraqech | 2025-06-27 | bioRxiv | 0 | 84 |
visibility_off | Parallel and convergent dynamics in the evolution of primary breast and lung adenocarcinomas | Robert A. Gatenby, Jamie K Teer, Kenneth Y. Tsai, Joel S. Brown | 2025-05-21 | Communications Biology | 0 | 4 |
visibility_off | CRISPR in Cancer Biology and Bovine Viral Diarrhea Therapy: Precision Genome Editing at the Frontier of Oncology and Viral Pathogenesis | Jindong Gao, Mengdi Zhang, Linjia Gao, Lei Kuang, Tuniyazi. Maimaiti, Ling Zhao, Qinghua Shang, Changmin Hu | 2025-05-19 | Bio Communications | 0 | 1 |
visibility_off | Lineage-dependent variations in single-cell antibiotic susceptibility reveal the selective inheritance of phenotypic resistance in bacteria | Wesley Stine, Tatsuya Akiyama, David S. Weiss, Minsu Kim | 2025-05-19 | Nature Communications | 0 | 6 |
visibility_off | The Rise of New Targets in Melanoma. | Xue Bai, Keith T Flaherty | 2025-06-26 | The British journal of dermatology | 0 | 2 |
visibility_off | Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art | Marija Chaushevska, Karmele Alapont-Celaya, Anne Kristine Schack, Lukasz Krych, M. C. Garrido Navas, Anastasia Krithara, Gjorgji Madjarov | 2025-07-02 | Frontiers in Genetics | 0 | 13 |
visibility_off | Identifying functional roles and pathways of shared mutations in canine solid tumors by whole-genome sequencing | YeSeul Jeon, Hyeona Bae, Seung-Wan Woo, Jaemin Kim, Dohyeon Yu | 2025-05-30 | PLOS One | 0 | 5 |
visibility_off | Integrative single-cell and spatial transcriptomics uncover ELK4-mediated mechanisms in NDUFAB1+ tumor cells driving gastric cancer progression, metabolic reprogramming, and immune evasion | Yuwei Sun, Wenyang Nie, Zhikai Xiahou, Xiaojing Wang, Wenjia Liu, Zongkai Liu, Zhiheng Lin, Zhaidong Liu | 2025-07-04 | Frontiers in Immunology | 0 | 9 |
visibility_off | Innate immunity and the NF-κB pathway control prostate stem cell plasticity, reprogramming and tumor initiation. | Chen Jiang, Yura Song, S. Rorive, Justine Allard, Elisavet Tika, Zahra Zahedi, C. Dubois, Isabelle Salmon, Alejandro Sifrim, Cédric Blanpain | 2025-06-23 | Nature cancer | 0 | 36 |
visibility_off | Bladder cancer subtypes exhibit limited plasticity across different microenvironments and in metastases | C. Bernardo, Subhayan Chattopadhyay, Natalie Andersson, P. Eriksson, Benjamin Medle, Lena Tran, Nour Al Dain Marzouka, Adam Mattsson, Aymeric Zadoroznyj, Malin Larsson, F. Liedberg, Mattias Höglund, G. Sjödahl | 2025-07-02 | Experimental Hematology & Oncology | 0 | 40 |
visibility_off | DNA repair and the contribution to chemotherapy resistance | K. Nešić, Phoebe Parker, Elizabeth M. Swisher, John J Krais | 2025-05-26 | Genome Medicine | 0 | 15 |
visibility_off | Senescence-Associated Chromatin Rewiring Promotes Inflammation and Transposable Element Activation | A. Dalgarno, Shane A. Evans, M. Kelsey, Thomas A. Nunez, Azucena Rocha, Kelly Clark, J. Sedivy, Nicola Neretti | 2025-06-17 | bioRxiv | 0 | 8 |
visibility_off | Single-cell sequencing reveals dysregulated cell type perturbations and critical mediator communication remodelling in colorectal cancer | Chengyuan Xu, Siqi Zhang, Zhouyu Zhang, Luoqiu Zhang, Bin Sun, Zicheng Yu, Hailong Liu | 2025-06-05 | Frontiers in Immunology | 0 | 2 |
visibility_off | Single-cell transcriptomics uncovers that cell-to-cell communication controls p53 activation | L. Castellano, Mark E Robinson, Aleksandra Dabrowska, Niklas Feldhahn, S. Ottaviani, Justin Stebbing | 2025-06-02 | bioRxiv | 0 | 17 |
visibility_off | Identification of hub genes and potential molecular mechanisms of tumor immune microenvironment-related radiotherapy sensitivity in locally advanced cervical cancer. | Yichen Zan, Qing Liu, Yue Yin, Chongxin Guo, Jing Xu, Junhan Gao, Guanglu Dong | 2025-06-30 | Reproductive sciences | 0 | 6 |
visibility_off | ASXL1 truncating mutations drive leukemic resistance to T cell attack | D. McCurry, Zhongqi Ge, Jaehyun Lee, Rishi Pasumarthi, Xiaohong Leng, Thomas Koehnke, O. Pasvolsky, Pranaya Raparla, Vinhkhang N. Nguyen, K. Maurer, Shuqiang Li, K. Livak, Emerie Danson, Bijal Thakkar, Elham Azizi, Robert J. Soiffer, S. Shukla, Ravi Majeti, Jerome Ritz, Catherine J. Wu, J. Molldrem, P. Bachireddy | 2025-06-12 | bioRxiv | 0 | 59 |
visibility_off | Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities | Jianfeng Ge, Shoko Hirosue, Saroor A. A. Patel, L. Wesolowski, Anna Dyas, Cissy Yong, Leticia Castillon, Sanne de Haan, J. Drost, Grant D. Stewart, Anna C Obenauf, D. Muñoz-Espín, Sakari Vanharanta | 2025-06-20 | bioRxiv | 0 | 31 |
visibility_off | Longitudinal single cell RNA-sequencing reveals evolution of micro- and macro-states in chronic myeloid leukemia | D. Frankhouser, Dandan Zhao, Yu-Hsuan Fu, Anupam Dey, Ziang Chen, Jihyun Irizarry, Jennifer Rangel Ambriz, S. Branciamore, Denis O’Meally, Lucy Ghoda, Jeffery M. Trent, Stephen J Forman, Adam L. Maclean, Ya-Huei Kuo, Bin Zhang, Russell C. Rockne, Guido Marcucci | 2025-05-17 | bioRxiv | 0 | 19 |
visibility_off | PCNA in Pan-Cancer: A Prognostic Biomarker Unveiled Through a Data-Driven, Multidimensional Analysis of Transcriptomics, Immunity, and Functional Profiling | Depanshi Pandit, Ravindranath Bilachi Sanganabasappa, Amardeep Dhillon, Sanjiban Chakrabarty | 2025-06-26 | ACS Omega | 0 | 21 |
visibility_off | Characterization of Somatic Mutations in Human tRNA Genes Reveals Tumor-Specific Mutational Loads, and the Generation of tRNA Variants that Alter the Genetic Code | Marina Murillo-Recio, Marina Salvadores, Adrián Gabriel Torres, Lina Tsapanou, Aina Vaquer Picó, F. Supek, L. R. de Pouplana | 2025-06-09 | bioRxiv | 0 | 46 |
visibility_off | Reprogramming of Cellular Plasticity via ETS and MYC Core-regulatory Circuits During Response to MAPK Inhibition in BRAF-mutant Colorectal Cancer | H. Lee, Zhao Zheng, Alexey Sorokin, Chi Wut Wong, Stefania Napolitano, S. Chowdhury, Preeti Kanikarla, A. Singh, Veena Kochat, Christopher Bristow, Sanjana Srinivasan, Mike Peoples, Emre Arslan, J. Alshenaifi, O. Villarreal, V. Morris, J. P. Shen, F. Meric-Bernstam, Abhinav K. Jain, Natalie W Fowlkes, Amanda Anderson, D. Menter, A. Saw, Kunal Rai, S. Kopetz | 2025-06-20 | bioRxiv | 0 | 47 |
visibility_off | A Review Article: Evaluation of the Frequency of Genetic Mutations in Leukemia. | A. Hamadi | 2025-06-01 | Discovery medicine | 0 | 6 |
visibility_off | From cytogenetics to proteogenomics: new horizons in the study of aneuploidies | K. Zadesenets, N. B. Rubtsov | 2025-06-01 | Vavilov Journal of Genetics and Breeding | 0 | 12 |
visibility_off | The effect of prolonged G-quadruplex stabilization on the functions of human cells | Nargis Karatayeva, Lili Hegedűs, Arindam Bhattacharjee, Eszter Németh, Ádám Póti, Lorinc Pongor, Gábor Juhász, David Szuts, Peter Burkovics | 2025-06-04 | Scientific Reports | 0 | 12 |
visibility_off | Unmasking Human T Cell Receptor Germline Diversity: 335 Novel Alleles Identified in 47 Pangenome Reference Individuals Using the gAIRR Suite | Yu-Hsuan Yang, C. Yao, Mao-Jan Lin, Kuan-Ta Huang, Yu-Hui Lin, I-Hsuan Chiu, Sheng-Kai Lai, Chih-Yeh Chen, Ya-Chien Yang, Chia-Lang Hsu, Jacob Shu-Jui Hsu, Chien-Yu Chen, Pei-Lung Chen | 2025-05-25 | bioRxiv | 0 | 9 |
visibility_off | Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma | Olivia G. Waltner, April A. Apfelbaum, Emma D. Wrenn, Shruti S Bhise, Sami B. Kanaan, R. Gladden, Mark A. Mendoza, R. Volden, Z. Kronenberg, Anand G. Patel, Michael A Dyer, J. Sarthy, Elizabeth R. Lawlor, Scott N. Furlan | 2025-06-24 | bioRxiv | 0 | 10 |
visibility_off | Distinct evolutionary patterns of tumour-immune escape and elimination determined by extracellular matrix architectures. | Yijia Fan, Jason T. George | 2025-07-01 | Journal of the Royal Society, Interface | 0 | 2 |
visibility_off | Amplification of select autonomous HERV loci and surrounding host gene transcription in monocytes from patients with post-acute sequelae of COVID-19 | Hyunmin Koo, Casey D. Morrow | 2025-06-26 | Frontiers in Immunology | 0 | 15 |
visibility_off | Changes in mitochondrial thymidine metabolism and mtDNA copy number during induced pluripotency | Hyun Kyu Kim, Yena Song, Minji Kye, Byeongho Yu, Hyungkyu Choi, Sung-Hwan Moon, M. Lee | 2025-06-01 | Experimental & Molecular Medicine | 0 | 8 |
visibility_off | Quantitative analysis of genetic interactions in human cells from genome-wide CRISPR-Cas9 screens | Maximilian Billmann, M. Costanzo, Mahfuzur Rahman, Katherine Chan, Amy Hin Yan Tong, Henry N. Ward, Arshia Z. Hassan, Xiang Zhang, , Thomas Rohde, A. H. Shaw, Catherine Ross, Jolanda van Leeuwen, Michael Aregger, Keith A. Lawson, Barbara Mair, P. Mero, Matej Ušaj, Brenda J. Andrews, Charles Boone, Jason Moffat, Chad L. Myers | 2025-06-30 | bioRxiv | 0 | 52 |
visibility_off | High Throughput Screening Identifies Small Molecules that Synergize with MRTX1133 Against Acquired Resistant KRAS G12D Mutated CRC | Natalie Thielen, Ning Wei, Emiko Nagai, Edward Chu, S. Kitamura, Chaoyuan Kuang | 2025-07-02 | bioRxiv | 0 | 14 |
visibility_off | Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer | Juliana Rodriguez-Salamanca, Mariana Angulo-Aguado, Sarah Orjuela-Amarillo, Catalina Duque, Diana Carolina Sierra-Díaz, Nora Constanza Contreras Bravo, Carlos Figueroa, Carlos Restrepo, Andrés López-Cortés, Rodrigo Cabrera, Adrien Morel, D. Fonseca-Mendoza | 2025-05-19 | Frontiers in Oncology | 0 | 8 |
visibility_off | Integrating single-cell with transcriptome-proteome Mendelian randomization reveals colorectal cancer targets | Song Wang, Xin Yao, Shenshen Li, Shanshan Wang, Xuyu Huang, Jing Zhou, Xiao Li, Jieying Wen, Weixuan Lan, Yunsi Huang, Hao Li, Yunlong Sun, Xiaoqian Zhao, Qiaoling Chen, Xuedong Han, Ziming Zhu, Xinyue Zhang, Tao Zhang | 2025-05-17 | Discover Oncology | 0 | 1 |
visibility_off | Whole-genome sequencing of biliary tract cancer: Uncovering the genomic origins of evolutionary trajectories. | Felix Beaudry, Nicholas Light, Duhan Yendi, A. Zorigtbaatar, Maggie Hildebrand, A. Dodd, Roxana Bucur, Julie M. Wilson, Enrique Sanz Garcia, Xin Wang, Erica S. Tsang, G. O’Kane, S. Gallinger, Arndt Vogel, Jennifer J Knox, F. Notta, G. Sapisochin, Robert C Grant | 2025-06-01 | Journal of Clinical Oncology | 0 | 39 |
visibility_off | N6-methyladenosine-modified GPX2 impacts cancer cell stemness and TKI resistance through regulating of redox metabolism | Xu Yang, Long Yu, Miaomiao Shao, Huiling Yang, Kangwei Qi, Gaofei He, Lanxin Wang, Di Kong, Jianxin Gu, Xiaolin Xu, Lanxin Wang | 2025-06-18 | Cell Death & Disease | 0 | 3 |
visibility_off | Loss of chromosome Y shapes the immune cell fate with aging in men | A. A. Z. Dawoud, L. Green, O. Rackham | 2025-06-02 | None | 0 | 0 |
visibility_off | Dysfunction of core clock genes regulates malignant phenotype and gemcitabine sensitivity of cholangiocarcinoma cells. | Yin Li, Aimin Zheng, Yangang Cui, Tianbao Liu | 2025-06-17 | Anti-cancer drugs | 0 | 2 |
visibility_off | Integration of chromosome conformation and gene expression networks reveals regulatory mechanisms in triple negative breast cancer | Helena Reyes-Gopar, Keila Adonai Pérez-Fuentes, M. Bendall, Enrique Hernández-Lemus | 2025-07-04 | Frontiers in Cell and Developmental Biology | 0 | 19 |
visibility_off | The plk1 Gene Regulatory Network Modeling Identifies Three Circuits for plk1-mediated Genomic Instability Leading to Neoplastic Transformation | Jeison F. Suescum-Holguín, Diana Carolina Clavijo-Buriticá, Edward Fabian Carrillo-Borda, M. Quimbaya | 2025-05-01 | Life | 0 | 10 |
visibility_off | TET3 facilitates bladder cancer progression through targeted modulation of stemness pathways. | Zhiren Cai, Yanqi Xie, Luyao Li, Yuhang Zheng, Xianghui Zhou, Guanghua Zhou, Ganping Wang, Xin Zeng | 2025-06-26 | Medical oncology | 0 | 2 |
visibility_off | X-chromosome upregulation operates on a gene-by-gene basis at RNA and protein levels | Ryan N. Allsop, Jeffrey Boeren, Beatrice F. Tan, Sarra Merzouk, Suresh Poovanthingal, W. V. van Ijcken, Jeroen Demmers, Hegias Mira Bontenbal, C. Gontan, J. Gribnau, V. Pasque | 2025-06-27 | bioRxiv | 0 | 66 |
visibility_off | Targeting CDKs in cancer therapy: advances in PROTACs and molecular glues | Hany E. Marei, Khaled Bedair, Anwarul Hasan, Layla Al-mansoori, Alice Gaiba, Andrea Morrione, C. Cenciarelli, Antonio Giordano | 2025-06-28 | NPJ Precision Oncology | 0 | 30 |
visibility_off | Prognostic and immunological landscape of DDX17 in pan-cancer analysis: a comprehensive study | Yu Lei, Xin He, Peng Chen, Yiping Qin, Bin Ge, Yan Liu, Pu Li, Xing Wei | 2025-06-17 | Discover Oncology | 0 | 2 |
visibility_off | Genetics of growth rate in induced pluripotent stem cells | Brian N. Lee, Henry J. Taylor, Filippo Cipriani, Narisu Narisu, Catherine C. Robertson, A. Swift, Neelam Sinha, Tingfen Yan, L. Bonnycastle, Nathan Dale, Annie Butt, Hemant Parsaud, Stefan Semrau, Joshua W Knowles, Ivan Carcamo-Orive, Agnieszka D’Antonio-Chronowska, K. Frazer, Leslie G. Biesecker, S. Noggle, Michael R. Erdos, Dan Paull, Francis S. Collins, D. L. Taylor | 2025-07-03 | bioRxiv | 0 | 74 |
visibility_off | Novel Avenues for the Detection of Cancer-Associated Viral Genome Integrations Using Long-Read Sequencing Technologies | Larissa-Anna Bergmann, Alicja Pacholewska, Michal R. Schweiger | 2025-05-22 | Cancers | 0 | 13 |
visibility_off | A Super-Enhancer-Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration-Resistant Prostate Cancer. | Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi | 2025-06-05 | Advanced science | 0 | 21 |
visibility_off | Epigenetic Therapeutics: Reprogramming Triple-Negative Breast Cancer into Responsive Subtypes. | Wafaa S. Ramadan, Aya Mudhafar Al-Azawi, L. Lozon, Rawan R. Kawaf, Ragheb Alsheikh Zein, Yahia El-Gharib, Raafat El-Awady | 2025-07-01 | Endocrine-related cancer | 0 | 3 |
visibility_off | Molecular-genetic characteristics of soft tissue sarcomas associated with the development of chemotherapy resistance. | A. Tararykova, T. Fetisov, P. Shtompel, S. Khazanova, E. Trapeznikova, Maxim Menyailo, A. Ikonnikov, Elena E Kopantseva, A. Korobeynikova, B. Bokhyan, M. Yakubovskaya, K. Kirsanov | 2025-06-01 | Journal of Clinical Oncology | 0 | 15 |
visibility_off | Abstract P3-02-26: Sex-biased cancer cells induce endocrine therapy resistance and immune suppression in male breast cancer | Zhishuang Gao, Zehao Wang, Yue Zhou, Xiaoting Chen, J. Xue, Jiong Wu | 2025-06-13 | Clinical Cancer Research | 0 | 19 |
visibility_off | A Network-Driven Framework for Drug Response Precision Prediction of Acute Myeloid Leukemia. | Yinyin Wang, Rui Liu, Yinnan Zhang, Xiang Luo, Chengzhuang Yu, Shentong Fang, Ninghua Tan, Jing Tang | 2025-07-11 | Advanced science | 0 | 5 |
visibility_off | Divergent Evolution of Malignant Subclones Maintains a Balance Between Induced Aggressiveness and Intrinsic Drug Resistance in T Cell Cancer. | T. B. Buus, C. K. Vadivel, Maria Gluud, Martin R J Namini, Ziao Zeng, S. Hedebo, Menghong Yin, A. Willerslev-Olsen, Emil M H Pallesen, Lang Yan, E. Blümel, E. U. Ewing, S. Ahmad, Lara P Sorrosal, Carsten Geisler, C. Bonefeld, A. Woetmann, M. Andersen, T. Mustelin, Claus Johansen, Marion Wobser, M. Kamstrup, E. Guenova, Jürgen C. Becker, S. Koralov, R. Bech, N. Ødum | 2025-06-16 | Cancer discovery | 0 | 45 |
visibility_off | Multimodal profiling unveils a reversible basal-like breast cancer cell state resistant to AKT inhibition | Colin D. H. Ratcliffe, Hugh Sparks, G. L. Boezio, Yuriy Alexandrov, Robert P. Jenkins, A. Le Marois, Pablo Soro-Barrio, Rebecca Lee, S. Strohbuecker, Sudeep Joshi, James K. Ellis, Anne-Marie Fortier, Nils Gustafsson, Ana C. Cunha, Morag Park, J. Macrae, A. Serio, J. Briscoe, Andy Riddell, S. Barry, Chris Dunsby, E. Sahai | 2025-06-07 | bioRxiv | 0 | 12 |
visibility_off | Mechanisms of efficacy of endonuclease inhibition in neuroblastoma. | Carla Sampaio, Eric Wu, Madison Cinelli, Erica Steen, Andrew Shiau, Richard Kolodner, Jean Yin Jen Wang, Peter E. Zage | 2025-06-01 | Journal of Clinical Oncology | 0 | 2 |
visibility_off | An in-frame deletion mutation in MLH1 drives Lynch syndrome-associated colorectal cancer | Xiaojuan Lin, Ce Bian, Dongni Liang, Lin Li, Qingqing Tang, Qingli Li | 2025-07-11 | BMC Cancer | 0 | 1 |
visibility_off | Epigenetic Remodeling of Regulatory Regions by Indicaxanthin Suggests a Shift in Cell Identity Programs in Colorectal Cancer Cells | M. Ragusa, C. Gentile, Aldo Nicosia, Salvatore Costa, Sara Volpes, Laura Greco, F. Naselli, Fabio Caradonna | 2025-06-24 | International Journal of Molecular Sciences | 0 | 12 |
visibility_off | Multi-selective RAS(ON) Inhibition Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 and BCL2 Inhibitors in Acute Myeloid Leukemia | Bogdan Popescu, Matthew F. Jones, Madison Piao, Elaine Tran, Andrew Koh, Isabelle Lomeli, C. Peretz, Natalia Murad, Sydney Abelson, Carolina E. Morales, Jose M. Rivera, Y. Pikman, Michael L. Cheng, Aaron C. Logan, Elliot Stieglitz, Catherine C. Smith | 2025-06-14 | bioRxiv | 0 | 20 |
visibility_off | Post-translational modifications in DNA damage repair: mechanisms underlying temozolomide resistance in glioblastoma. | Yike Chen, Kaikai Ding, Shuyu Zheng, Songting Gao, Xiaohui Xu, Haijian Wu, Fengqi Zhou, Yongjie Wang, Jinfang Xu, Chun Wang, C. Ling, Jing Xu, Lin Wang, Qun Wu, G. Giamas, Gao Chen, Jianmin Zhang, Chenggang Yi, Jianxiong Ji | 2025-05-26 | Oncogene | 0 | 32 |
visibility_off | Dysregulation of DNA damage repair in lung cancer driven by MTAP loss: Mechanistic insights and target discovery. | Bo Jiang, W. Liao, Xin Wang, Hongliang Hui, Yan-Gui Lin, Linjie Qiu, Dan Li, Min Luo, Haoran Miao, Fan Qiu, Yiqian Zhang | 2025-06-01 | Journal of Clinical Oncology | 0 | 8 |
visibility_off | Discovery of Drugs Targeting Mutant p53 and Progress in Nano-Enabled Therapeutic Strategy for p53-Mutated Cancers | Na Zhang, Zhiyuan Jing, Jie Song, Qiyue Liang, Yuxue Xu, Zhaowei Xu, Longping Wen, Pengfei Wei | 2025-05-26 | Biomolecules | 0 | 3 |
visibility_off | Allelic expression patterns of imprinted and non-imprinted genes in cancer cell lines from multiple histologies | Julia Krushkal, Travis L. Jensen, George Wright, Yingdong Zhao | 2025-05-25 | Clinical Epigenetics | 0 | 2 |
visibility_off | Functional Characterization of LTR12C as Regulators of Germ-Cell-Associated TA-p63 in U87-MG and T98-G In Vitro Models | Lucia Meola, Sohum Rajesh Shetty, A. Peschiaroli, Claudio Sette, Camilla Bernardini | 2025-06-01 | Cells | 0 | 29 |
visibility_off | Structure, Function and Clinical Significance of P53 Protein: A Review Article | Farah mumtaz, Hadeel Nasser, Ruqaya Yahya Abd AL-Shaheed, Ali A. Al-fahham | 2025-05-28 | International Journal of Health & Medical Research | 0 | 4 |
visibility_off | Heterogeneity of Genetic Sequence within Quasi-species of Influenza Virus Revealed by Single-Molecule Sequencing | Kenji Tamao, Hiroyuki Noji, K. Tabata | 2025-06-19 | bioRxiv | 0 | 24 |
visibility_off | Transcriptional Biomarkers in the Diagnosis of Genetic Disorders: Opportunities, Challenges, and Prospects for Application. | Lidia N. Nefedova, Tatiana N. Krasnova | 2025-06-01 | Biochemistry. Biokhimiia | 0 | 1 |
visibility_off | Cell-type-specific patterns and consequences of somatic mutation in development and aging brain | Andrea J. Kriz, Shulin Mao, Diane D. Shao, Daniel A. Snellings, Rebecca E. Andersen, Guanlan Dong, Chanthia C. Ma, Hayley E. Cline, A. Huang, Eunjung Lee, Christopher A. Walsh | 2025-05-31 | bioRxiv | 0 | 3 |
visibility_off | LaGrACE: estimating gene program dysregulation with latent regulatory network. | Minxue Jia, Haiyi Mao, Mengli Zhou, Yu-Chih Chen, P.V. Benos | 2025-06-30 | Molecular systems biology | 0 | 3 |
visibility_off | Gene and pathway analysis of genome-wide genetic associations of bladder cancer | Mingjun Shi, Xiangyu Meng, Xuan Xu, Qiaoli Wang | 2025-06-05 | Current Urology | 0 | 1 |
visibility_off | Abstract P2-02-08: Chromosome 8q gain-related transcription factor MYBL1 is a critical regulator in triple-negative breast cancer | Akihiro Fujimoto, K. Ikeda, Keiichi Kinowaki, H. Kawabata, Akihiko Osaki, Satoshi Inoue, K. Horie | 2025-06-13 | Clinical Cancer Research | 0 | 46 |
visibility_off | Breaking Boundaries in Cancer Therapy: Harnessing Chromothripsis- Induced Mutations for Targeted BCL2 Protein Destabilization. | Sergey Shityakov, Michael Nosonovsky, Ekaterina V. Skorb, Viacheslav Kravtsov | 2025-06-02 | Current drug discovery technologies | 0 | 3 |
visibility_off | Double strand breaks drive toxicity in Huntington’s disease mice with or without somatic expansion | Aris A. Polyzos, Ana Cheong, Jung Hyun Yoo, Lana Blagec, Zachary D. Nagel, Cynthia T McMurray | 2025-05-28 | bioRxiv | 0 | 5 |
visibility_off | A transient mutational burst occurs during yeast colony development. | Nicolas Agier, Nina Vittorelli, Louis Ollivier, Frédéric Chaux, Alexandre Gillet-Markowska, Samuel O'Donnell, Fanny Pouyet, G. Fischer, Stéphane Delmas | 2025-06-09 | Molecular systems biology | 0 | 20 |
visibility_off | DIFFERENTIAL ROLES OF RAD18 IN REPRESSING CARCINOGEN- AND ONCOGENE-DRIVEN MUTAGENESIS IN VIVO | J. R. Anand, Bethany Wagner, Jitong Lou, Qisheng Gu, Yang Yang, Gaith Droby, Di Wu, Akankshya Jena, Jialiu Xie, Yuri Fedoriw, Bernard E Weissman, Scott E. Williams, Cyrus Vaziri | 2025-07-04 | bioRxiv | 0 | 11 |
visibility_off | Homologous recombination-DNA damage response defects increase TMB and neoantigen load, but not effector T cell density and clonal diversity in pancreatic cancer | Mengyue Lei, Jessica Gai, T. McPhaul, Huijuan Luo, Penghui Lin, Dongbin Liu, Michael Pishvaian, Nicholas J Roberts, Kui Wu, Jin He, Lei Zheng | 2025-06-18 | Experimental Hematology & Oncology | 0 | 5 |
visibility_off | Use of CRISPR-KO screening to identify novel genes and pathways potentially contributing to cisplatin resistance in testicular germ cell tumors. | Laura Matouskova, Kristyna Soffrova, V. Bakardjieva-Mihaylova, J. Stuchlý, L. Boublikova, Karolina Skvarova | 2025-06-01 | Journal of Clinical Oncology | 0 | 20 |
visibility_off | Abstract GS2-11: APOBEC3 mutagenesis induces resistance-promoting genomic alterations in breast cancer | Avantika Gupta, Andrea M Gazzo, P. Selenica, A. Safonov, F. Pareja, E. D. da Silva, David N Brown, Yingjie Zhu, Juber Patel, J. Blanco-Heredia, B. Stefanovska, Michael A. Carpenter, Xin Pei, D. Frosina, Achim A. Jungbluth, Marc Ladanyi, Giuseppe Curigliano, B. Weigelt, N. Riaz, Simon Powell, P. Razavi, R. Harris, J. Reis-Filho, Antonio Marra, S. Chandarlapaty | 2025-06-13 | Clinical Cancer Research | 0 | 90 |
visibility_off | Metabolite correlation networks reveal complex phenotypes of adaptation-driving mutations | Sharon Samuel, Weronika Jasinska, Ezra Sternlicht, Matvey Nikelshparg, D. Kleiner, S. Pilosof, Shimon Bershtein | 2025-06-20 | bioRxiv | 0 | 18 |
visibility_off | Cell-Derived Epigenomic Markers of Chronic Stress Distinguish Breast Cancer Phenotypes | Amrita Acharya, Anthony S. Zannas | 2025-06-01 | The Yale Journal of Biology and Medicine | 0 | 3 |
visibility_off | LSINCT5: a pivotal oncogenic long non-coding RNA in cancers. | Sharanya K Sritharan, Amar Harris Arifin, S. Salvamani, R. Koh, B. Gunasekaran | 2025-06-02 | Functional & integrative genomics | 0 | 21 |
visibility_off | Abstract PS13-04: DREAM complex assembly and stable cell cycle control underlies long-term clinical response to CDK4/6 inhibition | Rei Kudo, A. Safonov, E. Moiso, Catherine Jones, Hong Shao, Sharanya Nag, Selma Yeni Yildirim, E. D. da Silva, Qing Li, Marie Will, A. Fushimi, H. Nakshatri, Andrew Koff, B. Weigelt, Qamar J Khan, P. Razavi, S. Chandarlapaty | 2025-06-13 | Clinical Cancer Research | 0 | 90 |
visibility_off | Identification of novel genetic mutations for the treatment prognostication of canine lymphoma | Josephine Tsang, Qi-Jing Yap, Sheena Kapoor, Jerry Cromarty, Sushmita Sen, Minji Kim, George Courcoubetis, Suhyeon Cho, Deanna Swartzfager, Stanley Park, Sungwon Lim, Ilona Holcomb, Jamin Koo | 2025-06-12 | NPJ Precision Oncology | 0 | 6 |
visibility_off | MCT1-mediated histone lactylation modulates lung cancer cell sensitivity to T-cell–mediated killing by influencing mitochondrial dysfunction. | Q. Xue, W. Peng, Qiong Zhou | 2025-06-01 | Journal of Clinical Oncology | 0 | 10 |
visibility_off | Cx43 enhances response to BRAF/MEK inhibitors by reducing DNA repair capacity | A. Varela-Vázquez, A. Guitián-Caamaño, P. Carpintero-Fernández, Alexander Carneiro-Figueira, Vanesa Álvarez, M. Varela-Eirín, Teresa Calleja-Chucla, S. B. Bravo-López, Anxo Vidal, Juan Sendón-Lago, Marina Rodríguez-Candela Mateos, José R Caeiro, Victoria Sanz-Moreno, Trond Aasen, Miguel G. Blanco, Guadalupe Sabio, María Quindós, Carmen Rivas, David Santamaría, Carlos Fernandez-Lozano, E. Fonseca, Pablo Huertas, Berta Sánchez-Laorden, Constance Alabert, M. Mayán | 2025-07-04 | Nature Communications | 0 | 25 |
visibility_off | Single-cell transcriptional dissection illuminates an evolution of immunosuppressive microenvironment during pancreatic ductal adenocarcinoma metastasis | Xiaowei Liu, Jinen Song, Meiling Yuan, Fengli Zuo, Huihui Li, Leyi Tang, Xinmin Wang, Xueyan Wang, Qian Xiao, Li Li, Xinyu Liu, Zhankun Yang, Jian-Lin Wu, Jing Jing, Xuelei Ma, Hubing Shi | 2025-06-09 | Signal Transduction and Targeted Therapy | 0 | 9 |
visibility_off | Epithelial state-transitions permit inflammation-induced tumorigenesis | E. Jarman, Anabel Martinez Lyons, Yuelin Yao, Aleksandra Rozyczko, S. Waddell, Andreea Gradinaru, Paula Olaizola, Kyle Davies, Rachel V. Guest, Stephanie Röessler, Timothy J. Kendall, Owen J Sansom, A. Khamseh, Luke Boulter | 2025-06-27 | bioRxiv | 0 | 9 |
visibility_off | The TP53 tumor suppressor gene: From molecular biology to clinical investigations | Panagotis Baliakas, Thierry Soussi | 2025-06-16 | Journal of Internal Medicine | 0 | 6 |
visibility_off | REpair of heterozygous Mutations independent of Exogenous Donor template with high efficiency (REMEDY) using allele specific CRISPR targeting and HDR enhancers | Y. Sezgin, Genesis Snyder, Noushin Saljoughian, Colin Maguire, Ebru Erzurumluoglu Gokalp, Devi Jaganathan, Eleonora S D'Ambrosio, B. Ozes, Gregory Wheeler, Ben Kelly, Mark E. Hester, Zarife Sahenk, S. Vaidyanathan, A. Rashnonejad, Jerry Mendell, Nizar Y. Saad, Roshini S. Abraham, Juhi Bagaitkar, Susan D. Reynolds, Allison Bradbury, M. N. Kararoudi | 2025-05-30 | bioRxiv | 0 | 9 |
visibility_off | Oncogenic lncRNA transgene transcription modulates epigenetic memory at a naïve chromosomal locus | Sweta Sikder, Songjoon Baek, Yamini Dalal, Ganesan Arunkumar | 2025-05-19 | bioRxiv | 0 | 4 |
visibility_off | Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG | I. Mersich, Sunny Congrove, Matthew Horchar, Roman Caceres, Ranjithmenon Muraleedharan, Janki M Desai, Pankaj B Desai, Larry Sallans, J. Reisz, Abby Grier, Matthew R. Hass, Omer Donmez, Cailing Yin, M. Weirauch, Leah C. Kottyan, Charles B. Stevenson, Claire X. Sun, P. D. de Blank, N. Pillay-Smiley, T. Hummel, N. Elumalai, Ali Tavassoli, Ron Firestein, T. Phoenix, A. D'alessandro, Biplab Dasgupta | 2025-05-24 | bioRxiv | 0 | 60 |
visibility_off | Abstract 3806: Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML | Andy G. X. Zeng, Ilaria Iacobucci, Sayyam Shah, Amanda Mitchell, Gordon Wong, Suraj Bansal, David Chen, Qingsong Gao, Hyerin Kim, James A Kennedy, Andrea Arruda, Mark D. Minden, Torsten Haferlach, C. Mullighan, J. Dick | 2025-05-22 | Cancer Research | 0 | 104 |
visibility_off | Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes. | Yu Yuan, Ziyu Jiang, Yuxin Zeng, Jiawen Tang, Jiang Luo, Conghua Xie, Yan Gong | 2025-05-23 | Journal of visualized experiments : JoVE | 0 | 4 |
visibility_off | Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies | Yonghyo Kim, V. Doma, Uğur Çakır, M. Kuras, L. Betancourt, I. Pla, Aniel Sanchez, Y. Sugihara, R. Appelqvist, Henriett Oskolás, Boram Lee, Jéssica Guedes, G. Monnerat, G. Carneiro, Fábio Nogueira, G. Domont, Johan Malm, Bo Baldetorp, E. Wieslander, I. Németh, A. M. Szasz, R. Hong, Krzysztof Pawłowski, M. Rezeli, H. Kwon, József Timár, David Fenyö, S. Kárpáti, Gyorgy Marko-Varga, Jeovanis Gil | 2025-06-23 | Cancer | 1 | 27 |
visibility_off | Minimal activation of the p53 DNA damage response by a modular cytosine base editor enables effective multiplexed gene knockout in induced pluripotent stem cells | R. Blassberg, Olga Mielczarek, J. Stombaugh, H. Okkenhaug, Alice Abreu Torres, Paul Russell, John Lambourne, Immacolata Porreca | 2025-06-07 | bioRxiv | 0 | 10 |
visibility_off | Multi-omics analyses of the complex interplay between genetic variants, DNA methylation, and gene expression in COVID-19. | Guanjie Chen, Lisa DeRoo, Gabriel Goodney, A. Doumatey, Jie Zhou, A. Adeyemo, C. Rotimi, Amadou Gaye | 2025-07-01 | American journal of physiology. Heart and circulatory physiology | 0 | 88 |
visibility_off | Decoding the Transcriptional Complexity of the Human BRCA2 DNA Repair Gene Using Hybrid-seq. | P. Adamopoulos, Michaela A. Boti, Konstantina Athanasopoulou, P. Tsiakanikas, Glykeria N. Daneva, Andreas Scorilas | 2025-07-10 | Biochemical genetics | 0 | 16 |
visibility_off | ITX-0121: A therapeutic strategy for transcription-coupled repair-deficient cancers. | M. Kelner, Raymond T. Suhandynata, Venkata R. Kotamraju | 2025-06-01 | Journal of Clinical Oncology | 0 | 3 |
visibility_off | Uncovering minimal pathways in melanoma initiation | Hui Xiao, Jessica Shiu, Chi-Fen Chen, Jie Wu, Peijie Zhou, Sahil S. Telang, Rolando Ruiz-Vega, Robert A Edwards, Qing Nie, A. D. Lander, Anand K. Ganesan | 2025-06-26 | Nature Communications | 0 | 10 |
visibility_off | KSHV reprograms host RNA splicing via FAM50A to activate STAT3 and drive oncogenic cellular transformation | Shenyu Sun, Ling Ding, Karla Paniagua, Xian Wang, Yufei Huang, Mario A. Flores, Shou‐Jiang Gao | 2025-06-12 | mBio | 0 | 5 |
visibility_off | The role of DNA methylation and demethylation in bladder cancer: a focus on therapeutic strategies | Wiktoria Strasenburg, Jędrzej Borowczak, Daria Piątkowska, J. Jóźwicki, Dariusz Grzanka | 2025-06-26 | Frontiers in Oncology | 0 | 6 |
visibility_off | Unraveling the genetic blueprint of doxorubicin-induced cardiotoxicity through systems genetics approaches | Buyan-Ochir Orgil, A. Bajpai, Neely R. Alberson, Morgan Lander, Batsaikhan Enkhzul, Hugo R. Martinez, Jeffrey A Towbin, Lu Lu, E. Purevjav | 2025-06-03 | Cardio-oncology | 0 | 19 |
visibility_off | Single-cell transcriptomic analysis of canine insulinoma reveals distinct sub-populations of insulin-expressing cancer cells | M. Wallace, M. E. Herrtage, R. Gostelow, L. Owen, L. Rutherford, K. Hughes, A. Denyer, B. Catchpole, C. A. O’Callaghan, L. Davison | 2025-05-26 | Veterinary Oncology (London, England) | 0 | 9 |
visibility_off | Non-genetic mechanisms in cancer evolution: senescence, unicellularization, and cycles of stemness recovery | V. Niculescu | 2025-06-25 | Academia Molecular Biology and Genomics | 0 | 8 |
visibility_off | A DNA alteration and methylation co-detection method for clinical purpose | Jiyan Yu, Chunhe Yang, Xintao Zhu, Zhankun Wang, Boping Xu, Ye Cai, Jingbo Zhao, Ruijian Guo, Wuzhou Yuan, Jianqing Wang, Bohao Dong, Frank Ron Zheng, Shuang Yang | 2025-06-04 | EMBO Molecular Medicine | 0 | 0 |
visibility_off | Regulatory Genetic Networks by microRNAs: Exploring Genomic Signatures in Cervical Cancer | C. Pérez-Plasencia, Y. C. Orbe-Orihuela, Armando Méndez-Herrera, Jessica Deas, Claudia Gómez-Cerón, H. Jiménez-Wences, J. Ortiz-Ortiz, G. Fernández-Tilapa, Aldo F. Clemente-Soto, J. R. Parra-Unda, J. S. Velarde-Félix, M. Rodríguez-Dorantes, O. Peralta-Zaragoza | 2025-06-01 | Biomedicines | 0 | 33 |
visibility_off | Evolving Resistance: The Interplay of p53, Chemoresistance, and Metastasis in Cancer's Journey | Zenith Kwong | 2025-06-17 | MedScien | 0 | 0 |
visibility_off | Abstract P1-01-06: Whole-genome landscapes of 1,364 breast cancers with clinical outcomes | Ryul Kim, J. Yu, Joonoh Lim, Brian Baek-Lok Oh, S. Nam, S. Kim, Jeong-Eon Lee, Byung-Joo Chae, Ji-Yeon Kim, Ga Eun Park, Bong Joo Kang, Pil Sun Baek, Soo Yeon Bae, C.I. Yoon, Young Joo Lee, D. Kim, K. Shin, Ji Eun Lee, Jun Kang, Ahwon Lee, E. Connolly-Strong, Sangmoon Lee, Bo-Rahm Lee, Yuna Lee, Kijong Yi, Youngoh Kwon, In Hwan Chun, Jung-Woon Park, Jihye Kim, Chahyun Choi, Jong-Yeon Shin, Hyunjun Lee, Minji Kim, H. Park, Ilecheon Jeong, Boram Yi, W. Lee, Jeongmin Lee, Woo Chan Park, Sung Hun Kim, Yoon-La Choi, Jeongmin Lee, Young Seok Ju, Y. Park | 2025-06-13 | Clinical Cancer Research | 0 | 39 |
visibility_off | ONECUT2 reprograms neuroendocrine fate and is an actionable therapeutic target in small cell lung cancer | Mirian Gutiérrez, Irene Zamora, Raquel Iriarte, M. Pajares, Qian Yang, Chen Qian, N. Otegui, J. Fernández-Irigoyen, Enrique Santamaria, N. Alcala, A. Sexton-Oates, L. Fernandez-Cuesta, Miguel Barajas, Alfonso Calvo, Luis M. Montuenga, Beatrice S. Knudsen, Sungyong You, Michael R. Freeman, Ignacio J. Encío, Mirja Rotinen | 2025-06-11 | Molecular Medicine | 0 | 37 |
visibility_off | Exploring the m5C epitranscriptome of mRNAs in breast cancer cells through genome engineering and long-read sequencing approaches | Konstantina Athanasopoulou, P. Adamopoulos, P. Tsiakanikas, Andreas Scorilas | 2025-06-25 | Functional & Integrative Genomics | 0 | 16 |
visibility_off | A survey of human cancer-germline genes : linking X chromosome localization, DNA methylation and sex-biased expression in early embryos | A. Loriot, Julie Devis, Laurent Gatto, C. De Smet | 2025-05-23 | bioRxiv | 0 | 21 |
visibility_off | Genetic Mutations in Prostate Cancer: Insights and Implications | Chinenye Mary Okorochi, Frederick Olusegun Akinbo, Gerald Ikechi Eze, Kehinde Elizabeth Olukoya, Enoch Chibuike Okorochi, Austin Ifeanyi Obiozor, Uzochukwu Chimdindu Ibe, Simon Enenche Iyalla, Macpherson Ifeanyi Ukachukwu | 2025-05-30 | World Journal of Advanced Research and Reviews | 0 | 0 |
visibility_off | p53 status determines the epigenetic response to demethylating agents Azacitidine and Decitabine | Emma Langdale Hands, A. Wallmann, Gabrielle Oxley, Sophie Storrar, Rochelle D’Souza, Mathew Van de Pette | 2025-05-19 | bioRxiv | 0 | 5 |
visibility_off | Deciphering the tumor immune microenvironment: single-cell and spatial transcriptomic insights into cervical cancer fibroblasts | Zhiheng Lin, Youwei Zhou, Zhenran Liu, Wenyang Nie, Hengjie Cao, Shengnan Li, Xuanling Li, Lijun Zhu, Guangyao Lin, Yanyu Ding, Yi Jiang, Zuxi Gu, Lianwei Xu, Zhijie Zhao, Hua-Bao Cai | 2025-07-05 | Journal of Experimental & Clinical Cancer Research : CR | 0 | 9 |
visibility_off | tugMedi: simulator of cancer-cell evolution for personalized medicine based on the genomic data of patients | Iurii S. Nagornov, E. Furukawa, M. Nagai, S. Yagishita, Tatsuhiro Shibata, M. Kato | 2025-07-03 | bioRxiv | 0 | 18 |
visibility_off | Mechanism of age-related accumulation of mitochondrial DNA mutations in human blood | Rahul Gupta, Timothy J. Durham, Grant Chau, M. Uddin, Wenhan Lu, K. Karczewski, D. Howrigan, P. Natarajan, Wei Zhou, Benjamin M. Neale, V. Mootha | 2025-05-28 | bioRxiv | 0 | 101 |
visibility_off | Pediatric Cancer Genetics and Genomics. | Elaine R. Mardis | 2025-05-28 | Annual review of genomics and human genetics | 0 | 5 |
visibility_off | Abstract P4-10-26: PRISM high-throughput screening to elucidate how tumor microenvironments modulate drug responses of breast cancer cells | Blanche C. Ip, Jillian N. Eskra, Tenzing Sangpo, Ashish Bino George, M. Ronan, M. Rees, Jennifer A. Roth | 2025-06-13 | Clinical Cancer Research | 0 | 28 |
visibility_off | Genomic diversity in functionally relevant genes modifies neurodevelopmental versus neoplastic risks in individuals with germline PTEN variants | Adriel Y Kim, L. Yehia, Ch. Eng | 2025-05-20 | NPJ Genomic Medicine | 2 | 19 |
visibility_off | Targeting TP53TG1: a promising prognostic biomarker and therapeutic target for personalized cancer therapy | Haodong He | 2025-07-07 | Discover Oncology | 0 | 1 |
visibility_off | Abstract P3-05-23: Single nucleus chromatin accessibility and transcriptome analyses reveal aberrant inter-cellular communication in inflammatory breast cancer | H. Nakshatri, P. Bhat-Nakshatri, Cihat Erdogan, Hongyu Gao, Yunlong Liu | 2025-06-13 | Clinical Cancer Research | 0 | 67 |
visibility_off | Biological roles of enhancer RNA m6A modification and its implications in cancer | Yangyang Han, Jingqi Sun, Minghui Yao, L. Miao, Mengjia Li | 2025-05-30 | Cell Communication and Signaling : CCS | 0 | 1 |
visibility_off | HPV-driven cancers: a looming threat and the potential of CRISPR/Cas9 for targeted therapy | Atefeh Zamani Kermanshahi, Fatemeh Ebrahimi, Ahmad Taherpoor, Narges Eslami, H. B. Baghi | 2025-05-22 | Virology Journal | 0 | 25 |
visibility_off | Mechanistic Foundations of KRAS-Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment. | Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai | 2025-06-09 | Advanced science | 0 | 20 |
visibility_off | Selective targeting of genome amplifications and repeat elements by CRISPR-Cas9 nickases to promote cancer cell death | Matthew B Hanlon, Jason M Shohet, S. Wolfe | 2025-06-02 | Nature Communications | 0 | 54 |
visibility_off | LSH-mediated resolution of R-loops mitigates transcription-replication conflicts to preserve genomic stability in prostate cancer cells | Kai Ni, Yu Zhang, Kun Zheng, Jianwen Huang, Nuorong Xiong, Rong Liang, Yingxiao Chen, Honglin Jin, Youlong Hai, Wang Li, Jiayi Ma, Ranxing Yang, Guanggai Xia, Yueqing Bai, Lujie Song, Xiaoyong Hu, Zijian Tang, Qiang Fu | 2025-06-07 | bioRxiv | 0 | 10 |
visibility_off | Genetic modifiers of somatic expansion and clinical phenotypes in Huntington's disease highlight shared and tissue-specific effects. | Jong-Min Lee, Zachariah L. McLean, Kevin Correia, Jun Wan Shin, Sujin Lee, Jae-Hyun Jang, Yukyeong Lee, Kyung-Hee Kim, Doo Eun Choi, Jeffrey D. Long, D. Lucente, Ihn Sik Seong, Ricardo Mouro Pinto, James V. Giordano, J. Mysore, Jacqueline Siciliano, Emanuela Elezi, Jayla Ruliera, T. Gillis, V. Wheeler, M.E Macdonald, J. Gusella, Anna Gatseva, Marc Ciosi, Vilija Lomeikaite, Hossameldin Loay, Darren G. Monckton, Christopher Wills, Tom Massey, Lesley Jones, P. Holmans, Seung Kwak, Cristina Sampaio, Michael Orth, G. B. Landwehrmeyer, J. Paulsen, E. R. Dorsey, Richard H. Myers | 2025-06-09 | Nature genetics | 0 | 126 |
visibility_off | Tumor-associated macrophages contribute to cisplatin resistance via regulating Pol η-mediated translesion DNA synthesis in ovarian cancer | Bilash Chatterjee, Mrinmoy Sarkar, Debanjana Ghosh, Sangita Mishra, Subhankar Bose, Md Maqsood Ahamad Khan, Senthil Kumar Ganesan, Nabanita Chatterjee, A. K. Srivastava | 2025-05-29 | Cellular and Molecular Life Sciences: CMLS | 0 | 10 |
visibility_off | Epigenetic regulators in cancer therapy and progression | Hany E. Marei | 2025-06-28 | NPJ Precision Oncology | 0 | 2 |
visibility_off | Epigenetic Dysregulation in Cancer: Implications for Gene Expression and DNA Repair-Associated Pathways | Nina Rembiałkowska, Katarzyna Rekiel, Piotr Urbanowicz, Mateusz Mamala, Karolina Marczuk, Maria Wojtaszek, Marta Żywica, Eivina Radzevičiūtė-Valčiukė, V. Novickij, J. Kulbacka | 2025-07-01 | International Journal of Molecular Sciences | 0 | 35 |
visibility_off | The Primary Role of Noncoding RNA in the Pathogenesis of Cancer | Amil Shah | 2025-06-30 | Genes | 0 | 1 |
visibility_off | The Genetic and Evolutionary Landscape of Pentanucleotide Tandem Repeats in Human Genomes | Isaac R. L. Xu, D. Pellerin, L. V. D. Vondel, Matt C. Danzi, S. Züchner | 2025-05-27 | bioRxiv | 0 | 8 |
visibility_off | Repurposing of FDA‐Approved Drugs Against Leukemia by Targeting hDus2 | Anshuman Chandra, Monika Mukhija, Kanika Devi, Susmita Chaudhuri, P. Yadav, Vijay Kumar Goel | 2025-06-01 | ChemistrySelect | 0 | 25 |
visibility_off | Methylation dynamics in the decades preceding acute myeloid leukaemia | Adriana V.A. Fonseca, Christopher Boniface, Caroline J. Watson, Samuel Hackett, C. Gabbutt, Akemi D. Ramos-Yamasaki, Amanda B. Tan, Jose Montoya, R. Strogantsev, Lars L. P. Hanssen, Yuexuan Zhang, Sophia Apostolidou, A. Gentry-Maharaj, Sadik C Esener, Paul T Spellman, Trevor Graham, U. Menon, Hisham Mohammed, J. Blundell | 2025-06-27 | bioRxiv | 0 | 60 |
visibility_off | Dual-omic analysis to reveal gene regulatory network of immune landscape in childhood solid tumors and implications for immunotherapy. | Stéphanie Bianco, Anas Belaktib, Virgile Raufaste-cazavieille, Charles Joly-Beauparlant, Mona Patoughi, Thibault Mallevaey, Lara Herrmann, Sylvie Langlois, Thomas Sontag, Alex Richard-St-Hilaire, Noel Raynal, Vincent-Philippe Lavallée, Sonia Cellot, T. Tran, D. Sinnett, Arnaud Droit, Raoul Santiago | 2025-06-01 | Journal of Clinical Oncology | 0 | 12 |
visibility_off | Lineage memory shapes viral resistance barriers in human skin | Laura C. Van Eyndhoven, Grant Kinsler, Jingchao Zhang, Aoife O’Farrell, Rim Abderrahim, Apurv Srivastav, Catherine G. Triandafillou, Todd M. Greco, Kenneth S. Zaret, I. Cristea, Megan H. Orzalli, N. Drayman, Abhyudai Singh, Arjun Raj | 2025-06-27 | bioRxiv | 0 | 59 |
visibility_off | Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for β-hemoglobinopathies | S. Amistadi, L. Fontana, Chiara Magnoni, T. Felix, Matteo Kane Charvin, P. Martinucci, Candice Gautier, Lilian Greau, Bettina Bessières, P. Antoniou, O. Romano, Eric Allemand, C. Mussolino, A. Miccio | 2025-07-08 | Nucleic Acids Research | 0 | 29 |
visibility_off | Intratumoral Heterogeneity of Vimentin Modulates Nuclear Mechanotransduction, DNA Damage Response and Cancer Cell Survival | Infante Elvira, Terriac Emmanuel, Gelin Matthieu, Siegfried Hugo, Pereira David, Roca Vanessa, Varet Hugo, Khalilian Sara, Rietveld Reinier, Asnacios Atef, van Bodegraven Emma J, Etienne-Manneville Sandrine | 2025-06-28 | bioRxiv | 0 | 0 |
visibility_off | PHGDH drives 5-FU chemoresistance in colorectal cancer through the Hedgehog signaling | Caterina Mancini, Giulia Lori, Gianluca Mattei, Marta Iozzo, Dayana Desideri, Fabio Cianchi, Laura Fortuna, Federico Passagnoli, D. Massi, Filippo Ugolini, Luca Messerini, Salvatore Piscuoglio, Antonio Pezone, Francesca Magherini, A. Biagioni, T. Lottini, Demetra Zambardino, G. Truglio, Elena Petricci, Alberto Magi, A. Arcangeli, Luisa Maresca, Barbara Stecca, E. Pranzini, M.L. Taddei | 2025-07-10 | Journal of Experimental & Clinical Cancer Research : CR | 0 | 20 |
visibility_off | Abstract P1-07-14: MutL loss in ER+ breast cancer promotes pro-tumorigenic macrophage polarization that aids migration capacity | M. Raghunathan, A. Mazumder, Sabrina Carrell, D. Lozano, Nindo B Punturi, S. Haricharan | 2025-06-13 | Clinical Cancer Research | 0 | 17 |
visibility_off | Methylation-associated mutagenesis underlies variation in the mutation spectrum across eukaryotes | Fabián Ramos-Almodóvar, Ziyue Gao, Benjamin F. Voight, I. Mathieson | 2025-05-30 | bioRxiv | 0 | 38 |
visibility_off | TEITbase: a database for transposable element (TE)-initiated transcripts in human cancers | Yun Zhang, Jianqi She, Xueyan Hu, Yueqi Jin, Changyu Tao, Minghao Du, Ence Yang | 2025-06-25 | bioRxiv | 0 | 7 |
visibility_off | Genetic Analysis of Osteosarcoma Cells in a 9-year-old Boy: Genes Involved in Cell Cycle Control | Dragan Jovanovic, Alwajih Tariq, Sara Dlugos | 2025-06-20 | Acta Medica Academica | 0 | 0 |
visibility_off | DNA Damage and Repair in Glioblastoma: Emerging Therapeutic Perspectives | I. Gareev, O. Beylerli, S. Roumiantsev | 2025-07-01 | Creative surgery and oncology | 0 | 21 |
visibility_off | Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets | Yutao Li, Qingyun Liu, Xilin Jing, Yuqi Wang, Xiaohua Jia, Xing Yang, Kezhong Chen | 2025-07-01 | MedComm | 0 | 0 |
visibility_off | KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival | Thomas L. Ekstrom, Zhangshuai Dai, Julia Thiel, Meghana Manjunath, Nadine Schacherer, Bishakha Joyeeta Saha, Yara Souto, A. Abdelrahman, Frank Essmann, Sven Beyes, M. Truty, Meng Dong, Steven A. Johnsen | 2025-07-08 | bioRxiv | 0 | 42 |
visibility_off | A clinical solution for tracking clonal evolution of acute myeloid leukemia after allogeneic transplantation using bulk next generation sequencing. | Elizabeth F. Krakow, Nathan Lee, Isaac Jenkins, O. Sala-Torra, Lan W. Beppu, J. Radich, Bryce Fukuda, Brenda M Sandmaier, C. Yeung, Ivana Bozic | 2025-05-16 | Bone marrow transplantation | 0 | 93 |
visibility_off | Strategies for CRISPR-based knock-ins in primary human B cells and lymphoma cell lines | Sophie Lund, Chun Gong, Xin Yu, Louis M. Staudt, Daniel J Hodson, Sebastian Scheich | 2025-05-16 | Frontiers in Immunology | 0 | 13 |
visibility_off | Multigenerational cell tracking of DNA replication and heritable DNA damage | Andreas Panagopoulos, Merula Stout, Sinan Kılıç, Peter Leary, Julia Vornberger, Virginia Pasti, A. Galarreta, Aleksandra Lezaja, Kyra Kirschenbühler, Ralph Imhof, H. Rehrauer, Urs Ziegler, Matthias Altmeyer | 2025-05-21 | Nature | 1 | 42 |
visibility_off | [Rethinking cancer]. | W. R. Luo | 2025-05-28 | Zhonghua zhong liu za zhi [Chinese journal of oncology] | 0 | 0 |
visibility_off | Innovation and Implication of CRISPR-Mediated T-cell Engineering in Cancer Immunotherapy: A New Insight | Syeda Areej Imran, H. Sultan, Muhammad Zubair, S. Ghazanfar, Anas Islam, Syed Mustafizur Rahaman, Sumel Ashique | 2025-06-03 | Current Cancer Therapy Reviews | 0 | 20 |
visibility_off | Systematic identification and targeting of master regulator checkpoints (MRC) governing tumor microenvironment-mediated immune evasion | Pasquale Laise, G. Bosker, Mariana Babor, Xiaoyun Sun, Stuart Andrews, Lorenzo Tomassoni, Andrea Califano, Mariano J. Alvarez | 2025-06-01 | Journal for Immunotherapy of Cancer | 0 | 7 |
visibility_off | Tumor microenvironment heterogeneity and progression mechanisms in intrahepatic cholangiocarcinoma: A study based on single-cell and spatial transcriptomic sequencing. | Fengwei Li, Yao Li, Lishan Wang, Lei Xu, Hui Xue, Wenxin Wei, Yong Xia, Lei Wang, Feng Shen, Kui Wang | 2025-06-09 | Hepatology | 0 | 9 |
visibility_off | Drugging the 'undruggable' KRAS: breakthroughs, challenges, and opportunities in pancreatic cancer. | Nawaz Khan, Umar Raza, Syed Aqib Ali Zaidi, Muhadaisi Nuer, Kayisaier Abudurousuli, Yipaerguli Paerhati, Alifeiye Aikebaier, Wenting Zhou | 2025-07-07 | Cancer biology & medicine | 0 | 6 |
visibility_off | Gene DSCC1 is a Potential Biomarker in Pan-cancer | Jialing Jiang, Xiaolong Yan, Dan Huang, Jieyu Chen, Xiaodan Hao | 2025-05-29 | Journal of Contemporary Medical Practice | 0 | 0 |
visibility_off | The cancer-associated SF3B1K700E spliceosome mutation confers enhanced sensitivity to BV-6-induced cytotoxicity | Lydia E Roets, J. Blayney, Hayley McMillan, Patrick J Preston, Alexander Mutch, Ken I Mills, K. Savage, K. Lappin | 2025-07-01 | Cell Death & Disease | 0 | 23 |
visibility_off | Mutational and low-coverage whole genome sequencing identifies actionable DNA repair alterations in prostate cancer plasma DNA | A. Virga, Milena Urbini, Maurizio Polano, E. Petracci, G. Tedaldi, G. Gurioli, G. Marisi, D. Angeli, Andrea Ambrosini-Spaltro, Giovanni De Luca, Ilaria Cangini, Valentina Zampiga, Giovanna Cenacchi, Giuseppe Toffoli, C. Casadei, M. C. Cursano, V. Conteduca, U. de Giorgi, Paola Ulivi | 2025-07-01 | Scientific Reports | 0 | 59 |
visibility_off | MAPK and mTORC1 signaling converge on Cyclin D to enable cell-cycle re-entry in melanoma persister cells | Varuna Nangia, Humza M. Ashraf, Nasreen Marikar, Victor J. Passanisi, C. R. Ill, Sabrina L. Spencer | 2025-05-16 | bioRxiv | 0 | 10 |
visibility_off | Current advances in the role of classical non‐homologous end joining in hematologic malignancies | Pengcheng Liu, Zi-zhen Xu | 2025-05-29 | Clinical and Translational Discovery | 0 | 1 |
visibility_off | Abstract P5-06-19: Single-cell transcriptional features of human breast tumors and model systems | Julia E Altman, Amy L. Olex, Emily K. Zboril, Carson J Walker, David C. Boyd, Rachel K. Myrick, Nicole S Hairr, Jennifer E Koblinski, Madhavi Puchalapalli, Bin Hu, Mikhail G. Dozmorov, X. S. Chen, Yunshun Chen, C. Perou, B. Lehmann, Jane E. Visvader, J. Harrell | 2025-06-13 | Clinical Cancer Research | 0 | 164 |
visibility_off | Abstract P2-11-20: Discovering Co-driver Genes and Pathways of Mutant TP53 in Breast Cancer by CRISPR Screening and Multi-omics Approaches | Lilian Nwachukwu, Anasuya Pal, Yining Zheng, Laura González‐Malerva, Duatin Grief, Lydia Sakala, Jin G Park, Joshua LaBaer | 2025-06-13 | Clinical Cancer Research | 0 | 6 |
visibility_off | P-804 Improving CRISPR/Cas9 gene correction in early mouse embryos using RNase-resistant crRNA XT | S. Jooris, A. Rybouchkin, F. Jalali, J. Parrington, F. Vanden Meerschaut, T. Hochepied, K. Claes, D. Stoop, B. Heindryckx, B. Menten | 2025-06-01 | Human Reproduction | 0 | 12 |
visibility_off | Discovery of candidate functional non-coding mutations in acute myeloid leukemia using single-cell chromatin accessibility sequencing | Ming Zhu, Jiali Zhu, Zhijuan Zhu, Yiding Yang, Jinxian Dai, Hua Li, Nainong Li, Jialiang Huang | 2025-05-26 | Communications Biology | 0 | 1 |
visibility_off | Targeting Abnormal Methylation Enzymes: A New Approach to Cancer Therapy | Ming Liau, Chrinstine L. Craig, L. Baker | 2025-05-24 | Journal of Cancer and Tumor International | 0 | 2 |
visibility_off | DNA methylation remodeling in temozolomide resistant recurrent glioblastoma: comparing epigenetic dynamics in vitro and in vivo | Michela Buonaiuto, Mariella Cuomo, Davide Costabile, Federica Trio, Sara Ferraro, O. Affinito, Alberto De Bellis, Maria Laura Del Basso De Caro, Roberta Visconti, Lorenzo Chiariotti, Giuseppe Catapano, R. Della Monica | 2025-07-10 | Journal of Translational Medicine | 0 | 15 |
visibility_off | Germline-somatic liaison dictates cancer subtype via de novo steroid biosynthesis. | P. Gasperini, A. Alaimo, Blerta Stringa, Yoon-Mi Chung, Yari Ciani, F. Lorenzin, Giulia Fracassi, Y. Zekri, F. Orlando, Orsetta Quaini, Sebastian Gregoricchio, G. Petris, Antonio Casini, Christopher E Barbieri, W. Zwart, A. Cereseto, Nima Sharifi, Andrea Lunardi, F. Demichelis | 2025-06-13 | Cancer discovery | 0 | 47 |
visibility_off | METTL5 Blockade Enhances Anti-Tumor Immune Response via Inducing Neoantigen Generation | Yangyi Zhang, Xiaoyan Shi, Yuci Wang, Ruiqi Wang, Yanlan Cao, Hao Chen | 2025-06-07 | bioRxiv | 0 | 4 |
visibility_off | Cancer-Associated PIK3R1 Genetic Aberrations and Precision Medicine | Huan Xie, Yirong Li, Xinran Li | 2025-06-12 | International Journal of Medical Sciences | 0 | 3 |
visibility_off | Pathway Sculptor for Compact and Versatile Combinatorial Genetic Perturbation | Bo Gu, James M. Linton, Brice Graham Hendrickson, Hengyu Li, Ron Hadas, Gal Manella, Jan Gregrowicz, M. Elowitz | 2025-06-16 | bioRxiv | 0 | 63 |
visibility_off | ANP32E drives vulnerability to ATR inhibitors by inducing R-loops-dependent transcription replication conflicts in triple negative breast cancer | Sara Lago, V. Poli, Lisa Fol, Mattia Botteon, Federica Busi, Alice Turdo, Miriam Gaggianesi, Yari Ciani, Giacomo D’Amato, Luca Fagnocchi, A. Fasciani, F. Demichelis, Matilde Todaro, A. Zippo | 2025-05-17 | Nature Communications | 0 | 21 |
visibility_off | Progress in CRISPR Technology for Antiviral Treatments: Genome Editing as a Potential Cure for Chronic Viral Infections | Fatemeh Nouri, Farnaz Alibabaei, Behina Forouzanmehr, Hamed Tahmasebi, Valentyn Oksenych, Majid Eslami | 2025-05-20 | Microbiology Research | 0 | 19 |
visibility_off | The DNA-PKcs/JNK/p53 pathway underlies changes in cell fate decision toward death during DNA replication catastrophe | Jinal A. Patel, Julie Rageul, Natalie Lo, Auntara Nandi, Camryn Zezelic, Cynthia T Lee, Arafat Khan, Hyungjin Kim | 2025-06-20 | Nucleic Acids Research | 0 | 10 |
visibility_off | ZMYND8 promotes the Warburg effect and tumorigenesis through c-Myc activation in pancreatic cancer. | Hui Liu, Zhifeng Zhao, Changle Wu, Jinxin Chen, Zhiwei He, Kai Jiang | 2025-06-27 | Oncogene | 0 | 2 |
visibility_off | Single-Cell Transcriptomic Analysis Unveils Key Regulators and Signaling Pathways in Lung Adenocarcinoma Progression | Jialu Ma, Caleb McQuay, John Talburt, Amit K. Tiwari, Mary Qu Yang | 2025-06-30 | Biomedicines | 0 | 2 |
visibility_off | In-Silico Characterization of TP53 Splice Mutations in Somatic and Germline Tumours | Apeksha Arun Bhandarkar, Noah Ethan Kelly-Foleni, Debina Sarkar, Aaron Jeffs, Tania Slatter, Anthony Braithwaite, Sunali Y Mehta | 2025-06-01 | bioRxiv | 0 | 18 |
visibility_off | Abstract P1-02-25: New Murine Mammary Tumor Cell Lines for Syngeneic Studies Including Immunotherapy | Thomas J Kalantzakos, Anusha Soni, Cameron Durfee, Chris Mullally, Benjamin Troness, R. Harris, Harshita B. Gupta | 2025-06-13 | Clinical Cancer Research | 0 | 73 |
visibility_off | YTHDC1 orchestrates oncogenic splicing via the CLK1-SRSF1 splicing machinery to regulate castration-resistant prostate cancer progression. | Parth Gupta, Devesh Srivastava, Vinayak Nayak, B. V. Rao, K. Suseela, Rakesh Sharma, S. Rajappa, T. S. Rao, Parul Mishra, Ashish Misra | 2025-05-22 | Molecular and cellular biochemistry | 0 | 18 |
visibility_off | Dual ENPP1/ATM depletion blunts DNA damage repair boosting radioimmune efficacy to abrogate triple-negative breast cancer | Borja Ruiz-Fernández de Córdoba, K. Valencia, C. Welch, Haritz Moreno, S. Martínez-Canarias, C. Zandueta, Eduardo Gómez, Alfonso Calvo, N. Otegui, M. Echepare, Ignacio Garzón, D. Ajona, David Lara-Astiaso, Elisabet Guruceaga, Laura Guembe, Ruben Pio, I. Melero, Silve Vicent, Fernando Pastor, R. Martinez-Monge, F. Lecanda | 2025-06-13 | Signal Transduction and Targeted Therapy | 0 | 42 |
visibility_off | Exploring CRISPR Cloning and Beyond Through a Biochemical Lens in Genetic Biotechnology | Mariam Mariam, Khizra Ikhlaq, Zulaikha Abid, Fatima Sahar Uraf Maryam, Syed Qasim Mehmood, Ahtasham Ahmad, Sohrab Anwar Abbasi, Imran Ali Sani, Muhammad Adeel | 2025-07-02 | Scholars Academic Journal of Biosciences | 0 | 1 |
visibility_off | Comprehensive Measurement of Inter-Individual Variation in DNA Repair Capacity in Healthy Individuals | Ting Zhai, Patrizia Mazzucato, Catherine Ricciardi, David C. Christiani, Liming Liang, Leona D Samson, I. A. Chaim, Z. Nagel | 2025-06-16 | medRxiv | 0 | 22 |
visibility_off | Offspring effect of maternal preconception exposure to metabolic disruptors | Carlos Díaz-Castillo, Stephanie R. Aguiar, Raquel Chamorro-Garcia | 2025-05-27 | bioRxiv | 0 | 10 |
visibility_off | Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy | Yixing Wang, Jessica D Hess, Chen Wang, Lingzi Ma, Megan Luo, J. Jossart, John J. Perry, David Kwon, Zhe Wang, Xinyu Pei, Changxian Shen, Yingying Wang, Mian Zhou, Holly Yin, David Horne, A. Nussenzweig, Li Zheng, Binghui Shen | 2025-05-16 | ACS Chemical Biology | 0 | 30 |
visibility_off | Embryonic Stem Cell-Specific Responses to DNA Replication Stress | Ryan C. James, Jerry K. Wang, Siddhanth R. Bhatt, Sophie E. Shadid, Daryl J. Phuong, J. Schimenti | 2025-05-18 | bioRxiv | 0 | 60 |
visibility_off | Divergent FOXA1 mutations drive prostate tumorigenesis and therapy-resistant cellular plasticity. | Sanjana Eyunni, R. Mannan, Yuping Zhang, E. Young, Qiuyang Zhang, Jie Luo, Matthew Pang, Somnath Mahapatra, J. Tien, James M. George, Mustapha Jaber, Hamzah Hakkani, Sandra E Carson, Abigail J Todd, Noshad Hosseini, M. Gondal, Ryan J. Rebernick, Xuhong Cao, Fengyun Su, Rui Wang, Rohit Mehra, Jing Li, Marcin P. Cieslik, A. Chinnaiyan, A. Parolia | 2025-06-26 | Science | 0 | 169 |
visibility_off | RNA Through Time: From the Origin of Life to Therapeutic Frontiers in Transcriptomics and Epitranscriptional Medicine | Cecilia Martínez-Campos, Humberto Lanz-Mendoza, Jorge Cime-Castillo, O. Peralta-Zaragoza, Vicente Madrid-Marina | 2025-05-22 | International Journal of Molecular Sciences | 0 | 24 |
visibility_off | Prevalence and impact of molecular variation in the three-prime repair exonuclease 1 TREX1 and its implications for oncology | Marwa Shekfeh, Mariam M. Konaté, Julia Krushkal | 2025-06-28 | Human Genomics | 0 | 2 |
visibility_off | XPO1R749Q Mutations Co-occur with POLE Mutations in Cancer and can be Targeted to Overcome Chemoresistance. | T. Totiger, Wannasiri Chiraphapphaiboon, Y. Baca, S. Chaudhry, R. Notti, S. Montoya, M. Chojnacka, Gabriel Gaidosh, Jumana Afaghani, Maurizio Affer, Chris Armstrong, Paul M Kavanaugh, Efe Karaca, Jenna Zabroski, Michael Lewis, Alyssa Maye, Jacob Jahn, R. Soni, Daniel Bilbao, Phil Walker, Andrew Elliott, E. Lou, Wafik S. El-Deiry, Josean Rodriguez, Hai Dang Nguyen, Justin Taylor | 2025-06-18 | Cancer research | 0 | 13 |
visibility_off | Integrative Molecular Profiling of Oncogenic Pathways and Genetic Mutations in Cancer Progression and Therapeutic Response | Javeria Taj, Muhammad Noman Ajmal, Tayyaba Arshad, Afifa Dawood, Ali Abbas, Misbah Hafeez, Hamza Rafeeq, Abdul Malik, Aiman Nishat, Mujahid Hussain | 2025-06-20 | Scholars Academic Journal of Biosciences | 0 | 2 |
visibility_off | Competing Subclones and Fitness Diversity Shape Tumor Evolution Across Cancer Types | Haiming Chen, Jingmin Shu, Rekha Mudappathi, Elaine Li, Panwen Wang, Leif Bergsagel, Ping Yang, Zhifu Sun, Logan Zhao, Changxin Shi, Jeffrey P. Townsend, Carlo Maley, Li Liu | 2025-06-03 | bioRxiv | 0 | 5 |
visibility_off | Epigenetic modifications in follicular cell-derived thyroid cancer: new dimensions in pathogenesis and treatment | Yanmei Han, Bian Wu, Jie Tan, Ruolin Wu, Jingjing Wang, Xiaojing Ren, Yajing Zhang, Zairong Gao, Xiaotian Xia | 2025-05-20 | Frontiers in Oncology | 0 | 7 |
visibility_off | Are Mitochondria the True Origin of Cancer? A Hypothesis-Driven Perspective | Sergio Da Silva | 2025-07-01 | Onco | 0 | 5 |
visibility_off | Pituitary tumor transforming gene 1 and endocrine cancers: an up-to-date review through history, current insights and future perspectives. | E. Vergani, Emanuela Teveroni, Francesca Mancini, F. Di Nicuolo, S. Raia, S. Chiloiro, F. Pierconti, Antonio Bianchi, A. M. Isidori, Alfredo Pontecorvi, Domenico Milardi | 2025-06-01 | Endocrine-related cancer | 0 | 25 |
visibility_off | Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation | Sara Kirmani, T. Huan, J. V. Van Amburg, R. Joehanes, M. Uddin, N. Q. Nguyen, Bing Yu, Jennifer A. Brody, Myriam Fornage, Jan Bressler, N. Sotoodehnia, David A Ong, Fabio Puddu, James S Floyd, Christie M. Ballantyne, B. Psaty, L. Raffield, Pradeep Natarajan, Karen N Conneely, J. Weinstock, April P. Carson, Leslie Lange, Kendra R Ferrier, N. Heard-Costa, Joanne M Murabito, Alexander G. Bick, Daniel Levy | 2025-05-20 | Nature Communications | 0 | 77 |
visibility_off | Abstract P2-04-10: ARL3 Promotes Hormone Receptor Positive Breast Cancer Progression and Tamoxifen Resistance through ERα Stablization | Han Li, Yang Liu, Zehao Cai, Dan-hua Shu, Yang Peng, Kang Li, Shengchun Liu | 2025-06-13 | Clinical Cancer Research | 0 | 7 |
visibility_off | Loss of DHX36/G4R1, a G4 resolvase, drives genome instability and regulates innate immune gene expression in cancer cells | Anna R Bartosik, Pei-Chi Hou, Shangming Tang, James P. Vaughn, P. J. Smaldino, A. Ratan, Marty W. Mayo, Yuh-Hwa Wang | 2025-06-20 | Nucleic Acids Research | 0 | 39 |
visibility_off | In-depth analysis of the mode of action of resveratrol: genome-wide characterization of G-quadruplex binding properties | Ana Soriano-Lerma, Victoria Sánchez-Martín, Javier Murciano-Calles, Matilde Ortiz-González, Maria J. Tello-Lopez, Virginia Pérez-Carrasco, Ángel Linde-Rodríguez, Inmaculada Ramírez-Macías, Irene Gómez-Pìnto, Inmaculada López-Aliaga, M. Soriano, Jose A. Garcia Salcedo | 2025-06-20 | Cellular & Molecular Biology Letters | 0 | 12 |
visibility_off | ILF2 blockade suppresses helicase-mediated R-loop resolution to induce lethality in homologous recombination-deficient cancers | Yi Chieh Lim, Soak-Kuan Lai, Ru Han Yang, Yong Kang Chua, Rémi Patouret, Vaishnervi Manoj, Colin Chun Xuan Soh, Benjamin Lebeau, Ning Cham, Wei Meng, Sze Keong Tey, Szu Ling Yeap, Songjing Zhang, Jessie Yong Xing Woon, Zahin Ali, Marek Mutwil, Pritpal Singh, M. Fullwood, Linda LD Zhong, Xue Ming Dong, Chiba Shunsuke, Cheng-Gee Koh, Li Hoi Yeung | 2025-06-27 | bioRxiv | 0 | 14 |
visibility_off | Distinct genomic landscape of Lynch syndrome–associated urothelial cancer. | Jussi Nikkola, Lauri Ryyppö, Juuso Vuorinen, Lauri Moilanen, Maarit Ahtiainen, K. Pylvänäinen, Hanna Selin, Tuomo Virtanen, M. Nykter, T. Veitonmäki, J. Mecklin, T. Seppälä, M. Annala | 2025-06-01 | Journal of Clinical Oncology | 0 | 90 |
visibility_off | Human TLS DNA polymerase: saviors or threats under replication stress? | Y. S. Rajpurohit, Mitu Lal, D. K. Sharma, Ishu Soni | 2025-05-23 | Molecular and cellular biochemistry | 0 | 15 |
visibility_off | Generation of the ICGi019-B-1 and ICGi019-B-2 lines via correction of the p.Met659Ile (c.1977G>A) variant in MYH7 of patient-specific induced pluripotent stem cells using CRISPR/Cas9 | A. E. Shulgina, S. Pavlova, J. Minina, S. Zakian, E. V. Dementyeva | 2025-06-01 | Vavilov Journal of Genetics and Breeding | 0 | 22 |
visibility_off | Spatio-temporal patterns of active epigenetic turnover | Fabrizio Olmeda, Misha Gupta, Onurcan Bektaş, Steffen Rulands | 2025-05-19 | ArXiv | 0 | 3 |
visibility_off | Beyond the Limit: MYC Mediates Tumor Immune Escape | Zhongyang Hong, Sitong Ming, Xin Luan, Zhe Sun, Weidong Zhang | 2025-06-29 | Pharmaceuticals | 0 | 4 |
visibility_off | From mitosis to mutagenesis: Chromosomal passenger proteins at the crossroads of replication stress and cancer resilience | S. Knauer, Roland H. Stauber | 2025-07-07 | Cell Signaling | 0 | 40 |
visibility_off | Abstract P1-09-18: Activation of HERV-R is a biomarker of poor prognosis among rural Nigerian women with triple-negative breast cancer | Faruk Mohammed, Mohammed Daniyan, Ines Hosni, H. S. Musa, S. K. Owolabi, A. Umar, Y. Iliyasu, Rebecca Garnham, Jane Carr-Wilkinson, Sani Ibrahim, Kevin Petrie | 2025-06-13 | Clinical Cancer Research | 0 | 11 |
visibility_off | Single-cell multi-omics reveals that FABP1 + renal cell carcinoma drive tumor angiogenesis through the PLG-PLAT axis under fatty acid reprogramming | Yiqiu Wang, Yingchun Liang, Min Li, Jiayi Lu, Sian Zhou, Yaoyu Yu, Changwei Yang, Xinhuang Hou | 2025-06-16 | Molecular Cancer | 0 | 3 |
visibility_off | AURKA inhibition amplifies DNA replication stress to foster WEE1 kinase dependency and synergistic antitumor effects with WEE1 inhibition in cancers | Jong Woo Lee, Jackie Shi, Julian Barrantes, Pratima Chaurasia, Sundong Kim, S. Cruz-Gomez, Cindy Yang, Jianlei Gu, Hongyu Zhao, Dejian Zhao, Benjamin Schiff, Ansley Roche, Elizabeth B. Perry, Jeffrey P. Townsend, Gary M. Kupfer, Katerina Politi, E. Golemis, Barbara Burtness | 2025-05-29 | bioRxiv | 0 | 9 |
visibility_off | Genes of the “regulation of lymphocyte activation” pathway may influence immune cells infiltration in growth hormone secreting pituitary tumors | S. Chiloiro, Flavia Costanza, G. L. Scaglione, Filippo Russo, Carmela Nardelli, A. Giampietro, P. Mattogno, L. Lauretti, Guido Rindi, L. De Marinis, Marco Gessi, Antonio Bianchi, Francesco Doglietto, E. Capoluongo, Alfredo Pontecorvi | 2025-05-26 | Pituitary | 0 | 28 |
visibility_off | Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation | Andrew J Kristof, Krithika Karunakaran, Christopher Allen, Paula Mizote, Sophie Briggs, Zixin Jian, Patrick Nash, J. Blazeck | 2025-06-12 | Genome Biology | 0 | 0 |
visibility_off | Somatic p53 mutations that are markedly overrepresented in lung cancer confer resistance to ROS-induced cell death. | Mason A Tracewell, Jonathan Karlin, Samantha M. Barnada, Elizabeth L McDuffie, Charles P Scott, J. Barta, Steven B. McMahon | 2025-06-03 | Carcinogenesis | 0 | 11 |
visibility_off | Alternative splicing in human cells exposed to ionizing radiation: a comprehensive review of ex vivo and in vivo studies. | Jerónimo Leberle, Marina Perona, A. Choudhury, N. Bellora, Irene L Ibañez, Luisa V. Biolatti | 2025-05-22 | International journal of radiation biology | 0 | 25 |
visibility_off | Using long-read sequencing to detect and subtype a case with Temple syndrome | Sarah Dada, Vahid Akbari, Duha Hejla, Yaoqing Shen, Katherine Dixon, S. Choufani, Rosanna Weksberg, Cornelius F Boerkoel, Laura Stewart, Kamilla Schlade-Bartusiak, Emma Strong, Danya Fox, Daniel Gamu, William T. Gibson, Steven J M Jones | 2025-05-29 | Journal of Medical Genetics | 0 | 39 |
visibility_off | Multiple FGFR1 mutations modulate tumorigenic mechanisms in glioneuronal tumors | Jacopo Boni, Míriam Fernández-González, HyeRim Han, Carla Roca, Cassandra J. Wong, Cristina Rioja, C. Nogué, Leticia Manen-Freixa, J. Boulais, Endika Torres-Urtizberea, Antonio Gómez, M. Hasselblatt, R. Estrada-Tejedor, A. Antolin, Islam E. Elkholi, Nada Jabado, Jean-François Côté, A. Gingras, Barbara Rivera | 2025-05-28 | bioRxiv | 0 | 109 |
visibility_off | Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis | A. Pfaff, Sulev Kõks | 2025-06-03 | Experimental Biology and Medicine | 0 | 10 |
visibility_off | Clonal memory of cell division in humans diverges between healthy haematopoiesis and acute myeloid leukaemia | A. Donada, G. Hermange, T. Tocci, A. Midoun, G. Prevedello, L. Hadj Abed, D. Dupré, W. Sun, I. Milo, S. Tenreira Bento, C. Pospori, A. Innes, C. Willekens, J. Vargaftig, D. Michonneau, C. Lo Celso, N. Servant, KR Duffy, H. Isambert, PH Cournède, L. Laplane, L. Perie | 2025-06-24 | bioRxiv | 0 | 25 |
visibility_off | Implications of homologous recombination repair pathway mutations on the immune microenvironment in gastric cancer. | Feng Jin, Ping Jiang, Huayang Zhong, Zengjin Hu, Ning Gao | 2025-06-01 | Journal of Clinical Oncology | 0 | 0 |
visibility_off | CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade. | Cody M Rogers, Hardeep Kaur, Michelle L Swift, Vivek B Raina, Shuo Zhou, Ajinkya S Kawale, Shahrez Syed, Korilynn G Kelly, Angela M Jasper, Sameer Salunkhe, Youngho Kwon, Jeffrey Wang, Aida Badamchi Shabestari, J. Daley, Adam Sacks, M. Gaczynska, P. Osmulski, Yashpal Rawal, N. Tomimatsu, S. Gayther, K. Lawrenson, S. Burma, Elizabeth V. Wasmuth, Shaun K. Olsen, Weixing Zhao, R. Hromas, David S. Libich, Alexander V. Mazin, Daohong Zhou, E. Greene, Dipanjan Chowdhury, Patrick Sung | 2025-05-22 | Science | 0 | 84 |
visibility_off | Abstract P5-06-26: APOBEC3B And DNA Damage Repair As Synthetic Lethal Pairs | B. Stefanovska, Benjamin Troness, Kevin Lin, Chad Myers, R. Harris | 2025-06-13 | Clinical Cancer Research | 0 | 73 |
visibility_off | Macroscopic Analyses of RNA-Seq Data to Reveal Chromatin Modifications in Aging and Disease | Achal Mahajan, Francesca Ratti, Ban Wang, Hana El-Samad, James H. Kaufman, Vishrawas Gopalakrishnan | 2025-05-18 | bioRxiv | 0 | 11 |
visibility_off | Unveiling the differences in tumor immune microenvironment between KRAS -wildtype and KRAS -mutant pancreatic ductal adenocarcinoma. | Heidi Ko, S. Pabla, Michelle F Green, M. Senosain, Hardik Parikh, Erik Van Roey, Shuang Gao, Yamuna Pulivendula, P. DePietro, Stuti Kaushalkumar Patel, Kyle C. Strickland, R. Previs, Erin Newburn, Kamal S Saini, Alicia Dillard, Eric A Severson, Brian Caveney, Taylor J. Jensen, Shakti H. Ramkissoon, R. Seager | 2025-06-01 | Journal of Clinical Oncology | 0 | 28 |
visibility_off | R-loops shape chromatin architecture to promote balanced lineage allocation during differentiation | Chun-Hao Chao, T. Fazzio | 2025-06-25 | bioRxiv | 0 | 28 |
visibility_off | Abstract P3-04-17: 16q is a breast cancer suppressor arm | Sean E Egan, Idil Eda Temel, Yeji An, Katelyn J Kozma, Amanda J. Loch, Wei Wang | 2025-06-13 | Clinical Cancer Research | 0 | 8 |
visibility_off | Genes driving three-dimensional growth of immortalized cells and cancer | Mukta Basu, Jin-Fen Xiao, Saravana Kumar Kailasam Mani, Fangyuan Qu, Yongqi Lin, Jason Duex, Huihui Ye, Vanessa Neang, Dan Theodorescu | 2025-06-10 | Cell Death & Disease | 0 | 5 |
visibility_off | Dysregulation of the low-level replication stress response in transformed cell lines | S. Ragu, E. Dardillac, Sylvain Caillat, J. Ravanat, Bernard S. Lopez | 2025-06-06 | Scientific Reports | 0 | 69 |
visibility_off | Joint inference of mutational signatures from indels and single-nucleotide substitutions reveals prognostic impact of DNA repair deficiencies | Patricia Ferrer-Torres, Iván Galván-Femenía, Fran Supek | 2025-07-03 | Genome Medicine | 0 | 1 |
visibility_off | A Novel Framework for the Design of Minimized Epigenetic Clocks Using the Analysis of DNA Methylation Heterogeneity | S. E. Romanov, Dmitry I. Karetnikov, D. A. Kalashnikova, Denis E. Polivcev, Yakov A. Osipov, D. A. Maksimov, Polina A. Antoshina, Viktor V. Shloma, E. Samoilova, Alina A. Ivanova, Rustam F. Karimov, A. N. Tkalin, Alexander A. Shevchenko, V. Kalsin, V. Baklaushev, P. P. Laktionov | 2025-05-23 | International Journal of Molecular Sciences | 0 | 11 |
visibility_off | miR-196b strictly regulates and reliably predicts the response to cetuximab in colorectal cancer | Shiyun Chen, Zhaoli Tan, Yanli Lin, Fang Pang, Xiaojie Wu, Xiang Li, Yumeng Cui, Weiling Man, Ying Li, Yanghua Li, Lu Han, Miaomiao Gou, Zhikuan Wang, Guanghai Dai, Youliang Wang | 2025-05-25 | Cellular & Molecular Biology Letters | 0 | 12 |
visibility_off | Modified hTERT promoters-driven purine nucleoside phosphorylase-gene therapy in association with chemo- and targeted therapy in the context of ovarian cancer. | Quoc Manh Nguyen, Pierre-François Dupré, Mathieu Berchel, Marylène Lévêque, Sylvie Choblet-Thery, F. d’Arbonneau, T. Montier | 2025-06-27 | Cancer gene therapy | 0 | 32 |
visibility_off | Role of PLK4 inhibition in cancer therapy. | Kishore Banik, Thomas J Hayman | 2025-06-13 | Cancer metastasis reviews | 0 | 0 |
visibility_off | Damage and Misrepair Signatures: Compact Representations of Pan-cancer Mutational Processes | Caitlin F. Harrigan, Kieran R. Campbell, Quaid Morris, Tyler Funnell | 2025-06-01 | bioRxiv | 0 | 9 |
visibility_off | Investigation of a germline variant of uncertain significance (MRE11:c.1138C > T) identified by exome sequencing in a cancer-affected individual and co-segregation analysis in affected and unaffected family members. | Mohammadreza Saberiyan, Mohammad Reza Seyedtaghia, Elham Mojodi, A. Nejatizadeh | 2025-05-31 | Molecular biology reports | 0 | 23 |
visibility_off | Effects of PIK3CA Gene Modifications on Radiosensitivity in Colorectal Cancer Cells. | Ghazi Alsbeih, K. Al-Hadyan | 2025-06-01 | Asian Pacific journal of cancer prevention : APJCP | 0 | 10 |
visibility_off | Investigation of Structural Mechanisms Underlying p53 Dysfunction Caused by 148 Missense Mutations Using AlphaFold3 and Molecular Dynamics Simulations. | Khondamir R Rustamov, J. I. Razzokov, A. Baev | 2025-06-04 | Journal of chemical information and modeling | 1 | 10 |
visibility_off | MicroRNA-driven organ-specific metastasis in triple-negative breast cancer: biogenesis, mechanisms, and therapeutic approaches. | Deepshikha Rathore, Sweny Jain, Shanaya Patel, Nandani Dharwal, N. Shukla, Chirag Desai, Jigna Shah, Heena V. Dave | 2025-06-28 | Medical oncology | 0 | 3 |
visibility_off | A Bayesian Approach for Identifying Driver Mutations within Oncogenic Pathways through Mutual Exclusivity | Xinjun Wang, Caroline E. Kostrzewa, Allison Reiner, Ronglai Shen, Colin B Begg | 2025-05-31 | bioRxiv | 0 | 2 |
visibility_off | Predicting transposable element-derived neoantigens in ATRX-mutated sarcoma. | Simon Cao, Ziyang Wang, B. Nacev | 2025-06-01 | Journal of Clinical Oncology | 0 | 4 |
visibility_off | BRCA2 reversion mutation–independent resistance to PARP inhibition through impaired DNA prereplication complex function | Kyrie Pappas, Matteo Ferrari, Perianne Smith, S. Nandakumar, Zahra Khan, Serina B. Young, Justin Laclair, M. V. Russo, Emmet Huang-Hobbs, Nikolaus Schultz, W. Abida, Wouter Karthaus, M. Jasin, Charles L Sawyers | 2025-06-03 | Proceedings of the National Academy of Sciences of the United States of America | 0 | 100 |
visibility_off | Oxidative DNA Damage and Repair Dynamics in Multiple Sclerosis: Insights from Comet Assay Kinetics, Base Excision Repair Gene Expression, and Genotype Analysis | Beata Filipek, A. Macieja, Aleksandra Binda, Rafał Szelenberger, Leslaw Gorniak, Elżbieta Miller, Mariola Świderek-Matysiak, M. Stasiołek, Ireneusz Majsterek, Tomasz Popławski | 2025-05-24 | Biomolecules | 0 | 17 |
visibility_off | RNA G-quadruplexes: emerging regulators of gene expression and therapeutic targets. | Zukela Ruzi, Wei Zha, Huang Yuan Yuan, Jiaorui Liu | 2025-07-03 | Functional & integrative genomics | 0 | 5 |
visibility_off | RBM5 recruiting MGC32805 in a sandwich mode and inducing ΔFAS neoantigen and triggering FAS properties switch: implication in colorectal cancer. | Huizhe Wu, Xiaoyun Hu, Yilin Wang, Xianglong Zhu, Qing Zhao, Ying Zhao, Wanlin Cui, Mingrong Zhang, Haishan Zhao, Kai Li, Minjie Wei | 2025-06-26 | Oncogene | 0 | 30 |
visibility_off | CREPT is required for the metastasis of triple-negative breast cancer through a co-operational-chromatin loop-based gene regulation | Jianghua Li, Lu Xu, Jiayu Wang, Xuning Wang, Yuting Lin, Alex Yutian Zou, Fangli Ren, Yinyin Wang, Jun Li, Zhijie Chang | 2025-06-10 | Molecular Cancer | 0 | 3 |
Abstract | Title | Authors | Publication Date | Journal/Conference | Citation count | Highest h-index |