Drug-Resistance forecasting

This page was last updated on 2025-10-13 09:31:47 UTC

Manually curated articles on Drug-Resistance forecasting

Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations
visibility_off Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations in mismatch repair genes in methotrexate-resistant HT-29 cells Ahreum Kim, Jong-Yeon Shin, Jeong-Sun Seo 2020-02-27 Experimental & Molecular Medicine, Experimental and Molecular Medicine 5 49 open_in_new
visibility_off Cellular adaptation to cancer therapy along a resistance continuum. Gustavo S. França, Maayan Baron, B. King, Jozef P Bossowski, Alicia Bjornberg, Maayan Pour, A. Rao, Ayushi S. Patel, Selim Misirlioglu, Dalia Barkley, Kwan Ho Tang, Igor Dolgalev, D. A. Liberman, Gal Avital, Felicia Kuperwaser, Marta Chiodin, Douglas A. Levine, T. Papagiannakopoulos, A. Marusyk, T. Lionnet, Itai Yanai 2024-07-10 Nature 62 45 open_in_new
Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations

Abstract Title Authors Publication Date Journal/Conference Citation count Highest h-index
visibility_off Adaptive cancer therapy: can non-genetic factors become its achilles heel? Gábor Valcz, Robert A. Gatenby, B. Újvári, E. Buzás, Béla Molnár 2025-09-22 Oncogene 0 4
visibility_off Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance Haiyin Li, Yeqing Chen, Jessica Kaster, Maggie Dunne, Min Xiao, Ling Li, Monzy Thomas, Nazifa Promi, Dylan Fingerman, G. Brown, Qiuxian Zheng, Xingyue Zhu, McKenna Reale, Andrew Patterson, Le Gao, Xuxiang Zhang, Siqi Jiang, Tianxing Hu, Hanzhang Fang, Jianlan Ren, Cong Qi, Luyang Wang, Haiwei Mou, Gatha Thacker, Eric Ramirez Salazar, J. Villanueva, Arjun Raj, Dave SB Hoon, Tian Bin, Jozef Madzo, Zhi Wei, Noam Auslander, M. Herlyn 2025-09-19 bioRxiv 0 117
visibility_off Advances in biomarkers of resistance to KRAS mutation-targeted inhibitors Lihao Wang, Dandan Wei, Shanshan Li, Shiqing Jiang 2025-10-08 Discover Oncology 0 0
visibility_off Cancer Metabolism Meets DNA Repair: The Hidden Link to Therapy Resistance. Chunzhang Yang 2025-09-28 BioEssays : news and reviews in molecular, cellular and developmental biology 0 2
visibility_off Resistance signatures manifested in early drug response across cancer types and species Cole Ruoff, Allison V. Mitchell, Priya Mondal, Vishaka Gopalan, Arashdeep Singh, MM Gottesman, Sridhar Hannenhalli 2025-08-26 Cancer Drug Resistance 0 7
visibility_off Long-read sequencing of single cell-derived melanoma subclones reveals divergent and parallel genomic and epigenomic evolutionary trajectories Yuelin Liu, Anton Goretsky, A. Keskus, S. Malikić, Tanveer Ahmad, Farid E. Michael Gertz, Rashidi Mehrabadi, Michael Kelly, Maria Hernandez, Charlie Seibert, J. M. Caravaca, Kayla Kline, Yongmei Zhao, Ying Wu, Biraj Shrestha, Bao Tran, Arindam Ghosh, Xiwen Cui, Antonella Sassano, Lakshay Malik, Breeana Baker, Cornelis Blauwendraat, Kimberley J. Billingsley, Eva Pérez-Guijarro, Glenn Merlino, Erin K. Molloy, S. C. Sahinalp, Chi-Ping Day, M. Kolmogorov, Contents 2025-09-02 bioRxiv 0 21
visibility_off Cancer cell plasticity and therapeutic resistance: mechanisms, crosstalk, and translational perspectives Saeid Ghorbian 2025-09-26 Hereditas 0 0
visibility_off The synergistic action of HDAC inhibitor with cisplatin impedes survival and proliferation of drug-tolerant persister in gastric and liver cancer cells Anjali Singh, Abhiram Natu, Flevia Anthony, Hemalatha Muthu, B. Khade, Duane T. Smoot, Hassan Ashktorab, Sanjay Gupta 2025-10-08 Clinical Epigenetics 0 9
visibility_off Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA. Marc J. Williams, I. Vázquez-García, Grittney K. Tam, Michelle Wu, Nancy Varice, Eliyahu Havasov, Hongyu Shi, Duaa H Al-Rawi, Gryte Satas, Hannah Lees, J. Lee, Matthew A. Myers, Matthew Zatzman, Nicole Rusk, Emily Ali, Ronak H Shah, Michael F. Berger, Neeman Mohibullah, Yulia Lakhman, Dennis S Chi, N. Abu-Rustum, Carol Aghajanian, Andrew McPherson, Dmitry Zamarin, Brian Loomis, Britta Weigelt, C. Friedman, Sohrab P. Shah 2025-10-01 Nature 0 90
visibility_off Patient-Derived Tumor Organoids to Model Cancer Cell Plasticity and Overcome Therapeutic Resistance R. Coppo, Masahiro Inoue 2025-09-01 Cells 0 7
visibility_off Abstract B120: Mapping and modulating epithelial-mesenchymal plasticity under RAS(ON) multi-selective inhibition in PDAC through lineage tracing and Perturb-seq Julien Dilly, Mike Bogaev, Lynn Bi, Abigail Collins, Martin Jankowiak, Aziz Al’Khafaji, Kyle E Evans, M. Babadi, Thouis R. Jones, Elisa Donnard, David T Ting, N. Hacohen, D. Pe’er, Eric S. Lander, A. Aguirre, Arnav Mehta 2025-09-28 Cancer Research 0 114
visibility_off LEVERAGING ORGANOID TECHNOLOGIES TO CHARACTERIZE DYNAMIC TUMOR CELL STATES DRIVING TREATMENT RESISTANCE IN PANCREATIC CANCER 2025-08-21 European Journal of Histochemistry 0 0
visibility_off EZH2-TTP-mTORC1 Axis Drives Phenotypic Plasticity and Therapeutic Vulnerability in Lethal Prostate Cancer Leigh Ellis, Beatriz German, Katherine L. Morel, Teia Noel, Nadia Boufaied, Deborah L. Burkhart, Sujun Chen, Felipe Dezem, Xintao Qiu, H. Long, Stefan DiFazio, S. Baca, Ayesha Shafi, Matthew L Freedman, H. Beltran, Christopher J Sweeney, H. He, Myles Brown, Jasmine T Plummer, Simon Knott, David Labbé 2025-08-21 Research Square 0 30
visibility_off Abstract B103: Defining cancer cell states that drive inflammation tolerance and KRAS inhibitor resistance in pancreatic cancer Yuzhou Evelyn Tong, Aswanth Mahalingam, Zixin Chen, Jacob Smigiel, Tsukasa Shibue, Andew Navia, Alex K. Shalek, Lorin Crawford, Ava P. Amini, Peter S. Winter, Srivatsan Raghavan 2025-09-28 Cancer Research 0 9
visibility_off Integrative proteo-genomic profiling uncovers key biomarkers of lapatinib resistance in HER2-positive breast cancer. J. Steggall, V. Rajeeve, N. Al-Subaie, A. Naeem, A. Ikram, A. Naeem, A. Hayat 2025-09-13 British journal of cancer 0 21
visibility_off Identification of malignant cells in single-cell transcriptomics data M. Andreatta, J. Garnica, Santiago J. Carmona 2025-08-22 Communications Biology 0 28
visibility_off A complete diploid human genome benchmark for personalized genomics Nancy F. Hansen, Nathan Dwarshuis, Hyun Joo Ji, A. Rhie, Hailey Loucks, Glennis A. Logsdon, Mitchell R. Vollger, Jessica M. Storer, Juhyun Kim, Eleni Adam, Nicolas Altemose, D. Antipov, Mobin Asri, Sofia Barreira, Stephanie C. Bohaczuk, Andrey V. Bzikadze, S. A. Carioscia, Andrew Carroll, Kuan-Hao Chao, Yanan Chu, Arun Das, Peter Ebert, A. English, M. Fleharty, Laura E. Fleming, G. Formenti, A. Guarracino, Gabrielle Hartley, Katharine M. Jenike, Jenna Kalleberg, Yu Kang, Robert King, Josipa Lipovac, Mira Mastoras, Matthew W. Mitchell, S. Negi, Nathan D. Olson, Keisuke K. Oshima, L. F. Paulin, Brandon D. Pickett, David Porubsky, Jane Ranchalis, D. Ranjan, M. Rautiainen, Harold Riethman, Robert D Schnabel, F. Sedlazeck, Kishwar Shafin, M. Šikić, Steven J. Solar, Alex Sweeten, W. Timp, Justin Wagner, DongAhn Yoo, Ying Zhou, Erik Garrison, E. Eichler, Michael C Schatz, Andrew B. Stergachis, Rachel J. O’Neill, K. Miga, Steven L Salzberg, S. Koren, J. Zook, A. Phillippy 2025-09-21 bioRxiv 1 81
visibility_off Identification of a CD138-negative therapy-resistant subpopulation in multiple myeloma with vulnerability to splicing factor inhibition. Takahiro Kamiya, Masahiko Ajiro, M. Oshima, S. Koide, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Akiho Tsuchiya, Satoshi Kaito, Naoki Itokawa, Ryoji Ito, Kiyoshi Yamaguchi, Yoichi Furukawa, Bahityar Rahmutulla, Atsushi Kaneda, Takayuki Shimizu, N. Doki, Taku Kikuchi, Nobuhiro Tsukada, Masayuki Yamashita, Shinichiro Okamoto, Akihide Yoshimi, Keisuke Kataoka, Atsushi Iwama 2025-09-02 Blood cancer discovery 0 30
visibility_off Single-cell transcriptome analysis reveals regulatory programs associated with tumor resistance during immunotherapy in colorectal cancer. Yan Chen, Tao Liu, Guangtao Min, Cong Wang, Dali Xi, Lei Jiang 2025-09-10 International journal of surgery 0 1
visibility_off Genomic Insights into Tumorigenesis in Newly Diagnosed Multiple Myeloma Marina Kyriakou, C. Papaloukas 2025-08-23 Diagnostics 0 24
visibility_off The Approaching Darwinian Era in Oncology. Robert A. Gatenby 2025-09-15 Cancer research 0 4
visibility_off Leveraging selection for function in tumor evolution: System-level cancer therapies F. Thomas, Jean-Pascal Capp, A. Dujon, A. Marusyk, K. Asselin, M. Campone, Pascal Pujol, Catherine Alix-Panabières, Benjamin Roche, B. Újvári, Robert Gatenby, A. Nedelcu 2025-08-18 Evolution, Medicine, and Public Health 0 29
visibility_off Targeting the crosstalk of metabolism reprogramming and replication stress: novel strategy to combat cancer. Wenbo Liu, Xiangyan Jiang, Yong Ma, Huiguo Qing, Yingcun Bao, Zuoyi Jiao 2025-09-26 Medical oncology 0 10
visibility_off Genomic Intelligence and Resistance Evolution: Redefining Oncotherapeutic Strategies in Precision Oncology Muchukota Sushma, Bharathi Bhogenahalli Venkatappa, Gowthami V., Nigel Viju Thomas, Souman Samanta 2025-08-28 International Journal of Innovative Science and Research Technology 0 0
visibility_off RNA sequencing reveals transcriptional signatures of drug response and SARS-CoV-2 interaction in colorectal cancer cells Alaa K. Hameed, Ifad K. Abd Al-Shibly, Rana A. Ghaleb 2025-09-18 Frontiers in Medicine 0 1
visibility_off Transition between cell states of sensitivity reveals molecular vulnerability of drug-tolerant cells. L. Peyre, Marielle Péré, Mickael Meyer, Benjamin Bian, Marina Moureau-Barbato, Walid Djema, B. Mari, Georges Vassaux, Jérémie Roux 2025-10-01 Molecular systems biology 0 11
visibility_off Analysis of Microarray and Single-Cell RNA-Seq Finds Gene Co-Expression and Tumor Environment Associated with Extracellular Matrix in Epithelial–Mesenchymal Transition in Prostate Cancer Ali Shakeri Abroudi, Mahtab Mashhouri Moghaddam, Danial Hashemi Karoii, Melika Djamali, Hossein Azizi, Thomas Skutella 2025-09-01 International Journal of Molecular Sciences 1 10
visibility_off Functional phenotyping of genomic variants using joint multiomic single-cell DNA–RNA sequencing Dominik Lindenhofer, Julia R. Bauman, John A. Hawkins, Donnacha Fitzgerald, Umut Yildiz, Haeyeon Jung, Anastasiia Korosteleva, Mikael Marttinen, M. Kueblbeck, Judith B. Zaugg, K. Noh, Sascha Dietrich, W. Huber, O. Stegle, Lars M. Steinmetz 2025-09-01 Nature Methods 0 88
visibility_off OS05.2.A DECIPHERING THE LONGITUDINAL TRAJECTORIES OF GLIOBLASTOMA ECOSYSTEMS BY INTEGRATIVE SINGLE-CELL GENOMICS A. Spitzer, K Johnson, M. Nomura, L. Garofano, D. Nehar-Belaid, N. Galili Darnell, A. Greenwald, L. Bussema, Y. Oh, F. Varn, F. D’Angelo, S. Gritsch, K J Anderson, S. Migliozzi, L. G. Gonzalez Castro, T. Chowdhury, N. Robine, C. Reeves, J. Park, A. Lipsa, F. Hertel, A. Gołȩbiewska, S. Niclou, L. Nusrat, S. Kellett, S. Das, H. Moon, S. Paek, F. Bielle, A. Laurenge, A. D. Di Stefano, B. Mathon, A. Picca, M. Sanson, S Tanaka, N. Saito, D. M. Ashley, S. Keir, K. L. Ligon, J. Huse, W. Yung, A. Lasorella, A. Iavarone, R. Verhaak, I. Tirosh, M. Suvà 2025-10-01 Neuro-Oncology 0 53
visibility_off Precision epigenetic therapies in oncology Arundhati Chaudhary, Kayleigh J A Orchard, F. Salani, Theodora Partsou, Mark Eccleston, Guido Bocci, A. Italiano, Francesco Crea 2025-09-19 Cancer Metastasis Reviews 0 43
visibility_off Drug discovery for chemotherapeutic resistance based on pathway-responsive gene sets and its application in breast cancer Dehua Feng, Jingwen Hao, Lingxu Li, Jian Chen, Xinying Liu, Ruijie Zhang, Huirui Han, Tianyi Li, Xuefeng Wang, Xia Li, Lei Yu, Bing Li, Jin Li, Limei Wang 2025-09-16 Frontiers in Bioinformatics 0 6
visibility_off Targeting Glioblastoma Cell State Plasticity for Enhanced Therapeutic Efficacy. S. Cirigliano, R. Singhania, James G Nicholson, Isha Monga, Yushan Wan, C. Haywood, Ashlesha Muley, Skylar A. Giacobetti, Howard A. Fine 2025-09-15 bioRxiv : the preprint server for biology 0 10
visibility_off Rad53 orchestrates divergent pathways governing genotoxic resistance, morphogenesis, and virulence in Candida albicans: Mechanistic decoupling through overexpression analysis. Jia Wang, Shaling Yang, Yi Zhou, Huaxin Cai, Jinrong Feng 2025-10-06 Virulence 0 2
visibility_off Metabolic Plasticity and Cancer Stem Cell Metabolism: Exploring the Glycolysis-OXPHOS Switch as a Mechanism for Resistance and Tumorigenesis Li Qing Keoh, Ching-Feng Chiu, T. S. Ramasamy 2025-08-29 Stem Cell Reviews and Reports 0 18
visibility_off Single-cell RNA sequencing reveals immune regulatory mechanisms and molecular therapeutic strategies in the microenvironment of multiple myeloma. Qiang Su, Kehan Long, Mozili Adu, Meijun Jiang, Qiaochu Li, Xufeng Wan, Jian Cao, Yan Yue, Shuoyuan Li, Zhendong Ying, Qibin Liu, Chaoqun You, Zhuang Zhang, Duan Wang 2025-09-03 International journal of surgery 0 6
visibility_off BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies Kyeong Beom Jo, M. Alruwaili, Da-Eun Kim, Yongjun Koh, Hyeyeon Kim, Kwontae You, Ji-Sun Kim, Saba Sane, Yanqi Guo, Jacob P. Wright, H. Lim, Maricris N. Naranjo, Atina G. Coté, Frederick P. Roth, David E. Hill, Jung-Hyun Choi, Hunsang Lee, Kenneth A. Matreyek, Kyle K.-H. Farh, Jong-Eun Park, Hyunkyung Kim, Andrei V. Bakin, Dae-Kyum Kim 2025-09-07 bioRxiv 0 20
visibility_off Hypoxia-drives reversible cell cycle arrest in lung cancer cells via modulation of cellular redox and gene expression D. Maurya, Varshita Mehta, Babita Singh 2025-09-29 Medical Oncology (Northwood, London, England) 0 24
visibility_off Engineering Cancer Resistance: A Novel Framework Inspired by Evolutionary Adaptations Hafiz Muhammadismail Azher Syed 2025-09-29 Wah Academia Journal of Health and Nutrition 0 0
visibility_off A Multi-Layered Atlas of Spatial Regulatory Programs and Therapeutic Vulnerabilities in Glioblastoma Linan Zhang, Matthew Lu, Xiaojun Ma, H. Osmanbeyoglu 2025-09-27 bioRxiv 0 2
visibility_off Metabolic plasticity drives specific mechanisms of chemotherapy and targeted therapy resistance in metastatic colorectal cancer Mariam Rojas, Malena Manzi, S. Madurga, Fernando Enrique García Velásquez, Maira Alejandra Romero, Silvia Marín, Marta Cascante, Joan Maurel 2025-09-23 Exploration of Targeted Anti-tumor Therapy 0 21
visibility_off Integration of Metabolic Profiling and Functional Genomics Suggests IGJ as a Driver of Chemoresistance in B-ALL. Karen Lizeth Pachón-Meza, Camilo Ernesto Moreno-Cristancho, José Luis Padilla-Agudelo, Ana Isabel Ramos-Murillo, Diana Londoño-Barbosa, Gustavo Salguero, S. Sanabria-Barrera, Claudia Chica, Nataly Cruz-Rodriguez, Rubén Darío Godoy-Silva, J. A. Gutiérrez-Triana 2025-10-06 Pediatric blood & cancer 0 9
visibility_off Methodological Comparison of Short-Read and Long-Read Sequencing Methods on Colorectal Cancer Samples Nikolett Szakállas, Alexandra Kalmár, K. Rada, M. Kucarov, Tamás Richárd Linkner, B. Barták, István Takács, Béla Molnár 2025-09-01 International Journal of Molecular Sciences 0 2
visibility_off Emerging insights into alternative end‑joining: Mechanisms, genome instability and therapeutic opportunities in cancer (Review). Nasir Azam, Xiangyu Liu, Xinghan Li, Lin Ma, Qi Liu 2025-10-09 International journal of oncology 0 2
visibility_off Distinct adaptive strategies to cisplatin, vinblastine and gemcitabine in a panel of chemoresistant bladder cancer cell lines Monika Cuprych-Belter, Agnieszka Łupicka-Słowik, Artur Anisiewicz, Martin Michaelis, J. Cinatl jr., Mateusz Psurski 2025-09-12 Cancer Drug Resistance 0 13
visibility_off Cryo-mtscATAC-seq for single-cell mitochondrial DNA genotyping and clonal tracing in archived human tissues Maren Salla, B. Obermayer, Marie Cotta, Ekaterina Friebel, Juliana Campo-Garcia, Georgia Charalambous, Roemel Jeusep Bueno, Dustin Lieu, Patryk Dabek, Ashley Helmuth, George Tellides, Roland Assi, Katrin Bankov, Marco Lodrini, H. Deubzer, D. Beule, Hattie Chung, Helena Radbruch, David Capper, Frank L. Heppner, Sarah C. Starossom, Caleb A. Lareau, Ilon Liu, Leif S. Ludwig 2025-09-20 bioRxiv 0 36
visibility_off Strict retroelement regulation is frequently lost following cancer transformation and generates a promising reservoir of cancer biomarkers Eric Russ, Sergey Iordanskiy 2025-10-03 Mobile DNA 0 2
visibility_off DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution F. Gimeno-Valiente, C. Castignani, E. Larose Cadieux, Nana E. Mensah, Xiaohong Liu, Kezhong Chen, O. Chervova, Takahiro Karasaki, C.E. Weeden, Corentin Richard, Siqi Lai, Carlos Martínez-Ruiz, E. Lim, A. Frankell, T. Watkins, Georgia Stavrou, Ieva Usaite, Wei-Ting Lu, Daniele Marinelli, S. Saghafinia, G. Wilson, P. Dhami, H. Vaikkinen, Jonathan Steif, S. Veeriah, R. Hynds, Martin Hirst, C. Hiley, A. Feber, Özgen Deniz, M. Jamal-Hanjani, N. Mcgranahan, Stephan Beck, J. Demeulemeester, M. Tanić, C. Swanton, P. Van Loo, N. Kanu 2025-09-01 Nature Genetics 0 70
visibility_off MNDA promotes immunosuppression in microsatellite instability-high colorectal cancer by facilitating PMN-MDSC infiltration via H3K18 lactylation Xuan Zhang, Wen-Bin Wang, Xin-Yi Cai, Xiao-Qiong Chen, Qing Feng, Quan Yang, Ji-Biao Li, Wei Xiong, Tao Wu 2025-10-03 Journal of Translational Medicine 0 7
visibility_off Population transcriptomics: a novel tool for studying genetic diversity in human populations under normal and pathological conditions A. A. Babovskaya, E. A. Trifonova, V. A. Stepanov 2025-09-01 Vavilov Journal of Genetics and Breeding 0 1
visibility_off MAIT Cells with High PFN1 Expression Mediate Immune Activation and Metabolic Reprogramming in Psoriasis Man-Ning Wu, Yue-Min Zou, Xiang-Nan Zhou, Sangwon Hong, Lei Wang, Yan-Ping Bai 2025-09-09 Clinical, Cosmetic and Investigational Dermatology 0 0
visibility_off The mutation landscape of Daphnia obtusa reveals evolutionary forces shaping genome stability Ruyun Deng, Feng Guo, Wen Wei, M. Pfrender, Jeff L. Dudycha, Michael Lynch, Zhiqiang Ye 2025-09-19 bioRxiv 0 37
visibility_off Epigenetic and transcriptional programs define osteosarcoma subtypes and establish targetable vulnerabilities. E. López-Fuentes, Andrew S Clugston, Alex G Lee, L. Sayles, Natalie Sorensen, María V Pons Ventura, Stanley G Leung, Truc Dinh, Marcus R. Breese, E. Sweet-Cordero 2025-10-03 Cancer discovery 0 17
visibility_off From Cancer Drivers to Cancer Keepers: Paradigm Shift and Clinical Implications Xizhe Zhang, Weixiong Zhang 2025-08-22 ArXiv 0 8
visibility_off P01.18.B MODELING GLIOBLASTOMA TREATMENT RESPONSES: INSIGHTS INTO TUMOR PLASTICITY AND THE ROLE OF THE TUMOR MICROENVIRONMENT M. de Lucas Sanz, H. Allahverdi, B. Nosirov, P. Moreno Sánchez, M. Baroni Milan, A. Lipsa, M. Rezaeipour, C. Dording, D. Brown, J. M. Langlands, K. Grzyb, Y. Yabo, J. Zhang, D. Heiland, A. Michelucci, P. Nazarov, A. Gołȩbiewska 2025-10-01 Neuro-Oncology 0 28
visibility_off Fusion Gene Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia. Polina K Derevyanko, L. Swart, L. D. Mata Casimiro, Anita van Oort, M. Du Plessis, Luca van den Brink, Minoo Ashtiani, C. Zwaan, A. Krippner-Heidenreich, Constanze Bonifer, Raymond Schiffelers, Josef Vormoor, S. Kellaway, Olaf Heidenreich 2025-09-24 Blood 0 9
visibility_off Multi-omics reveals immune features in immune and non-immune cells, an IFN-γ/IFN-α-B2M positive feedback loop, and targeted metabolic therapy in multiple myeloma Chen Li, Yaping Liao, Ling Xu, Yan Chen 2025-09-08 Frontiers in Immunology 0 1
visibility_off Genetic and transcriptomic alterations underlying aggressiveness in 5-fluorouracil-resistant HCT116 cells. Pornchai Sooksaen, A. Thim-uam, Ratsada Praphasawat, Chutamas Thepmalee, Kanokkarn Phromnoi, Damratsamon Surangkul, Surisak Prasarnpun, Chakkraphong Khonthun 2025-10-10 Medical oncology 0 13
visibility_off SH3BP5-driven metabolic-immune crosstalk in DLBCL: a prognostic biomarker and therapeutic target for reshaping immunosuppressive microenvironment Tong Wu, Yi Yang, Yuan Zong, Jiawen Zhao, Xiaoyu Zhao, Lei Li, Yiming Gao, Ning Li, Liting Jiang, Yinyin Xie 2025-09-24 Journal of Translational Medicine 0 9
visibility_off Integrated single-cell and bulk transcriptome analysis revealed high plasticity subpopulation and promising diagnosis model for clear cell renal cell carcinoma Zhongwen Lu, Fanyi Kong, Jiahuan Sun, Jing Ge, Jiajin Wu, Kunpeng Wang 2025-09-30 Hereditas 0 0
visibility_off The interplay of DNA damage, epigenetics and tumour heterogeneity in driving cancer cell fitness Celia D Rouault, E. Charafe-Jauffret, C. Ginestier 2025-09-30 Nature Communications 0 56
visibility_off Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing Wen Chen, Jiawei Xu, Chengdong Yu, Meng Zhou, Yong Ai, Wenbing Rao, Qingchuan Wang, Siyi Xu, Lei Tang, Si Gong, Jun Rao 2025-08-23 BMC Cancer 0 3
visibility_off Cancer Systems Biology Ravi Salgia, M. Jolly, Prakash Kulkarni, Govindan Rangarajanm 2025-09-01 None 0 57
visibility_off ZNF180 modulates tumor intrinsic immunotherapy resistance in melanoma through driving plasticity Won-Min Song, Sree Karani Kondapuram, Xianxiao Zhou, Shu-hsia Chen, Praveen Agrawal 2025-09-18 bioRxiv 0 6
visibility_off Balanced chromosomal insertions as the mechanism of recurrent familial microstructural abnormalities: detailed analyses using long-read whole-genome sequencing. Hironao Shirai, Keiko Shimojima Yamamoto, Hirokazu Arai, Yukio Sawaishi, Saori Fujita, Yoko Kuriyama, Masaki Miura, Jun Tohyama, Toshiyuki Yamamoto 2025-09-24 Journal of human genetics 0 4
visibility_off High-throughput cytological profiling uncovers genotype-phenotype associations in Mycobacterium tuberculosis clinical isolates. Qingyun Liu, Yue J Liu, Ruiyuan Liu, Peter H. Culviner, Xin Wang, I. D. Wolf, Ken Chen, Yiwang Chen, Yi Xiao, Guiming Zhang, Rongfeng Sun, Shoko Wakabayashi, Nicole C Howard, Mingyu Gan, Eric J. Rubin, Sarah M. Fortune, Junhao Zhu 2025-10-09 mSystems 0 12
visibility_off Impact of Chromosomal Instability and Aneuploidy in Cancer Development Amanda K. Mennie, Brittiny Dhital, Peter Ly 2025-09-30 Annual Review of Cancer Biology 0 3
visibility_off DFFB suppresses interferon to enable cancer persister cell regrowth August F Williams, David A. G. Gervasio, C. Turkal, Anna E. Stuhlfire, Michael X. Wang, B.E. Mauch, Rhea Plawat, Ariel H Nguyen, Michelle H. Paw, Mehrshad Hairani, Cooper P. Lathrop, Sophie H. Harris, Jennifer L. Page, Matthew J Hangauer 2025-08-21 bioRxiv 0 2
visibility_off Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF+ tumor cells and the therapeutic potential of FOS Xiangsong Cheng, Shu Chen, Yilong Fu, Runze Jiang, Yanlong Jing, Bizhu Zhao, Dong Guo, Liangyu Wang, Zi Ye, Yumeng Li, Xianliang Chen 2025-08-27 Frontiers in Immunology 0 2
visibility_off Quantitative functional profiling of ERCC2 mutations deciphers cisplatin sensitivity in bladder cancer J. Börcsök, Diyavarshini Gopaul, Daphne Devesa-Serrano, Clémence Mooser, Nicolas Jonsson, M. Cagiada, D. Stormoen, M. N. Ataya, B. Guercio, H. Kaimakliotis, G. Iyer, Kresten Lindorff-Larsen, L. Dyrskjøt, Kent W. Mouw, Z. Szallasi, C. S. Sørensen 2025-08-15 The Journal of Clinical Investigation 0 43
visibility_off Uncovering the regulatory landscape of early human B cell lymphopoiesis and its implications in the pathogenesis of B-ALL Núria Planell, Xabier Martínez-de-Morentin, Daniel Mouzo, D. Lara-Astiaso, A. Vilas-Zornoza, P. S. Martín-Uriz, D. Alignani, B. Paiva, A. Maillo, Aleksandra Kurowska, Nerea Berastegui, P. García-Olloqui, Arantxa Urdangarin, Peri Noori, A. Ortega-Legarreta, Mikel Hernaez, V. Lagani, N. Kiani, Matthias Merkenschlager, T. Ezponda, J. Martín-Subero, Ricardo N. Ramirez, Jesper N. Tegnér, F. Prósper, D. Gómez-Cabrero 2025-10-10 Science Advances 0 59
visibility_off Abstract B082: Clonal dynamics and molecular mechanisms mediating resistance to RAS inhibition Jayne C McDevitt, Connor J Hennessey, R. V. Velde, Sydney M. Shaffer, Ben Z. Stanger 2025-09-28 Cancer Research 0 5
visibility_off The Underlying Mechanisms and Emerging Strategies to Overcome Resistance in Breast Cancer Krishnaswamy Kannan, Alagarsamy Srinivasan, Aarthi Kannan, Nawab Ali 2025-09-01 Cancers 0 2
visibility_off Abstract B040: Uncovering senescence-driven pathways in diffuse midline glioma progression and treatment resistance Timothy H. Chang, Alexander Nassar, Ria Kedia, Shriya Rangaswamy, Claudia L Kleinman, P. Bandopadhayay 2025-09-25 Cancer Research 0 41
visibility_off Resistance to CDK7 inhibitors directed by acquired mutation of a conserved residue in cancer cells. Chun-Fui Lai, Victoria I. Cushing, Ellen Olden, C. Bevan, R. C. Coombes, Basil J. Greber, L. Buluwela, Simak Ali 2025-09-08 The EMBO journal 0 26
visibility_off Abstract A012: Cancer acquires therapy resistance by converting immune infiltration to exclusion through NK cell-macrophage interactions Chia-Hsin Hsu, Andrew C White 2025-09-24 Cancer Immunology Research 0 1
visibility_off Analysis of Naturally Occurring Somatic Insertions in the Human Genome. Chih-Lin Hsieh, Zarko Manojlovic, Timothy Okitsu, C. Okitsu, Jordan Wlodarczyk, Nick Schillingford, Ramzi Bawab, Yong Hwee Eddie Loh, Michael R. Lieber 2025-09-26 bioRxiv : the preprint server for biology 0 7
visibility_off The reference genome of the human diploid cell line RPE-1 Emilia Volpe, A. Colantoni, Luca Corda, Elena Di Tommaso, Franca Pelliccia, Riccardo Ottalevi, A. Guarracino, Danilo Licastro, Luigi Faino, M. Capulli, G. Formenti, Evelyne Tassone, Simona Giunta 2025-09-12 Nature Communications 0 25
visibility_off Circular RNAs: key regulators of paclitaxel sensitivity and resistance in cancer Zahra Tajik, S. Ghafouri-Fard 2025-08-18 European Journal of Medical Research 0 53
visibility_off Ceramide-induced Endoplasmic Reticulum Stress as a Targetable Vulnerability in Endocrine Therapy-Resistant Breast Cancer Purab Pal, S. Chitkara, Godwin K. Sarpey, Fatimah Alani, Huiping Zhao, Malik Ata, Jun Qu, Rachel Schiff, Debra A. Tonetti, Geoffrey L. Greene, Jonna Frasor, G. E. Atilla‐Gokcumen, Jonathan L. Coloff 2025-08-22 bioRxiv 0 25
visibility_off Lineage plasticity and histological transformation: tumor histology as a spectrum. Xiaoling Li, Eric E. Gardner, Sonia Molina-Pinelo, Clare Wilhelm, Ping Mu, Á. Quintanal-Villalonga 2025-09-30 Cell research 0 17
visibility_off Novel mutations in transducin-like enhancer of split 6 cause infertility in women with embryonic arrest. Jifan Tan, Yue Jiang, Ching Wan, Kehan Zhu, Yan Xu, Yanwen Xu, Jia Huang 2025-09-27 Journal of assisted reproduction and genetics 0 2
visibility_off Diverse short tandem repeat sequences influence gene regulation in human populations Aleksandra Mitina, W. Engchuan, Brett Trost, G. Pellecchia, Stephen W. Scherer, Ryan K C Yuen 2025-09-12 Genome Biology 0 33
visibility_off Patient-specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity. M. Strecker, Keren Zohar, Martin Böttcher, T. Wartmann, H. Freudenstein, Maximilian Doelling, M. Andric, W. Shi, O. Kakhlon, Katrin Hippe, Beatrix Jahnke, D. Mougiakakos, Franziska Baenke, Daniel Stange, R. Croner, M. Linial, U. Kahlert 2025-09-24 Molecular oncology 0 25
visibility_off Toward an understanding of cancer-associated ribosomal protein mutations Mikael S. Lindström 2025-10-03 Tumor Discovery 0 0
visibility_off Single-cell RNA-seq reveals gene expression heterogeneity in NSCLC and its link to the immune microenvironment Jinzhuo Ren, Hua Zhang, Haiyong Wu 2025-09-24 Discover Oncology 0 0
visibility_off Structural variants are enriched in deleterious visible phenotypes in Drosophila. Alejandra Samano, Matthew Musat, Mihir Junaghare, Asad Ahmad, Mehlum Ali, Sebastian Alves, Sreeram Pasupuleti, Jelisha Perera, Omar Saada, Brady Sabido, Trevor Smith, Sophie Walz, Mahul Chakraborty 2025-08-21 bioRxiv : the preprint server for biology 0 12
visibility_off Understanding Tumor Dormancy: from Experimental Models to Mechanisms and Therapeutic Strategies Jaebeom Cho 2025-08-31 Biomolecules & Therapeutics 0 0
visibility_off Second-order allosteric control as a mechanism for compensatory mutations in B-cell translocation gene 2. Nicholas J. Ose, P. Campitelli, Tushar Modi, S. Ozkan 2025-08-25 Protein science : a publication of the Protein Society 0 7
visibility_off Integrative analysis of molecular mechanisms in prostate cancer via single-cell RNA sequencing and weighted gene co-expression network analysis Jing Zhai, Yizhou Wang, Yu Zhang, Wenhui Zhu, Xinyu Xu, Yu Peng, Guanxiong Ding 2025-09-26 Scientific Reports 0 1
visibility_off rRNA paralogs with variations, rRNA-subtypes, affect diverse human phenotypes Daphna Rothschild, Jonathan K. Pritchard, Maria Barna 2025-09-04 medRxiv 0 9
visibility_off New advances in understanding the mechanisms and treatment challenges of ALK-targeted therapy resistance in lung cancer Mengle Long, Shixuan Peng, Qingyang Wen, Zhijian Yin, Xinwen Zhang, Haoyu Tan, Yun Xu, Yongjun Wu 2025-08-25 Cancer Drug Resistance 0 2
visibility_off Integrating single-cell RNA sequencing and artificial intelligence for multitargeted drug design for combating resistance in liver cancer Houhong Wang, Youyuan Yang, Junfeng Zhang, Wenli Chen, Jingyou Dai, Changquan Li, Qing Li 2025-09-02 NPJ Precision Oncology 0 2
visibility_off Replication-associated mechanisms contribute to an increased CpG > TpG mutation burden in mismatch repair-deficient cancers Joseph C Ward, Ignacio Soriano, Steve Thorn, Juan Fernández-Tajes, Kitty Sherwood, Güler Gül, Joost Scheffers, A. Frangou, Ben Kinnersley, Ioannis Kafetzopoulos, Duncan Sproul, Sara Galavotti, C. Palles, Andreas J. Gruber, David N. Church, Ian Tomlinson 2025-08-25 Genome Medicine 0 47
visibility_off Seq2Karyotype (S2K): A Method for in-silico Karyotyping Using Single-Sample Whole-Genome Sequencing Data Limeng Pu, Karol A. Szlachta, Virginia Valentine, Meiling Jin, Sivaraman Natarajan, Robert Greenhalgh, Nadezhda V. Terekhanova, Jian Wang, Daniel K. Putnam, Li Dong, Lingxiang Jiang, Soumya Tumbath, Xiumei Huang, Xiaotu Ma, Thomas Look, Marcin W. Włodarski, Lu Wang, Steven Burden, J. Easton, Xiang Chen, Jinghui Zhang 2025-08-27 bioRxiv 0 67
visibility_off Gene-Expression Programs in Salivary Gland Adenoid Cystic Carcinoma Analyzed Using Single-Cell and Spatial Transcriptomics Ifeoma Ebinumoliseh, Gopikrishnan Bijukumar, Kendall Hoff, K. Brayer, Elaine L. Bearer, Scott A. Ness, Jeremy S. Edwards 2025-09-05 bioRxiv 0 13
visibility_off Resolving structural variations missed by short-read sequencing uncovers their pathogenicity. C. Schluth-Bolard, Laïla El Khattabi, P. Rollat-Farnier, N. Chatron, Marion Beaumont, N. Reynaud, K. Uguen, F. Diguet, A. Labalme, Claire Bardel, T. Mantere, Vérane Bard, Andreea Apetrei, A. Afenjar, F. Amblard, Jeanne Amiel, Sophie Christin-Maître, F. Devillard, M. Fradin, B. Isidor, A. Lokchine, S. Jaillard, R. Olaso, Massimiliano Rossi, S. Valence, J. Deleuze, A. Hoischen, J. Siffroi, D. Sanlaville 2025-08-20 Journal of medical genetics 0 79
visibility_off Identification, functional insights and therapeutic targeting of EMT tumour states. Anqi Dong, Cédric Blanpain 2025-09-25 Nature reviews. Cancer 0 5
visibility_off Thymic epithelial cells amplify epigenetic noise to promote immune tolerance. Noah Gamble, Jason A Caldwell, Joshua McKeever, Caroline Kaiser, Alexandra Bradu, Peyton J. Dooley, Sandy Klemm, William J. Greenleaf, Narutoshi Hibino, Aaron R. Dinner, Andrew S. Koh 2025-08-20 Nature 0 5
visibility_off Identifying Novel Gene Targets in RET-Driven Cancers Using Synthetic Dosage Lethality Models Zahra Simpson-Stairs 2025-08-29 Inquiry@Queen's Undergraduate Research Conference Proceedings 0 0
visibility_off 27Characterization of aberrant alternative splicing landscape in patients with metastatic renal cell carcinoma Benjamin D. Mercier, Ameish Govindarajan, Nathaniel Hansen, Sara Byron, Apurva Hegde, Kristin Leskoske, N. Chawla, Luis Meza, Z. Zengin, R. Barragan-Carrillo, Hedyeh Ebrahimi, Daniela V. Castro, S. Jaime-Casas, M. Zugman, N. Dizman, J. Hsu, A. Chehrazi-Raffle, A. Tripathi, Nicholas J. Salgia, Sumanta Pal, Patrick Pirrotte 2025-10-01 The Oncologist 0 21
visibility_off Allele Level Sequencing of Killer Cell Immunoglobulin‐Like Receptor Genes Using Oxford Nanopore Long Read Sequencing Jonathan Downing, Daniel Abromeit, L. Truong, F. Mobegi, Patricia Martinez, Lloyd J D'Orsogna, D. de Santis 2025-09-01 Hla 0 13
visibility_off Abstract B092: Investigating combination therapies to overcome RAS inhibitor resistance in pancreatic cancer Vasiliki I. Pantazopoulou, Casie S. Kubota, Satoshi Ogawa, Kassidy Curtis, Araceli Herrera Morales, Dannielle D. Engle 2025-09-28 Cancer Research 0 22
visibility_off MODERN INSIGHTS OF DNA FUNCTION AND HEREDITY: A REVIEW OF MOLECULAR GENETICS AND CRISPR GENE Mariam Fatima, Mariam Fatima¹, Muhammad Haseeb, Anwar Tarar¹, Arooba Maryam², Muhammad Azhar, Ud Din³˒⁴, Ifra Muzaffar¹, H.M. Saif, UR Rahman⁵, Rida Sattar⁶ 2025-08-21 Journal of Medical & Health Sciences Review 0 3
visibility_off TCR germline diversity reveals evidence of natural selection on variable and joining alpha chain genes S. Mantena, Ali Akbari, Soumya Raychaudhuri 2025-08-24 bioRxiv 0 12
visibility_off Pan-cancer single-cell and spatial transcriptomics implicate cancer-associated fibroblasts in neutrophil immunosuppressive phenotypic transitions and immunotherapy resistance. Zhiyu Guo, Xujia Li, Lingli Huang, Yue Yan, Mengge Gao, Jinsheng Huang 2025-10-10 Functional & integrative genomics 0 5
visibility_off Longitudinal tissue analysis reveals microenvironmental changes correlate with combined immunotherapy and targeted therapy response in metastatic breast cancer , Jien Wang, Hengyu Li, Zhijun Liu, Z. Tian, Xinying Lv, Jianjian Peng, Chuangui Song, Jieqiong Liu 2025-10-01 Journal for Immunotherapy of Cancer 0 6
visibility_off Exosomal miRNA expression profiling in patients with imatinib resistant Chronic myeloid leukemia: A pilot study R. Navakanitworakul, Pirun Saelue, Tipparat Penglong, P. Molika, Natakorn Nokchan, Natta Tansila, H. Buncherd, Supinya Thanapongpichat, Kanitta Srinoun 2025-08-29 PLOS One 1 11
visibility_off Single-cell profiling uncovers PTPRG-driven stemness in malignant plasma cells and signatures of treatment failure in multiple myeloma Jiewen Tan, Jinman Zhong, Yueping He, Yunman Xu, Chang Chen, Dan Xiong 2025-09-18 Frontiers in Immunology 0 1
visibility_off Abstract A048: Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy Helen S. Mueller 2025-09-25 Cancer Research 0 1
visibility_off TP53 mutations drive therapy resistance via post-mitochondrial caspase blockade Ahmed M Mamdouh, E. Olesinski, Fang Qi Lim, S. Jasdanwala, Yang Mi, Nicole Si, En Lin, Daniel Tan, En Liang, Nishtha Chitkara, L. Hogdal, R. C. Lindsley, A. Letai, Koji Itahana, Shruti Bhatt 2025-08-31 bioRxiv 0 78
visibility_off Abstract A023: Combating ovarian cancer resistance via polyploid cancer cell targeted screening Hsiao-Chun Chen, Yuan Zhang, Yushu Ma, Yu-Chih Chen 2025-09-19 Cancer Research 0 7
visibility_off The Role of LINC02381 in Modulating Cisplatin Resistance in Ovarian Cancer: A Bioinformatics Approach Zeinab Karbalaei Pazoki, B. M. Soltani, Mostafa Hosseini, Shiva Irani 2025-09-26 Iranian Journal of Allergy, Asthma and Immunology 0 0
visibility_off Targeting ORMDL2 in glioblastoma through integrated landscape of high-throughput sequencing and pharmacogenomic analysis Fitria Sari Wulandari, Chih-Yang Wang, Sachin Kumar, Ngoc Phung Ly, Juan Lorell Ngadio, Dahlak Daniel Solomon, Do Thi Minh Xuan, Gabriela Natasha Sutandi, Hung-Yun Lin, Hui-Ru Lin, Yung-Kuo Lee, Hao-Chien Yang, , Ching-Chung Ko 2025-09-27 International Journal of Medical Sciences 0 6
visibility_off Transposable elements in health and disease: Molecular basis and clinical implications Yaqiang Hong, Nian Liu 2025-08-15 Chinese Medical Journal 0 3
visibility_off Pan-ERBB Inhibitors Synergize With KRAS Inhibitors in Rectal Cancer. Jonas Buchloh, M. Spitzner, Hauke Zimmermann, Xin Fang, Constanza Tapia Contreras, Carolin Schneider, Tiago de Oliveria, Stefan Küffer, Michael Linnebacher, Felix Rühlmann, Lena-Christin Conradi, Matthias Wirth, Michael Ghadimi, Marian Grade, Jochen Gaedcke, Günter Schneider 2025-09-16 United European gastroenterology journal 0 22
visibility_off Single-cell and spatial transcriptomics reveal post-translational modifications in osteosarcoma progression and tumor microenvironment Yue Cui, Yue Wu, Dongyu Jiang, Tao Ding 2025-10-09 PLOS One 0 0
visibility_off Induced somatic mutation accumulation during skeletal muscle regeneration reduces muscle strength P. Vrtačnik, Lara G. Merino, Santhilal Subhash, Hafdís T. Helgadóttir, Matthieu Bardin, Fabiana Stefani, Depin Wang, Ping Chen, Irene Franco, Gwladys Revêchon, Maria Eriksson 2025-08-20 Nature Aging 1 27
visibility_off Reprogramming glutamine metabolism enhances BCMA-CART cell fitness and therapeutic efficacy in multiple myeloma. Flor Navarro, Teresa Lozano, Andrea Fuentes-García, Inés Sánchez-Moreno, M. Larrayoz, Pedro Justicia, Beatriz Perucha, Maialen Martinez-Tabar, Rebeca Martinez-Turrillas, N. Casares, Celia Martín-Otal, M. Gorraiz, Erin W. Meermeier, M. Chesi, Douglas Lake, P. L. Bergsagel, Eva Santamaría, M. E. Calleja-Cervantes, Patxi San Martín-Úriz, Lorea Jordana-Urriza, X. Agirre, S. Hervás-Stubbs, J. R. Rodríguez-Madoz, Jose-Al Martinez-Climent, F. Prósper, J.J. Lasarte 2025-09-19 Blood 1 57
visibility_off CHIP ahoy: charting a decade of discovery in clonal hematopoiesis. Casey K. Wong, Alexandra McDonald, M. Buttigieg, M. Rauh 2025-09-04 Haematologica 0 10
visibility_off Suppressing protein damage response to overcome multidrug resistance in cancer therapy Fangyuan Shao, Zongjie Li, Hao Xiao, Yujun Chen, Yuheng Zhang, Ling Li, Yuzhong Peng, Xinyi Li, Yuxing Hou, Bo Li, Xiangpeng Chu, Maoxin Ran, Dongyang Tang, Xi Han, Jiaxin Yao, Cuiting Zhang, Lijian Wang, Haifeng Li, N. Shao, Kai Miao, Xiaoling Xu, Yanxia Shi, Changhua Zhang, Jun Yan, Ying Lin, Chu-Xia Deng 2025-09-30 Cell Discovery 0 25
visibility_off Abstract B129: Tracking genome evolution and chemoresistance in pancreatic cancer A. Lumeau, Molly A Guscott, N. M. Père, Isabel Nichols, Benjamin Werner, Nelson Dusetti, Sarah E. McClelland 2025-09-28 Cancer Research 0 4
visibility_off Carcinogenesis: An Alternative Hypothesis Comparing Mutagenic Versus Metabolic Models A. Alhatem, C. Gagna, Muriel Lambert, Emily Keenan, W. Lambert 2025-09-23 Biology 0 9
visibility_off miRNA-mediated resistance mechanisms in prostate cancer: implications for targeted therapy and metastatic progression. Mostafa M. Mostafa, M. K. A. El-Aziz, D. Ellakwa 2025-08-29 Medical oncology 0 14
visibility_off Pharming: Joint Clonal Tree Reconstruction of Single-Nucleotide Variant and Copy Number Aberration Evolution from Single-Cell DNA Sequencing of Tumors. Leah L. Weber, Anna Hart, Idoia Ochoa, M. El-Kebir 2025-09-15 Journal of computational biology : a journal of computational molecular cell biology 0 19
visibility_off Age-Driven Genetic and Epigenetic Heterogeneity in B-ALL Yoana Veselinova, M. Esteller, Gerardo Ferrer 2025-09-01 International Journal of Molecular Sciences 0 3
visibility_off Phage therapy and its role in cancer treatment and control. H. A. Abd El-Moaty, A. Doghish, Hebatallah Ahmed Mohamed Moustafa, Wagiha S. Elkalla, Ghadir A Sayed, Nourhan H Elshami, S. S. A. Mageed, Osama A Mohammed, Mahmoud A. Elrebehy, Kareem AlFarsi, Amr M. Abdelfatah, Aly M Waseem, Ahmed O Abdulkader, Rabab S. Hamad, Akram N Salah 2025-09-17 Folia microbiologica 0 48
visibility_off Mutational Disruption of TP53: A Structural Approach to Understanding Chemoresistance Ali F. Alsulami 2025-09-01 International Journal of Molecular Sciences 0 7
visibility_off RAD51-mediated homologous recombination is a pro-tumour driver pathway. Bernard S. Lopez 2025-09-24 Oncogene 0 6
visibility_off An in vitro tumor recurrence model based on platinum-resistant colon cancer cells as a research tool for studying cancer cell dormancy A. Morshneva, O. Gnedina, M. Igotti 2025-10-08 PLOS One 0 4
visibility_off Epigenetic synthetic lethality as a cancer therapeutic strategy: synergy of experimental and computational approaches. Maria Farina-Morillas, Laia Ollé-Monràs, Silvana Ce Maas, Isabel de Rojas-P, Miguel F. Segura, Jose A. Seoane 2025-08-25 Epigenomics 0 2
visibility_off Revealing genetic drivers of ovarian cancer and chemoresistance: insights from whole-genome CRISPR-knockout library screens. Tali S. Skipper, Kristie-Ann Dickson, Christopher E. Denes, Matthew A. Waller, Tian Y. Du, G. Neely, N. Bowden, Alen Faiz, Deborah J. Marsh 2025-08-28 Cellular oncology 0 12
visibility_off Abstract B031: Uncovering genetic and regulatory drivers of tumor-specific splicing in pediatric brain tumors Patricia J Sullivan, Ryan J. Corbett, Ammar S. Naqvi, Alexander Sickler, Rebecca S. Kaufman, Bo Zhang, Chuwei Zhong, S. Diskin, J. L. Rokita 2025-09-25 Cancer Research 0 47
visibility_off Single‐Cell Mitochondrial DNA Analysis of Recombinant Chinese Hamster Ovary Cells Reveals Widespread Heteroplasmy Alan Foley, N. Lao, Ciara McGuirk, Colin Clarke, Niall Barron 2025-09-01 Biotechnology Journal 0 15
visibility_off A high-resolution meiotic crossover map from single-nucleus ATAC-seq reveals insights into the recombination landscape in mammals S. Novakovic, Caitlin Harris, Ruijie Liu, Davis J. McCarthy, W. Crismani 2025-09-01 NAR Genomics and Bioinformatics 0 15
visibility_off Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells Alexander Kowar, Jonas P. Becker, Rossella Del Pizzo, Zhiwei Tang, Julien Champagne, Kathrin Wellach, Kiana Samimi, Ariel Galindo-Albarrán, Pierré-René Körner, Jasmine Montenegro Navarro, Andrés Elía, Fiona Megan Tilghman, Hanan Sakeer, M. Mendoza-Parra, Angelika B. Riemer, R. Agami, Fabricio Loayza-Puch 2025-01-09 Nature Communications 0 66
visibility_off Quiescent OXPHOS-high triple-negative breast cancer cells that persist after chemotherapy depend on BCL-XL for survival Slawomir Andrzejewski, Marie Winter, Leandro Encarnacao Garcia, O. Akinrinmade, Francisco Madeira Marques, Emmanouil Zacharioudakis, Anna Skwarska, J. Aguirre-Ghiso, Marina Konopleva, Guangrong Zheng, Susan Fineberg, Daohong Zhou, E. Gavathiotis, Tao Wang, Eugen Dhimolea 2025-08-25 bioRxiv 0 47
visibility_off Systematic decoding of functional enhancer connectomes and risk variants in human glioma. Jinfang Bi, Weipeng Mo, Man Liu, Yingjie Song, Qian Xiao, Sibo Fan, Wenbin Wang, Tengfei Shi, Yaoqiang Zheng, Jie Lian, Rong Liu, Bohan Chen, Xiaofeng Huang, Peng Li, Zhongfang Zhao, Jiandang Shi, Lei Zhang, Guangsong Su, Nu Zhang, Wange Lu 2025-08-19 Nature cell biology 1 14
visibility_off Abstract A043: Combination Therapeutic Targeting of Chromatin Complexes in Neuroblastoma Melinda Soeung, Kenneth Ross, L. Merickel, S. Salhotra, A. Taillon, A. Basanthakumar, K. Stegmaier 2025-09-25 Cancer Research 0 1
visibility_off The roles of NHEJ and TLS pathways in genomic alterations and phenotypic evolution in the yeast Yarrowia lipolytica Cen Yan, Ye-Ke Wang, Yuan-Ru Xiong, Xin-Qiu Zhou, Yuan-Chun Fang, Ruo-Tian Nie, Cunqi Ye, Ke Zhang, Dao-Qiong Zheng 2025-08-15 Applied Microbiology and Biotechnology 0 6
visibility_off FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia Wenlong Li, Yutao Zhao, Dong Wu, Zhenhua Chen, Y. Qing, Fan Yang, Fei Ji, Linda Zhang, Lillian Sau, Jianjun Chen, Chuan He 2025-08-15 Science Advances 2 15
visibility_off Transcriptional Rewiring of BET Inhibitor Treated Ewing Sarcoma Cells Augments their Dependency on Focal Adhesion Kinase. Shireen S Ganapathi, Emma D. Wrenn, Nicolas M Garcia, Neerja Katiyar, Stephanie I. Walter, Aya Miyaki, Jonah R. Valenti, Yuqi Kang, Marina Chan, Taranjit S. Gujral, Elizabeth R. Lawlor 2025-09-06 bioRxiv : the preprint server for biology 0 22
visibility_off Single-cell RNA sequencing identifies CD8Teff cell activation as a predictive biomarker in triple-negative breast cancer immunotherapy L. Mao, Zebang Zhang, Yongjian Chen, Qing Peng, Zhenjun Huang, Wenhao Ouyang, D. Zeng, W. Ren, Zifan He, Tang Li, Zehua Wang, Ruichong Lin, Jianli Zhao, Jiannan Wu, Herui Yao, Yunfang Yu 2025-09-19 Molecular Biomedicine 0 17
visibility_off The Role of PI3K/AKT Signalling Pathway in Cancer Stem Cells: Emerging Therapeutic Targets and Resistance Mechanisms Komal Arooj, Hassan Imam, Zarlish Attique, Zoha Naeem, Ali Ahmad, Hafiz Muhammad Faraz Azhar, Fariha Javaid, Zeenat Nawaz 2025-09-30 Futuristic Biotechnology 0 2
visibility_off Resistance Mutations in CLL: Genetic Mechanisms Shaping the Future of Targeted Therapy Samantha Sekeres, Erica N. Lamkin, Eduardo Bravo, Allison Cool, Justin Taylor 2025-09-01 Genes 0 8
visibility_off DNA repair helicases: from mechanistic understanding to therapeutic implications Vijay Menon, Susan E. Gueble 2025-10-07 NAR Cancer 0 3
visibility_off Plasticity of Epigenomic and Transcriptomic Aging Reveals Common Targets for Reprogramming by Environmental Exposures Cheryl Walker, Sandra L. Grimm, Rahul K. Jangid, Marisa S. Bartolomei, Dana C. Dolinoy, D. Aylor, Gokhan Mutlu, Shyam Biswal, Bo A Zhang, Robert Hamanaka, Justin A. Colacino, Maureen Sartor, Laurie Svoboda, Ting Wang, Cristian Coarfa 2025-09-19 Research Square 0 10
visibility_off Molecular mechanisms of proliferative senescence and genomic instability in Werner syndrome and the WRN gene network. Martin Poot 2025-09-19 Cytogenetic and genome research 0 4
visibility_off A Mammalian Genomic Signature Shaped by Single Nucleotide Variants Controlling Transcriptome Integrity and Diversity. Jian Yang, Samuel Ogunsola, Jason Wong, Aydan Wang, R. Joehanes, Daniel Levy, Shalini Sharma, Chunyu Liu, Jiuyong Xie 2025-09-11 bioRxiv : the preprint server for biology 0 48
visibility_off Computational Strategies in Tumor Phylogenetics: Evaluating Multi-Modal Integration and Methodological Trade-Offs Across Study Designs Chenghan Jiang, Zhe Wang, Ruoyu Wang, Shanshan Liang, Shuai Tao 2025-10-01 Bioinformatics Advances 0 2
visibility_off Cross-species analysis identifies genotype-driven vulnerabilities in lung adenocarcinoma. Angeliki Karatza, Maayan Pour, Jaylen M Powell, Yuan Hao, Dimitris Nasias, Yi Jer Tan, Alfonso Lopez, M. Ciampricotti, Chengwei Peng, Álvaro Quintanal Villalonga, Yeuan Ting Lee, Ruveyda Ayasun, Muhammad Elnaggar, Priyanka Sahu, Igor Dolgalev, Hai Hu, Luis Chiriboga, Cynthia Loomis, Daniel Andrussier, Magdalena A Ploszaj, A. Tsirigos, Peter Meyn, Fred P. Davis, Nicolas Stransky, Gromoslaw A. Smolen, John T. Poirier, Jonathan So, Mark Philips, Harvey I. Pass, Dafna Bar Sagi, Itai Yanai, Kwok-Kin Wong 2025-08-27 bioRxiv : the preprint server for biology 0 70
visibility_off Abstract A046: Functional genetic screen of TP53 mutants reveals APR-246 sensitivity is mediated by p53 independent effects Anais Saunders, Caili Tong, A. Karnezis, G. Leiserowitz, Jeremy Chien 2025-09-19 Cancer Research 0 51
visibility_off A Universal Duplex Sequencing Approach for Accurate Detection of Somatic Mutations Shuvro P. Nandi, Yuhe Cheng, Shams Al-azzam, Safa Saeed, Audrey Kristin, Nadia Sunico, Isabella Stuewe, Zichen Jiang, Luka Culibrk, Maria Zhivagui, Xiaoxu Yang, Rachel Wise, Foster C. Jacobs, Bérénice Chavanel, M. Korenjak, Mia Petljak, S. Balbo, Laurie G Hudson, Ke Jian Liu, Jiri Zavadil, Joseph G Gleeson, Ludmil B. Alexandrov 2025-09-16 bioRxiv 0 74
visibility_off Integrative single-cell and bulk transcriptomic analysis reveals the landscape of T cell mitotic catastrophe associated genes in esophageal squamous cell carcinoma Shuang Li, Zheng Tao, Nan Wang, Yazhou Liu, Kai Xie, Haitao Ma 2025-08-29 Human Genomics 0 3
visibility_off Identification of potential hub genes and molecular mechanisms in breast cancer microenvironment: A comprehensive transcriptomics approach MS Abdullah Al Noman, MS a Abdullah Al Saba, MS a Mohammad Sayem, PhD Tahirah Yasmin, PhD A. H. M. Nurun Nabi, A. N. Nabi 2025-08-29 Medicine 0 2
visibility_off CTNNA3 and MBP Mediate Treatment Resistance Through Tumor Microenvironment Remodeling in Recurrent Glioblastoma Wenna Mao 2025-09-24 Theoretical and Natural Science 0 0
visibility_off Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer Colin Sheehan, Lyndon Hu, Guillaume Cognet, Grace Croley, Thao Trang Nguyen, Anika Thomas-Toth, Darby Agovino, Patrick B. Jonker, Mumina Sadullozoda, Leah M. Ziolkowski, James K. Martin, Alica K Beutel, Ranya Dano, Mohammed A. Khan, Christopher J Halbrook, Kay F. Macleod, Christopher R. Weber, James L LaBelle, Alexander Muir 2025-09-08 bioRxiv 0 11
visibility_off Clustering of lymphoid neoplasms by cell of origin, somatic mutation and drug usage profiles: a multi-trait genome-wide association study Murat Güler, F. Canzian 2025-08-29 Blood Cancer Journal 0 82
visibility_off LEF1 confers resistance to DNA-damaging chemotherapies through upregulation of PARP1 and NUMA1 in ovarian cancer. Lin Huang, Mengna Zhu, Mengqing Chen, F. Ying, Qiulei Wu, Pan Liu, Wenhan Li, Guoqing Li, Yuewen Gao, Shuyan Yi, Wenwen Wang, Yiping Wen, Si Sun, Jing Cai, Man Xiao 2025-09-10 Oncogene 0 6
visibility_off Deciphering the Impact of Temperature on Pleiotropic Consequences of RNA Polymerase Mutations D. Ozbilek, Jake K. Soley, Danna R. Gifford, Christopher G Knight, Simon C Lovell, M. Lagator 2025-09-16 Molecular Biology and Evolution 0 15
visibility_off Sensitization of cancer cells to DNA-damaging agents by expression of the REV1 C-terminal domain: Implications for chemotherapy. Ke Bian, Charley Gruber, Emine Byers, Paul Leclerc, Michael T. Hemann, Graham C. Walker 2025-09-10 Proceedings of the National Academy of Sciences of the United States of America 0 10
visibility_off KLF4 in cancer chemoresistance: molecular mechanisms and therapeutic implications Suresh Singh Yadav, Punita Kalia, Navneet Kaur, Sourav Sharma, Shambhavi Thakur, Soni Kumari, R. R. Nair 2025-09-22 Discover Oncology 0 1
visibility_off Abstract A040-PR008: Characterization of cytotoxic cell abundance and genetic variants in immune related genes in pediatric acute lymphoblastic leukemia patients Ignacio Gomez Mercado, Daniel Avendaño, Sabrina Ledesma Bazan, P. Sanchis, M. C. Riccheri, G. Gueron, J. Cotignola, Maria Sol Ruiz 2025-09-25 Cancer Research 0 17
visibility_off The cGAS-STING pathway is a master regulator of OCT4 expression in persistent sarcoma cells and enhances cellular immunotherapy with NK and CIK lymphocytes Giorgia Giordano, A. Merlini, F. Capozzi, Giulio Ferrero, Cristina Tucciarello, Shahab Majidi, Simona Comparato, G. Mesiano, Elisabetta Liuzzi, F. Galvagno, Annamaria Massa, Silvia Brusco, V. Leuci, Chiara Riganti, S. Cutrupi, Michele De Bortoli, Lorenzo D’Ambrosio, Dario Sangiolo, G. Grignani, Y. Pignochino 2025-09-23 Cancer Immunology, Immunotherapy : CII 0 53
visibility_off Decoding immune low-response states in ovarian cancer: insights from single-cell and spatial transcriptomics for precision immunotherapy Yalan Yan, Jiaan Lu, Huanyu Luo, Zizhang Wang, Ke Xu, Lexin Wang, Qin Wang 2025-09-19 Frontiers in Immunology 0 6
visibility_off Cancer subclone detection based on DNA copy number in single-cell and spatial omic sequencing data. Chi-Yun Wu, Jiazhen Rong, A. Sathe, Paul R Hess, Billy T Lau, Susan M. Grimes, Sijia Huang, Hanlee P. Ji, Nancy R. Zhang 2025-09-01 Nature methods 1 18
visibility_off Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High‐Risk Diffuse Large B Cell Lymphoma Sara Ovejero, Julie Devin, Laura Alibert, Camille Soun, Yea-Lih Lin, Laure Dutrieux, M. Abouladze, Elvira Garcia de Paco, Ouissem Karmous Gadacha, A. Constantinou, Guillaume Cartron, C. Herbaux, O. Elemento, Philippe Pasero, Sandrine Roulland, J. Moreaux, C. Bret 2025-08-23 Hematological Oncology 0 26
visibility_off Uncovering Rare Structural Chromosomal Rearrangements: Insights from Molecular Cytogenetics M. Czakó, A. Szabó, Á. Till, Anna Zsigmond, K. Hadzsiev 2025-09-01 International Journal of Molecular Sciences 0 17
visibility_off UNDERSTANDING PATTERNS OF CO-DELETION CDKN2A/B DELETED GBM TO SUPPORT A SYNTHETIC LETHALITY APPROACH TO TREATMENT Tanishi Moitra, Michael Castro, Matt Williams 2025-09-01 Neuro-Oncology 0 0
visibility_off Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices Thomas M. DeAngelo, Utsarga Adhikary, Kyle J. Korshavn, H. Seo, Clara R. Brotzen-Smith, Christina M Camara, S. Dhe-Paganon, Gregory H. Bird, T. Wales, L. Walensky 2025-09-29 Nature Communications 0 59
visibility_off Abstract B014: Effects of chronic histone deacetylase inhibitor treatment on Ewing sarcoma cells highlight Ret as a potential therapeutic target Hsin-Ching Lin, Erica Raj, L. Sánchez-González, Aisling Byrne, Shin-Heng Chiou, Arnold B. Rabson 2025-09-25 Cancer Research 0 5
visibility_off Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis Matthew A. McLoughlin, Sruthi Cheloor Kovilakam, William G. Dunn, Muxin Gu, Jake Tobin, Y. Pershad, N. Williams, Daniel Leongamornlert, K. Dawson, Laura Bond, Ludovica Marando, Sean Wen, Rachael Wilson, Giampiero Valenzano, Vasiliki Symeonidou, Justyna Rak, Aristi Damaskou, M. Gozdecka, Xiaoxuan Liu, Clea Bárcena, J. Nomdedeu, Paul Costeas, Ioannis D. Dimitriou, E. Fiorillo, V. Orrù, José Guilherme de Almeida, Thomas McKerrell, Matthew Cullen, I. Mohorianu, T. Foukaneli, Alan J. Warren, Chi Wong, G. Follows, A. Godfrey, Emma J Gudgin, Francesco Cucca, Eoin McKinney, E. J. Baxter, M. Gerstung, J. Mitchell, D. Wiseman, Alexander G. Bick, M. Fabre, Pedro M Quiros, J. Nangalia, Siddhartha Kar, George S. Vassiliou 2025-08-28 Nature Genetics 0 59
visibility_off Inheritable cell-states shape drug-persister correlations and population dynamics in cancer cells Anton Iyer, Adrián E. Granada, Shaon Chakrabarti 2024-11-03 PLOS Computational Biology 0 14
visibility_off FOXA2 and NKX2-1 Orchestrate Neuroendocrine Lineage Plasticity in Prostate Cancer Ka-wing Fong 2025-10-01 Serican Journal of Medicine 0 0
visibility_off Phenotypic variations in glioma stem cells: regulatory mechanisms and implications for therapeutic strategies Guofeng Tian, Yifu Song, Yaochuan Zhang, Liang Kan, Ana Hou, Sheng Han 2025-09-02 Journal of Translational Medicine 0 7
visibility_off NEK9-mediated Wnt signalling repressor TLE3 rewires Docetaxel resistance in cancer cells by inducing pyroptosis. S. Ansari, Sibasish Mohanty, P. Mohapatra, Sudeshna Datta, Mamuni Swain, Rachna Rath, D. Muduly, Saroj K D Majumdar, R. Swain, Sunil K Raghav, Rupesh Dash 2025-09-09 British journal of cancer 0 14
visibility_off mTOR activity and metabolic reprogramming of CD8+ T cells is impaired under hypoxia and within the multiple myeloma bone marrow. Taylor Fulton-Ward, N. Gudgeon, Isaac Thirlwell, E. Bishop, Bryan Marzullo, Hannah Giles, Graham McIlroy, Paul Ferguson, B. Kishore, Kate Rogers, Nuri Nuri Alfasi, Timothy Wong, Satnam Aytain, Daniel A. Tennant, G. Pratt, Sarah Dimeloe 2025-09-12 Blood advances 0 6
visibility_off Dual Targeting of Smoothened, a Key Regulator in the Hedgehog Pathway, and BCR-ABL1 Effectively Eradicates Drug-Insensitive Stem/Progenitor Cells in Chronic Myeloid Leukemia Kelly A. Turner, Min Chen, K. Rothe, Donna L. Forrest, Xiaoyan Jiang 2025-10-09 Cells 0 12
visibility_off Determinants of de novo mutations in extended pedigrees of 43 dog breeds Shao-Jie Zhang, Jilong Ma, Meritxell Riera, S. Besenbacher, J. Niskanen, Noora Salokorpi, S. Hundi, M. Hytönen, Tong Zhou, Gui-Mei Li, E. Ostrander, M. Schierup, H. Lohi, Guo-Dong Wang 2025-09-25 Genome Biology 0 60
visibility_off The UAE Genome Program: Unique Genetic Insights from 43,608 Individuals M. M. Mousa, M. M. Olbrich, I. I. Wohlers, A. A. Al aamri, A. H. Alsuwaidi, N. A. Marzouka, H. H. Alnaqbi, M. Alameri, D. D. Ruta, J. J. Alazazi, T. T. Magalhaes, J. J. Mafofo, J. J. Quilez, M. M. Allam, M. S. Mohamad, N. N. Drou, Y. Y. Idaghdour, R. R. Hamoudi, G. G. Tay, S. S. Ibrahim, F. F. Alkaabi, A. A. Al Mannaei, H. H. Alsafar 2025-09-14 None 0 0
visibility_off Single Nucleotide Polymorphisms Reveal Tumor SizeDependent Mutation Patterns in Breast Cancer Hongyu Gao Hongyu Gao 2025-09-01 Journal of Medical and Dental Science Research 0 0
visibility_off Autosomal Allelic Inactivation: Variable Replication and Dosage Sensitivity Michael B. Heskett, Athanasios E. Vouzas, Brian Johnstone, Krister P Freese, Phillip A. Yates, P. F. Copenhaver, Paul T. Spellman, David M. Gilbert, Mathew J. Thayer 2025-08-18 bioRxiv 0 22
visibility_off PRMT5 genetic interactions with DNA double strand break repair genes Hunter J. Bliss, Juliana Tron, Wesley Bush, Renee A. Bouley, Ruben C. Petreaca 2025-10-09 PLOS One 0 8
visibility_off Genome-wide Genetic Mutations Accumulated in Pigs Genome-edited for Xenotransplantation and Their Filial Generation. X. Huo, Xianhui Sun, Xiangyang Xing, Jing Lu, Jingjing Zhang, Yanyan Jiang, Xiao Zhu, Changlong Li, Jianyi Lv, Meng Guo, Lixue Cao, Xin Liu, Zhenwen Chen, Dengke Pan, Shunmin He, Chen Zhang, Xiaoyan Du 2025-08-20 Genomics, proteomics & bioinformatics 0 14
visibility_off Adaptive genetics reveals constraints on protein structure/function by evolving E. coli under constant nutrient limitation Katja Schwartz, M. Kinnersley, Charles Ross Lindsey, Gavin Sherlock, Frank Rosenzweig 2025-08-20 BMC Biology 0 13
visibility_off Targeting p53-MDM2 pathway with novel triazole-oxazole hybrids: a fragment-based drug discovery approach for next-generation cancer therapies. Apurva Prajapati, Hitesh Patel 2025-09-23 Molecular diversity 0 2
visibility_off Abstract A106: Tracing the immune landscape: Temporal and spatial remodeling during pancreatic cancer progression Atul Verma, Doreen Klingler, Linda Bergmayr, T. V. Inamdar, Jonas Rosendahl, Michael Böttcher, Stefan Hüttelmaier, Patrick Michl, Philipp Jurmeister, Sebastian Krug 2025-09-28 Cancer Research 0 4
visibility_off Programmed Cell Death in Cancer Yuang Wei, William Hankey, Dongliang Xu, Fuwen Yuan 2025-08-31 MedComm 1 4
visibility_off Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer Xiucheng Jiang, Lan Shi, Mei Zhao, Cui Chen, Tao Tang, Simeng Ji, Bingbing Lv, Lihua Jia, Shuhan Duan, Jinyue Ma, Jiyu Pang, Bo Mu, Yongsheng Zhao, Junbao Yang 2025-09-22 Frontiers in Genetics 0 5
visibility_off Investigation of lncRNA expression in newly diagnosed multiple myeloma reveals a LINC01432-CELF2 axis as an inhibitor of apoptosis Richa Mishra, Prasanth Thunuguntla, Dhanusha Duraiyan, Alani Perkin, Katelyn Bagwill, Savannah Gonzales, Catheryn Sizemore, Vanessa Brizuela, Jaiyana King, Steve Daly, Yoon Jae Chang, Mahdote Abebe, Yash Rajana, Kelly Wichmann, Christ Enyan, Shruthi Rangineni, M. Fiala, J. Fortier, R. Jayasinghe, Mark Schroeder, Li Ding, Ravi Vij, John DiPersio, Jessica M. Silva-Fisher 2025-10-06 Oncogenesis 0 28
visibility_off Comprehensive Mutational Landscape of Yeast Mutator Strains Reveals the Genetic Basis of Mutational Signatures in Cancer. Lei Liu, Danyang Sun, Haoxuan Liu 2025-10-06 Molecular biology and evolution 0 1
visibility_off Single-cell RNA sequencing analysis reveals the heterogeneity and effect of TAMs in colorectal cancer. Chengang Wang, Ying Qian, Mingsheng Zhang 2025-08-20 Biochemistry and cell biology = Biochimie et biologie cellulaire 1 1
visibility_off Temporal Clonal Tracing and Functional Perturbation Reveal Niche-Adaptive and Tumor-Intrinsic IFNγ Dependencies Driving Ovarian Cancer Metastasis Emilija Aleksandrovic, Shaneann Fross, Samantha M. Golomb, Xiyu Liu, Zhuo Zhao, Nikitha M. Das, T. Reese, Wei Ma, Jacqueline Lopez, M. S. Stack, Min Zhao, Siyuan Zhang 2025-08-17 bioRxiv 0 5
visibility_off Single-cell genetics identifies cell type-specific causal mechanisms in complex traits and diseases A. Henry, A. Senabouth, R. Tyebally, B. Bowen, P. C. Allen, E. Spenceley, E. Sagi-Zsigmond, A. Cuomo, J. Fan, H. L. Huang, H. Tanudisastro, A. Xue, K. M. de Lange, G. Figtree, A. W. Hewitt, D. G. MacArthur, J. E. Powell 2025-08-29 None 0 16
visibility_off Pathogenic variants in MAEA disrupt DNA replication fork stability and are associated with developmental abnormalities in humans Elham Zeinali, Fatemeh Mashayekhi, Rabih Abou Farraj, Talah Hasanni, Marie-christine Caron, Yan Coulombe, A. Fitieh, J. N. M. Glover, Jean-Yves Masson, Ismail Hassan Ismail 2025-08-29 Science Advances 0 26
visibility_off Deciphering Cell Fate and Clonal Dynamics via Integrative Single-Cell Lineage Modeling Nancy R Zhang, Yuntian Fu, D. Mathew, Mingshuang Wang, Xinyi E. Chen, Kevin Z Lin, Dylan Schaff, Sydney M Shaffer, Drew Pardoll, Christina Jackson 2025-09-24 Research Square 0 33
visibility_off Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancer Carmelo Cerra, Madeleine R. C. Tancock, N. Thio, Ada Koo, AnnRann Wong, Karla J Cowley, Swati Varshney, Madelynne O. Willis, Kaylene Simpson, D. Bowtell, E. Sanij, Elizabeth L Christie, Richard B. Pearson, Jian Kang, Keefe T. Chan 2025-09-25 Cell Death Discovery 0 32
visibility_off The Transcriptional Landscape of Developing Human Trisomy 21 Lungs. S. Bhattacharya, A. Frauenpreis, C. Cherry, Gail Deutsch, I. Glass, Thomas J. Mariani, Denise Al Alam, Soula Danopoulos 2025-09-25 American journal of respiratory cell and molecular biology 0 29
visibility_off Abstract A025: Molecular signature of cisplatin resistance in ovarian cancer identifies therapeutic opportunities for re-sensitization Mahmoud Mansour, Sabrina Van Ginkel, M. Alata, Ibrahim Bani, Isra Elhussin 2025-09-19 Cancer Research 0 10
visibility_off RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids Beverly A. Teicher, T. Dexheimer, Thomas Silvers, N. Coussens, Eric M Jones, Steven D. Gore, Mark W. Kunkel, James H. Doroshow 2025-09-12 Cancer Chemotherapy and Pharmacology 0 35
visibility_off Context-dependent rewiring of dual-function proteins in cancer: a sequential strategy to restore apoptosis Leon Strzadala 2025-10-07 Frontiers in Oncology 0 0
visibility_off The dual role of whole-genome duplication: biological mechanisms, functional consequences, and detection advances. Yawei Song, Jiajie Yang, Shuheng Wu, Wei Wu 2025-09-01 Acta biochimica et biophysica Sinica 0 4
visibility_off Mutagenesis: Insights from Single-Cell, Real-Time Approaches. Marina Elez, Chiara Enrico Bena, Lydia Robert 2025-09-16 Annual review of microbiology 0 8
visibility_off Divergent Clonal Evolution and Early Dissemination Promote Genetic Heterogeneity of Metastases in Castration Resistant Prostate Cancer. Noshad Hosseini, R. Mannan, Ryan J. Rebernick, Fengyun Su, Rui Wang, Xuhong Cao, Ana Lako, Dattatreya Mellacheruvu, Jing Hu, J. Alumkal, Zachery R. Reichert, Rohit Malik, Rohit Mehra, A. Chinnaiyan, M. Cieslik 2025-08-18 Cancer research 0 169
visibility_off Mechanisms and genomic implications of break-induced replication. Adel Atari, Haoyang Jiang, Roger A. Greenberg 2025-08-22 Nature structural & molecular biology 0 5
visibility_off Deciphering Cell Fate and Clonal Dynamics via Integrative Single-Cell Lineage Modeling Yuntian Fu, D. Mathew, Mingshuang Wang, Xinyi E. Chen, Kevin Z Lin, Dylan Schaff, Sydney M Shaffer, Drew M Pardoll, Christina Jackson, Nancy R Zhang 2025-09-04 bioRxiv 0 33
visibility_off Integrative Gene-Centric Analysis of Breast Cancer: High-Confidence Germline Predisposition Genes from Population-Scale Cohorts R. Zucker, S. Schreiber, A. Stern, M. Linial 2025-09-12 None 0 2
visibility_off CRISPR/Cas9 mediated ENT2 gene knockout altered purine catabolic pathway and induced apoptosis in colorectal cell lines Safaa M Naes, S. Ab-Rahim, M. Mazlan, S. Syafruddin, M. A. Mohtar, Asmaa Y Abuhamad, Amirah Abdul Rahman 2025-08-18 PLOS One 0 19
visibility_off MAPK and mTORC1 signaling converge to drive cyclin D1 protein production to enable cell cycle reentry in melanoma persister cells. Varuna Nangia, Humza M. Ashraf, Nasreen Marikar, Victor J. Passanisi, Christopher R Ill, Sabrina L Spencer 2025-09-02 Science signaling 0 10
visibility_off P05.18.B TELOMERE DYSFUNCTION AND FUSIONS IN GLIOBLASTOMA - DEFINING PROGNOSIS AND GENOME INSTABILITY H. Bhatt, K. Norris, K. Cleal, M. Hodgson, C. Herbert, W. Gray, K. Kurian, D. Baird 2025-10-01 Neuro-Oncology 0 9
visibility_off The neural crest-associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy. Nina Wang, Qian Sun, Daniel Novák, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, V. Umansky, Jochen Utikal 2025-10-03 Molecular oncology 0 58
visibility_off Revisiting Clonal Evolution Through the Light of Retrotransposons. Anaïs Lamoureux, Emilie Elvira-Matelot, Françoise Porteu, L. Laplane 2025-10-09 BioEssays : news and reviews in molecular, cellular and developmental biology 0 16
visibility_off Cancer histone mutations impact protein binding and DNA repair with possible links to genomic instability Daniel Espiritu, Yiru Sheng, Yunhui Peng, Daria Ostroverkhova, Shuxiang Li, David Landsman, Maria J Aristizabal, Anna R. Panchenko 2025-09-05 Nucleic Acids Research 0 3
visibility_off DNA Methylation at a Single Locus of Human Genome Accurately Recapitulates Episignature of CREBBP-Related Rubinstein–Taybi Syndrome Olga A. Zemlianaia, A. Kalinkin, A. Tanas, Anna V. Efremova, I. Volodin, O. Ismagilova, Anton S. Smirnov, D. Zaletaev, Marina V Nemtsova, S. Kutsev, V. Strelnikov 2025-09-01 International Journal of Molecular Sciences 0 10
visibility_off Transcriptome Analysis Identifies Functional and Prognostic Hypoxia-Associated Genes in Multiple Myeloma. Lijia Hou, Jing Zhang, Q. Ran, Zhongjun Li, Maoshan Chen 2025-09-26 International journal of laboratory hematology 0 16
visibility_off An integrated enzymatic and computational pipeline for quantifying off-target base-editing Alexander G. McFarland, Soon-Keat Ooi, Davin Tafuri, Elahe Kamali, Natalie Cooper, Emma J Cook, Shantan Reddy, Danuta Jarocha, Nils Wellhausen, Saar Gill, A. Roche, J. Fraietta, Frederic D. Bushman, Friederike Herbst 2025-08-26 bioRxiv 0 41
visibility_off L1 insertion intermediates recombine with one another or with DNA breaks to form genome rearrangements Carlos Mendez-Dorantes, Jupiter C. Kalinowski, Cheuk-Ting Law, Phillip Schofield, Aidan Burn, Kathleen H. Burns 2025-09-18 bioRxiv 0 20
visibility_off Characterizing intra- and inter-tumor heterogeneity in Ovarian high-grade serous carcinoma subtypes using single-cell and spatial transcriptomics Weishan Li, Laurie Grieshober, Jason Gertz, Adriana Ivich, J. Doherty, Casey S. Greene, SC Hicks 2025-09-15 bioRxiv 0 10
visibility_off Small non-coding RNAs: key regulatory factors and potential therapeutic targets in tumor immunity Zihan Liu, Haotian Dong, Chengyuan Ye, Jianing Yan, Min Miao, Y. Shao 2025-09-11 Frontiers in Immunology 0 23
visibility_off Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks Ching-Huang Ho, Maxwell A. Dippel, Meghan S. McQuade, LeAnn P. Nguyen, Arpit Mishra, Stephan Pribitzer, Samantha Hardy, Harshpreet Chandok, Florence M. Chardon, Troy A. McDiarmid, Hannah A. DeBerg, Jane H. Buckner, Jay Shendure, Carl G. de Boer, Michael H. Guo, Ryan Tewhey, John P. Ray 2025-09-18 Nature Genetics 0 16
visibility_off Abstract PR015: Tumor-derived IL-4 links chemotherapy to immunotherapy resistance in ovarian cancer Gurkan Mullaoglu, Hunter T. Potak, Paula Guerrero Gonzalez, Gardner Davlin, Joshua Leinwand, Dmitriy Zamarin, Brian D. Brown, Alessia Baccarini 2025-09-19 Cancer Research 0 20
visibility_off Single-cell transcriptomic analyses provide insights into SPP1+ TAM-mediated immune suppression and CD8+ T cell dysfunction in lung cancer Rahma Taher Almgrami, Tengyue Zhang, Qitai Zhao, Mingming You, Jinyan Liu, Yi Zhang 2025-09-29 Cancer Immunology, Immunotherapy : CII 0 16
visibility_off Collateral mutagenesis funnels multiple sources of DNA damage into a ubiquitous mutational signature Natanael Spisak, Marc de Manuel, Molly Przeworski 2025-09-01 bioRxiv 0 6
visibility_off An overview of mechanisms, biomarkers, and treatment strategies for acquired anti-EGFR resistance in RAS wild-type colorectal cancer Chenxiang Ding, Ruoyu Yao, Yong Wang, Hongjie Liu, Chunyan Li, Hua Xie 2025-09-29 Frontiers in Pharmacology 0 1
visibility_off Abstract IA03: Therapeutic modulation of nucleic acids-induced immune activation Sandra Demaria 2025-09-24 Cancer Immunology Research 0 2
visibility_off Abstract A037: POLQ inhibitors induce replication stress and apoptosis in high-grade serous ovarian cancer: Functional and genomic biomarkers of response Aleksandra Kruglikov 2025-09-19 Cancer Research 0 0
visibility_off Combining Molecular Dynamics and Machine Learning to Predict Drug Resistance Causing Variants of BRAF in Colorectal Cancer Longsheng Xie, Christopher Lockhart, Dmitri K Klimov, M. S. Jafri 2025-08-30 Molecules 0 11
visibility_off Genetic regulation of cell type-specific chromatin accessibility shapes immune function and disease risk A. Xue, J. Fan, O. A. Dong, H. L. Huang, P. C. Allen, E. Spenceley, E. Sagi-Zsigmond, B. Bowen, A. Cuomo, A. Henry, H. Tanudisastro, Z. Qiao, L. Chen, E. Ben-David, K. Farh, D. Neavin, A. S. Lee, A. Senabouth, C. Bartie, R. A. McCloy, V. Chin, K. M. de Lange, G. Figtree, A. W. Hewitt, D. G. MacArthur, J. E. Powell 2025-08-29 None 0 16
visibility_off The RNA-Binding Protein RBMX Mediates the Immunosuppressive Microenvironment of Osteosarcoma by Regulating CD8+T Cells Yu Qiu, Chao Pu, Chengguang Wang, Zhengxue Quan 2025-09-01 Cancers 0 0
visibility_off Abstract IA022: BRCA mutations and protein products in cancer Neil Johnson 2025-09-19 Cancer Research 0 0
visibility_off Functional genetic screens reveal key pathways instructing the molecular phenotypes of tumor-associated macrophages. Youxue Lu, Ce Luo, Lanxiang Huang, Genyi Wu, Lihan Zhong, Jieyu Chu, Fubing Wang, Zexian Zeng, Deng Pan 2025-09-04 Cancer immunology research 0 11
visibility_off Abstract C077: Germline pathogenic variant profiling of DNA double-strand break repair pathways in populations with African and European genetic ancestry Musinu Zakari, Egbenoma A. Aigboeghian, Khadijah A. Mitchell 2025-09-18 Cancer Epidemiology, Biomarkers & Prevention 0 4
visibility_off Somatic mutation and selection at population scale. A. Lawson, Federico Abascal, Pantelis A. Nicola, Stefanie V. Lensing, A. Roberts, Georgios Kalantzis, Adrian Baez-Ortega, Natalia Brzozowska, J. E. El-sayed Moustafa, Dovile Vaitkute, Belma Jakupovic, A. Nessa, Sam Wadge, M. F. Österdahl, Anna L. Paterson, Doris M. Rassl, R. Alcantara, L. O’Neill, S. Widaa, Siobhan Austin-Guest, Matthew D. C. Neville, Moritz J Przybilla, Wei Cheng, M. Morra, Lucy Sykes, Matthew Mayho, Nicole Müller-Sienerth, N. Williams, Diana Alexander, Luke M. R. Harvey, Thomas Clarke, Alex Byrne, Jamie R Blundell, Matthew D Young, Krishnaa T. Mahbubani, K. Saeb-Parsy, Hilary C. Martin, Michael R Stratton, P. J. Campbell, R. Rahbari, K. Small, I. Martincorena 2025-10-08 Nature 3 90
visibility_off Hotspots of human mutation point to clonal expansions in spermatogonia. Vladimir Seplyarskiy, Mikhail A Moldovan, Evan Koch, Prathitha Kar, Matthew D. C. Neville, R. Rahbari, S. Sunyaev 2025-10-08 Nature 0 86
visibility_off Multiomic assessments of LNCaP and derived cell strains reveal determinants of prostate cancer pathobiology. Arnab Bose, Armand Bankhead Iii, Ilsa Coleman, Thomas Persse, Wanting Han, Patricia C. Galipeau, B. Hanratty, Tony L. Chu, Jared M. Lucas, Dapei Li, Rabeya Bilkis, P. Itagi, Sajida Hassan, Mallory Beightol, Minjeong Ko, R. Dumpit, Michael C. Haffner, C. Pritchard, G. Ha, Peter S Nelson 2025-09-16 The Journal of clinical investigation 0 22
visibility_off Longitudinal single-cell analysis reveals treatment-resistant stem and mast cells with potential treatments for pediatric AML. Denis Ohlstrom, Mojtaba Bakhtia, Hope L. Mumme, Marina E. Michaud, Alejandro De Janon Gutierrez, D. DeRyckere, Katherine E. Ferguson, Franklin Chien, William C. Pilcher, Sarthak Satpathy, Sean C Jordan, Douglas K Graham, Swati S. Bhasin, Manoj K. Bhasin 2025-09-10 Leukemia 0 32
visibility_off Dual targeting of CDK6 and LSD1 is synergistic and overcomes differentiation blockade in AML Lise M Brault, E. Voisset, Mathieu Desaunay, Antonia Boudet, Paraskevi Kousteridou, S. Letard, Nadine Carbuccia, A. Goubard, Rémy Castellano, Yves Collette, J. Vernerey, Isabelle Vigon, J. Pasquet, Patrice Dubreuil, Sophie Lopez, P. de Sepulveda 2025-08-29 EMBO Molecular Medicine 0 35
visibility_off Sex differences in transcription-associated mutagenesis in the human germline Minyoung J. Wyman, Ipsita Agarwal, Marc de Manuel, Natanael Spisak, Molly Przeworski 2025-09-20 bioRxiv 0 7
visibility_off Interplay of replication stress response and immune microenvironment in high-grade serous ovarian cancer Laura Venegas, Stephanie Lheureux 2025-09-05 Frontiers in Cell and Developmental Biology 0 5
visibility_off Decoding the association between mucosal-associated invariant T cells and prostate cancer via multi-omics analysis Lichuan Lai, Rensheng Huang, Keke Si, Junming Huang, Lianli Yin 2025-10-03 Medicine 0 6
visibility_off miR-429 Acts as a Tumor Suppressor in Multiple Myeloma by Regulating Cell Proliferation M. Abdelkarim, I. Limam, Emna Berred, Rachid Kharrat, Brigitte Sola, F. Ben Aissa-Fennira 2025-08-26 Hemato 0 11
visibility_off Nuclear respiratory factor 1 promotes cell survival in multiple myeloma under proteasome inhibition therapy. T. Bruno, Maria Chiara Cappelletto, C. Cortile, S. Di Giovenale, Bruno Amadio, F. de Nicola, I. Falcone, Stefano Giuliani, Belinda Palermo, V. Catena, L. Ciuffreda, F. Cerruti, P. Cascio, Roberta Merola, Serena Masi, Valentina De Pascale, O. Annibali, Silvia Ferraro, S. Gumenyuk, Francesco Pisani, Francesco Marchesi, A. Mengarelli, Maurizio Fanciulli, G. Corleone 2025-09-08 Blood 0 27
visibility_off Chromatin Regulatory Targets for Anticancer Therapeutics. Paige A. Barta, Trever R. Carter, Michael A. Erb 2025-10-06 Chemical reviews 0 14
visibility_off A cytotoxic gene therapy targeting SOX9-positive therapy-resistant medulloblastoma Tong Lin, S. Hutter, Elin Vikström, G. Rosén, Tobias Bergström, Karl O Holmberg, Miao Zhao, G. Giraud, F. Swartling 2025-09-08 Neuro-Oncology Pediatrics 0 26
visibility_off Comprehensive single-cell analysis reveals mast cells' roles in cancer immunity. Hao Qian, Wenbo Wang, Jiaomeng Pan, Ming Zhao, Li Gao, Jia Zeng, Hang Gong, Guangyan Zhangyuan, Zi Li, Mao Zhang, Xia Shen, Yuanchi Weng, Xiaxing Deng, Yingying Huang 2025-10-10 Oncogene 0 13
visibility_off Abstract B024: Uncovering replication stress vulnerabilities in pediatric low grade gliomas using a genome wide CRISPR-Cas9 knockout screen Joohee Lee, Jenna Robinson, Elizabeth M. Gonzalez, Kevin N Zhou, David E. Root, P. Bandopadhayay 2025-09-25 Cancer Research 0 41
visibility_off Designated primers targeted canine TP53 gene hotspot regions Fatimah Ali, A. Al-Zebeeby 2025-08-31 Open Veterinary Journal 0 4
Abstract Title Authors Publication Date Journal/Conference Citation count Highest h-index