Drug-Resistance forecasting

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Manually curated articles on Drug-Resistance forecasting

Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations
visibility_off Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations in mismatch repair genes in methotrexate-resistant HT-29 cells Ahreum Kim, Jong-Yeon Shin, Jeong-Sun Seo 2020-02-27 Experimental and Molecular Medicine, Experimental & Molecular Medicine 5 50 open_in_new
visibility_off Cellular adaptation to cancer therapy along a resistance continuum Gustavo S. França, Maayan Baron, B. King, Jozef P Bossowski, Alicia Bjornberg, Maayan Pour, A. Rao, Ayushi S. Patel, Selim Misirlioglu, Dalia Barkley, K. H. Tang, Igor Dolgalev, D. A. Liberman, Gal Avital, Felicia Kuperwaser, Marta Chiodin, Douglas A. Levine, T. Papagiannakopoulos, A. Marusyk, T. Lionnet, Itai Yanai 2024-07-10 Nature 105 46 open_in_new
Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations

10) at nanomolar concentrations across both sensitive and resistant CRC models Compared with other EGFR inhibitors (osimertinib, erlotinib, afatinib), NT-1 achieved greater inhibitory effects at lower doses. These findings were extended to combinations with emerging pan-KRAS inhibitors, where NT-1 consistently outperformed approved EGFR inhibitors and cetuximab, producing deeper suppression of p-EGFR and p-ERK, and stronger induction of apoptosis. Ex vivo validation using KRAS G12D PDOs confirmed the translational potential of these combinations, demonstrating that NT-1 induces stronger effects than current EGFR inhibitors and can mitigate both intrinsic and acquired resistance to G12Di. Ongoing in vivo studies are assessing NT-1 in combination with G12D selective and pan-KRAS inhibitors to delineate mutation-specific versus pathway-level vulnerabilities. Our combinatorial screening platform provides novel biological insights into KRAS G12D resistance mechanisms in CRC and effectively identifies drug combinations with immediate clinical utility, particularly among approved or clinical-grade drugs. The combination of NT-1 with G12D selective or pan-KRAS inhibitors represents a promising therapeutic strategy to overcome KRAS G12D resistance. Natalie Thielen, Chaoyuan Kuang, Seiya Kitamura, Emiko Nagai, Ning Wei. A high-throughput combination screen identifies NT-1 as a superior compound to overcome KRASG12D inhibitor resistance [abstract]. In: Proceedings of the AACR Special Conference in Cancer Research: RAS Oncogenesis and Therapeutics; 2026 Mar 5-8; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Res 2026;86(5_Suppl_1):Abstract nr B031. "> A, T>G, etc.). The advent of high-throughput DNA sequencing has facilitated the comprehensive, genome-wide assessment of mutation types in human tumors. This has spurred the development of methodology to tease apart the relative contribution of each mutational process by decomposing the set of all mutations into individual signatures. Many mutational signatures have known etiologies. Therefore, mutational signature inference can shed light on the causes of cancer and inform patient treatment. To date, most studies in this area have been performed on solid tumors; consequently, the application of existing methods to hematological cancers has yielded limited results. In this review, we provide an overview of the history and methodology behind mutational signature inference. Here, we present the challenges inherent in its application to hematological cancers and survey the work performed thus far. We highlight how recent research analyzing mutational signatures in normal blood cells can elucidate the beginning of a continuum of mutational processes, from normal hematopoiesis through mature hematological malignancy. Accurate characterization of mutational signatures in cancer development may aid in clinical diagnosis, prognosis, and treatment decisions.">
Abstract Title Authors Publication Date Journal/Conference Citation count Highest h-index
visibility_off Transcriptomic Analysis Reveals an NRF2-Mediated Redox and Metabolic Reprogramming in Sorafenib-Resistant Hepatocellular Carcinoma Cells. Angelo Michilli, C. Bassi, Farzaneh Moshiri, Bruno De Siena, Rosaria Marinaro, E. Callegari, Massimo Negrini, S. Sabbioni 2026-02-11 Biotech (Basel (Switzerland)) 0 42
visibility_off Recurrent Escape from Osimertinib-Induced Senescence Promotes Genomic Instability Associated with Therapeutic Resistance H. McDaid, N. Jamil, Qualia Hooker, Nadjet Cornejal, Dean Hosgood 2026-02-08 bioRxiv 0 20
visibility_off Molecular architecture of the tumor microenvironment caused by BRCA1 and BRCA2 somatic mutations in lung adenocarcinoma Gaoming Liao, Xinbin Yang, Qi Liu, S. Nan, Yan Liu, Jinwei Li, Si Huang, Wang Ning, Xionghai Qin, Gang Xu 2026-02-02 bioRxiv 0 10
visibility_off Upregulation of Genetic Markers of Poor Prognosis following Chemotherapy in Acute Myeloid Leukemia Cells A. Taylor, Michael K. Strasser, Marlee K. Ng, Irit Rubin, A. Kaipainen, A. O. Pisco, Sui Huang 2026-02-15 bioRxiv 0 47
visibility_off Single-cell profiling reveals reprogrammed hierarchy and disrupted immune-stromal ecosystem in TP53-mutated AML Guo Qiu, Zhao-feng Yin, Xiaoyue Lu, Rongtao Xue, Shengjiao Tang, Cuiyan Zhou, Xueping Huang, Menglin Fan, Yanjia Ai, Guangmei Xiang, Luting Wang, Sijian Yu, Guopan Yu, Pengcheng Shi, K. Zhao, Hui Liu, Yu Zhang, Meng Shan, L. Xuan, Jing Xiong, Xi Xu, Qifa Liu, Yu Wang 2026-02-03 Experimental Hematology & Oncology 2 26
visibility_off Identifying cancer cell-state transitions from multimodal single-cell data G. Baselli, Alisa Alekseenko, J. Liaño-Pons, Lefteris Sinanis, Eltjona Rrapaj, Marie Arsenian-Henriksson, Vicent Pelechano 2026-03-04 bioRxiv 0 20
visibility_off Chromosomal instability and chromosome 17p loss drive convergent NDE1 synthetic lethality in metastatic cancer cells Caroline M. Teddy, Jacob P. Hoj, Julia D Caci, Min Lu, Shane T. Killarney, Tal Ben-Yishay, U. Ben-David, Kris C. Wood 2026-02-12 bioRxiv 0 17
visibility_off Clonal morphology-guided combination therapies overcome heterogeneity-driven drug tolerance Xiaoxi Li, Ling Liu, Yuanyuan Yan, Mengfang Yang, Lingli Luo, Yong Jiang, Weijun Ren 2026-02-03 bioRxiv 0 4
visibility_off Integrative dual ctDNA 5mC/5hmC methylomics and clonal reconstruction infer tumor transcription and resistance phenotypes in metastatic prostate cancer A. Sowalsky, Chennan Li, A. Baj, Clara C Y Seo, N. Terrigino, J. Bright, S. Hennigan, I. King, S. Wilkinson, Tzu-Ting Huang, S. Trostel, W. Figg, William L Dahut, David Y. Takeda, Jung-min Lee, F. Karzai 2026-02-05 Research Square 0 25
visibility_off Multiplexed enrichment and tracking of lineages with CloneSweeper Robert J. Vander Velde, Raymond W. S. Ng, Christopher Coté, Sydney M. Shaffer 2026-01-30 bioRxiv 0 6
visibility_off Functional genomics identifies therapeutic options, biomarkers, and resistance mechanisms for high-grade gliomas W. Lin, F. Kosari, James Smadbeck, Michael Barrett, Ryan W. Feathers, J. Hall, Dorsay Sadeghian, Sotiris Sotiriou, Sarah H. Johnson, F. Harris, Taylor Berry, A. Mccune, Stephen J. Murphy, Lindsey Kinsella, Lauren E. Haydu, Diogo Moniz-Garcia, Shannon P. Fortin Ensign, Lin Yang, Angela R. Emanuel, Leila A Jones, J. Schaefer-Klein, Cristiane M. Ida, Marcela A. Salomao, Wendy J. Sherman, Alyx B Porter, Steven S. Rosenfeld, S. Kizilbash, K. Jaeckle, Maciej M Mrugala, Aaron S. Mansfield, M. Borad, B. Bendok, Terry C Burns, Alfredo Quiñones-Hinojosa, John C. Cheville, G. Vasmatzis, P. Anastasiadis 2026-02-03 bioRxiv 0 66
visibility_off A mutation-resolved therapeutic atlas of NRAS-mutant melanoma reveals genotype-selective response to RAS(ON) inhibition and adaptive STAT3 survival Sai Fung Yeung, J. Chen, Cherie Tsz-Yiu Law, Alex Chun Ho Law, Carol Lee, Allen Ming Fai Leung, Mary Chau Po Ki, Ben Ko Chi-Bun, Wu Yue, M. Tong, Kaixi Liang, William C. Cho, M. Siu, K. Chan, C. Leung, S. K. Tsui 2026-03-13 bioRxiv 0 26
visibility_off Targeting Distinct Cell Cycle Nodes Overcomes KRAS/RAS Inhibitor Resistance V. Kumarasamy, Jianxin Wang, Edwin H Yau, Ethan V. Abel, A. Witkiewicz, Erik S. Knudsen 2026-03-12 bioRxiv 0 13
visibility_off Construction and initial validation of key gene network for progesterone resistance in endometrial cancer based on genome-wide CRISPR screening Xinyue Li, Shourong Wang, Ziyi Qiu, Rui Sun, Tong Wang, X. Ren, Binglin Lv, Xiaohong Ma, Lei Cheng, Yao Liu, Jie Jiang 2026-03-03 Scientific Reports 0 25
visibility_off A single-cell atlas linking intratumoral states to therapeutic vulnerabilities across cancers María González-Bermejo, Laura Serrano-Ron, Santiago García‐Martín, Óscar Lapuente-Santana, Ignacio Sanz Portillo, Pablo González-Martínez, G. Gómez-López, Fátima Al-Shahrour 2026-02-19 bioRxiv 0 9
visibility_off EZH2 Inhibition Restores Tumor Suppressor SFRP1 Activity by Reprogramming Extrachromosomal Circular DNA Dynamics in Ovarian Cancer. Tao Han, Qingya Yan, Yaqi Zhang, Yu Gan, Kaifan Li, Liping Guan, Changqin Jing, Ciqing Yang, Pengfei Li, Bo Gao, Xiang Zhou, Qian Hao 2026-02-15 Biology 0 19
visibility_off Perturbation-guided mapping of colorectal cancer cell states to causal mechanisms Soroor Hediyeh-zadeh, T. S. Toh, O. Dufva, Giuseppe Serra, Rashika Jakhmola, C. Fourneaux, Goncalo Rei Pinto, Zijian Fang, G. Picco, Amanda J. Oliver, R. Elmentaite, Till Richter, Ken To, J. P. Pett, Sarah A. Teichmann, Elham Azizi, Florian Buettner, F. Theis, Mathew J. Garnett 2026-03-24 bioRxiv 0 23
visibility_off Paclitaxel-induced germline DNA-damage signatures independent of mismatch repair in C. elegans Yebin Hong, Zifei Liu, Hyun-Min Kim 2026-02-18 Frontiers in Pharmacology 0 3
visibility_off The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing Sofia Jonsson, Andrei Guliaev, Brandon A Berryhill, D. I. Andersson, Hervé Nicoloff 2026-02-27 Nature Communications 0 19
visibility_off Leukemia stem cell expansion cultures reveal clonal drivers of leukemogenesis and therapy response Indranil Singh, Andrea Polazzi, Alex Maya Pombo, Marta López-Osias, C. Bauer, Maria Guarini, P. Sánchez, Luna Goulet, Carmen Gallardo, Daniel Fernández-Pérez, Robert L. Bowman, Alejo E. Rodriguez-Fraticelli 2026-02-25 bioRxiv 0 21
visibility_off Division state reveals hidden genetic regulation during T cell activation and identifies immune disease–linked gene programmes Megan Gozzard, K. Sonehara, Kevin Ly, Tarran S Rupall, Ziying Ke, Ximena Ibarra-Soria, Mohammad Lotfollahi, Blagoje Soskic, Carla P. Jones, O. Bakker, G. Trynka 2026-02-23 bioRxiv 0 52
visibility_off Tabular foundation model predicts alternative lengthening of telomeres (ALT) and identifies SMARCAL1 as a target in ALT-driven cancers D. Bennett, M. Wierdl, S. Chakraborty, Jd Johnson, V. Akingbehin, D. Estevez-Prado, Y. Feng, JJ Morsby, J. Harper, MA Mohammad Nezhady, M. Pan, N. Ocasio-Martinez, JL Catlett, TB Nations, NV Dharia, A. Robichaud, A. Herman, S. Zhang, J. Kelly, J. Steele, M. Rusch, K. Wienand, CD Campbell, G. Alexe, F. Vazquez, G. Getz, Cw Roberts, C. Mullighan, E. Sweet-Cordero, C. Reynolds, B. Koneru, A. Shelat, A. Durbin, E. Bernstein, X. Ma, K. Stegmaier, P. Geeleher, LM Guenther 2026-03-05 bioRxiv 0 51
visibility_off Cellular mechanisms of acquired drug resistance against regorafenib in colon cancer cells Deepu Sharma, Fayyaz Rasool, B. Kumar, R. Verma, Ashutosh Singh, Sri Krishna Jayadev Magani 2026-02-05 bioRxiv 0 4
visibility_off Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-associated DNA damage Alexandra Nusawardhana, Anastasia Hale, Joshua Straka, Claudia M. Nicolae, George‐Lucian Moldovan 2026-02-24 Nucleic Acids Research 0 32
visibility_off Epigenetic state inheritance drivers drug-tolerant persister-induced resistance in solid tumors: A stochastic agent-based model Xiyin Liang, J. Lei 2026-01-30 ArXiv 0 12
visibility_off Metabolic reprogramming controlled by NF-YA alternative splicing creates therapeutic opportunities in colorectal cancer Silvia Belluti, Valentina Mularoni, Natalia Iseppato, Virginia Campani, Mirko Ronzio, Valeria Righi, Laura Cuoghi, Arianna Rinaldi, Tommaso Martinelli, Oneda Cani, Valentina Salsi, Andrea Alessandrini, G. Miserocchi, D. Dolfini, V. Zappavigna, C. Imbriano 2026-03-05 bioRxiv 0 36
visibility_off BRAF inhibitor resistance in melanoma: from resistance mechanisms to therapeutic innovations Yan Shang, Tingping Cao, Junyan Li, Juan Li, Lingnan Zhang, Qiqi Ma, Lanyan Feng, Hailong Zhao 2026-03-11 Molecular Biomedicine 0 5
visibility_off High-throughput mapping of spontaneous mitotic crossover and genome instability events with sci-L3-Strand-seq Peter Chovanec, Trevor Ridgley, Yi Yin 2026-02-05 Nucleic Acids Research 1 4
visibility_off Unravelling genome-wide mosaic microsatellite mutations at single-cell resolution Chunyi Wang, Wenxuan Fan, Weixiang Wang, Yonghe Xia, Jinhong Lu, Xiaoyu Ma, Jichuan Yu, Yunchao Zheng, Yan Luo, Wenlong Li, Qing Yang, Meizhen Lin, Huan Liu, Yangning Lan, Chengyu Li, Xiaodong Liu, Danyang He, Shang Cai, Xiuyan Yu, Dan Zhou, M. Kellis, Xushen Xiong, Qi Xie, Yanmei Dou 2026-02-06 bioRxiv 0 45
visibility_off Aurora kinase A is a synthetic lethal target in FANCA-deficient cancers Dilara Akhoundova, Martín González-Fernández, Aavash Baral, Andrej Benjak, Carmen Perry, Dinda Shezaria Hardy Lubis, Ladina Hörtensteiner, Saskia Hussung, Lea Lingg, S. Maletti, Aino Paasinen-Sohns, Marika Lehner, B. Dislich, E. Vassella, Simone de Brot, Therese Waldburger, Petros Tsiridis, C. Cardozo, Ralph Fritsch, C. Pistoni, Seynabou Diop, Phillip Thienger, Taina S. Kaiponen, Muriel Jaquet, Mariana Ricca, S. Sivakumar, Christopher McDermott-Roe, David E. Root, P. Francica, Sven Rottenberg, M. Rubin 2026-02-06 bioRxiv 0 21
visibility_off miRNA-driven cancer cell plasticity, tolerance and therapy resistance: lessons from melanoma Arianna Ortolano, Rachele Frigerio, G. Ciliberto, L. Fattore, R. Mancini 2026-02-10 Molecular Cancer 1 22
visibility_off Deciphering Treatment Resistance in NSCLC with Single-Cell Sequencing Technology Na Li 2026-02-04 Exploring Science Academic Conference Series 0 5
visibility_off Abstract PS3-06-12: Pre-existing TOP2A-High Cells Drive Resistance to Trastuzumab Deruxtecan in HER2+ Breast Cancer S. Han, M. Jung, J. Lee, S. Rhie 2026-02-17 Clinical Cancer Research 0 4
visibility_off Interpreting cancer genetics through a two-step “evolutionary cascade hypothesis”: bridging neutral and selective perspectives A. Ottaiano, M. Santorsola, Francesco Sabbatino, Roberto Sirica, Francesco Caraglia, Anna Ceccarelli, V. Granata, Ines Simeone, S. Zappavigna, M. Berretta, Giovanni Savarese, Michele Caraglia 2026-02-13 Journal of Translational Medicine 0 49
visibility_off Principles of subclonal gene dosage across human cancer Solrun Kolbeinsdottir, V. Zachariadis, Muyi Yang, Luuk A. Broeils, Christian Sommerauer, Huaitao Cheng, Xinsong Chen, Yingbo Lin, Matias M. Falco, J. Hynninen, S. Hautaniemi, Yizhe Sun, O. Lohi, M. Heinäniemi, S. E. Brage, D. Sarhan, N. Herold, J. Hartman, H. Helgadottir, Felix Haglund de Flon, Anna Vähärautio, Martin Enge 2026-03-18 bioRxiv 0 47
visibility_off Systematic drug profiling across BAF complex perturbations reveals distinct dependencies Katharina Spang, Caroline Barry, Christina Ntasiou, Eleni Aretaki, Maria K. Wolf, Eric Schumbera, Fridolin Kielisch, Lena Bonn, Mareen Welzel, Frank Rühle, Christiane Schäfer, Katja Luck, Sandra Schick 2026-03-13 bioRxiv 0 14
visibility_off LRSomatic: a highly scalable and robust pipeline for somatic variant calling in long-read sequencing data Robert A. Forsyth, L. Harbers, Amber Verhasselt, Ana-Lucía Rocha Iraizós, Sidi Yang, Joris Vande Velde, Christopher Davies, N. Pillay, L. Lambrechts, J. Demeulemeester 2026-02-28 bioRxiv 0 38
visibility_off PSMD14 drives melanoma cell survival and MAPK inhibitor resistance through histone H2A deubiquitination Michael Ohanna, Pierric Biber, Mira Kahil, S. Diazzi, Lauren Lefevre, Frédéric Larbret, Robin Didier, S. Audebert, V. Delmas, Lionel Larue, Sophie Tartare-Deckert, Marcel Deckert 2026-03-02 bioRxiv 0 34
visibility_off CHD4 epigenetically coordinates genomic instability and immunosuppression to drive pan-cancer progression and confer HDAC inhibitor sensitivity Guangxu Fu, Yong Tao, Keyi Feng, Yuxing Chen, Wen Zhang, Zhen Zhang, Guoda Hu, Yunsheng Ou 2026-02-13 Clinical and Experimental Medicine 0 7
visibility_off Targeting glycerophospholipid biosynthesis overcomes chemoresistance driven by SLFN11 loss in Ewing sarcoma Kasturee Chakraborty, Ritambhar Burman, S. Satheesh, Matthew Kieffer, Chandni Karuhatty, Zuo-Fei Yuan, Haiyan Tan, Ankhbayar Lkhagva, Anthony A. High, Xusheng Wang, Alaa Refaat, Nathaniel R. Twarog, Weixing Zhang, Yaxu Wang, Yiping Fan, Qian Li, M. Madan Babu, A. Shelat, Elizabeth Stewart, Michael A. Dyer, P. Bagga 2026-01-31 Cell Death & Disease 0 41
visibility_off Decoding the archipelago: single-cell biomarkers rechart the molecular geography of acute myeloid leukemia Fengjie Kang, Hailong Yuan, Hamed Soleimani Samarkhazan, F. Tavakoli 2026-02-17 Cell Communication and Signaling : CCS 0 6
visibility_off Single-cell RNA editing defines clinically relevant cellular states in chronic myelomonocytic leukemia N. Wickramasinghe, Doan Bui, Surendra Neupane, M. Ferrall-Fairbanks, Michael M Deininger, Eric Padron, Tongjun Gu 2026-03-18 bioRxiv 0 2
visibility_off TET2-mutant clonal hematopoiesis prevents T-cell exhaustion and suppresses cancer metastasis Ai Nhan Thi Le, M. Fujisawa, Giacomo Campo, Yen Thi Minh Nguyen, Tran Bich Nguyen, S. Suma, Y. Suehara, F. Miura, Hiromitsu Araki, K. Makishima, Tatsuhiro Sakamoto, M. Nakayama, Masanobu Oshima, Miwako Kakiuchi, S. Ishikawa, C. Tanikawa, Koichi Matsuda, R. Saiki, Seishi Ogawa, Robert J. MVanner, M. Sakata-Yanagimoto 2026-03-11 bioRxiv 0 37
visibility_off DNA-damaging combination treatments impose genotype-specific constraints on hypermutator evolvability Adam J. Mulkern, Stefan O. Bassler, William Matlock, Athanasios Typas, R. C. MacLean 2026-02-20 bioRxiv 0 3
visibility_off Exploiting synthetic lethality in epithelial ovarian cancer: multi-dimensional approaches beyond DNA damage repair Mandana Bigdeli, Élizabeth Tremblay, Diane Provencher, A. Mes-Masson, Francis Rodier 2026-02-10 Molecular Cancer 0 61
visibility_off Characterization and clinical implications of CpG island methylator phenotypes of resistant tumors Fei Hou, Xu Zhou, Yu-E Huang, Haizhou Liu, Mengqin Yuan, Jiahao Chen, Quan Wang, Wei Jiang 2026-01-30 Clinical Epigenetics 0 22
visibility_off Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs. Sauyeun Shin, Mehdi Liauzun, Jacobo Solorzano, Morgane Le Bras, Christine Jean, Benjamin Fourneaux, M. Doré, Lea Fevrier, I. Belhabib, A. Brunel, C. Neuzillet, Marion Larroque, C. Joffre, Stéphane Rocchi, N. Fraunhoffer, A. Perraud, Muriel Mathonnet, Vera Pancaldi, Laetitia K. Linares, J. Iovanna, Nelson Dusetti, Ola Larsson, R. Nicolle, S. Pyronnet, Corinne Bousquet, Yvan Martineau 2026-02-17 Advanced Science 0 37
visibility_off Patient-Derived in Vitro Models Reveal Insights into Medullary Thyroid Cancer Microenvironment and Resistance to Tyrosine Kinase Inhibitors E. Grassi, V. Ghiandai, G. Gaudenzi, E. Massardi, V. Cirello, Erika Carbone, Davide Gentilini, Sarah Uraghi, G. Gazzano, G. Dionigi, C. Colombo, Giovanni Vitale, L. Fugazzola, L. Persani 2026-02-06 Thyroid 0 23
visibility_off Single-Cell Insights into Cisplatin Resistance Mechanisms in Bladder Cancer Tumor Microenvironment. Linfei Xu, Yongfeng Lin, Guanyu Shi, Limin Zhang, Xingzhang Lin, Tao Zhang 2026-02-01 The Journal of biological chemistry 0 7
visibility_off Single-cell-based identification of drug synergy with immunotherapy via tumor microenvironment remodeling Ziruoyu Wang, Junchi Hu, Kailu Liu, Jie Xu, Jiao Li, Yihang Liu, Qinfeng Ma, Yuehan Dong, Yunmei Zhu, Kai Zhang, Dexin Wang, Xiaobo Wang, Shuai Wang, Jianbo Pan, Shuai Jiang, Jiaxue Wu, Wei Jiang, Ling Zhang, Yongjun Dang 2026-03-01 Journal for Immunotherapy of Cancer 0 7
visibility_off Discrete Transcriptional States Define Biphasic Immune Response and Dynamic CMS Transitions in Colorectal Cancer Khalid Ishani, Dechen Wangmo, Atef Ali, Travis Gates, Zejie Yan, Ava P. Gustafson, Ella Boytim, K. Storey, P. Goffredo, Justin Hwang, Subbaya Subramanian 2026-02-06 bioRxiv 0 54
visibility_off Spatially Integrated Multi-Omics reveals the Multicellular Landscape of Progenitor-Driven Glioblastoma Progression Korbinian Traeuble, Jakob Träuble, Gabriele S. Kaminski Schierle, Matthias Heinig 2026-02-28 bioRxiv 0 2
visibility_off POLQ-driven repair scars shape the immunogenic landscape of homologous recombination-deficient pancreatic cancer Wungki Park, Shigeaki Umeda, Marc Hilmi, Catherine A. O’Connor, Roshan Sharma, Nuray Tezcan, Haochen Zhang, Yingjie Zhu, C. Schwartz, Amin Yaqubie, A.M. Varghese, Kevin Soares, V. Florou, Dae-Kyeum Kim, S. Maron, Guillem A. Martinez, F. Balogun, Caitlin A McIntyre, Daehee Kim, K. Yu, Joanne F. Chou, Akimasa Hayashi, F. Keane, Danny Khalil, W. Chatila, M. Capanu, R. Chaligné, Michael J Pishvaian, C. Bandlamudi, Nicolas Lecomte, Michael F. Berger, O. Basturk, V. Balachandran, D. Pe’er, B. Rousseau, Benjamin D. Greenbaum, Agnel Sfeir, Christine A. Iacobuzio-Donahue, N. Riaz, E. O’Reilly 2026-03-17 bioRxiv 0 63
visibility_off Single-cell analysis of UNC13D-mediated immune and dedifferentiation heterogeneity in acute myeloid leukemia and development of a prognostic model Ziqian Wang, Daobin Zhou 2026-02-01 Translational Cancer Research 0 6
visibility_off Abstract PD3-04: Chromatin remodelling is involved in resistance to CDK4/6 inhibitors in ER+ breast cancer F. Pepe, F. Messina, F. Napolitano, G. Nassa, A. Salvati, D. Memoli, C. Fierro, D. Esposito, S. Belli, C. Ascione, G. Attanasio, A. Vallefuoco, A. Benish, L. Formisano, R. Bianco, A. Servetto 2026-02-17 Clinical Cancer Research 0 16
visibility_off A post-translational regulatory map of chronic antigen-driven human T cell dysfunction Hiroyuki Kojima, C. R. Wayne, Luis F. Somarribas Patterson, Henry Sanford, Tzu-Jou Chen, Ya-Hui Lin, Joshua D. Schoenfeld, Lisa H. F. McGary, Yan-Ting Chen, Korbinian N. Kropp, Beatrice Zhang, Jahan Rahman, Tiffany L. Zhang, Nathalie Ropek, Cameron G. Roberts, Yuxi Ai, Kartikeya M. Menon, A. Hakimi, Jiankun Lyu, Christopher A. Klebanoff, Omar Abdel-Wahab, S. Vardhana, Ekaterina V. Vinogradova 2026-03-06 bioRxiv 0 29
visibility_off Lineage plasticity: a new dilemma in lung cancer treatment Cainan Huo, Yongxuan Wang, Rujia Li, Xiaofei Xie, W. Lyu, Dingke Chen, Yanqin Sun 2026-02-04 Molecular Biology Reports 0 5
visibility_off Tumor metabolic plasticity in therapy resistance: from the Warburg effect to mitochondrial hijacking Y. Tzeng, Emmanuel Naveen Raj, Shi Cheng, Su-Boon Yong, Shih-Chieh Lin, Ren-Wang Peng, Chia-Jung Li 2026-02-26 Theranostics 0 11
visibility_off Fully T2T pedigree assemblies reveal genetic stability and epigenetic plasticity of human centromeres across inheritance and cell-fate transitions Shihua Dong, Xiaoyun Xing, Monika Cechova, Hailey Loucks, Selvamani Vijayalingam, Amber Neilson, M. Sentmanat, Juan Macias, Tianjie Liu, Z. Dong, Benpeng Miao, Wenjin Zhang, Chad Tomlinson, Heather Schmidt, Edward A. Belter, Ming Hu, Xiaoxia Cui, N. Stitziel, K. Miga, Ting Wang 2026-02-17 bioRxiv 0 45
visibility_off A comprehensive review of mechanisms underlying resistance to immune checkpoint inhibitors Alexandre Bertucci, K. Taleb, Emilien Billon, T. Fernez, P. Rochigneux 2026-03-03 Frontiers in Immunology 0 12
visibility_off Evolution of oncogene amplification across 86,000 cancer cell genomes J. Lee, Sohrab Salehi, Matthew A. Myers, Marc J. Williams, Melissa A. Yao, Duaa H. Al-Rawi, J. Lee, Eric G. Sun, Kerstin Thol, Seongmin Choi, Eliyahu Havasov, Asher Preska Steinberg, Michelle Wu, Nicole Rusk, Caitlin Timmons, C. Phua, Stephen Martis, Neeman Mohibullah, P. Manoj, E. Redin, Á. Quintanal-Villalonga, P. Razavi, Sam Aparicio, N. Rekhtman, Viviane Tabar, Mark M. Awad, H. Yu, K. Yu, Andrea Ventura, Andrew Mcpherson, C. Rudin, Sohrab P. Shah 2026-02-13 bioRxiv 0 85
visibility_off scAmp analyzes focal gene amplifications at single-cell resolution Matthew G. Jones, Natasha E. Weiser, King L. Hung, Xiaowei Yan, Sangya Agarwal, J. Luebeck, Aditi Gnanasekar, B. Howitt, Ellis J Curtis, Kevin Yu, John C. Rose, Katerina Kraft, Valeh Valiollah Pour Amiri, Leena Satpathy, V. Bafna, P. Mischel, Howard Y. Chang 2026-02-15 bioRxiv 0 76
visibility_off Predicting mutation-rate variation across the genome using epigenetic data Machiko Katori, Tetsuya J. Kobayashi, Magnus Nordborg, Shoi Shi 2026-02-03 bioRxiv 0 6
visibility_off Genomic and Evolutionary Determinants of Two-hit Frequencies in Tumor Suppressor Genes Nivedita Mukherjee, R. Sabarinathan 2026-02-18 bioRxiv 0 1
visibility_off LINE-1 Transcript Heterogeneity in Non-Small Cell Lung Cancers Is Driven by Host Genomic Context and Conserved Functional Hotspots Yingshan Wang, Kenneth S. Ramos 2026-01-30 Cancers 0 3
visibility_off Ovarian Cancer Susceptibility and Chemosensitivity to KRAS Modulation A. Psaras, Steven J McKay, Janelle Vasquez Vilela, Eddison Ospina Sanchez, Marina G. Cintrón, Kayla K. Elder, Tracy A. Brooks 2026-02-01 International Journal of Molecular Sciences 0 5
visibility_off A genome-wide CRISPR-Cas9 screen identifies TGN46 as a host determinant for H-1PV susceptibility in pancreatic adenocarcinoma G. Labrousse, Nina Suarez, Adèle Nevot, Naïma Hanoun, N. Dusetti, Louis Buscail, C. Murgia, Pierre Cordelier 2026-03-11 bioRxiv 0 18
visibility_off Molecular background of Philadelphia chromosome dependent enhancement of cellular growth and tyrosine kinase inhibitor sensitivity Md. Faruq Hossain, L. Hagenau, Lars R. Jensen, J. Rhode, Thomas Sura, M. G. Salazar, A. Tzvetkova, Corinna Jensen, S. Edwards, H. Dunkel, Stefan Simm, J. Radke, A. W. Kuss 2026-02-19 Experimental Hematology & Oncology 0 13
visibility_off Abstract PR013: Dynamic kinome reprogramming and metabolic rewiring drive adaptive resistance to RAS inhibition in pancreatic cancer Clint A. Stalnecker, Wen-Hsuan Chang, Brandon L. Mouery, Ryan D. Mouery, Oluwadara Coker, A. C. Edwards, Run-Wei Yang, Crystal L Pace, Laura E. Herring, Whitney Stutts, Joshua H. Choe, Alec J. Vaughan, T. Baslan, Ben Z. Stanger, K. Wong, T. Papagiannakopoulos, A. Aguirre, J. Mancias, Adrienne D. Cox, C. Der 2026-03-05 Cancer Research 0 124
visibility_off Conditionally Reprogrammed Cells Preserve Cellular Diversity and Permit Genetic Manipulation: Implications for Cancer Heterogeneity and Tissue Regeneration Shuang Fang, Guangzhao Li, Dilber Nurmurmet, Xiaokui Mo, Chen Fei, S. Choudhury, Nancy Palechor-Ceron, Richard Schlegel, Xuefeng Liu, J. Li 2026-02-04 Serican Journal of Medicine 0 19
visibility_off Reconstruction of epithelial transcriptional trajectories reveals heterogeneous progression and early therapy-resistance programs in high-grade serous carcinoma precursors Michail Sideris, E. Maniati, Tanjina Kader, S. Santagata, Ronny Drapkin, Frances R. Balkwill, R. Manchanda 2026-02-09 bioRxiv 0 22
visibility_off Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans T. Gao, Chen Weng, Isaac Johnson, Michael Poeschla, Jonas Gudera, Emily King, Christopher Rouya, A. Donovan, Lauren Bourke, Ying Shao, E. Márquez, Rahul Tyagi, Leonard I. Zon, J. Weissman, Vijay G. Sankaran 2026-02-18 bioRxiv 0 22
visibility_off Inference of Cancer Drug Cross Resistance Using Only Single-Drug Exposure Data F. J. Whiting, I. Mavrommati, A. Acar, A. I. Garces, U. Banerji, A. Sottoriva, R. Natrajan, Trevor A. Graham 2026-03-13 bioRxiv 0 53
visibility_off Loss of DNA mismatch repair genes leads to acquisition of antibiotic resistance independent of secondary mutations. David E Bautista, J. F. Carr, Cassidy R. Whitehead, Brian Kostoch, Angela M. Mitchell 2026-02-20 PLoS genetics 0 4
visibility_off Reprogramming resistance in advanced lung cancer: epigenetic modulation to restore therapeutic vulnerability. Fang He, Mostafa Hossam El din Moawad, M. Alsaied, Hamza A Abdul-Hafez, H. Alhadrami, A. Azhari, Bashar Abdulhakem Abu Nawas 2026-03-22 Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 0 23
visibility_off Integration of RNA Editing into Multiomics Machine Learning Models for Predicting Drug Responses in Breast Cancer Patients Yanara A. Bernal, Alejandro Blanco, Karen Y. Oróstica, Iris Delgado, R. Armisén 2026-03-01 Biomedicines 0 5
visibility_off Epigenetic and transcriptional control of classical and basal-like cell states in pancreatic ductal adenocarcinoma Christina Parassiadis, Steven A. Johnsen 2026-01-20 Gastroenterology Report 0 4
visibility_off Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration Márk Kerestély, István Narozsny, Levente Szarka, D. Veres, Peter Csermely, D. Keresztes 2026-01-31 Advanced Science 1 12
visibility_off Unraveling small non-coding RNAs with a significant post-transcriptional impact on breast cancer cell signaling, using a combinational sequencing approach K. Katsaraki, V. Stafyla, D. C. Sideris, Andreas Scorilas, C. Kontos 2026-03-23 Functional & Integrative Genomics 0 32
visibility_off Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types S. Sauty, Jacqueline Shine, Hamed Bostan, Jian-liang Li, P. Mieczkowski, Richard F. Loeser, B. Diekman, Dmitry A. Gordenin 2026-02-15 bioRxiv 0 26
visibility_off P023 | SETD2 loss in chronic myeloid leukemia promotes metabolic reprogramming and genomic instability leading to therapeutic resistance and disease progression M. Mancini 2026-03-03 Haematologica 0 22
visibility_off Multi-omics characterization of breast cancer metabolism identifies new metabolic targets Hanneke Leegwater, Xiaobing Zhang, Luojiao Huang, Christine Hoegen, Xuesong Wang, Agnieszka B. Wegrzyn, Thomas Hankemeier, Bob van de Water, E. Danen, A. J. Zweemer, Amy C. Harms, S. L. Le Dévédec 2026-03-09 bioRxiv 0 23
visibility_off Synthetic lethality and DNA damage response targeting in cancer stem cells: a comprehensive review Usamah Sayed, Waleed K. Abdulsahib, Ihsan Khudhair Jasim, H. Malathi, Priya Priyadarshini Nayak, D. Alex Anand, Gunjan Mukherjee, Aashna Sinha, Sadridin Eshkaraev 2026-02-13 Discover Oncology 0 6
visibility_off Dysregulated immune microenvironment in metastatic colorectal cancer S. An, Zhaojin Yu, Jianping Li, Minjie Wei 2026-02-24 Medical Oncology 0 4
visibility_off Single-molecule spatial genomics reveals the multi-scale organization and plasticity of extrachromosomal DNA in glioblastoma Brett Taylor, Weixiu Dong, Tula Keal, Zhaoning Wang, Bharath Saravanan, Zane A. Gibbs, Yohei Miyake, Daisuke Kawauchi, Raghavendra Vadla, Abhinaba Banerjee, Omar M. Elkassih, Sahana Kashyap, Brandon M. Jones, Kseniya Malukhina, Mahsa Nafisi, Timothy Loe, Joseph Bendik, Tom McCallister, Yang Xie, Lei Chang, Clark Chen, Bing Ren, Frank Furnari, Bogdan Bintu 2026-03-07 bioRxiv 0 7
visibility_off A multiplex, prime editing framework for identifying drug resistance variants at scale. Florence M C Abadie, Chase C. Suiter, Nahum T Smith, R. Daza, Mary C. Rominger, P. Parrish, Troy A. McDiarmid, Jean‐Benoît Lalanne, Beth K. Martin, Diego Calderon, Amira Ellison, Alice H. Berger, Jay Shendure, Lea M. Starita 2026-02-01 Cell genomics 0 37
visibility_off Single-Cell Transcriptomic Profile Associated with Sub-Subtype A6 and CRF63-02A6 HIV-1 Strain Infection K. Elfimov, A. Khozyainova, L. Gotfrid, D. Baboshko, D. Kapustin, Polina Achigecheva, V. Ekushov, M. Halikov, Mariya Gashnikova, Tatyana Bauer, T. Tregubchak, Andrey I Murzin, Arina Kiryakina, A. Totmenin, Aleksandr Agaphonov, N. Gashnikova 2026-02-01 Viruses 0 8
visibility_off Insights from Genomic Sequencing of Preclinical Breast Cancer Models Establish Human Parallels to Increase Therapeutic Applicability Anthony J. Schulte, E. Andrechek 2026-02-06 Journal of Mammary Gland Biology and Neoplasia 0 31
visibility_off Functional Characterization of POLE1 Variant Fibroblasts Reveals Replication Stress and Increased Sensitivity to Genotoxic Stress Enas Khdeda, Nora Naumann-Bartsch, Nawres Khdeda, Giulia Cramer, Laura S. Hildebrand, Paula Schiller, Paul Wagner, Franziska Fahrmeier, U. Hüffmeier, Stefanie Corradini, L. Distel, Lukas Kuhlmann 2026-03-01 Diseases 0 36
visibility_off Dynamic optimization of extrachromosomal DNA copy number drives tumour evolution Aditi Gnanasekar, Shu Zhang, Ellis J Curtis, Jun Tang, Vishnu Shankar, I. Wong, Xiaowei Yan, Rui Li, Lu Yang, Melissa A. Yao, Andrea Ventura, Benjamin Werner, Howard Y. Chang, P. Mischel 2026-03-23 bioRxiv 0 17
visibility_off Substantial genomic and methylation variability between MCF-7 sublines H. Atanda, Adam D Ewing 2026-02-19 bioRxiv 0 4
visibility_off An epigenetic bifunctional that toggles between transactivation and repression Ananthan Sadagopan, Maximilian T Carson, Eriks J Zamurs, Shanivi Srikonda, Cary N. Weiss, Michael J Bond, Anurag Sodhi, Katherine A. Donovan, Julia K. Ryan, Eric S. Fischer, K. Stegmaier, Srinivas R. Viswanathan, Benjamin L. Ebert, William J. Gibson 2026-03-20 bioRxiv 0 12
visibility_off Systematic and precise interventions for KRAS-mutant cancers Jinghui Liang, Junxi Wu, Yuan Zhang, Hongyu Wang, Yiyang Zheng, Qing He 2026-03-13 Experimental Hematology & Oncology 0 16
visibility_off Single-nucleus multi-omics delineates distinct epigenetic programs associated with tumor progression in lung adenocarcinoma. Yeji Kim, Huiram Kang, Y. Hwang, Kyung Soo Kim, S. Moon, Jeonghan Kim, Seung Joon Kim, Hae-Ock Lee 2026-02-11 Clinical epigenetics 0 8
visibility_off Therapy-induced rapid drug resistance driven by genome chaos and polyploid giant cancer cells. S. Horne, J. Ye, Guo Liu, Batoul Y. Abdallah, J. Stevens, Henry H Heng 2026-02-01 Cancer letters 0 26
visibility_off Deubiquitination-driven adaptive programs in hepatocellular carcinoma: The emerging role of USP22 in hypoxia, metabolic rewiring, and drug resistance. Haohao Mei, Ni Yan 2026-03-01 Gene 0 1
visibility_off Functional correction and genome integrity with duplex base editing of β-thalassemic hematopoietic stem cells Nikoletta Y Papaioannou, Petros Patsali, Julia Klermund, P. Papasavva, G. Andrieux, L. Koniali, Basma Naiisseh, S. Christou, Maria Sitarou, M. Kleanthous, Toni Cathomen, C. Lederer 2026-02-02 Genome Biology 0 28
visibility_off Application and mechanistic research of novel therapeutic strategies in cisplatin-resistant small cell lung cancer Zhe Chen, Min Qiang, Junxue Dong, Kejian Gong, Xinjun Zhang, P. Huo, Jingjun Zhu, Yifeng Shao, Jianzun Ma, Bowei Zhang, Wei Liu, Mingbo Tang 2026-03-23 Annals of Medicine 0 8
visibility_off Challenges and advances in drug resistance and tolerance in cancer T. Bivona, Itai Yanai, Fabio Calabrò, F. Mechta‐Grigoriou, G. Corleone, Marta Di Martile, A. Tocci, Piera Tocci, S. Vaccarella, Marilia Ferriero, A. Alimonti, E. Ruppin, P. Nisticò, A. Bagnato, G. Blandino 2026-03-04 Journal of Experimental & Clinical Cancer Research 0 64
visibility_off Single Cell RNA Transcriptomics of Mantle Cell Lymphoma Reveals the Presence of Treatment-Resistant Subclones at the Time of Diagnosis. Dmitry Manakov, M. Klanova, M. Kolář, R. Ivanek, Florian Geier, Julien Roux, Tomas Zikmund, L. Winkowska, E. Kriegova, J. Manakova, L. Tušková, Silvia Spanikova, Alexandra Scasna, M. Trněný, Pavel Klener 2026-03-09 American journal of hematology 0 33
visibility_off Multiscale RNA editing analysis reveals cell type–specific regulatory programs across disease states in acute myeloid leukemia Tongjun Gu, Doan Bui, G. S. Guru Murthy, A. Kwitek 2026-02-06 bioRxiv 0 40
visibility_off MYC-Mediated Functional Manifestation of IDH1 Mutations in Intrahepatic Cholangiocarcinoma Confers Sensitivity to (+)-JQ1 Fangyanni Wang, Xinyu Liu, Ning Zhang, R. Kong 2026-01-30 International Journal of Biological Sciences 0 3
visibility_off Emerging trends and converging evidence in tumor evolution: A comprehensive review. Chenqi Jin, Weiqi Li, Boqiang Liu, Lu-Qi Cao, S. Stefan, Luoxi Yuan, Xin Yu, Liang Shi, Hong Yu 2026-02-01 Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 1 17
visibility_off Changes in EGFR activity following CRISPR/Cas9-editing of the EGF binding domain Jelena Popovic, Anna Hahut, G. Torres, Andrew Vincent, Nashaly Soto-Echevarria, Brian Wray, E. Bartom, T. Paunesku, C. Goodman, G. Woloschak 2026-01-31 Scientific Reports 0 46
visibility_off Application of Targeted Sequence Capture (TSC) for Genetic Characterization of Antibody Producing Cell Lines S. O'Brien, Jake T Leinas, Jodi Grantham, Neha Patel, Howard Clarke 2026-02-01 Biotechnology Journal 0 7
visibility_off Systematic identification of tissue-conserved m 6 A sites reveals a stable epitranscriptomic regulatory layer controlling essential genes Sumin Jo, Tinghe Zhang, Shou-Jiang Gao, Yufei Huang 2026-03-20 bioRxiv 0 4
visibility_off It’s a kind of MAGIC: uncovering the origins of chromosomal instability D. Gómez-Peregrina, César Serrano 2026-02-05 Signal Transduction and Targeted Therapy 0 5
visibility_off Glycolytic-inflammatory crosstalk mediated by Glyco-PMF-Rux hub genes drives PMF progression and ruxolitinib resistance. Shujing Zhang, Muhammad Sameer Ashaq, Yi Wang, Yuan Li, Baobing Zhao 2026-02-27 Genes & genomics 0 8
visibility_off Small Interfering RNA Strategies to Overcome Drug Resistance in Cancer: Pathway Targeting and Translational Advances. S. Bardaweel, Rima Hajjo, D. Sabbah, Daliah Al Qasem 2026-02-18 The Eurasian journal of medicine 0 30
visibility_off Substantial Deceleration of Adaptation of HIV-1 Within 1,500 Generations in an Experimental Evolution: A Genomic Perspective Ali Movasati, Christine Leemann, Kathrin Neumann, Rongfeng Chen, Lygeri Sakellaridi, K. Metzner, R. Regoes 2026-02-12 bioRxiv 0 37
visibility_off Therapy-resistant subclones as drivers of progression in aggressive variant prostate cancer. Quang Tran, Shuai Guo, Zhihui Zhang, Noshad Hosseini, P. van Loo, A. Aparicio, Wenyi Wang 2026-03-01 Journal of Clinical Oncology 0 71
visibility_off Follicular Helper T Cells and B Cell Maturation in Patients with 22q11.2 Deletion Syndrome and Recurrent Infections N. Alsaati, K. Beigel, K. Maurer, S. Henrickson, Montana S. Knight, Audrey Green, V. Giunta, D. McGinn, Bekah Wang, T. B. Crowley, Donna M. McDonald-McGinn, Kathleen E. Sullivan 2026-02-03 Journal of Clinical Immunology 0 18
visibility_off Effect of loss of KDM6A-mediated genomic instability and metabolic reprogramming on response to therapeutic perturbations in bladder cancer. S. Goswami, Pratishtha Singh, Ranit D. Rozario, Bidisha Chakraborty, Swadhin Meher, D. Raychaudhuri, Aminah J. Tannir, Yang Li, Anurag Majumdar, Jessalyn Hawkins, Yun Xiong, Philip L. Lorenzi, Padmanee Sharma, K. Akdemir, P. Pilié, Byron H. Lee 2026-03-01 Journal of Clinical Oncology 0 21
visibility_off Therapeutic synergies that overcome carboplatin resistance in triple-negative breast cancer. Julia E Altman, Aaron D Valentine, Nina Dashti-Gibson, Emily K. Zboril, David C. Boyd, Rachel K. Myrick, Amy L. Olex, Mikhail G. Dozmorov, J. Harrell 2026-02-03 Journal of experimental & clinical cancer research : CR 0 9
visibility_off Senescence-associated and immune-related 9p21.3 locus genes in colorectal cancer: epigenetic architecture, molecular landscape and therapeutic possibilities D. A. Lisitsa, V. V. Shindyapin, Artem R. Nurislamov, O. N. Demidov, D. А. Bogdanova 2026-02-11 Frontiers in Cell and Developmental Biology 0 3
visibility_off Pan-cancer inference and validation of hypermorphic, hypomorphic and neomorphic mutations Somnath Tagore, Samuel Tsang, Carla Tangermann, Lucas Zhongming Hu, Sven Diederichs, G. Mills, Andrea Califano 2026-02-01 Nature Genetics 0 15
visibility_off Integrative multiomics analysis and CRISPR screening identify functional noncanonical translation loci in the mouse immune system Eric Malekos, V. Smaliy, Susan Carpenter 2026-02-24 bioRxiv 0 4
visibility_off MTFP1 drives pancreatic cancer liver metastatic colonisation by regulating mitochondrial metabolism reprogramming Yang Chen, Gaowei Jin, Lihuang He, Yu-Na Dong, Yan-nan Zhang, Han-Xiang Guo, Yi-ting Xu, Ziyang Wei, Bin-Fei Dang, Chunyang Mu, Wanyue Cao, Yizhen Zhang, Xiao-Bao Wei, Yu Feng, Yun-Hua Liu, Qi Zhang, Ting-Bo Liang 2026-02-09 Gut 0 6
visibility_off The impact of epigenetics on tumor metabolism: Friend or foe in drug response? Serena Castelli, M. Franchini, Luigi Ferraro, Nicolò Mangraviti 2026-02-09 Frontiers in Epigenetics and Epigenomics 0 8
visibility_off Cell confinement initiates a delayed but heritable loss of chromosomes Steven H. Phan, Mai Wang, Kayla R. Snare, Jonah Kandell, Jeneille S. Deans, P. Rompolas, Guilherme P F Nader, D.E. Discher 2026-02-03 bioRxiv 0 26
visibility_off Reovirus resistance in tumors mediated by elevated ISG expression: overcoming therapeutic resistance via JAK/STAT pathway modulation. Yuxin Yang, Xiaojin Lin, Liang Chen, Yuting Fan, Xiaowei Dou, Jing Zhang, Yingchun Zhang, Dan Liang, Xing Zhao 2026-03-06 Virology journal 0 3
visibility_off Breaking Resistance in BRAF-Mutant Melanoma: Novel Strategies and Biomarkers for Optimizing Targeted Therapies. Manar A. Al Hindawi, Nourhan E Omran, M. H. Mostafa, Aya M. Alshihabi, M. El‐Gamal, Hany A. Omar 2026-02-01 European journal of pharmacology 0 27
visibility_off Abstract B015: Leveraging patient-derived organoids and matched 2D models to elucidate resistance mechanisms to KRAS inhibition in pancreas cancer Nicolas Lecomte, Elias-Ramzey Karnoub, E. Kang, Florencia Velez-Cortes, L. Kim, Jerry P Melchor, Christine A. Iacobuzio-Donahue 2026-03-05 Cancer Research 0 13
visibility_off Chromosome 3p Deletion Leads to Extensive Genomic Alterations in Diverse Cancers and Confers Synthetic Lethality in Uveal Melanoma. Mitchell C. Cutler, P. B. Howland, M. Hejna, Jun S. Song 2026-02-19 Cancers 0 12
visibility_off Resistance to Targeted Therapy in AML: Current Challenges and Emerging Treatment Strategies C. Stafylidis, P. Diamantopoulos 2026-03-01 Journal of Clinical Medicine 0 3
visibility_off Decoding Leukemic Stem Cells in AML: From Identification to Targeted Eradication. E. Apostolidou, Vasileios Georgoulis, Dimitrios Leonardos, Leonidas Benetatos, Eleni Kapsali, E. Hatzimichael 2026-01-30 Diseases 0 36
visibility_off Dissecting multi-gene virulence phenotypes with base editing requires consideration of target-independent mutagenesis Joshua P. M. Newson, Sandra Gawlitt, Sneha Sundar, R. Regoes, Chase L. Beisel, W. Hardt 2026-02-12 bioRxiv 0 82
visibility_off Comprehensive Cytogenetic and Genomic Profiling of the Murine AML12 (Alpha Mouse Liver 12) Hepatocyte Cell Line. Darine Y. Asar, Stefanie Kankel, Diandra T. Keller, K. Hardt, Sarah K. Schröder-Lange, Eva M. Buhl, Thomas Liehr, Ralf Weiskirchen 2026-02-24 Cells 0 8
visibility_off Extrachromosomal circular DNA: a potential clinical therapeutic target in malignant tumors Hao Zhang, Enqing Zhuo, Meng Li, Junxiao Feng, Xingjuan Shi, Xiaoou Sun 2026-02-14 Cellular & Molecular Biology Letters 0 3
visibility_off EGFR and IRE1α pathways are associated with distinct immunomodulatory gene expression profiles in NSCLC cells with acquired resistance to EGFR TKIs. Yi-Shiuan Wang, H. Chou, En-Chi Liao, Hsin-Yi Chen, Meng-Wei Lin, yu-shan Wei, Li‐Hsun Lin, Yi-Ru Chang, Han Meng, Yueh-Feng Wen, H. Chan 2026-02-01 Archives of biochemistry and biophysics 0 34
visibility_off Centrosome architecture and m6A-dependent gating of p53 surveillance after whole-genome doubling D. Migliorati, Alessia Mattivi, Gian Mario Moretta, Selene Tessadri, Nicole Cona, Giorgia Pellizzaro, M. Pancher, Mattia Furlan, L. Coscujuela, Martin Wegner, Marine. H. Laporte, M. Libergoli, Feryel Soualmia, Stefano Biressi, T. Tebaldi, A. Quattrone, A. Inga, E. Jacotot, V. Hamel, Paul Guichard, Mattia Pelizzola, M. Kaulich, M. Burigotto, Luca L. Fava 2026-02-25 bioRxiv 0 35
visibility_off Acquired resistance of cancer therapies: Mechanisms and perspectives. Manli Wang, Xiao-Gang Zhai, Jiayao Li, Jiale Chen, Xiyue Gai, Xun Liu, Yu Liu, Qinghua Zhou, Chong Chen 2026-03-13 Chinese medical journal 0 9
visibility_off Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors Lamberto De Boni, S. Claridge, Shalini Nath, Kassianne Tofani, Benjamin D. Stein, Eric Park, S. Steiner, O. Elemento, C. Pauli, Benjamin D. Hopkins 2026-02-01 iScience 0 7
visibility_off Comparative Analysis of the Transcriptomic Response to Cisplatin in Drug-Sensitive and Drug-Resistant Testicular Germ Cell Tumors. M. Khan, Doha Shokry, Raya I. Boyd, Ratnakar Singh, Michael J. Spinella 2026-02-10 Cancers 0 12
visibility_off Novel driver gene MDC1 confers homologous recombination repair deficiency and genomic instability in chemoresistant relapsing ovarian cancer. Michael A. Diaz, Nicole Gull, Pei-Chen Peng, Kruttika Dabke, J. Baker, Jennifer Sun, J. Alvarado, Benjamin Bastin, Nimisha Mazumdar, C. Santiskulvong, Andrew J. Li, Beth Y. Karlan, B. Rimel, Sarah Parker, S. Gayther, Michelle R. Jones 2026-03-06 Journal of translational medicine 0 85
visibility_off Decoding Sarcoma Drug Resistance: From Molecular Mechanisms to Precision Interventions Guizhen Lyu, Dongbing Li 2026-03-17 Anti-Cancer Agents in Medicinal Chemistry 0 9
visibility_off Mutational signatures in cancer genomes alter protein sequence motifs in cellular signaling networks Jigyansa Mishra, M. Bayati, Zoe P. Klein, K. Cheng, Omar M. Wagih, Nina Adler, Maria Farina-Morillas, A. Bahcheli, J. Reimand 2026-02-05 bioRxiv 0 48
visibility_off Abstract PS3-06-19: Phylogenetic and Transcriptomic Analyses Reveal Specific Adaptations for Progression of Breast Cancer M. Russo, P. Raj-Kumar, J. Liu, A. Praveen-Kumar, A. Kovatich, A. Tan, H. Hu, C. Shriver, X. Lin 2026-02-17 Clinical Cancer Research 0 6
visibility_off Studies on the functionality of the TC-NER ERCC6-M1097V protein variant frequently found in Louisiana patients with PCa upon UV damage Oluwatobi Ogundepo, Arrigo De Benedetti 2026-02-03 Frontiers in Oncology 0 3
visibility_off T‐cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor‐Exhausted T cells to terminally exhausted T cells Tong Zhu, Xiaoyu Teng, Qinlian Jiao, Yidan Ren, Yunshan Wang, Maoxiao Feng 2026-02-01 Clinical and Translational Medicine 0 14
visibility_off Single-cell Landscape of T Cell Heterogeneity in Kawasaki Disease: STAT3/JAK Axis Regulates the Lineage Differentiation Bias of Th17 Cells Sirui Song, Yanfang Zong, Yanbing Xu, Liqin Chen, Yuanyuan Zhou, Leihao Chen, Guang Li, Tingting Xiao, Min Huang 2026-03-20 bioRxiv 0 8
visibility_off Unraveling novel transposable elements (TEs)-driven gene dysregulation in non-small cell lung cancer (NSCLC) by integrated transcriptomic and TEs analysis Sahadevan Shrinidhi, R. Jansi, A. Khusro 2026-02-01 Computational biology and chemistry 0 31
visibility_off Mismatch repair deficiency reshapes glioblastoma through immune suppression rather than hypermutation Andrew J. Li, Thomas K. Sears, C. Horbinski 2026-03-16 The Journal of Clinical Investigation 0 11
visibility_off From Signaling Pathways to Combination Therapy: Bioactive Compounds against Cancer Stem Cells P. Charan, Nikitha Pai, Nivruthi A Naik, Nandana Thuyyath, A. Joseph, Sahiti Danthuluri, Shravani Shriya Palanki, N. Patel, Kousalya Lavudi 2026-02-02 Stem Cell Reviews and Reports 0 9
visibility_off CO07 | Single-cell sequencing reveals pathways and perturbations predictive of central nervous system dissemination in B-cell acute lymphoblastic leukemia L. Cappelli 2026-03-03 Haematologica 0 14
visibility_off The Mechanisms of Tumor Susceptibility Associated with BRCA1/BRCA2 Genetic Mutations Zhenan Shi 2026-02-02 Theoretical and Natural Science 0 1
visibility_off CRISPR-based functional genomics for dissecting therapeutic dependency in primary acute myeloid leukemia samples. Zhendong Cao, Sixiang Yu, Jacqueline Peng, D. Barrett, Yuqiao Liu, Jonathan H Sussman, Changya Chen, Anusha Thadi, Li Liu, Fatemeh Alikarami, Jason Xu, Martin Carroll, Kai Tan, K. Bernt, Junwei Shi 2026-02-01 Molecular cell 0 40
visibility_off Happening in the Prostate Tumor Microenvironment: Ion Channels and Extrachromosomal DNA Driving Phenotypic Plasticity. S. Darbandi, Alfonso Urbanucci, S. Hakkola, Juanita Gujral, M. Darbandi, A. Eraky, S. Nair, Goutam Chakraborty, Ashutosh K. Tewari, Natasha Kyprianou 2026-02-03 The Prostate 0 21
visibility_off Gastrointestinal Stromal Tumors: Molecular Mechanisms of Drug Resistance and Advances in Therapeutic Strategies. Jing Ding, Huachuan Zhang, Zhou Da, D5X X Zhi, Chen Yan, Zhao Fazhi 2026-02-22 Journal of gastroenterology and hepatology 0 7
visibility_off Oncogenes and tumor suppressor genes are enriched in stop-loss mutations generating protein extensions L. M. Boll, Joan Antoni Martorell, Nafiseh Khelghati, Marta E. Camarena, C. Vianello, Juan Carlos García-Soriano, Eva Santamaría, Idoia Artoleta, Silvia Sáez-Valle, J. Perera-Bel, Puri Fortes, M. M. Albà 2026-03-16 bioRxiv 0 8
visibility_off The Histone-Modified Landscape: Core Mechanisms of Osimertinib Resistance in EGFR-Mutant Lung Cancer. Jingyi Yang, Minpu Zhang, Chundi Gao, Xiaoyu Yao, Changgang Sun, Zhuang Jing 2026-02-19 Cancer letters 0 22
visibility_off Integrative multi-omics defines melanoma drug response networks and ARID1A-dependent resistance mechanisms. C. G. Barker, Sumana Sharma, Ana Mafalda Santos, Konstantinos-Stylianos Nikolakopoulos, Athanassios D. Velentzas, Cristina Tormo-Garcia, Anushka Sharma, Franziska Völlmy, A. Minia, V. Pliaka, Joseph Clarke, M. Altelaar, Gavin J. Wright, Leonidas G. Alexopoulos, D. Stravopodis, E. Petsalaki 2026-02-18 Molecular systems biology 0 30
visibility_off Functional cooperation between the B-cell receptor and NOTCH1 in regulating metabolic reprogramming in chronic lymphocytic leukemia. Amelia Fascì, F. Vallone, Nahal Nabelsi, E. Viry, Ilenia Sana, Alessia Morabito, S. Seghezzi, Noemi Anna Pesce, Matteo Rovere, Nadia Bertola, Chloé Duculty, Silvia Ravera, S. Mouhssine, M. Muzio, P. Ghia, C. Vitale, M. Coscia, E. Moussay, G. Gaidano, John N Allan, Richard R Furman, J. Paggetti, T. Vaisitti, Silvia Deaglio 2026-03-23 Leukemia 0 87
visibility_off Innovative Drug and Prodrug Candidates in Cancer Treatment Targeting TP53 Mutations: Challenge and Hope Raed M. Al‐Zoubi, Mai Elaarag, Ayman A. Zarour, Khalil Garada, Sally R. Al-Zoubi, Z. Fares, A. Al-Qudimat, Mohanad Shkoor, Abbas Khan, Mona A Sawali, Hiba Bawadi, Z. Zakaria, M. A. Zoubi, Abdelali Agouni, Khalid Alrumaihi 2026-02-10 Drug Development Research 0 12
visibility_off Mechanisms Underlying Immunotherapy Resistance in Microsatellite-Stable Colorectal Cancer Jinlan Di, Jianlei Liu, Xiaochun Zhang 2025-12-11 Bratislava Medical Journal 0 2
visibility_off Deciphering selection patterns of somatic copy-number events Tom L. Kaufmann, Adam Streck, Florian Markowetz, P. van Loo, RF Schwarz 2026-03-03 bioRxiv 0 71
visibility_off Abstract PS4-10-23: Uncovering Mechanisms Driving Phenotypic Distinctions between Breast Cancer Cells with Different p53 Mutations using a 3D Microfluidic Platform L. Sakala, K. Ravi, Y. Zhang, E. Hurt, J. Park, M. Nikkhah, J. LaBaer 2026-02-17 Clinical Cancer Research 0 4
visibility_off Post-translational protein lactylation modification in lung cancer: an emerging targeted therapeutic strategy Yongxuan Li, Zhaoyu Li, Xingfei Liu, Zhengzhou Qiu, Ruilin Zhang, Huan Li, Chenggen Gao, Changying Guo 2026-03-11 Frontiers in Immunology 0 3
visibility_off Model selection in preclinical nucleic acid therapeutics research Peter L. Oliver, Alyssa C. Hill 2026-02-09 Communications Biology 0 3
visibility_off From Gene Knockouts to Genome Remodeling: Large DNA Fragment Deletion Technologies in Plants Jiayi Hou, Hui Li, Feng Zhang, Dan Yang, Yan Xiong, Xiaoyue Zhu, Mingzhang Wen 2026-03-01 Plants 0 21
visibility_off Multiaxial Biophysical Control of Oncogenic Phase Separation by Indoleamines: A Proof-of-Concept Synthesis of Landscape-Level Regulation D. Loh, L. Chuffa, F. Seiva, R. Reiter 2026-02-06 bioRxiv 0 20
visibility_off Mitochondrial DNA Variation in the D-LOOP and ND Loci identified in the Kenyan Population: Potential Implications for precision Oncology Eva A. Nambati, Belinda Azzam, Eunice Githua, Ngure Kirosh, Lydia S. Eyase, Solomon K. Langat, Sharon Ariga, W. Cheriro, F. Eyase, Wallace Bulimo 2026-03-14 bioRxiv 0 21
visibility_off The GENEVA platform models tumor mosaicism to reveal variations of responses to KRAS inhibitors and identify improved drug combinations. Johnny Yu, Jung Min Suh, K. D. Popova, Kristle Garcia, T. Joshi, Bruce Culbertson, Jessica B Spinelli, Vishvak Subramanyam, Kevin Lou, Trey Charbonneau, K. Shokat, Jonathan S. Weissman, Hani Goodarzi 2026-02-24 Nature cancer 0 14
visibility_off Expansion of preexisting cancer driver mutant clones is induced by the genotoxic carcinogen benzo[b]fluoranthene in MutaMouse lung Jennifer B Faske, Binsheng Gong, D. LeBlanc, J. Funk, G. Zhou, Sabrina Kehm, P. White, Timothy W. Robison, A. Zeller, Carole L. Yauk, F. Marchetti, Barbara L Parsons 2026-03-01 Toxicological Sciences 0 14
visibility_off Insertional activity of human Alu and L1 retrotransposons is associated with DNA repair pathways and genome instability in cancer M. Suntsova, Aleksander Modestov, Elizaveta Rabushko, Nikolai Komarov, I. Gaziev, Anastasia Novosadskaya, Anastasiya Barysionak, G. Zakharova, N. Shaban, Anna Khristichenko, Anna A. Emelianova, Marianna A. Zolotovskaia, E. Poddubskaya, A. Seryakov, Anton Buzdin 2026-02-07 Computers in biology and medicine 1 22
visibility_off Integrative single-cell, spatial, and bulk transcriptomics reveal an FMR1–FTO axis linked to the immune-excluded phenotype in gastric cancer Chenxi Mao, Miao Zhang, Kangjie Zhou, Yidong Hong, Yiqian Han, Luming Zhao, Mingtong Liang, Jingzhou Zhang, Nan Hu, Fenglei Wu 2026-03-09 Frontiers in Immunology 0 16
visibility_off Abstract B057: Targeting Glioblastoma Cell State Plasticity for Enhanced Therapeutic Efficacy S. Cirigliano, R. Singhania, J. Nicholson, Isha Monga, C. Haywood, A. Muley, S. Giacobetti, Howard A. Fine 2026-03-23 Cancer Research 0 10
visibility_off Epigenetic Deregulation of Transposable Elements Links Developmental Processes and Tumorigenesis Chi F Lynch-Sutherland, Peter Stockwell, Aniruddha Chatterjee, Michael R. Eccles, Erin C. Macaulay 2026-03-01 International Journal of Molecular Sciences 0 11
visibility_off Genomic Instability and Adaptive Evolution Induced by RFA Insufficiency in Saccharomyces cerevisiae. Runbiao Zhang, Liyan Tian, Min He, Kejing Li 2026-01-30 Current issues in molecular biology 0 4
visibility_off Abstract PS2-07-30: Structural Variants in Homologous Recombination Repair/DNA Damage Response Pathways as an Alternative Mechanism of Genomic Instability in Breast Cancer A. Da Cruz Paula, D. Muldoon, A. Gazzo, M. Repetto, C. Schwartz, H. Dopeso, D. Ross, H. Wen, H. Zhang, L. Norton, E. Brogi, C. Bandlamudi, B. Weigelt, F. Pareja 2026-02-17 Clinical Cancer Research 0 92
visibility_off Abstract LB-A009: Neutrophils Drive Cancer Initiation in BRCA-Carriers via NF-κB Epigenetic Reprogramming of Luminal Progenitors into Aberrant Basal-Like Cells Hannah F Dewhurst, Camilla Paleari, Arianna Calcinotto, Letizia Boffa 2026-03-18 Cancer Immunology Research 0 8
visibility_off cfGWAS reveal genetic basis of cell-free DNA end motifs Huanhuan Zhu, Yan Zhang, Linxuan Li, Shuang Zeng, Xinyi Zhang, Ying Lin, Rijing Ou, Lin Wang, Xiameizi Li, Yu Wang, J. Zeng, Yu Lin, Chuangze Xu, Guodan Zeng, Lingguo Li, Rong Zhao, Yongjian Jia, F. Luo, Meng Yang, Yuxuan Hu, Han Xiao, Xun Xu, Jian Wang, Aifen Zhou, Haiqiang Zhang, Xin Jin 2026-02-14 Nature Communications 0 20
visibility_off Abstract B018: ZNF384 Orchestrates Cell-State Reprogramming and Kinome Remodeling in KRAS G12C Inhibitor Resistance Chendi Li, Anahita Nimbalkar, Christopher J. Graser, Melissa D. Vieira, M. U. Syed, Qian Qin, Barbara Karakyriakou, Christopher Ott, Luca Pinello, Franziska Michor, Aaron N. Hata 2026-03-05 Cancer Research 0 7
visibility_off Abstract B031: A high-throughput combination screen identifies NT-1 as a superior compound to overcome KRASG12D inhibitor resistance Natalie Thielen, Chaoyuan Kuang, Seiya Kitamura, Emiko Nagai, Ning Wei 2026-03-05 Cancer Research 0 3
visibility_off Abstract B034: Genetic and non-genetic mechanisms of resistance to KRAS inhibition in CRC S. Alonso, Kevan Chu, Marie J Parsons, Elizabeth Granowsky, J. Shia, R. Yaeger, Lukas E. Dow 2026-03-05 Cancer Research 0 97
visibility_off Long noncoding RNAs in tumor stemness: emerging mechanisms and therapeutic opportunities E. M. Reis, D. S. Bassères 2026-02-25 Frontiers in Genetics 0 28
visibility_off A06 | TP53 in myeloid neoplasms M. Voso 2026-03-03 Haematologica 0 56
visibility_off A base editing resource for functional annotation of DNA repair variants in breast-derived cell models Wardah Masud, Ludovica Russo, Vincent Chapdelaine-Trépanier, Samuel B. Hayward, Wei He, M. Ciró, C. Mercurio, Han Xu, Alberto Ciccia, Raquel Cuella-Martin, G. Leuzzi 2026-03-26 Frontiers in Cell and Developmental Biology 0 33
visibility_off A07 | Optical genome mapping: the new frontier of cytogenomic diagnosis? L. Zanatta 2026-03-03 Haematologica 0 12
visibility_off P036 | Germline and somatic cohesin genes alterations in pediatric acute lymphoblastic leukemia Domenico Gaspari 2026-03-03 Haematologica 0 0
visibility_off Applying biotechnology to overcome cancer drug resistance and improve public health outcomes Franklin Adjei, Bernard Frempong, Augustine Afriyie 2026-02-01 Osong Public Health and Research Perspectives 0 2
visibility_off A distal CTCF-binding site drives MYC expression plasticity in a negative feed-forward loop Chenyin Gao, M. Martino, Ayushi Chaurasiya, F. Casagrande, Jia Pei Lim, Yuri S. van Ekelenburg, W. Feng, Yan Liu, Barbara A. Scholz, Pragyan Mishra, Mallikarjuna Thippana, Dennis Torkornoo, Phong KC Chau, Rabia Khan, T. Tannaes, I. Tzelepis, Ilyas Chacoua, Natalie Geyer, S. Meltzer, A. H. Ree, Marco Gerling, Johan Hartman, N. Kiani, Rolf Ohlsson, A. Göndör 2026-01-31 bioRxiv 0 31
visibility_off MORC2 promotes acute myeloid leukemia by silencing LINE-1 retrotransposon Shuai Wang, Fu-Bo Wang, Zixuan Li, Nana Wang, Zhidong Gu, Zhimin Gu 2026-02-21 Functional & Integrative Genomics 0 4
visibility_off Prevalence and spectrum of homologous recombination repair mutations in patients with metastatic prostate cancer from India H. Baskarane, Rishabh Jain, M. Divakar, Amlesh Seth, B. Nayak, S. Bakhshi, R. Sahoo, Akash Kumar, Aparna K. Sharma, S. Kaushal, K. Haresh, Vishakha Hooda, P. Vasudeva, P. Singh, Rishika Agarwal, S. Vasundhara, N. Agarwal, A. Batra 2026-02-23 The Oncologist 0 17
visibility_off Characterization of the clonal hierarchy and immunophenotype of PTPN11 mutations in acute myeloid leukemia. S. Fobare, Chi Sharpe, Kate Quinn, Kinsey Bryant, Linde A. Miles, Robert L. Bowman, C. Cheney, Casie Furby, Marissa Long, Kaytlynn Fyock, Ben Wronowski, James R. Lerma, K. Mrózek, D. Nicolet, T. Sesterhenn, Megan E. Johnstone, Jianmin Pan, Shesh N Rai, C. Pasare, Nives Zimmermann, Wen-Mei Yu, Cheng-Kui Qu, Andrew J. Carroll, R. Stone, Eunice S. Wang, J. Kolitz, Bayard Powell, J. Perentesis, Ann-Kathrin Eisfeld, E. Hertlein, John C. Byrd 2026-02-23 JCI insight 0 80
visibility_off A Robust Framework for Predicting Mutation Effects on Transcription Factor Binding: Insights from Mutational Signatures in 560 Breast Cancer Genomes Hüseyin Hilmi Kilinç, Burçak Otlu 2026-02-17 bioRxiv 0 12
visibility_off Abstract B005: Accelerating epigenetic vulnerability mapping for drug-repurposing and combination design in glioblastoma James G Nicholson, Sara Lucchini, Xinyu Zhang, Agatha Ryabova, Y. Lim, Niamh Baker, T. Millner, S. Brandner, S. Marino 2026-03-23 Cancer Research 0 6
visibility_off Abstract A028: Non-genetic resistance to multi-selective RAS(ON) inhibitors in NRAS-mutant melanoma Sungsoo Kim, Haesong Park, Minah Kim, Hee Won Yang 2026-03-05 Cancer Research 0 10
visibility_off Glioblastoma cell plasticity: A new paradigm in glioblastoma therapeutic resistance. T. Xiao, Zhiling Wei, Minghua Wua 2026-02-13 Biochimica et biophysica acta. Reviews on cancer 0 3
visibility_off The c-Myc-USP14-PFKP axis sustains chemoresistance in pancreatic ductal adenocarcinoma. Pengyu Wang, Weihua Guo, Yang Yang, Yongjie Xie, Fengyi Yin, Jiaqi Li, Xuejing Shi, Pei Cao, Chaozhe Ma, Bowen Ding, Chunhua She, Xiangting Hu, Xinyang Li, Lingling Ma, Shouyi Li, Yumin Wang, Danqi Fu, Jing-Xian Hu 2026-03-01 Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 0 7
visibility_off Drug-Tolerant Persister Cells and Tumor Dormancy in NSCLC: A New Frontier in Overcoming Therapeutic Resistance. Mumtu Lalla, Akshay Ratnani, Jihua Yang, Meng Wang, Haiying Cheng 2026-02-28 Cancers 1 3
visibility_off Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity Jihyeon Yu, Ju-Chan Park, Heesoo Uhm, Yong-Woo Kim, Hyeon Woo Im, Sangsu Bae 2026-02-11 Advanced Science 0 16
visibility_off Prime Editing Driven Functional Genomics: Bridging Genotype to Phenotype in the Post-Genomic Era. S. N. Begum, Syed K. Hasan 2026-02-10 International journal of molecular sciences 0 4
visibility_off Diverse transcriptomic and mutational patterns but limited functional pathway alterations in patient-derived Sézary syndrome cells. Evelyn Andrades, Arnau Iglesias, Mariano R Maqueda, T. Lobo-Jarne, Jessica González, Joan Bertran, David Conde, Eva Rodriguez, Beatriz Bellosillo, Ramon M. Pujol, Anna Bigas, Lluís Espinosa, F. Gallardo 2026-02-01 The Journal of investigative dermatology 0 8
visibility_off Single-cell genomics highlight MYC-associated metabolic activation and altered cell interactions in T-prolymphocytic leukemia progression Linus Wahnschaffe, Dennis Jungherz, T. A. Müller, T. Pemovska, A. Pichler, Stéphanie Poulain, Edith Julia, S. Timonen, Martin Böttcher, Qu Jiang, D. Beverungen, Julia Bischoff, Marek Franitza, T. Georgomanolis, Kerstin Becker, Michael Hallek, D. Mougiakakos, T. Zenz, S. Mustjoki, Emmannuel Bachy, C. Herbaux, A. Schrader, N. Pflug, Philipp B. Staber, T. Braun, Marco Herling 2026-03-09 Nature Communications 0 59
visibility_off Abstract B010: Mutational landscape of RTK–RAS signaling pathway in acute myeloid leukemia: Insights from whole exome sequencing Harsh Goel, P. Tanwar 2026-03-05 Cancer Research 0 17
visibility_off Isolated signals in BCL2, MYC, BCL6, and DDIT3 FISH: implications for genetic alterations and protein dysregulation Z. Wei, Qiuyue Chen, Zhenbo Feng, Fang Tang 2026-02-11 Pathology and Oncology Research 0 1
visibility_off Universal Baseline for in vitro Selection of Genetically Encoded Libraries Kejia Yan, G. M. Lima, Tara Bahadur, V. Albert, Zoe O’Gara, Gary Bao, Christin Kossmann, William Kirby, F. B. Mejia, Matthew L. Michnik, Kristen Maiorana, R. Derda 2026-02-15 bioRxiv 0 36
visibility_off A stem cell aging clock links biological age deviation to clinical outcome in acute myeloid leukemia Hongcheng Chen, Pengwei Dong, Jianing Xu, Guanlin Wang 2026-03-18 bioRxiv 0 4
visibility_off Overcoming Chemoresistance in Glioblastoma: Mechanisms, Therapeutic Strategies, and Functional Precision Medicine. M. Kordyukova, T. K. Bulgakov, M. A. Sorokina, Olga M. Kudryashova, T. Abakumova, Valeriya Meshcheryakova, Ilya V. Grigoriev, I. V. Senko, Evgeny K. Shevchenko, Vsevolod V. Belousov 2026-02-26 International journal of molecular sciences 0 16
visibility_off Investigation of the expression and potential mechanistic role of BYSL in acute myeloid leukemia Jie Gao, Fujue Wang, Yingying Chen, Pengqiang Wu, Yongqian Jia, Xianmin Song 2026-03-19 Clinical and Experimental Medicine 0 9
visibility_off Integrative Insights into Cancer Progression: Molecular Mechanisms, Epigenetic Regulation, and Emerging Therapeutic Targets T. Chaudhary, Saumya Das, Avijit Mazumder, S. Aggarwal 2026-02-24 Current Cancer Therapy Reviews 1 23
visibility_off Understanding and Overcoming Antibody-Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer. Minji Seo, Jangsoon Lee, N. T. Ueno 2026-03-24 Advanced science 0 1
visibility_off Abstract B049: Overcoming treatment adaptation to RAS(ON) inhibition in NRAS/HRAS mutant pediatric tumors Roketa Henry, Ayush Attery, A. Shelat, Anand G. Patel 2026-03-05 Cancer Research 0 41
visibility_off Abstract IA010: Spatiotemporal determinants of KRAS effector signalling in PDAC: From subclonal evolution to stromal–immune niches Dieter Saur 2026-03-05 Cancer Research 0 4
visibility_off BioBloom, a method for barcoded saturation mutagenesis of an entire bacterial genome Max Schubert, Edward Sukarto, Fatima R. Martin, J. E. Mancuso, Amy Spens, Tom Pedersen, Keren Isaev, H. Greene, Nathan D Hicks, Una Nattermann, J. Liu, Devon A. Stork, E. DeBenedictis 2026-02-05 bioRxiv 0 18
visibility_off Multiomic analysis of clonal development reveals new regulators of leukemic cell growth. Gracia Bonilla, Alexander Morris, Sharmistha Kundu, Anthony Ducasse, Grace Kirkpatrick, Jelena Milosevic, N. E. Jeffries, Kashish Chetal, Emma E Yvanovich, Ting Zhao, Jun Xia, Rana Barghout, David T. Scadden, Michael K. Mansour, Robert E. Kingston, David B. Sykes, François E. Mercier, Ruslan I. Sadreyev 2026-02-04 Genes & development 0 12
visibility_off Cancer-associated KBTBD4 mutations induce differentiation defects and confer a unique therapeutic vulnerability Rohit Sivaprasad, Kristijonas Žemaitis, David Linfeldt, Sudip Ghosh, Anne de Snaijer, Mattias Magnusson, F. Ek, Jenny Hansson, Agatheeswaran Subramaniam 2026-03-14 bioRxiv 0 16
visibility_off Multi-omic Study of Cutaneous T-Cell Lymphoma Reveals Single Cell Clonal Evolution in Progression and Therapy Resistance. Hannah K. Dorando, Jared Andrews, Oam Khatavkar, N. Borcherding, Yulia Korshunova, Gabriela Hakeman, Rodrigo Borgiani Panigassi, Phuong Vo, Ruei-yuan Tu, Diep Tran, Chaz C. Quinn, J. Schmidt, Jahnavi Aluri, Michael T Harmon, Marcus P Watkins, Anastasia Frank, M. Cooper, Amy C. Musiek, N. Mehta-Shah, Jacqueline E. Payton 2026-02-09 Blood 0 25
visibility_off Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer. Brian J. Nelson, Lyanne A Delgado-Coka, N.Ye Marchenko, Luisa F. Escobar-Hoyos, Kenneth R Shroyer, Alisa Yurovsky, T. Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers 2026-03-01 Molecular oncology 0 85
visibility_off Detection of mitochondrial DNA mutations in T cells following 5-FU or cisplatin exposure Catherine Kirkpatrick, C. M. Quick, Steven R. Post, Yuet-Kin Leung, R. Dings, C. Paulos, L. Burdine, Yong-Chen William Lu 2026-03-01 Cell Reports Medicine 0 46
visibility_off P064 | XPO1 mutations drive BCR hyperactivation and early disease progression in chronic lymphocytic leukemia C. Cosentino 2026-03-03 Haematologica 0 3
visibility_off CO54 | Biallelic loss of RB1 and LPAR6 at 13q14 drives key cell cycle abnormalities in T-cell acute lymphoblastic leukemia F. Servoli 2026-03-03 Haematologica 0 4
visibility_off In Silico Analysis of Age-Associated Immune Gene Expression Alterations in Human Dermal Fibroblasts Vural Yilmaz 2026-03-16 Current Aging Science 0 0
visibility_off Abstract A014: Mapping the genetic landscape of KRAS mutant cancer cells using combinatorial CRISPR screens Rand Arafeh, Xiang Zhang, Laura Chang, Arshia Z. Hassan, Lydia Sawyer, Helen Wang, Joey H. Li, James McFarland, Joshua M. Dempster, Peter C. DeWeirdt, John G Doench, Chad L. Myers, William Hahn 2026-03-05 Cancer Research 0 73
visibility_off Extrachromosomal circular DNA are functional, heritable units that expand genomic plasticity and confer resilience Dana R. MacGregor, Christopher A. Saski 2026-02-25 Frontiers in Plant Science 0 6
visibility_off Nucleotide-resolution mapping of regulatory elements via allelic readout of tiled base editing. Basheer Becerra, S. Wittibschlager, Z. M. Patel, A. P. Kutschat, Justin Delano, Eric Che, Anzhelika Tauber, Ting Wu, Marlena Starrs, C. S. Horstmann, Sophie Müller, Madelynn N. Whittaker, E. Sylvander, Manfred Lehner, Michael I Love, B. Kleinstiver, Martin Jankowiak, Daniel E. Bauer, D. Seruggia, L. Pinello 2026-03-03 Nature communications 0 34
visibility_off Prime Editing Exhibits Limited Genome-Wide Off-Target Effects in Cellular and Embryonic Gene Editing. Jitan Zheng, Mingdi Wu, Xueyan Wang, Zhenrui Zuo, Chikai Zhou, Erwei Zuo, Yangqing Lu 2026-02-28 Cells 0 23
visibility_off Advances and resistance adaptation in BTK-targeted therapy for B-cell malignancies. Sieun Yang, Jihye Oh, S. Hwang, J. Paik, I. Hwang 2026-02-01 Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 0 11
visibility_off Abstract A035: Functional genomics screen reveals SFPQ as a regulator of cell state in IDH-mutant glioma E. Yilmaz, Aybala Samancioglu, Alexander Jucht, Sedef Sarac-Yalcinkaya, M. Suva, T. Bagci-Onder 2026-03-23 Cancer Research 0 20
visibility_off CO32 | ARQ531 targets MAPK–S6K1 signaling and synergizes with lenalidomide in RAS-mutant and wild-type multiple myeloma D. Soncini 2026-03-03 Haematologica 0 20
visibility_off Two codes of RNA editing by deamination in human diseases Dong Min, Suyeon Lee, Young-suk Lee, Jun Cho 2026-02-01 Experimental & Molecular Medicine 0 3
visibility_off Abstract A034: Functional genomics screen reveals SFPQ as a regulator of cell state in IDH-mutant glioma E. Yilmaz, Aybala Samancioglu, Alexander Jucht, Sedef Sarac-Yalcinkaya, M. Suva, T. Bagci-Onder 2026-03-23 Cancer Research 0 20
visibility_off A new cancer progression model: from synthetic tumors to real data and back Daniela Volpatto, S. G. Contaldo, Simone Pernice, Marco Beccuti, F. Cordero, R. Sirovich 2026-02-09 bioRxiv 0 3
visibility_off Tumor-immune spatiotemporal co-evolution as a paradigm for overcoming therapy resistance in advanced prostate cancer Jun-Chao Xue, Kaisen Liao, Mengzhao Zhang 2026-03-11 Frontiers in Immunology 0 13
visibility_off BCL11B enhancer hijacking by t(14;16)(q32;q24) translocation defines a novel high-risk subtype of T-ALL. Kaito Mimura, Akira Kaino, Y. Ochi, Yunchao Chang, Masafumi Seki, June Takeda, Saori Katayama, H. Niizuma, Y. Sasahara, Yoko Mizoguchi, Maiko Shimomura, Ryosuke Koyamada, Rintaro Ono, Daisuke Hasegawa, Kazuki Mitani, Hirohito Kubota, Satoshi Yoshihara, N. Hiramoto, Akihito Otsuki, Yasunobu Okamura, F. Katsuoka, Kengo Kinoshita, M. Hasegawa, Marina Togo-Ohno, Hirona Maeda, N. Kakiuchi, Mai Takeuchi, A. Sato-Otsubo, S. Kato, Kentaro Watanabe, K. Katayama, Seiya Imoto, Y. Shiraishi, K. Koh, Souichi Suenobu, E. Hiyama, S. Goyama, Atsuo Kikuchi, Seishi Ogawa, Motohiro Kato, Y. Nannya, Junko Takita, Kenichi Yoshida 2026-03-05 Blood 0 71
visibility_off Abstract B042: Therapeutic options for cancers with oncogenic Ras mutations Leonard J Ash, Ottavia Busia-Bourdain, Elesha McGrath, Akriti Khanal, O. Gavaudan, Amani Nation, Dennis Lam, B. Ely, Dustyne J. Steele, Ahava Collado, Jillian M. Silva, Jacqueline Galeas, Weigang Qiu, F. McCormick, A. Wolfe 2026-03-05 Cancer Research 0 10
visibility_off BRCA1-A and LIG4 complexes mediate ecDNA biogenesis and cancer drug resistance. Oliver W. Chung, Shun Yao, Ling Wang, Fu Yang, Lauren Schier, M. Aldana, Christian G. Cerda-Smith, Haley M. Hutchinson, Kris C. Wood, Weijia Su, M. Khasraw, Lee Zou, Dale A. Ramsden, Z. Zhang 2026-03-11 Proceedings of the National Academy of Sciences of the United States of America 0 7
visibility_off Mechanistic Modeling of Intrinsic Drug Resistance in Prostate Cancer Apoptosis Signaling D. Mangrum, Stacey D. Finley 2026-03-11 bioRxiv 0 1
visibility_off ATRX loss couples genome instability at a G-rich repeat to dysregulation of human alpha-globin expression Yuqi Shen, Kinam Gupta, Sue Mei Tan-Wong, Sean Wen, Chris Fisher, Liezel Tamon, Nicholas J Proudfoot, R. Gibbons, D. Higgs 2026-02-14 Nature Communications 0 51
visibility_off Translating Molecular Insights into Effective Targeting of Glioblastoma Stem Cells. Shilpi Singh, Deepak Singh Kapkoti, Gatikrushna Singh 2026-03-07 Cancers 0 6
visibility_off Mitochondrial genome editing tools: prospects in animal breeding. Xu Yan, Mingyue Chen, Shunkai Yang, Yuyang Guo, Yichao Dai, Yutong Chen, Haijiang Zhong, Taisen Ma, Dingrui Zha, Yutao He, Baiyu Li, X. Jia, Long Guo, Jianhong Hu, Yinghui Wei, Xiao-xu Chen 2026-02-01 Journal of genetics and genomics = Yi chuan xue bao 0 18
visibility_off Molecular-Genetic Mechanisms of Somatic Cell Reprogramming for Reproductive Biology Applications V. Malogulko 2026-02-01 International journal of medical sciences 0 0
visibility_off The Role of the Microbiota in Cancer Drug Resistance and Emerging Therapeutic Strategies. Chang Che, Yelu Zhou, Liyu Chen, Sifan Li, Daiming Fan, Yuanyuan Lu, Xiaodi Zhao 2026-02-07 Cancer letters 0 7
visibility_off Stochastic Evolutionary Control in Heterogeneous Populations Peng Chen, J. Pachter, Jacob G. Scott, Michael Hinczewski 2026-03-13 bioRxiv 0 34
visibility_off PARP Inhibition in Prostate Cancer: Current Status, Resistance Mechanisms, and Clinical Challenges Takashi Matsuoka, Shusuke Akamatsu, Christopher J. Ong, M. Gleave, Yuzhuo Wang 2026-03-26 Cells 0 12
visibility_off Impact of non-genetic heterogeneity of BRAF-mutant colon cancer organoids on growth kinetics, drug sensitivity and Wnt dynamics. Viktoria Zieger, Ellen Woehr, Jasmin Traichel, Tilman Brummer, R. Zengerle, Sabrina Kartmann, Stefan Zimmermann 2026-03-15 International journal of cancer 0 10
visibility_off Abstract B035: Investigating adaptive responses in KRAS/LKB1 co-mutant tumors Mikoto Kobayashi, Yi Bao, Fan Yang, Fred Li, Caleb Cheng, Yuanyuan Qiao, A. Chinnaiyan 2026-03-05 Cancer Research 0 171
visibility_off Mendelian randomization followed by single-cell RNA sequencing exploration identifies effector memory CD4+ T cells as a risk factor for myasthenia gravis Zhaolin Ren, Hao He, Zhi Cai, Peijun Li, Zhou Liu, Haihong Zhou 2026-02-13 Medicine 0 5
visibility_off Evolutionary and Microenvironmental Determinants of Therapeutic Resistance: Integrative Frameworks for Dynamic Precision Oncology Rudy Alejandro Herrera Rosales, Jorge Che Enseñat, Maria Mercedes de la Torre Bustamante, José Arnulfo Perez Carrillo, Esteban Marrufo Sumano, Yulieth Viviana Reyes Maldonado, Genaro Escobar Cruz, Wilmer Rene Cujilema Guillin 2026-03-02 IECCMEXICO 0 0
visibility_off Large-scale sequencing study of de novo regulatory Tandem Repeats (TRs) identifies new ASD (Autism Spectrum Disorders) candidate genes integrating gene expression mapping, brain scRNA-seq and organoid models. Maria Cristina Rodriguez Fontenla, P. Carballo-Pacoret, S. Dominguez-Alonso, J. González-Peñas, Mara Parellada, C. Arango, Á. Carracedo 2026-02-13 Research square 0 21
visibility_off Abstract PS2-13-07: Disrupted epithelial differentiation and mitochondrial remodeling as early events in BRCA-associated carcinogenesis Q. Chartreux, M. Haro, J. Brand, A. Li, B. Rimel, S. Gayther, H. Dinh, F. Madeiros, K. Lawrenson 2026-02-17 Clinical Cancer Research 0 8
visibility_off Colorectal cancer as a complex adaptive system: integrating the hallmarks of cancer with complexity theory Luis R. Basbus 2026-02-03 Frontiers in Oncology 0 0
visibility_off Decoding NOTCH1: From T-Cell Development Guardian to Driver of Pediatric T-Cell Lymphoblastic Lymphoma. Fran Leijnen, T. Lammens 2026-02-23 International journal of molecular sciences 0 33
visibility_off SPINK2 silencing suppresses leukemic proliferation and restores myeloid commitment via MECOM downregulation in acute myeloid leukaemia. A. B. Ventura, Tiziana Loconte, Amer Ahmed, Lucia Deligio, A. Negri, G. d'Angelo, D. Di Molfetta, P. Cauchy, B. Mandriani, X. Zhang, C. Pasciolla, A. Rana, A. Iacobazzi, G. Loseto, M. Cives, L. Viggiano, F. Lasorsa, A. Guarini, M. C. Vegliante, S. Ciavarella, Giancarlo Castellano, G. Fiermonte, Giacomo Volpe 2026-03-03 Cell death discovery 0 41
visibility_off Immune evasion in prostate cancer: resolving the cold tumour paradox via a hybrid discrete-continuum computational framework. A. Ntlokwana, E. Mudimu, M. Ntwasa 2026-03-25 None 0 8
visibility_off Exploring the Potential of Receptor Silencing in the Tumor Microenvironment by RNA Interference Karina Mayumi Tani Bezerra de Melo, Beatriz Mendonça Alves Bandeira, Pedro Vinícius Silva Novis, Micaela Evellin dos Santos Silva, Ingrid Andrêssa de Moura, A. C. D. Freitas, A. J. D. Silva 2026-02-01 Biomolecules 0 8
visibility_off Therapy-induced androgen receptor signaling as a candidate upstream driver of B7-H3–linked immune exclusion in melanoma: mechanisms and translational opportunities Adrian P. Mansini, John R. Hyngstrom, Kyle T. Amber 2026-03-25 Frontiers in Medicine 0 9
visibility_off A hierarchical Bayesian framework for inferring mitochondrial clonal selection from single-cell data. Qianqian Song, Xiaobo Zhou, Aoqi Wang, Yanfei Wang, Xiaona Liu, Qing Wang, Sen Guo, Jianguo Wen 2026-02-12 Research square 0 10
visibility_off Mutational signatures in hematological malignancies F. Sartori, João Vitor Paes Pontes, P. Campregher, Thomas LaFramboise 2026-02-02 Einstein 0 16
visibility_off Targeted native long-read sequencing of DNA methylation alterations following CRISPR-Cas9-induced double-strand breaks in human cells. Yingzi Zhang, Mengge Wang, Chongwei Bi, Mo Li 2026-03-10 BMC research notes 0 15
visibility_off Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and BAP1 loss. S. Camp, M. He, Michael S. Cuoco, Amanda E Garza, Sherin Xirenayi, Z. Bakouny, Eddy Saad, J. El Masri, Erica M Pimenta, K. Meli, C. Labaki, Breanna M. Titchen, Yun Jee Kang, J. Horst, Rachel Trowbridge, E. Shannon, K. Helvie, Aaron R Thorner, S. Vigneau, Angie Mayorga, Jahnavi Kodali, Hannah Lachmayr, Meredith Bemus, Pengsheng Chen, Haiteng Deng, Jihye Park, T. Choueiri, Kevin Bi, E. V. Van Allen 2026-02-20 Science advances 0 81
visibility_off Abstract B023: Identification of TME-dependent resistance and emergence of persister cells to KRAS inhibition N. Khairkhah, Ali Namvar, E. Lasse-Opsahl, M. Ibrahim, Carlos E Espinoza, Megan Faunce, L. Rober, M. Pasca di Magliano, Stefanie Galbán 2026-03-05 Cancer Research 0 38
visibility_off Abstract PS2-11-01: Lmtk2: a novel driver of endocrine resistance in ER+ breast cancer A. Detry, S. Marigliano, J. Heinen, A. Bass, C. Jones, R. Muthyala, M. Goetz, J. Hawse 2026-02-17 Clinical Cancer Research 0 9
visibility_off Gene duplication is associated with gene diversification and potential neofunctionalization in lung cancer evolution P. Ashford, A. Frankell, Zofia Piszka, Camilla S. M. Pang, M. Abbasian, Maise Al Bakir, M. Jamal-Hanjani, N. Mcgranahan, C. Swanton, Christine A. Orengo 2026-02-19 Genome Research 0 75
visibility_off Progress in RNA‐Targeted Therapeutics for Human Diseases Wangzheqi Zhang, Aimin Jiang, Bin Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, X. Fang, Linhui Wang 2026-02-01 MedComm 1 21
visibility_off Mechanistic overview and suggested strategies to overcome BCL-2 inhibitor resistance in TP53-mutated acute myeloid leukemia Umar Iqbal, R. Shallis 2026-03-18 Frontiers in Cell and Developmental Biology 0 25
visibility_off Multidimensional tumor heterogeneity and its role in therapeutic resistance Nida Mubin, M. Alnukhali, Nayab Ahmad, J. Driscoll, Anis Ahmad 2026-03-25 Frontiers in Immunology 0 25
visibility_off Activation of endogenous retroviruses in tumor cells and their immunomodulatory mechanisms: from molecular basis to clinical translation Jintong Zhang, Yanhua Zhang, Xiaochun Peng 2026-03-23 Frontiers in Oncology 0 5
visibility_off Metabolic permissiveness: how tissue context shapes cancer. Chrysanthi Moschandrea, C. Frezza 2026-02-09 Genes & development 0 11
visibility_off Unannotated noncoding transcripts as a source of intratumor heterogeneity in malignant cell states. Xiaolan Zhou, Limin Lin, Yu Chen, Guang Yang, Ting Ni, Zhaozhao Zhao 2026-03-16 Science China. Life sciences 0 8
visibility_off Advances in immunotherapy for colorectal cancer: overcoming resistance in mismatch repair-proficient tumors. Mohammad Reza Keivany, Elham Shojae, Mohammadreza Besharatloo, Hanieh Latifi, A. Barjasteh 2026-02-19 Cancer cell international 0 4
visibility_off Abstract B020: TRIM7 Inhibition Blocks RTK/RAS Pathway Driven Tumor Proliferation Independent of Mutation and in the Setting of KRASi Resistance Yuhui Chen, Marc Morra, Haur Kato, Kevin Li, Ulhas Bhatt, Kevin M. Gayler, Grace Elliott-Fromm, N. Oien, Julio Medina, Taylor H Schreiber, G. Fromm 2026-03-05 Cancer Research 0 15
visibility_off Position-dependent variant effects reveal importance of context in genomic regulation Sambina Islam Aninta, Ryan Tewhey, Carl G. de Boer 2026-03-18 bioRxiv 0 4
visibility_off Targeting ACSS2 Disrupts Metabolic-Epigenetic Crosstalk to Restore Apoptosis and Temozolomide Chemosensitivity in Pancreatic Neuroendocrine Tumors. Qin Dang, Liangju Peng, Yinrong Niu, Xuan-Hao Pan, Zeng Ye, Ting Wang, Yan Wang, Jiahao Wu, Zheng Li, Heli Gao, Miaoyan Wei, Qiangsheng Hu, Guixiong Fan, Desheng Jing, Junfeng Xu, S. Ji, Xianjun Yu, Xiaowu Xu, Yi Qin 2026-03-03 Cancer letters 0 37
Abstract Title Authors Publication Date Journal/Conference Citation count Highest h-index