ecDNA forecasting

This page was last updated on 2026-03-30 10:24:48 UTC

Manually curated articles on ecDNA forecasting

Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations
visibility_off Extrachromosomal DNA in Cancer. V. Bafna, P. Mischel 2022-05-24 Annual review of genomics and human genetics 50 107 open_in_new
visibility_off Extrachromosomal DNA: An Emerging Hallmark in Human Cancer. Sihan Wu, V. Bafna, Howard Y. Chang, P. Mischel 2021-11-09 Annual review of pathology 98 140 open_in_new
visibility_off EcDNA hubs drive cooperative intermolecular oncogene expression King L. Hung, K. Yost, Liangqi Xie, Quanming Shi, K. Helmsauer, J. Luebeck, R. Schöpflin, Joshua T. Lange, R. Chamorro González, Natasha E. Weiser, Celine Y. Chen, Maria E. Valieva, I. Wong, Sihan Wu, S. R. Dehkordi, Connor V. Duffy, K. Kraft, Junfang Tang, Julia A. Belk, John C. Rose, M. Corces, Jeffrey M. Granja, Rui Li, Utkrisht Rajkumar, Jordan Friedlein, A. Bagchi, Ansuman T. Satpathy, R. Tjian, S. Mundlos, V. Bafna, A. Henssen, P. Mischel, Zhe J. Liu, Howard Y. Chang 2020-11-20 bioRxiv 131 146 open_in_new
visibility_off Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers Hoon Kim, Nam Nguyen, Kristen M. Turner, Sihan Wu, A. Gujar, J. Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi, S. Amin, E. Yi, F. Menghi, J. Schulte, A. Henssen, Howard Y. Chang, C. Beck, P. Mischel, V. Bafna, R. Verhaak 2020-07-19 Nature genetics 429 140 open_in_new
visibility_off Chromothripsis drives the evolution of gene amplification in cancer Ofer Shoshani, Simon F. Brunner, R. Yaeger, P. Ly, Yael Nechemia-Arbely, D. H. Kim, Rongxin Fang, Guillaume A. Castillon, Miao Yu, J. S. Z. Li, Ying Sun, Mark Ellisman, B. Ren, P. Campbell, D. Cleveland 2020-12-23 Nature 358 154 open_in_new
Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations

Abstract Title Authors Publication Date Journal/Conference Citation count Highest h-index
visibility_off Dynamic optimization of extrachromosomal DNA copy number drives tumour evolution Aditi Gnanasekar, Shu Zhang, Ellis J Curtis, Jun Tang, Vishnu Shankar, I. Wong, Xiaowei Yan, Rui Li, Lu Yang, Melissa A. Yao, Andrea Ventura, Benjamin Werner, Howard Y. Chang, P. Mischel 2026-03-23 bioRxiv 0 17
visibility_off Evolution of oncogene amplification across 86,000 cancer cell genomes J. Lee, Sohrab Salehi, Matthew A. Myers, Marc J. Williams, Melissa A. Yao, Duaa H. Al-Rawi, J. Lee, Eric G. Sun, Kerstin Thol, Seongmin Choi, Eliyahu Havasov, Asher Preska Steinberg, Michelle Wu, Nicole Rusk, Caitlin Timmons, C. Phua, Stephen Martis, Neeman Mohibullah, P. Manoj, E. Redin, Á. Quintanal-Villalonga, P. Razavi, Sam Aparicio, N. Rekhtman, Viviane Tabar, Mark M. Awad, H. Yu, K. Yu, Andrea Ventura, Andrew Mcpherson, C. Rudin, Sohrab P. Shah 2026-02-13 bioRxiv 0 85
visibility_off scAmp analyzes focal gene amplifications at single-cell resolution Matthew G. Jones, Natasha E. Weiser, King L. Hung, Xiaowei Yan, Sangya Agarwal, J. Luebeck, Aditi Gnanasekar, B. Howitt, Ellis J Curtis, Kevin Yu, John C. Rose, Katerina Kraft, Valeh Valiollah Pour Amiri, Leena Satpathy, V. Bafna, P. Mischel, Howard Y. Chang 2026-02-15 bioRxiv 0 76
visibility_off KRAS-extrachromosomal DNA drives intratumoral heterogeneity in gastric cancer. Rong Guan, Chenxi Li, Xinchun Dai, Yanyan Wang, Yiyuan Zhang, Xiao Liang, Shan Yu, Zhizhou Li, Kexian Dong, Mengdi Cai, Jie Wu, Xueyuan Jia, Hao Wang, Dapeng Hao, Songbin Fu, Wenjing Sun 2026-03-05 Oncogene 0 13
visibility_off Extrachromosomal circular DNA: a potential clinical therapeutic target in malignant tumors Hao Zhang, Enqing Zhuo, Meng Li, Junxiao Feng, Xingjuan Shi, Xiaoou Sun 2026-02-14 Cellular & Molecular Biology Letters 0 3
visibility_off Profiling Extrachromosomal Circular DNA (ecDNA) in Cancer via Next-Generation Sequencing: A New Frontier in Tumor Evolution and Therapy Resistance Sareh Bakhshandeh Bavarsad, Narges Mohammadgholiha, Mohammad Javad Hayati, Javad Yaghmoorian Khojini, F. Haghighi, Amirhossein Azimi, Seyed Mohammad Gheibi-hayat 2026-03-17 Anti-Cancer Agents in Medicinal Chemistry 0 15
visibility_off Single-molecule spatial genomics reveals the multi-scale organization and plasticity of extrachromosomal DNA in glioblastoma Brett Taylor, Weixiu Dong, Tula Keal, Zhaoning Wang, Bharath Saravanan, Zane A. Gibbs, Yohei Miyake, Daisuke Kawauchi, Raghavendra Vadla, Abhinaba Banerjee, Omar M. Elkassih, Sahana Kashyap, Brandon M. Jones, Kseniya Malukhina, Mahsa Nafisi, Timothy Loe, Joseph Bendik, Tom McCallister, Yang Xie, Lei Chang, Clark Chen, Bing Ren, Frank Furnari, Bogdan Bintu 2026-03-07 bioRxiv 0 7
visibility_off Fast and accurate resolution of ecDNA sequence using Cycle-Extractor M. Faizrahnemoon, J. Luebeck, King L. Hung, Suhas S. P. Rao, Gino Prasad, I. Wong, Matthew G. Jones, P. Mischel, Howard Y. Chang, Kaiyuan Zhu, V. Bafna 2026-03-13 bioRxiv 0 76
visibility_off Abstract A047: A conserved enhancer locus in ecDNA and HSRs activates MYC transcription in Group 3 Medulloblastoma Jake D. Friske, Flore Cuisin, Paloma Guernalec, Hayden A. Malone, Stephanie Nance, Declan Bennett, Steven Burden, Ti-Cheng Chang, Hao Shi, Justin Williams, Virginia Valentine, Barbara Passaia, B. Ju, Modupeore Adetunji, P. Geeleher, Brian J. Abraham, Gang Wu, Chunliang Li, M. Roussel 2026-03-23 Cancer Research 0 23
visibility_off Targeting extrachromosomal DNA in human cancers. I. Wong, Hyerim Yi, Bruno Melillo, Benjamin F. Cravatt, Howard Y. Chang, P. Mischel 2026-02-03 Nature reviews. Drug discovery 0 19
visibility_off Principles of subclonal gene dosage across human cancer Solrun Kolbeinsdottir, V. Zachariadis, Muyi Yang, Luuk A. Broeils, Christian Sommerauer, Huaitao Cheng, Xinsong Chen, Yingbo Lin, Matias M. Falco, J. Hynninen, S. Hautaniemi, Yizhe Sun, O. Lohi, M. Heinäniemi, S. E. Brage, D. Sarhan, N. Herold, J. Hartman, H. Helgadottir, Felix Haglund de Flon, Anna Vähärautio, Martin Enge 2026-03-18 bioRxiv 0 47
visibility_off The Hidden Mutational Landscape of Extrachromosomal Circular DNA Lali Latsabidze 2026-02-12 Longevity Horizon 0 0
visibility_off Chromosome 3p Deletion Leads to Extensive Genomic Alterations in Diverse Cancers and Confers Synthetic Lethality in Uveal Melanoma. Mitchell C. Cutler, P. B. Howland, M. Hejna, Jun S. Song 2026-02-19 Cancers 0 12
visibility_off Extrachromosomal DNA Detection and Ultrastructural Profiling in Lung and Colorectal Cancer Models Astari Dwiranti, Gina Zulfa Nabila, Tiara Aulia Zalyanti, Shadira Anindieta Irdianto, A. Bowolaksono 2026-03-01 Genes 0 13
visibility_off Deciphering selection patterns of somatic copy-number events Tom L. Kaufmann, Adam Streck, Florian Markowetz, P. van Loo, RF Schwarz 2026-03-03 bioRxiv 0 71
visibility_off Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma S. Garinet, Karl Semaan, Jiao Li, Ze Zhang, Prathyusha Konda, A. Sadagopan, J. Canniff, Noa Phillips, K. Klega, Medha Pandey, H. Savignano, Matthew P Davidsohn, Kevin Lyons, Alessandro Medda, Prateek Khanna, M. Achom, B. Fortunato, Rashad Nawfal, R. El Hajj Chehade, J. O’Toole, J. Horst, D. Freeman, Rachel Trowbridge, C. Chau, William D. Figg, J. Berchuck, Brian D. Crompton, J-H. Seo, T. Choueiri, M. Freedman, S. Baca, S. Viswanathan 2026-02-02 The Journal of Clinical Investigation 1 31
visibility_off PanCNV-Explorer: Deciphering copy number alterations across human cancers Nadine S. Kurz, Kevin Kornrumpf, Anna-Rosa Krüger, Jürgen Dönitz 2026-01-31 bioRxiv 0 15
visibility_off Abstract PS3-04-03: Inter-chromosomal focal amplifications frequently co-carry multiple oncogenes in aggressive breast cancer, accumulating oncogenic elements during breast cancer progression J. Kim, C. HyeongJin, H. Lee, E. Cho, J. Lee, S. Kim, Y. Park, H. Kim 2026-02-17 Clinical Cancer Research 0 9
visibility_off EZH2 Inhibition Restores Tumor Suppressor SFRP1 Activity by Reprogramming Extrachromosomal Circular DNA Dynamics in Ovarian Cancer. Tao Han, Qingya Yan, Yaqi Zhang, Yu Gan, Kaifan Li, Liping Guan, Changqin Jing, Ciqing Yang, Pengfei Li, Bo Gao, Xiang Zhou, Qian Hao 2026-02-15 Biology 0 19
visibility_off Extrachromosomal circular DNA are functional, heritable units that expand genomic plasticity and confer resilience Dana R. MacGregor, Christopher A. Saski 2026-02-25 Frontiers in Plant Science 0 6
visibility_off Decoding the MYC locus reveals a druggable ultraconserved RNA element Peiguo Shi, Feiyue Yang, Fnu Tala, Wesley Huang, Alexis O. Aparicio, Colin H. Kalicki, Aditi Trehan, Michael R. Murphy, Esther Rotlevi, Linqing Xing, Muredach P. Reilly, Jianwen Que, Xuebing Wu 2026-01-30 bioRxiv 0 8
visibility_off Cell Ploidy Modulates Nucleolar Size via Dosage of Nucleolar Organizing Regions Tianhao Bi, Varuni Rastogi, Maged Zeineldin, Blake A. Johnson, Yi Dong, Mulin Li, Tatianna C. Larman 2026-02-16 bioRxiv 0 9
visibility_off Detection of structural DNA variants in medulloblastomas using optical genome mapping Nadezhda Kubon, M. Bălan, David Koppstein, Sophia Praeger, M. Wolter, Peter Ebert, D. Pauck, J. Felsberg, T. Beez, Daniel Picard, Marc Remke, G. Reifenberger 2026-02-11 Acta Neuropathologica Communications 0 47
visibility_off Abstract B021: Single-cell lineage tracing to reveal ecDNA dynamics in glioblastoma through treatment Abigail C. Marshall, A. McKenna 2026-03-23 Cancer Research 0 2
visibility_off BRCA1-A and LIG4 complexes mediate ecDNA biogenesis and cancer drug resistance. Oliver W. Chung, Shun Yao, Ling Wang, Fu Yang, Lauren Schier, M. Aldana, Christian G. Cerda-Smith, Haley M. Hutchinson, Kris C. Wood, Weijia Su, M. Khasraw, Lee Zou, Dale A. Ramsden, Z. Zhang 2026-03-11 Proceedings of the National Academy of Sciences of the United States of America 0 7
visibility_off LINE-1 Transcript Heterogeneity in Non-Small Cell Lung Cancers Is Driven by Host Genomic Context and Conserved Functional Hotspots Yingshan Wang, Kenneth S. Ramos 2026-01-30 Cancers 0 3
visibility_off Detecting Extrachromosomal DNA from Routine Histopathology Muhammad Anwaar Khalid, Michael Gratius, Christopher Brown, Raneen Younis, Zahra Ahmadi, Lukas Chavez 2026-03-02 bioRxiv 0 5
visibility_off High-throughput mapping of spontaneous mitotic crossover and genome instability events with sci-L3-Strand-seq Peter Chovanec, Trevor Ridgley, Yi Yin 2026-02-05 Nucleic Acids Research 1 4
visibility_off Haplotype-resolved reconstruction and functional interrogation of cancer karyotypes. Gregory J. Brunette, R. Tourdot, Jinyu Wang, Darawalee Wangsa, David Pellman, Cheng-Zhong Zhang 2026-03-01 Cell systems 0 30
visibility_off ISPpu10 is a structure-gated bridge RNA recombinase that drives safe, large-scale genomic plasticity Xue-Mei Na, Bai-Tao Chen, Han Liu, Yi-Tong Lin, Yuan Yuan, Tai Chen, Yi Xiong, Yu-Hang Zhang, Nan Yang, Fei Zhu, Yingying Zhang, Ximin Chi, Zhiyou Zong, Chen Ling 2026-03-20 bioRxiv 0 15
visibility_off Abstract A050: Mutant allele copy number gains define distinct molecular subtypes of oncogene-driven cancers and are associated with response to allele-specific KRASG12C inhibitor sotorasib in NSCLC Maria A. Perry, Allison L Richards, Adam Price, Sam E. Tischfield, H. Walch, Helen Xie, Ariaki Dandawate, K. Pichotta, Christopher Fong, J. Jee, N. Schultz, R. Thummalapalli, H. Yu, P. Chi, Anupriya Singhal, Wungki Park, E. O’Reilly, Y. Murciano-Goroff, Mark M. Awad, R. Yaeger, K. Arbour, M. T. Donoghue, Michael F. Berger, C. Bandlamudi 2026-03-05 Cancer Research 0 64
visibility_off A structure-selective endonuclease drives uniparental mitochondrial DNA inheritance Mayu Shimomura, Hwa Young Yun, P. Zuzarte, Jared T. Simpson, Haley D M Wyatt, T. Hurd 2026-03-20 bioRxiv 0 6
visibility_off A distal CTCF-binding site drives MYC expression plasticity in a negative feed-forward loop Chenyin Gao, M. Martino, Ayushi Chaurasiya, F. Casagrande, Jia Pei Lim, Yuri S. van Ekelenburg, W. Feng, Yan Liu, Barbara A. Scholz, Pragyan Mishra, Mallikarjuna Thippana, Dennis Torkornoo, Phong KC Chau, Rabia Khan, T. Tannaes, I. Tzelepis, Ilyas Chacoua, Natalie Geyer, S. Meltzer, A. H. Ree, Marco Gerling, Johan Hartman, N. Kiani, Rolf Ohlsson, A. Göndör 2026-01-31 bioRxiv 0 31
visibility_off Insertional activity of human Alu and L1 retrotransposons is associated with DNA repair pathways and genome instability in cancer M. Suntsova, Aleksander Modestov, Elizaveta Rabushko, Nikolai Komarov, I. Gaziev, Anastasia Novosadskaya, Anastasiya Barysionak, G. Zakharova, N. Shaban, Anna Khristichenko, Anna A. Emelianova, Marianna A. Zolotovskaia, E. Poddubskaya, A. Seryakov, Anton Buzdin 2026-02-07 Computers in biology and medicine 1 22
visibility_off Unleashed condensation by recurrent mutations of an epigenetic regulator promotes cancer Yansu Song, Yi Hao, Maria Latacz, Marta Cykowiak, Julia Kirylczuk, Xuebo Quan, Francesco Palomba, Songwei Ni, Linjie Liu, Jing Hu, Bi-Wei Shi, Ammon E. Posey, Qiaoli Li, Haoran Yuan, Jie Sun, R. Pappu, M. Digman, Kai Huang, Hao Jiang 2026-02-20 bioRxiv 0 84
visibility_off Hi-C for genome-wide detection of enhancer-hijacking rearrangements in routine lymphoid cancer biopsies. Jamin Wu, Shih-Chun A. Chu, Jang Cho, Misha Movahed-Ezazi, Kristyn Galbraith, C. Fang, Yiying Yang, C. Schroff, Kristin Sikkink, M. Perez-Arreola, Logan Van Meter, Savanna Gemus, Jon-Matthew Belton, Xue Song, Aishwarya Gurumurthy, Hong Xiao, V. Nardi, A. Louissant, Raju K Pillai, Joo Y. Song, D. Shasha, A. Tsirigos, A. Perry, N. Brown, Tatyana Gindin, Lina Shao, Marcin Cieslik, Minji Kim, Anthony D Schmitt, M. Snuderl, R. Ryan 2026-02-01 Cell genomics 0 64
visibility_off It’s a kind of MAGIC: uncovering the origins of chromosomal instability D. Gómez-Peregrina, César Serrano 2026-02-05 Signal Transduction and Targeted Therapy 0 5
visibility_off Chromosomal instability and chromosome 17p loss drive convergent NDE1 synthetic lethality in metastatic cancer cells Caroline M. Teddy, Jacob P. Hoj, Julia D Caci, Min Lu, Shane T. Killarney, Tal Ben-Yishay, U. Ben-David, Kris C. Wood 2026-02-12 bioRxiv 0 17
visibility_off Diverse Mechanisms of Smarcb1 Inactivation and Genome Maintenance Defects in Ultra-Rare Malignant Rhabdoid Tumors Elizabeth Rasmussen, Elena Mironova, Zhao Lai, K. Maaß, S. Volz, Dias Kurmashev, Stefan M. Pfister, Yidong Chen, R. Kurmasheva 2026-03-02 bioRxiv 0 77
visibility_off Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis. Sonia Zumalave, Martín Santamarina, Nuria P Espasandín, Jorge Zamora, Daniel García-Souto, J. Temes, Toby M. Baker, Jorge Rodríguez-Castro, P. Otero, Ana Pequeño-Valtierra, Iago Otero, Ana Oitabén, Eva G. Álvarez, Iria Díaz-Arias, Mónica Martínez-Fernández, M. Blanco, P. van Loo, G. Cristofari, Bernardo Rodriguez-Martin, J. Tubío 2026-02-26 Science 0 71
visibility_off Aurora kinase A is a synthetic lethal target in FANCA-deficient cancers Dilara Akhoundova, Martín González-Fernández, Aavash Baral, Andrej Benjak, Carmen Perry, Dinda Shezaria Hardy Lubis, Ladina Hörtensteiner, Saskia Hussung, Lea Lingg, S. Maletti, Aino Paasinen-Sohns, Marika Lehner, B. Dislich, E. Vassella, Simone de Brot, Therese Waldburger, Petros Tsiridis, C. Cardozo, Ralph Fritsch, C. Pistoni, Seynabou Diop, Phillip Thienger, Taina S. Kaiponen, Muriel Jaquet, Mariana Ricca, S. Sivakumar, Christopher McDermott-Roe, David E. Root, P. Francica, Sven Rottenberg, M. Rubin 2026-02-06 bioRxiv 0 21
visibility_off Genomic and Evolutionary Determinants of Two-hit Frequencies in Tumor Suppressor Genes Nivedita Mukherjee, R. Sabarinathan 2026-02-18 bioRxiv 0 1
visibility_off A Translocation within the Ogataea Species Complex Alters Local Subtelomeric Chromatin while Maintaining Overall Genome Organization Tiffany J. Lundberg, Nickolas M. Lande, Daniel Tourevski, Riley Figueroa, S. Hanson, Andrew D. Klocko 2026-03-07 bioRxiv 0 14
visibility_off SMAD4 loss drives chromosomal instability during tumourigenesis via translational reprogramming Julia V. Milne, Kameng Wu, Eric P. Kusnadi, S. Brosda, Kenji M. Fujihara, Ebtihal H. Mustafa, S. Witts, Katherine Papastratos, Maree Pechlivanis, A. Trigos, M. Jana, Paul J McMillan, Thomas D. Jackson, N. Thio, Yuzhou Feng, K. Montgomery, J. Alexander, Mark Wade, A. P. Barbour, Kaylene J. Simpson, C. Duong, David S Liu, Wayne Phillips, Luc Furic, N. Clemons 2026-03-25 bioRxiv 0 21
visibility_off Molecular heterogeneity of HPV-associated cancers and strategies to overcome treatment resistance Sara Rasouli, Weiyi Gong, Raegan Wood, Danyal Daneshdoust, Anam Khan, Rani Mahyoob, Chongwen Cao, Zihao Yu, N. Putluri, Gennady Shvets, Haichang Li, Bo Zhao, Xuefeng Liu, Jenny Z Li 2026-03-01 Cancer Heterogeneity and Plasticity 0 54
visibility_off Elevated YBX1 mRNA expression is associated with a genomically unstable and clinically aggressive cancer state: a pan-cancer analysis Selena Wang, Zahra Shafaei Pishabad, D. Sarkar, A. Bhandarkar, Makhdoom Sarwar, Aaron Jeffs, Glen Reid, Antony Braithwaite, S. Mehta 2026-03-23 bioRxiv 0 6
visibility_off Mitotic microhomology-mediated break-induced replication promotes chromoanasynthesis. Greg H P Ngo, K. Cleal, Sara Seifan, Vanda Miklós, Szymon A. Barwacz, B. Ruis, Siamak A Kamranvar, Julia W. Grimstead, Ying Liu, Eric A. Hendrickson, D. M. Baird 2026-03-03 Nature communications 0 15
visibility_off Comprehensive detection of genetic and epigenetic alterations in cancer using long reads with TumorLens L. F. Paulin, M. Shi, Y. Fu, X. Zheng, G. Au-Yeung, D. Bowtell, J. Chen, Y. Liang, C. Hammer, F. Sedlazeck 2026-03-19 medRxiv 0 34
visibility_off A context dependent hierarchy of APOBEC3A and APOBEC3B mutators in lung adenocarcinoma Josefine Striepen, Luka Culibrk, Alexandra Dananberg, Jacob S. Rozowsky, Mia Petljak, J. Maciejowski 2026-03-11 bioRxiv 0 24
visibility_off Diversity and Genomic Organization of Non-B DNA Motifs in Haplotype-Resolved Human Genome Assemblies Alexander Turco, Nadejda B. Boev, Sushant Kumar 2026-03-07 bioRxiv 0 1
visibility_off Abstract PR011: Breakage of chromosome 3p initiates clear cell renal cell carcinoma evolution Rashmi Dahiya, Ianthe Van. Belzen, Chengheng Liao, Yu-Fen Lin, Emilija Aleksandrovic, Angad Kumar, Ahyeon Ko, J. Brugarolas, Siyuan Zhang, Qing Zhang, I. Cortés-Ciriano, Peter Ly 2026-03-13 Cancer Research 0 59
visibility_off Centrosome architecture and m6A-dependent gating of p53 surveillance after whole-genome doubling D. Migliorati, Alessia Mattivi, Gian Mario Moretta, Selene Tessadri, Nicole Cona, Giorgia Pellizzaro, M. Pancher, Mattia Furlan, L. Coscujuela, Martin Wegner, Marine. H. Laporte, M. Libergoli, Feryel Soualmia, Stefano Biressi, T. Tebaldi, A. Quattrone, A. Inga, E. Jacotot, V. Hamel, Paul Guichard, Mattia Pelizzola, M. Kaulich, M. Burigotto, Luca L. Fava 2026-02-25 bioRxiv 0 35
visibility_off Cell confinement initiates a delayed but heritable loss of chromosomes Steven H. Phan, Mai Wang, Kayla R. Snare, Jonah Kandell, Jeneille S. Deans, P. Rompolas, Guilherme P F Nader, D.E. Discher 2026-02-03 bioRxiv 0 26
visibility_off The pan-tumor landscape of gene amplifications and copy number amplification ratio for established and emerging clinical targets. Jessica K. Lee, J. Quintanilha, Kuei-Ting Chen, Bernard Fendler, C. Tambaoan, R. Graf, Nicole Odzer, L. Pusztai, Maryam B. Lustberg, Harshabad Singh, Matthew R Strickland, Tess A O'Meara, S. Tolaney, T.A. Yap, J. Ross, A. Gasco Hernandez, Brennan Decker, Richard S P Huang, S. Klempner, E. S. Sokol, Alexa B Schrock 2026-03-23 Clinical cancer research : an official journal of the American Association for Cancer Research 0 50
visibility_off Topological Regulation of the Mammalian Genome by Positive DNA Supercoiling A. K. Singh, Luis Altamirano-Pacheco, Lieng Taing, A. Dubois, Pablo Navarro 2026-03-10 bioRxiv 0 12
visibility_off Overexpression of SOX3 due to an X chromosome inversion leading to ovotesticular difference in sex development Carolina Gama Nascimento-Vidoti, H. Fabbri-Scallet, M. Guaragna, Melissa Bittencourt de Wallau, Vanessa Sodré de Souza, S. S. da Costa, A. Krepischi, J. Mazzeu, C. M. Carvalho, A. Maciel-Guerra, Gil Guerra-Junior, T. P. Vieira 2026-02-12 Biology of Sex Differences 0 25
visibility_off DeepECC: a deep learning framework for genome-wide identification and analysis of human cancer eccDNAs. Changcheng Wang, Yisen Xu, Rufeng Li, Min Qiang, Chen Guo, Qian He, Xiaokang Wu, Lingmi Hou, Qiuran Xu, Yungang Xu 2026-02-24 Nucleic acids research 0 18
visibility_off Abstract PR005: KRAS amplification as de novo oncogenic alteration and therapeutic target in human cancers Mark M. Awad, B. Ricciuti, S. V. Michelina, E. Garbo, P. Tarantino, A. Tewari, Igor Odintsov, Xinan Wang, Cassio Murilo Trovo Hidalgo Filho, N. Gandhi, Kenneth L. Kehl, G. Lamberti, A. Di Federico, Malini M Gandhi, Federica Pecci, Mihaela Aldea, V. Santo, E. Gariazzo, L. Sholl, S. Scalera, Marcello Maugeri, Nancy Lin, F. Cappuzzo, P. Janne, Steven Ressler, M. Capelletti, Alexa B Schrock, T. Choueiri, Julie Wiese, Debbie Liao, S. Kasibhatla, S. Tolaney, A. Aguirre, Alice A Shaw, Chiara Ambrogio 2026-03-05 Cancer Research 0 90
visibility_off Repetitive DNA shapes genome architecture and chromosomal diversification in birds of prey Guilherme Mota Souza, J. A. D. Vidal, G. Toma, Rafael Kretschmer, E. D. de Oliveira, Thomas Liehr, M. Cioffi 2026-03-05 bioRxiv 0 32
visibility_off Transposable element–gene chimera cartography, origination and role in enhancing transcriptome plasticity Y. Cheon, E. Alvstad, Denis Torre, D. Quach, Jennifer Nguyen, K. Hyun, Ming Zhou, Tianxiong Yu, Liang Liu, Yoseop Yoon, Fairlie Reese, Lauren Faraone, Yingcong Li, F. J. Arnold, Yesai S. Fstkchyan, Uttiya Basu, E. Kvon, E. M. Valente, J. Ho, Minji Byun, Ernesto Guccione, Yongsheng Shi, Zhiping Weng, Marcus M. Seldin, Ivan Marazzi 2026-02-25 Nature Structural & Molecular Biology 0 28
visibility_off Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types Andrew Everall, Avraam Tapinos, A. Hawari, A. Cornish, Amit Sud, D. Chubb, B. Kinnersley, A. Frangou, Miguel Barquin, Josephine Jung, David N. Church, Ludmil B. Alexandrov, R. Houlston, Andreas J. Gruber, D. Wedge 2026-02-13 Nature Genetics 1 74
visibility_off Determinants of chromosomal rearrangements in holocentric Leptidea butterflies Filip Thörn, Jean-Loup Claret, N. Backström, Jesper Boman 2026-02-27 bioRxiv 0 27
visibility_off Integrative Multi-Omics Analysis Identifies a Functional Enhancer Driving Tumorigenesis in Head and Neck Squamous Cell Carcinoma Pengfei Xu, Xiaorong Liu, J.J. Pu, Xiaoling Lu, Victor H. F. Lee, Evelyn Wang, Qianhui Jiang, Dan Yu, Bin Yan, Jinlin Song, Qi Zhong, Ping Yang, Nhan L. Tran, Xinyuan Guan, Yu-xiong Su, Junwen Wang 2026-02-05 bioRxiv 0 5
visibility_off Non-B DNA structures and their contributions to genetic diversity, aging, and disease Eleftherios Bochalis, Irene Dereki, Guliang Wang, Argyro Sgourou, Karen M. Vasquez, IIias Georgakopoulos-Soares 2026-02-05 Nucleic Acids Research 1 27
visibility_off BAP1 loss impairs Non-Homologous End Joining DNA repair promoting genomic instability Sabrina Caporali, C. Schuy, Melanie Rall-Scharpf, Alessio Butera, Lisa Wiesmüller, Ivano Amelio 2026-02-18 bioRxiv 0 11
visibility_off A unified model of aneuploid karyotype dynamics M. Hénault, Lisa M. Wood, L. Heasley 2026-02-20 bioRxiv 0 9
visibility_off Defective BRCA1-mediated DNA end resection drives tandem duplication formation and FANCM synthetic lethality Namrata M. Nilavar, Alberto Marin-Gonzalez, F. Menghi, D. Nguyen, Nicholas A. Willis, E. Wientjens, Bing Xia, Jos Jonkers, Edison T. Liu, Ralph Scully 2026-02-20 bioRxiv 0 21
visibility_off SETDB1/ATF7IP regulate the precise genome engineering of HUSH-regulated genes B. Ruis, Henry N. Ward, Chad L. Myers, A. Bielinsky, Eric A. Hendrickson 2026-02-09 Epigenetics & Chromatin 0 29
visibility_off Microhomology-Mediated Tandem Duplication Drives Tandem Repeat Formation Across Life Xianfang Wei, Wanxin Gong, Yi-jun Zheng, Jing Zhang, Xianyuan Wei, Chen Peng, Xiangwei He, Chao Jiang 2026-03-02 bioRxiv 0 23
visibility_off Multiplexed TrAEL-seq captures DNA replication dynamics in mammalian cells Neesha Kara, Laura Biggins, Alex J. Whale, Kieron May, V. Grinkevich, Paola Garran-Garcia, Jhanavi Srinivasan, P. Rugg-Gunn, Claudia Ribeiro de Almeida, Samantha J Walker, G. Picco, Mathew J. Garnett, Simon Andrews, Aled J. Parry, Helen M R Robinson, J. Houseley 2026-02-24 Nucleic Acids Research 0 14
visibility_off Extrachromosomal DNA in urothelial carcinoma: mechanisms and clinical applications. Conghui Li, Zhiqiang Hu, Weimin Zhang, Y. Ji, Fubing Wang, Yuchen Zeng, Sanju Sinha, Fengbiao Mao, Chunhua Lin, Wei Lv 2026-03-19 Nature reviews. Urology 0 26
visibility_off Novel driver gene MDC1 confers homologous recombination repair deficiency and genomic instability in chemoresistant relapsing ovarian cancer. Michael A. Diaz, Nicole Gull, Pei-Chen Peng, Kruttika Dabke, J. Baker, Jennifer Sun, J. Alvarado, Benjamin Bastin, Nimisha Mazumdar, C. Santiskulvong, Andrew J. Li, Beth Y. Karlan, B. Rimel, Sarah Parker, S. Gayther, Michelle R. Jones 2026-03-06 Journal of translational medicine 0 85
visibility_off Genome-wide discovery of cis-regulatory elements in a large genome G. Forbes, Emilia Skafida, Irene Karapidaki, Savannah Moinet, Mowgli Dandamudi, Çağrı Çevrim, F. Momtazi, Chryssa Anastasiadou, S. Lo Brutto, M. Averof, Mathilde Paris 2026-03-19 bioRxiv 0 33
visibility_off p53 restoration suppresses retrotransposon-driven chromosomal instability through nonlinear let-7 feedback and stochastic burst control Dr. L. Boominathan 2026-03-02 bioRxiv 0 0
visibility_off Transposable elements as drivers of genome evolution in Drosophila virilis A. Rezvykh, Dina A Kulikova, E. Zelentsova, Liudmila Protsenko, Alina V Bespalova, Iuliia O Guseva, J. Blumenstiel, M. Evgen'ev, S. Funikov 2026-02-05 Nucleic Acids Research 0 21
visibility_off EBNA1 INHIBITORS REVEAL CDC7 AND POU2F1 AS DIRECT FUNCTIONAL TARGETS IN EBV EPITHELIAL CANCERS Songtao He, Niseno Terhuja, Samantha S. Soldan, Christopher Chen, Joel Cassel, Xiangfan Yin, Qin Liu, Sun Sook Chung, L. J. Castro-Muñoz, Leena Yoon, Jie Wang, Joseph M. Salvino, B. Gewurz, I. Tempera, T. Messick, Paul M. Lieberman 2026-02-05 bioRxiv 0 36
visibility_off A Cre-mediated copy number variant compromises the reliability of a LoxP-STOP-LoxP-PLAG1 driven brain tumor model Jan Vaillant, Sangita Pal, Jan Müller, A. Wittmann, Akosua Boakye-Yiadom, P. Sievers, P. Zimmer, Melanie Schoof, F. Schelb, Nina Hofmann, Michaela-Kristina Keck, Tessa Fabian, U. Schüller, Marc Zuckermann, R. Beroukhim, P. Bandopadhayay, David T. W. Jones, L. Kutscher 2025-12-09 Neuro-Oncology Advances 0 151
visibility_off RNF8 over-expression promotes genomic instability in aggressive breast cancer Iván Anduro-Corona 2026-01-30 Biotecnia 0 0
visibility_off Mutational signatures in cancer genomes alter protein sequence motifs in cellular signaling networks Jigyansa Mishra, M. Bayati, Zoe P. Klein, K. Cheng, Omar M. Wagih, Nina Adler, Maria Farina-Morillas, A. Bahcheli, J. Reimand 2026-02-05 bioRxiv 0 48
visibility_off A centromere but not just a centromere: structure and evolution of a selfish chromosomal supergene in monkeyflowers Evan R. Stark-Dykema, Findley R. Finseth, Will Conner, L. Fishman 2026-02-23 bioRxiv 0 34
visibility_off Rapid chromosomal evolution and oligocentromeric drive in sedges and rushes James McCulloch, Marcela Uliano-Silva, C. Wright, Ian R. Henderson, Sam Ebdon, K. Jaron, Mark L. Blaxter 2026-03-02 bioRxiv 0 13
visibility_off A single-cell atlas linking intratumoral states to therapeutic vulnerabilities across cancers María González-Bermejo, Laura Serrano-Ron, Santiago García‐Martín, Óscar Lapuente-Santana, Ignacio Sanz Portillo, Pablo González-Martínez, G. Gómez-López, Fátima Al-Shahrour 2026-02-19 bioRxiv 0 9
visibility_off Localised negative feedback shapes genome-wide patterning of meiotic DNA breaks Luz María López Ruiz, J. A. Harper, Dominic Johnson, Rachal M. Allison, William H. Gittens, George G. B. Brown, Tim J. Cooper, Valerie Garcia, Matthew J. Neale 2026-02-24 bioRxiv 0 23
visibility_off Centromeres are hotspots of cytosine methylation epimutations in a filamentous fungus Mariana Villalba de la Peña, Clayton Hull-Crew, Taylor R. Hutter, Cynthia A. Vino, Peter Sarkies, Maria Colomé-Tatché, F. Johannes, Andrew D. Klocko, Ilkka Kronholm 2026-03-05 bioRxiv 0 14
visibility_off Abstract PS3-06-19: Phylogenetic and Transcriptomic Analyses Reveal Specific Adaptations for Progression of Breast Cancer M. Russo, P. Raj-Kumar, J. Liu, A. Praveen-Kumar, A. Kovatich, A. Tan, H. Hu, C. Shriver, X. Lin 2026-02-17 Clinical Cancer Research 0 6
visibility_off A sequence motif for DNA double-strand break and telomere healing during programmed DNA elimination Jansirani Srinivasan, Marro Agbaga, Vincent Terta, Brandon Estrem, James R. Simmons, Ryan Oldridge, Mehwish Iftikhar, Abigail West, Han K. Lam, T. C. Dockendorff, Jianbin Wang 2026-03-09 bioRxiv 0 18
visibility_off CHD4 epigenetically coordinates genomic instability and immunosuppression to drive pan-cancer progression and confer HDAC inhibitor sensitivity Guangxu Fu, Yong Tao, Keyi Feng, Yuxing Chen, Wen Zhang, Zhen Zhang, Guoda Hu, Yunsheng Ou 2026-02-13 Clinical and Experimental Medicine 0 7
visibility_off Epigenetic Deregulation of Transposable Elements Links Developmental Processes and Tumorigenesis Chi F Lynch-Sutherland, Peter Stockwell, Aniruddha Chatterjee, Michael R. Eccles, Erin C. Macaulay 2026-03-01 International Journal of Molecular Sciences 0 11
visibility_off Substantial genomic and methylation variability between MCF-7 sublines H. Atanda, Adam D Ewing 2026-02-19 bioRxiv 0 4
visibility_off Abstract PD3-04: Chromatin remodelling is involved in resistance to CDK4/6 inhibitors in ER+ breast cancer F. Pepe, F. Messina, F. Napolitano, G. Nassa, A. Salvati, D. Memoli, C. Fierro, D. Esposito, S. Belli, C. Ascione, G. Attanasio, A. Vallefuoco, A. Benish, L. Formisano, R. Bianco, A. Servetto 2026-02-17 Clinical Cancer Research 0 16
visibility_off Real-World Prevalence and Structural Validation of the Canonical 9p21 MTAP–CDKN2A/B Deletion in Non-NSCLC Solid Tumors Miran Han, Eunbyeol Lee, J. Shin, Minsuk Kwon, Jung Yong Hong, Seung-Tae Kim, Soomin Ahn, Kyoung-Mee Kim, J. Lee, S. Lim 2026-03-01 Cancers 0 32
visibility_off Fully T2T pedigree assemblies reveal genetic stability and epigenetic plasticity of human centromeres across inheritance and cell-fate transitions Shihua Dong, Xiaoyun Xing, Monika Cechova, Hailey Loucks, Selvamani Vijayalingam, Amber Neilson, M. Sentmanat, Juan Macias, Tianjie Liu, Z. Dong, Benpeng Miao, Wenjin Zhang, Chad Tomlinson, Heather Schmidt, Edward A. Belter, Ming Hu, Xiaoxia Cui, N. Stitziel, K. Miga, Ting Wang 2026-02-17 bioRxiv 0 45
visibility_off Evolutionary constraints on RNA polymerase gene positioning in the genome of fast-growing bacteria Leticia Larotonda, Elisa Ojeda, Noa Guzzi, M. B. Bordignon, F. Fulgenzi, D. Comerci, Briardo Llorente, Didier Mazel, C. Loot, Marie-Eve Val, A. Soler-Bistué 2026-02-24 Nucleic Acids Research 0 28
visibility_off TERT drives liver tumorigenesis beyond telomere elongation Laura Braud, Julien Vernerey, Arnaud Guille, Pierre Cordier, Clémence Ginet, Tom Egger, Manuel Bernabe, D. Churikov, Quentin Da Costa, Aïda Meghraoui, C. Desdouets, Ling Gu, F. Bertucci, Christophe Lachaud, Vincent Géli 2026-02-09 bioRxiv 0 21
visibility_off Fragmenting the future with FLARE: a comprehensive fragmentomics pipeline based on long-read nanopore sequencing M. Ficorilli, Marta Lucchetta, Deborah Lenoci, Ilenia Rolli, Nicole Farina, V. Cristofaro, L. Giannini, A. Ottini, A. Deganello, S. Cavalieri, L. Licitra, L. De Cecco 2026-03-13 Frontiers in Genetics 0 22
visibility_off “Landscape of 8q24.3-Encoded microRNAs and Their Prognostic Impact in Ovarian Cancer” Kamil Filipek, I. Merelli, F. Chiappori, Marianna Penzo 2026-03-11 bioRxiv 0 4
visibility_off NUP85 as a Pan-Cancer Immune Biomarker: Integrated Multi Omics and Functional Analyses Reveal Its Role in Tumor Prognosis Weihao Kong, Yingqi Hu, Kangjie Zhang, Zhipeng Zhu, Yajun Zou, Long Teng, Xingyu Wang, Jianlin Zhang 2026-03-01 ImmunoTargets and Therapy 0 12
visibility_off Isolated signals in BCL2, MYC, BCL6, and DDIT3 FISH: implications for genetic alterations and protein dysregulation Z. Wei, Qiuyue Chen, Zhenbo Feng, Fang Tang 2026-02-11 Pathology and Oncology Research 0 1
visibility_off From Gene Knockouts to Genome Remodeling: Large DNA Fragment Deletion Technologies in Plants Jiayi Hou, Hui Li, Feng Zhang, Dan Yang, Yan Xiong, Xiaoyue Zhu, Mingzhang Wen 2026-03-01 Plants 0 21
visibility_off POLQ promotes tumor progression and immunosuppression via ATM-P53 signaling in endometrial cancer Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, K. Tang, Lei Gong, Yi Hu 2026-03-11 Oncology Reports 0 6
visibility_off N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletion Xiaodong Li, Sarah Allen, Li-Yang Lyu, Sebastian Bechara, Cristina Engeroff, Alan Hendrick, M. Nowacki 2026-02-16 bioRxiv 0 29
visibility_off Comparative centromere genomics reveals evolutionary divergence in Solanaceae genomes. Penglong Wan, Ming Hu, Hongyu Jin, Shuyuan Tang, Min Zhong, Jiaowen Cheng, Zhangsheng Zhu, B. Cao, Guoju Chen, Changming Chen, Chengjie Chen, Jianwen Song, Yi Liao 2026-03-11 Genome biology 0 25
visibility_off A CDCA2-MYC positive feedback loop controls cancer cells survival. Konstantinos Stamatiou, Lorena Ligammari, Malki Bothota, Antonia Tsavou, Ezgi Gokhan, Ylenia Cicirò, M. Zacarías, Laura Soucek, Arturo Sala, Paola Vagnarelli 2026-03-11 Open biology 0 6
visibility_off DNA secondary structures in BCL2 and MYC elicit activation-induced cytidine deaminase binding and activity Mason McCrury, Ambrocio Sanchez, Rylie Mangold, Todd J Spears, Claire Doshier, Rémi Buisson, M. Miah, Derin Akdeniz, S. Kendrick 2026-02-24 Nucleic Acids Research 0 15
visibility_off Zeste White 10 May Serve as a Prognostic Biomarker and Therapeutic Target for Human Breast Cancer S. F. Bellah, Md. Alim Hossen, S. Billah, Olanrewaju Ayodeji Durojaye, Md. Obayed Raihan 2026-03-01 Breast Cancer : Basic and Clinical Research 0 11
visibility_off Single-nucleus multi-omics delineates distinct epigenetic programs associated with tumor progression in lung adenocarcinoma. Yeji Kim, Huiram Kang, Y. Hwang, Kyung Soo Kim, S. Moon, Jeonghan Kim, Seung Joon Kim, Hae-Ock Lee 2026-02-11 Clinical epigenetics 0 8
visibility_off HSP90 inhibition disrupts telomere maintenance and promotes chromosomal instability (CIN) in cancer cells Hee-Sheung Lee, Jung-Hyun Kim, Mikhail Liskovykh, Neckers Len, N. Kouprina, Vladimir Larionov 2026-02-11 Research Square 0 36
visibility_off Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer Sarah Preston-Alp, Yin Wang, Matteo Bergonzoni, A. Kossenkov, Samantha S. Soldan, L. B. Caruso, Davide Maestri, Paul M. Lieberman, B. Gewurz, I. Tempera 2026-02-10 mBio 0 36
visibility_off Gene Amplification in Rhabdomyosarcoma: Lessons from a Rare Cancer. Frederic G Barr 2026-03-06 International journal of molecular sciences 0 2
visibility_off The Circular DNA Size Code Zurab Abashidze 2026-01-31 Longevity Horizon 0 0
visibility_off The precision strategy of human genome correction via a set of circular donor DNA and its cleaver Kohji Kusano, Kaoru Takizawa, Jitsutaro Kawaguchi, I. Hara, Toyotaka Mori 2026-03-11 Frontiers in Genome Editing 0 15
visibility_off TFU72 is a novel and potent DNA-PKcs inhibitor for enhancing homology-directed repair gene editing Sridhar Selvaraj, Ludwig Schmiderer, Jacob Lamberth, Thomas Fuchss, Freja K. Ekman, Norman F. Russkamp, M. Porteus 2026-03-11 bioRxiv 0 7
visibility_off Abstract B043: Defective lipid homeostasis drives nuclear envelope disruption and genomic instability during gliomagenesis Yinglu Guan, Kaylene J. Lu, Ece Kilinc, Takashi Shingu, Mingxin Li, Jian Hu 2026-03-23 Cancer Research 0 4
visibility_off The nuclease EXO1 promotes genomic instability by degrading nascent DNA in BRCA-proficient cells. Alexandra Nusawardhana, Claudia M. Nicolae, George‐Lucian Moldovan 2026-02-25 Nature communications 0 32
visibility_off Nuclear DNA of plastid origin (NUPTs), neglected driver of genome variation and evolutionary innovation Lorenzo Carretero-Paulet, Juan Pablo Marczuk-Rojas, Aaron Gálvez-Salido 2026-02-01 The Plant Journal 0 4
visibility_off Stable but turbulent: the two faces of the germline-restricted chromosome of passerine birds S. A. Schlebusch, Z. Halenková, H. Moreno, J. Rídl, O. Kauzál, A. Suh, K. Janko, D. Dedukh, J. Pačes, T. Albrecht, R. Reifová 2026-02-18 bioRxiv 0 15
visibility_off Unravelling genome-wide mosaic microsatellite mutations at single-cell resolution Chunyi Wang, Wenxuan Fan, Weixiang Wang, Yonghe Xia, Jinhong Lu, Xiaoyu Ma, Jichuan Yu, Yunchao Zheng, Yan Luo, Wenlong Li, Qing Yang, Meizhen Lin, Huan Liu, Yangning Lan, Chengyu Li, Xiaodong Liu, Danyang He, Shang Cai, Xiuyan Yu, Dan Zhou, M. Kellis, Xushen Xiong, Qi Xie, Yanmei Dou 2026-02-06 bioRxiv 0 45
visibility_off Structure and genomic organization of the human DUX4 homologue bovine DUXC B. Yaşar, T. Org, M. Ivask, G. Yazgeldi Gunaydin, N. Boskovic, Ü. Jaakma, J. Kere, A. Kurg, S. Katayama 2026-03-07 bioRxiv 0 32
visibility_off Canonical and Noncanonical Forms of G4 DNA at the Cluster III of BCL6 Breakpoint Region Could Lead to Chromosomal Translocation in DLBCL. Saniya M. Javadekar, Sayak Das, Sujatha M. Hanumegowda, Susmita Kumari, B. Choudhary, S. Raghavan 2026-03-01 The Journal of biological chemistry 0 47
visibility_off Rapid genome modifications including chromosomal fusions and large-scale inversions are key features in Arctic codfish species S. Hoff, Marius F. Maurstad, O. K. Tørresen, R. Araya, Paul R. Berg, K. Præbel, K.S. Jakobsen, S. Jentoft 2026-02-16 Genome Biology 0 40
visibility_off APOBEC3B regulates HPV replication by inducing R-loop formation and DNA damage. Conor W Templeton, Jasmine S Gulik, Lou Laimins 2026-03-23 PLoS pathogens 0 4
visibility_off CO15 | Optical genome mapping identifies multiple structural variation and catastrophic rearrangements in B-cell prolymphocytic leukemia R. Maffei 2026-03-03 Haematologica 0 28
visibility_off TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness. Yining Tao, Qi Zhang, Haoyu Wang, Binghui Yang, Haoran Mu, Kaiyuan Liu, Weisong Zhao, Xiyu Yang, Bowen Zhao, D. Zuo, Liu Yang, Zhengdong Cai, Zongyi Wang, Hongsheng Wang, Yingqi Hua, Wei Sun 2026-01-30 Cancer research 0 24
visibility_off Ultrasensitive and Rapid Screening of Tumor-Associated Extrachromosomal Circular DNA by Selective Real-Time Rolling Circle Amplification. Yiran Liu, Gang Li, Jing Zheng, Qing Li, Wei-Min Tong, Weiyi Lai, Hailin Wang 2026-02-03 Analytical chemistry 0 15
visibility_off Hemizygous loss of helicases promotes genomic instability and cancer development. Karolin Voßgröne, F. Favero, Krushanka Kashyap, F. G. Rodríguez-González, A. Olsen, Xin Li, Balca R. Mardin, J. Weischenfeldt, Claus S. Sørensen 2026-02-20 Science advances 0 19
visibility_off RARRES1 marks an immune-cold, chemoresistance-associated malignant epithelial subpopulation enriched in pancreatic ductal adenocarcinoma Heming Ge, Jing Zhou, T. Ghadban, G. Wolters-Eisfeld, T. Hackert, Dan Wang, Wenxue Liu, C. Güngör 2026-03-19 Cancer Immunology, Immunotherapy : CII 0 19
visibility_off DNA polymerase kappa stabilized by Ptbp2 interacts with MRE11 and promotes genomic instability in leukemia Shristi Lama, Bibhudev Barik, Sajitha Is, Tannistha Sarkar, Sayantan Chanda, Monalisa Behera, Payel Guha, Subhankar Priyadarshi Behera, S. Biswas, Sonali Mohapatra, G. Biswas, Soumen Chakraborty 2026-02-10 Cell Death Discovery 0 4
visibility_off Identification of LncRNAs scaffolding a chromatin-associated gene regulatory complex in breast cancer cells comprising ERα, DOT1L and menin Viola Melone, A. Salvati, L. Palo, Domenico Palumbo, D. Memoli, M. Ianniello, Mehrnoush Nikzaban, Aurora Casaburi, J. Lamberti, Francesca Rizzo, Alessandro Weisz, G. Nassa, Roberta Tarallo 2026-01-30 Cell Communication and Signaling : CCS 0 33
visibility_off Abstract PS2-12-09: Global expression of small DNA damage-associated RNAs (sdRNAs) in breast cancers D. DeConti, J. Yu, S. Warhadpande, Fieda Abderazzaq, A. Desbuleux, E. Hatchi, J. Rosenbluth 2026-02-17 Clinical Cancer Research 0 12
visibility_off Spatio-Temporal Landscape of Whole-Genome DNA Methylation Patterns in Ovarian Cancer G. Marchi, K. Lavikka, Y. Li, V. Isoviita, G. Micoli, D. Afenteva, E. Pöllänen, S. Holmström, A. Häkkinen, E. Valkonen, I. Maarala, J. Astren, C. Facciotto, F. Dietlein, S. Hietanen, T. Muranen, J. Oikkonen, J. Hynninen, A. Virtanen, A. Lahtinen, S. Hautaniemi 2026-03-25 None 0 7
visibility_off Functional Annotation of the Major Histocompatibility Complex Locus Lexi R. Bounds, Alejandro Barrera, Maria A. ter Weele, Siyan Liu, Euphy Y. Wu, Shengyu Li, Revathy Venukuttan, Ruhi Rai, W. Mu, Nahid Iglesias, P. Giusti-Rodríguez, Timothy E. Reddy, Yun Li, Raluca Gordân, Andrew S. Allen, Michael I. Love, Patrick F. Sullivan, Gregory E. Crawford, Charles A. Gersbach 2026-02-03 bioRxiv 0 27
visibility_off Sex Chromosome Turnover and Structural Genome Divergence Shapes Meiotic Outcomes in Hybridising Cobitis. S. A. Schlebusch, V. Trifonov, Z. Halenková, M. Klianitskaya, D. Dedukh, A. Ruiz-Herrera, L. Álvarez-González, Gala Pujol, E. Hřibová, L. Andjel, O. Bartoš, P. Pajer, T. Tichopád, D. Kulik, J. Kotusz, M. Kaštánková Doležálková, A. Böhne, A. Marta, Patrik Horna, R. Reifová, Y. Guiguen, Heiner Kuhl, J. Pačes, K. Janko 2026-03-24 GigaScience 0 34
visibility_off USP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 Deubiquitination Jia Cheng, Fang Fang, Zhiheng Li, Jianwei Wang, Linbo Cai, Ling Xu, Yan Tao, Juanjuan Yu, Gen Li, Zimu Zhang, Zexi Cui, Yang Yang, Tiandan Li, Di Wu, Xiaolu Li, Yifang Ding, Zong Zhai, Mengmeng Gu, X. Li, Xingxing Wu, Pengju Yang, Chunxia Shi, Huike Bai, Xiaodong Wang, Lanlan Han, Lei Shi, Jianqing Li, Jia Pan 2026-02-11 International Journal of Biological Sciences 0 19
visibility_off Changes in telomere length and mitochondrial DNA copy number in the colorectal adenoma-carcinoma sequence. Anna Valíčková, K. Tomášová, K. Balounová, Josef Horák, Michal Kroupa, Petr Hanák, Natálie Danešová, J. Jungwirth, Jan Kral, T. Hucl, Pavel Kohout, S. Summerova, M. Schneiderová, L. Vodičková, P. Vodička, Veronika Vymetálková, Soňa Vodenková 2026-02-13 Mutagenesis 0 48
visibility_off Pan-cancer evolution signatures link clonal expansion to dynamic changes in the tumor immune microenvironment. Xinyu Yang, Wei Liu, G. Macintyre, P. van Loo, Florian Markowetz, Peter Bailey, Ke Yuan 2026-03-01 Cell reports 0 71
visibility_off Nonhomologous end joining-the importance of end tethering and beyond. S. Zha, Geunil Yi 2026-03-23 Genes & development 0 43
visibility_off Abstract IA010: Spatiotemporal determinants of KRAS effector signalling in PDAC: From subclonal evolution to stromal–immune niches Dieter Saur 2026-03-05 Cancer Research 0 4
visibility_off Integrating germline and tumor sequencing to improve hereditary cancer diagnosis and care. Richarda M. de Voer, Laura Valle 2026-02-23 European journal of human genetics : EJHG 0 25
visibility_off Interclonal cooperation and suppression shape early Ras-driven tumour growth José Teles-Reis, Caroline Dillard, M. Antunes, Ashish Jain, Paula Ruiz-Duran, Minghua Deng, Dan Liu, C. Gaudin, S. Nakken, Amrinder Singh, Michael E Baumgartner, Anna M. Dahlström, V. Reinertsen, T. Rusten 2026-02-20 bioRxiv 0 38
visibility_off Co-evolution of Oncogenic KRAS Signaling and LILRBhigh Macrophages Drives Pancreatic Cancer Recurrence Jianzhen Lin, Zhenzhen Xun, Fangze Qian, Zhigao Chen, Weikang Hu, Wei Liu, Yang Wu, Hao Yuan, L. Yin, Yazhou Wang, Xiao Huang, Yujia Dang, Bin Xiao, Junli Wu, Wen-tao Gao, Jishu Wei, Qiang Li, Min Tu, Jing Zhou, Xu Feng, Zipeng Lu, Li Wen, K. Jiang, Han Liang 2026-03-07 bioRxiv 0 29
visibility_off Disrupted STIL-BRCA1 axis causes centrosome amplification and genomic instability. Srishti Sanghi, Mahima Joshi, Priyanka Singh 2026-02-26 FEBS letters 0 3
visibility_off Abstract PS2-12-19: Single cell mutational fingerprints and the viral culprits: uncovering APOBEC3 dysregulation in breast cancer J. Lehle, M. Soleimanpour, N. Haghjoo, D. Ebrahimi 2026-02-17 Clinical Cancer Research 0 2
visibility_off Spi-1 proto-oncogene regulates mRNA hypertranscription and malignant progression in head and neck cancer. Zheran Liu, Z. Qin, Huilin Li, Lili Zhu, Ling He, Na Chen, Dandan Zhu, Qinghong Liu, Lei Dai, Xingchen Peng 2026-03-18 Signal transduction and targeted therapy 0 17
visibility_off Mutant KRAS Heterogeneity Shapes Nuclear Architecture During Pancreatic Cancer Initiation Gareth Pollin, Angela J. Mathison, Elise N. Leverence, T. D. De Assuncao, J. Iovanna, Johnny C. Hong, Michael T. Zimmermann, Raul Urrutia, G. Lomberk 2026-03-01 Epigenomes 0 18
visibility_off Therapy-induced rapid drug resistance driven by genome chaos and polyploid giant cancer cells. S. Horne, J. Ye, Guo Liu, Batoul Y. Abdallah, J. Stevens, Henry H Heng 2026-02-01 Cancer letters 0 26
visibility_off Regions of genome plasticity are systematically organized into recurrent integration spots that shape accessory-genome functional architecture: insights from a complete genome of strain F1C1 and pangenomic analysis of the Ralstonia solanacearum species complex Upalabdha Dey, Jyotishpal Deka, Prerona Sharma, Mohit Yadav, Siddhartha Shankar Satapathy, S. K. Ray, Aditya Kumar 2026-02-26 bioRxiv 0 16
visibility_off Epigenetic Silencing of Primary Cilia Genes by PRAME and ETS2 in Melanoma Cells Hyeon Ho Heo, H. Youn, Eun-Yi Moon, Soo-Jong Um 2026-02-01 Journal of Cellular Physiology 0 3
visibility_off CADGE 2.0, Transcription-Translation-Coupled DNA Replication is Improved in a Chemically Modified Cell-Free System Riku Nagai, Carlos Ramirez, Z. Abil 2026-03-01 bioRxiv 0 12
visibility_off Pan-cancer analysis identifies JMJD6 as an oncogene and prognostic biomarker. Lihua Liu, Tao Li, Jing He, Guiling Liu 2026-03-18 Discover oncology 0 2
visibility_off Effect of loss of KDM6A-mediated genomic instability and metabolic reprogramming on response to therapeutic perturbations in bladder cancer. S. Goswami, Pratishtha Singh, Ranit D. Rozario, Bidisha Chakraborty, Swadhin Meher, D. Raychaudhuri, Aminah J. Tannir, Yang Li, Anurag Majumdar, Jessalyn Hawkins, Yun Xiong, Philip L. Lorenzi, Padmanee Sharma, K. Akdemir, P. Pilié, Byron H. Lee 2026-03-01 Journal of Clinical Oncology 0 21
visibility_off Abstract B036: Integrative Genomic Profiling Reveals Epigenomic, Structural, and Spatial Complexity in Meningioma Zac Carver, Roy Khalife, Jared Rice, Abha Banerjee, Shivani B. Shah, Jon-Matthew Belton, Chris Roberts, José J. Otero, Anthony M. Magliocco 2026-03-23 Cancer Research 0 5
visibility_off Abstract B021: CRISPRi screening reveals an enhancer-PLXNA1 axis as a critical regulator in ccRCC Tao Wang, Xiaosai Yao, Jeremy M. Simon, Tyler S. Klan, C. A. Gersbach, Qing Zhang 2026-03-13 Cancer Research 0 19
visibility_off Abstract : Differential Network Analysis Reveals Pathways Associated with APOBEC3 Mutational Signature in Breast Cancer Mohadeseh Soleimanpour, Diako Ebrahimi 2026-02-17 Clinical Cancer Research 0 5
visibility_off Investigating the oncogenic role of aberrant EZH2 in hepatoblastoma Kathryn Glaser, E. DePasquale, L. Berklite, Brian T. Hickner, Priyanka Rao, R. Patel, Andrew A. Badachhape, Somak Roy, Emily J Schepers, N. Timchenko, James I. Geller, S. Ranganathan, Gregory M. Tiao, Bruce J. Aronow, Takanori Takebe, Sarah E. Woodfield, Sanjeev A. Vasudevan, Alexander J. Bondoc 2026-02-06 Scientific Reports 0 40
visibility_off Single-Cell Multi-Tissue T Cell Clonal Dynamics Reveal Distinct Immune Coercion Landscapes in MSI and MSS Colorectal Cancer Qianhe Zhan, Siwen Zhang, Bofu Cao, Lanming Chen, Lu Xie 2026-03-01 International Journal of Molecular Sciences 0 6
visibility_off Intrahepatic reporter assay reveals leaky somatic blockade of L1 retrotransposition in mice May Raya, Réka Karkas, Olivia Orsolya Verebi, Ede Migh, Gergely Imre, Kitti Vecsernyés-Nagy, Katinka Szalmási, Anna Georgina Kopasz, Dominik Sándor Kocsis, P. Kálmán, Zoltán Lipinszki, Farkas Sükösd, Wenfeng An, J. Boeke, István Nagy, Peter Horvath, Andrea Mátés-Nagy, Lajos Mátés 2026-02-12 bioRxiv 0 113
visibility_off Comprehensive Cytogenetic and Genomic Profiling of the Murine AML12 (Alpha Mouse Liver 12) Hepatocyte Cell Line. Darine Y. Asar, Stefanie Kankel, Diandra T. Keller, K. Hardt, Sarah K. Schröder-Lange, Eva M. Buhl, Thomas Liehr, Ralf Weiskirchen 2026-02-24 Cells 0 8
visibility_off A high-quality telomere-to-telomere LSDV genome assembly Caroline F. Wright, Noemi Polo, Sarwar Azam, G. Freimanis, Tim Downing, J. Albarnaz 2026-03-26 bioRxiv 0 16
visibility_off Interpreting cancer genetics through a two-step “evolutionary cascade hypothesis”: bridging neutral and selective perspectives A. Ottaiano, M. Santorsola, Francesco Sabbatino, Roberto Sirica, Francesco Caraglia, Anna Ceccarelli, V. Granata, Ines Simeone, S. Zappavigna, M. Berretta, Giovanni Savarese, Michele Caraglia 2026-02-13 Journal of Translational Medicine 0 49
visibility_off Nanobody‐Mediated c‐MYC Degradation Inhibits Tumor Cell Progression Yuanyuan Xue, Hao Jiang, Zhaoyun Zong, X. Tian, Zelong Miao, Ting Li, Yali Wei, Haiteng Deng 2026-03-26 MedComm 0 10
visibility_off Eukaryotic Initiation Factor 5B (eIF5B)-Driven Translational Control Impacts Oral Squamous Cell Carcinoma Pathophysiology P. Narasimha, J. Patel, Ayan Chanda, Veda Hegde, B. Fernando, H. Stephenson, Rebecca Mubaya, Aadarsh Shrestha, S. Nakoneshny, Bo Young Ahn, T. W. Matthews, S. Chandarana, Robert D. Hart, J. Dort, Martin Hyrcza, Emilija Todorovic, S. M. Jafarnejad, Pinaki Bose, N. Thakor 2026-02-02 bioRxiv 0 27
visibility_off Accessibility at a primed distal Fshb-Kcna4 super-enhancer is facilitated by Foxl2 during gonadotrope differentiation. Tal Refael, Gil Golan, Daniella Darsa, L. Pnueli, Probir Chakravarty, Karine Rizzoti, P. Melamed 2026-03-13 Endocrinology 0 24
visibility_off Detection of Somatic Point Mutations Directly from Spatial Transcriptomics Enables in vivo Spatiotemporal Lineage Tracing Zhirui Yang, Mengdie Yao, Qing Yang, Yiheng Du, Jinhong Lu, Xing Wu, Jinran Lin, Zhuoyu Qian, Song Hu, Yonghe Xia, Huan Liu, Qiji Zhou, Xiaoyu Ma, Yan Luo, Wenxuan Fan, Weike Pei, Yuhao Xia, Xiuyan Yu, Jing Luan, Qiaoan Zhang, Yue Zhang, Qin Wang, Jianyang Zeng, Yue Zhang, Wenyu Wu, Yanmei Dou 2026-02-06 bioRxiv 0 6
visibility_off Nucleic Acids on the Surface and Lumen of Tumor-Derived Small Extracellular Vesicles as Potential Cancer Biomarkers Alicja Gluszko, Daria Kania, Chang‐Sook Hong, M. Pietrowska, James F. Conway, Theresa L. Whiteside 2026-03-01 Cells 0 29
visibility_off Transposon expansion is associated with reorganization of small RNA and DNA methylation landscapes in the morphologically minimal angiosperm Wolffia brasiliensis Daniel Buendía-Ávila, Verónica Barragán-Borrero, Pablo Luna-Rodriguez, M. Akinyuwa, L. Morello, Arturo Marí‐Ordóñez 2026-03-02 bioRxiv 0 20
visibility_off Nanopore sequencing reveals hidden landscape of short L1 transductions in colorectal cancer Päivi Nummi, Aurora Taira, Janne Ravantti, T. Norri, Niko Välimäki, A. Lepistö, L. Renkonen-Sinisalo, S. Koskensalo, Toni T. Seppälä, A. Ristimäki, Kyösti Tahkola, Anne Mattila, Jan Böhm, J. Mecklin, Emma Siili, A. Pasanen, O. Heikinheimo, Ralf Bützow, A. Karhu, Lauri A. Aaltonen, Kimmo Palin, Tatiana Cajuso 2026-02-12 Communications Biology 0 92
visibility_off KDM5C and KDM5D influence DNA methylation in adult mouse liver Emily Gibbons, Kathleen Oros Klein, Shinya Inoue, Tohru Kimura, C. Greenwood, Anna K. Naumova 2026-02-12 Biology of Sex Differences 0 3
visibility_off Horizontal transfer of chromosomal DNA mediated by an integrative and conjugative element generates frequent localized recombination in Novosphingobium aromaticivorans Marco N. Allemann, Leah H. Hochanadel, Delyana P. Vasileva, Joshua K. Michener 2026-03-25 bioRxiv 0 18
visibility_off Homologous recombination deficiency and hemizygosity drive resistance in breast cancer. A. Safonov, Minna K. Lee, David N Brown, Luca Boscolo Bielo, Miika Mehine, C. Bandlamudi, Ben O'Leary, Hong Shao, Laia Vicente, D. Muldoon, Allen Zhu, S. Ros, Antonio Marra, P. Selenica, I. Bièche, B. Wubbenhorst, E. Ferraro, L. Courtois, Rania El Botty, Mehnaj S. Ahmed, E. Moiso, J. An, M. Donoghue, Marie Will, F. Pareja, E. Nizialek, Natalia Lukashchuk, E. Sofianopoulou, Yuan Liu, Xin Huang, C. Chappey, A. Staniszewska, D. Ross, D. Mandelker, Marc Ladanyi, N. Schultz, Michael F. Berger, Maurizio Scaltriti, J. Reis-Filho, Bob T. Li, K. Offit, Larry Norton, Ronglai Shen, Kara N Maxwell, F. Couch, S. Domchek, E. Marangoni, Sohrab P. Shah, M. Albertella, V. Serra, B. Weigelt, D. Solit, K. Nathanson, M. E. Robson, Nicholas C Turner, S. Chandarlapaty, P. Razavi 2026-03-04 Nature 0 135
visibility_off Large-scale mutational analysis uncovers molecular mechanisms governing dual RNA functions in transposons Edan E. Mortman, S. H. Sternberg 2026-03-12 bioRxiv 0 33
visibility_off MGMT Promoter and Enhancer Methylation in Melanoma Brain Metastases and Glioblastoma: Shared and Distinct Features. Katharina Pühringer, Benno Fehringer, Katja Zappe, W. Berger, Serge Weis, S. Spiegl-Kreinecker, M. Cichna‐Markl 2026-02-26 Cells 0 27
visibility_off Coding sequence clustering universally predicts fine- and coarse-scale chromatin compartment landscapes R. Cerbus, Kyogo Kawaguchi, I. Hiratani 2026-02-27 bioRxiv 0 25
visibility_off Abstract PS2-12-29: Helz-mediated r-loop resolution orchestrates brca2-dependent dna repair in hormone-driven breast cancers W. Li, B. Wu, B. Gao, E. Irvin:, A. Ghosh, L. Eliaz, Y. Huang, Y. Kwon, C. M. Stiefel, T. Nguyen, D. Zhao, H. J. Suarez, T. Ni, S. Alejo, O. Fitzgerald, X. Song, E. Wasmuth, S. Zheng, J. Leung, X. Xue, H. Wang, J. Ji, L. Lan, W. Zhao 2026-02-17 Clinical Cancer Research 0 28
visibility_off Functional Characterization of POLE1 Variant Fibroblasts Reveals Replication Stress and Increased Sensitivity to Genotoxic Stress Enas Khdeda, Nora Naumann-Bartsch, Nawres Khdeda, Giulia Cramer, Laura S. Hildebrand, Paula Schiller, Paul Wagner, Franziska Fahrmeier, U. Hüffmeier, Stefanie Corradini, L. Distel, Lukas Kuhlmann 2026-03-01 Diseases 0 36
visibility_off Beyond Oncogenes: Selectively Targeting Whole-Tumor Cell Growth Regulation. Albert Qin 2026-02-01 Drug design, development and therapy 0 3
visibility_off Emerging trends and converging evidence in tumor evolution: A comprehensive review. Chenqi Jin, Weiqi Li, Boqiang Liu, Lu-Qi Cao, S. Stefan, Luoxi Yuan, Xin Yu, Liang Shi, Hong Yu 2026-02-01 Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 1 17
visibility_off Stepwise evolutionary transitions in Cladophorales plastid genomes reveal origins of hairpin chromosomes. Saelin Bjornson, Trevor T Bringloe, Kavitha Uthanumallian, Ricardo De Paoli-Iseppi, Michael B. Clark, Chiela Cremen, Riyad Hossen, Owen McGinley, Tara Jalali, John A. West, Frederik Leliaert, Richard Wetherbee, O. De Clerck, Sebastián Duchêne, Jacob L. Steenwyk, Heroen Verbruggen 2026-03-01 Current biology : CB 0 47
visibility_off Functional correction and genome integrity with duplex base editing of β-thalassemic hematopoietic stem cells Nikoletta Y Papaioannou, Petros Patsali, Julia Klermund, P. Papasavva, G. Andrieux, L. Koniali, Basma Naiisseh, S. Christou, Maria Sitarou, M. Kleanthous, Toni Cathomen, C. Lederer 2026-02-02 Genome Biology 0 28
visibility_off A07 | Optical genome mapping: the new frontier of cytogenomic diagnosis? L. Zanatta 2026-03-03 Haematologica 0 12
visibility_off Quantification of the Human Satellite 2 (HSAT2) Repeat in the Plasma Cell-Free DNA of Patients with Colon Cancer E. E. Yörüker, E. Özgür, C. Kulle, Betül Aksu, Ilgin Demir, A. Bronkhorst, S. Holdenrieder, U. Gezer 2026-02-27 Current Issues in Molecular Biology 0 23
visibility_off Modeling the impact of unequal recombination on multigene family copy number variation in apomictic lineages. Abir Elguweidi, Emhimad E Abdalla, T. Crease 2026-02-26 Genome 0 37
visibility_off Baseline cellular state dictates the molecular impact of KRAS mutant variants in pancreatic cancer cells Yanixa Quiñones-Avilés, Barbora Šalovská, Cassandra S. Markham, Yi Di, Benjamin E. Turk, Yansheng Liu, M. Muzumdar 2026-03-12 bioRxiv 0 16
visibility_off TEsingle enables locus-specific transposable element expression analysis at single-cell resolution Talitha Forcier, Esther Cheng, Oliver H. Tam, Cole Wunderlich, Laura Castilla-Vallmanya, Joanne L. Jones, Annelies Quaegebeur, Roger A. Barker, J. Jakobsson, M. Hammell 2026-03-22 bioRxiv 0 11
visibility_off Defining mutational signatures of lung cancer-associated carcinogens through in vitro exposure of human airway epithelial cells Natasha Q Gurevich, D. Chiu, Masanao Yajima, Jonathan H. Huggins, Sarah A. Mazzilli, Joshua D. Campbell 2026-03-09 bioRxiv 0 15
visibility_off Unannotated noncoding transcripts as a source of intratumor heterogeneity in malignant cell states. Xiaolan Zhou, Limin Lin, Yu Chen, Guang Yang, Ting Ni, Zhaozhao Zhao 2026-03-16 Science China. Life sciences 0 8
visibility_off Mithramycin alters EWS::FLI1 DNA binding and RNA polymerase II processivity to inhibit nascent transcription Rebecca S. Kaufman, Guillermo Flores, E. Boguslawski, Seneca S Kinn-Gurzo, Maggie H. Chassé, Ian Beddows, Marie Adams, M. Stout, Lauren M. Gaetano, R. Lopez, Sridhar M Veluvolu, Andrew Fuller, Susan M Kitchen-Goosen, Zachary P Tolstyka, Jenna M Gedminas, P. Grohar 2026-02-16 Nature Communications 0 23
visibility_off Molecular basis for the inhibition of de novo DNA methylation by TCL1A. Qingting Liu, Jinhong Li, Xiaoxiao Wang, Yaozong Li, Yu Wu, Zhuo Han, Zixin Guo, Li Guo, Xiang Wang, Gang Yuan, Zheng Gao, Lei Li, Dong Deng 2026-03-05 Nature communications 1 10
visibility_off BTAF1: a key regulator of DNA end resection and predictor of chemotherapy sensitivity in gastric cancer. Juan Xie, Ji-Liang Lin, Zhi-Cheng Xiang, Chunhua Qu, Xiaoxia Cai, Run-Cong Nie, Peng Lin, Yiting Yin, Jin-Ling Duan, Dan Xie, Mu-yan Cai 2026-03-17 Cell death and differentiation 0 21
visibility_off Lineage-restricted dependency on an oncofetal SNHG29-IGF2BP1 RNA axis in acute megakaryoblastic leukemia R. Winkler, Bruno Griesler, W. Sippl, R. Boon, I. Wittig, M. Yaspo, S. Hüttelmaier, Raj Bhayadia, Dirk Heckl, J. Klusmann 2026-02-10 bioRxiv 0 64
visibility_off Abstract A025: SLC1A1/EAAT3 sustains oncogenic metabolic programs in kidney cancer Treg M. Grubb, Pooneh Koochaki, Sayed Matar, Fatme Ghandour, M. Machaalani, Eddy Saad, Cerise Tang, E. Reznik, Jesminara Khatun, Carleigh Salem, Noah Dubasik, David A. Orlando, Matthew G. Guenther, Gyanu Parajuli, Raghvendra Srivastava, Steven R. Martinez, Jesse Coker, R. Kotecha, A. Hakimi, John M. Asara, Timothy A. Chan, S. Vanharanta, Shaun R. Stauffer, W. Kaelin, Sabina Signoretti, T. Choueiri, Abhishek A. Chakraborty 2026-03-13 Cancer Research 0 28
visibility_off c-Myc transactivates CFL1 to induce senescence-like phenotype and potentiate the bystander effects for the migration and proliferation in lung cancer cells Yen-Ting Chou, J. Leu, Wan-Yu Yang, Chien‐Hsiu Li, Min-Ying Lin, C. Kao, Yu-Chan Chang, Michael Hsiao, Yi-Jang Lee 2026-03-26 Cell Death Discovery 0 27
visibility_off Crosstalk between EZH2 and DNA methylation mediates neuroendocrine prostate cancer lineage plasticity. Richa Singh, V. B. Venkadakrishnan, Eddie Imada, Yasutaka Yamada, Nicholas J. Brady, Kate E Dunmore, Richard Garner, Matthew A. Booker, B. Hanratty, Michael C. Haffner, M. Tolstorukov, L. Marchionni, Brian D. Robinson, D. Rickman, H. Beltran 2026-02-21 Nature communications 0 43
visibility_off Two paired HPV-59 cervical cancer cell lines with distinct chemoradioresistant phenotypes Irina S Tatarnikova, Vadim Talyshev, A. Sen’kova, Oleg Markov, D. Mikhailova, Oksana Pashkovskaya, S. Krasilnikov, E. Samoilova, Tatyana Gainer, Evgeniy Brener, M. Zenkova, E.B. Logashenko 2026-02-04 Scientific Reports 1 12
visibility_off Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types S. Sauty, Jacqueline Shine, Hamed Bostan, Jian-liang Li, P. Mieczkowski, Richard F. Loeser, B. Diekman, Dmitry A. Gordenin 2026-02-15 bioRxiv 0 26
visibility_off The RNA Editome of Esophageal Squamous Cell Carcinoma Identifies an ADAR1-CDK13 Editing Feedback Loop Mediating cGAS–STING Activation in Early Tumorigenesis Lihong Huang, Minglei Yang, Douyue Li, Guozhong Jiang, Wenliang Zhang 2026-01-30 bioRxiv 0 4
visibility_off Characterization of the clonal hierarchy and immunophenotype of PTPN11 mutations in acute myeloid leukemia. S. Fobare, Chi Sharpe, Kate Quinn, Kinsey Bryant, Linde A. Miles, Robert L. Bowman, C. Cheney, Casie Furby, Marissa Long, Kaytlynn Fyock, Ben Wronowski, James R. Lerma, K. Mrózek, D. Nicolet, T. Sesterhenn, Megan E. Johnstone, Jianmin Pan, Shesh N Rai, C. Pasare, Nives Zimmermann, Wen-Mei Yu, Cheng-Kui Qu, Andrew J. Carroll, R. Stone, Eunice S. Wang, J. Kolitz, Bayard Powell, J. Perentesis, Ann-Kathrin Eisfeld, E. Hertlein, John C. Byrd 2026-02-23 JCI insight 0 80
visibility_off CO54 | Biallelic loss of RB1 and LPAR6 at 13q14 drives key cell cycle abnormalities in T-cell acute lymphoblastic leukemia F. Servoli 2026-03-03 Haematologica 0 4
visibility_off The segregation of organelles and organellar genomes across eukaryotic biology. Clirim Jetishi, M. Gerber, T. Ochsenreiter 2026-03-01 Biochemical Society transactions 0 26
visibility_off Expansion of preexisting cancer driver mutant clones is induced by the genotoxic carcinogen benzo[b]fluoranthene in MutaMouse lung Jennifer B Faske, Binsheng Gong, D. LeBlanc, J. Funk, G. Zhou, Sabrina Kehm, P. White, Timothy W. Robison, A. Zeller, Carole L. Yauk, F. Marchetti, Barbara L Parsons 2026-03-01 Toxicological Sciences 0 14
visibility_off Circular permutation engineering improves amplification efficiency of Bst DNA polymerase. Rong Xiang, Guangyi Liu, Yanru Wang, Yi Hou, Song-Qing Hu 2026-02-01 International journal of biological macromolecules 0 4
visibility_off Abstract PR015: Epigenetic Dysfunction Promotes Dependence on the NF-I/A Transcription Factor in Kidney Cancer Carleigh Salem, Jason M. Scovell, Shannon Zayas, Cerise Tang, A. Dighe, Treg M. Grubb, Neil Ruthen, S. Nur, Belinda B Willard, S. Vanharanta, F. Kuo, A. Hakimi, David A. Braun, E. Reznik, Abhishek A. Chakraborty 2026-03-13 Cancer Research 0 31
visibility_off Single Cell RNA Transcriptomics of Mantle Cell Lymphoma Reveals the Presence of Treatment-Resistant Subclones at the Time of Diagnosis. Dmitry Manakov, M. Klanova, M. Kolář, R. Ivanek, Florian Geier, Julien Roux, Tomas Zikmund, L. Winkowska, E. Kriegova, J. Manakova, L. Tušková, Silvia Spanikova, Alexandra Scasna, M. Trněný, Pavel Klener 2026-03-09 American journal of hematology 0 33
visibility_off Assessment of Homologous Recombination System Gene Expression in Chemologically Induced Carcinogenesis In Vivo Models M. M. Tsyganov, Danna Zh. Bulatova, A. A. Fedorenko, Dmitry M. Loos, P. E. Nikiforov, I. A. Tsydenova, A. A. Bayanbayeva, Zh. Sharipkhanova, S. Timoshenko, M. Ibragimova 2026-03-01 Current Issues in Molecular Biology 0 16
visibility_off Genomic profiling of meiotic errors and early malignant transformation events in ovarian mature teratoma. Kotaro Takahashi, Ryo Tamura, K. Suda, N. Yachida, M. Yamaguchi, Roselit Mathew, Shujiro Okuda, Kosuke Yoshihara, Hirofumi Nakaoka 2026-03-15 Reproduction 0 15
visibility_off The protein phosphatase 2A-B56α complex regulates N-Myc degradation in neuroblastoma Brian Tran, I. Peris, Ethan Wurman, Averie Huang, G. H. Onishi, Jiang Hu, Rita A Avelar, Erika A. Newman, A. Difeo, Caitlin M. O’Connor, G. Narla 2026-02-01 The Journal of Biological Chemistry 0 51
visibility_off A06 | TP53 in myeloid neoplasms M. Voso 2026-03-03 Haematologica 0 56
visibility_off UHRF1-DNMT1 Cooperation in Cytosine Base Flipping and Maintenance Methylation: Mechanistic and Oncogenic Insights from HeLa Cells Chilanay M. Alakbarova 2026-01-30 Journal of Molecular Biosciences and Engineering 0 0
visibility_off Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans Marilina Raices, F. Balmir, Nicola Silva, Wei Li, McKenzie K. Grundy, Dane Hoffman, Elisabeth Altendorfer, C. Camacho, Kara A. Bernstein, M. Colaiácovo, J. Yanowitz 2026-03-25 eLife 0 41
visibility_off Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-associated DNA damage Alexandra Nusawardhana, Anastasia Hale, Joshua Straka, Claudia M. Nicolae, George‐Lucian Moldovan 2026-02-24 Nucleic Acids Research 0 32
visibility_off Massive proliferation of retrotransposons contributes to genome size expansion in species of the Pseudocercospora genus. Sandra-Milena González Sáyer, Ibonne A Garcia, Cristian A Traslaviña, Alex Z. Zaccaron, I. Stergiopoulos, F. A. Aristizabal, Ursula Oggenfuss, D. Croll 2026-02-26 Mobile DNA 0 54
visibility_off MORC2 promotes acute myeloid leukemia by silencing LINE-1 retrotransposon Shuai Wang, Fu-Bo Wang, Zixuan Li, Nana Wang, Zhidong Gu, Zhimin Gu 2026-02-21 Functional & Integrative Genomics 0 4
visibility_off Advances in Double‐Stranded DNA Targeting Technologies Zuhao Shen, Yiqun Liu, Yinghong Hao, Yifan Bo, Xiaochuan Dai, Shihui Wang, T. Xia, Xin Su, Huiyu Liu 2026-02-01 Exploration 0 42
visibility_off COPG1 Is a Selectively Essential Regulator of Cancer Progression and Chemoresistance via Redox Modulation and AKT Signaling. S. Sen, Vandon Duong, Y. Hwang, Seungmin Kim, Euijin Lee, Myoung-Eun Han, Dongjun Lee, Sik Yoon, Sae-Ock Oh 2026-02-10 International journal of molecular sciences 0 24
visibility_off Tissue-specific DNA Repair Strategies Underlie Apparent High Transposon Activity in the C. elegans Soma. Cindy Chang, David D. Lowe, Scott G. Kennedy 2026-03-18 G3 0 4
visibility_off The oncogenic role of ecotropic viral integration site 1 in hematological malignancies: mechanisms of activation and leukemogenesis. Yuchao Hao, Jing Liu, Jiacheng Lou, Jinsong Yan 2026-02-16 Frontiers in immunology 0 5
visibility_off A genome-wide CRISPR-Cas9 screen identifies TGN46 as a host determinant for H-1PV susceptibility in pancreatic adenocarcinoma G. Labrousse, Nina Suarez, Adèle Nevot, Naïma Hanoun, N. Dusetti, Louis Buscail, C. Murgia, Pierre Cordelier 2026-03-11 bioRxiv 0 18
visibility_off The CRL4Cdt2 E3 ubiquitin ligase: A comprehensive review of its substrates, mechanisms, and roles in genomic stability Afiqah Aimie Murba, M. Ibrahim, Sarah Shazwani Zakaria, N. H. Adenan, M. Jamaludin, H. Nishitani, Mohd Shukuri Mohamad Ali, Muadz Ahmad Mazian 2026-03-06 Asia-Pacific Journal of Molecular Biology and Biotechnology 0 34
visibility_off Objective method to estimate the duration of the DNA replication cycle without perturbation in Escherichia coli Alix Meunier, F. Sarron, Isabelle Bru, Meriem Benkhelifa, Erick Denamur, Manuel Campos 2026-02-11 bioRxiv 0 9
visibility_off Abstract PS3-06-12: Pre-existing TOP2A-High Cells Drive Resistance to Trastuzumab Deruxtecan in HER2+ Breast Cancer S. Han, M. Jung, J. Lee, S. Rhie 2026-02-17 Clinical Cancer Research 0 4
visibility_off Abstract B017: From healthy brain to cancer cells: Understanding the origins of glioblastoma through the lens of Darwinian evolution J. SALAZAR SALAZAR, Sean W. McHugh, Maria F. Gonzalez-Aponte, Hugo Guerrero-Cázares 2026-03-23 Cancer Research 0 5
visibility_off Abstract B047: EIF4A Blockade Drives Neoantigen Generation and Immune Remodeling in Pancreatic Cancer Kamini Singh 2026-02-18 Cancer Immunology Research 0 1
visibility_off The Cell Surface Proteome of Malignant Peripheral Nerve Sheath Tumors Reveals Therapeutic Targets Christopher M. Stehn, Liangjun Wang, Zachary J. Seeman, David A. Largaespada 2026-03-14 bioRxiv 0 3
visibility_off Profiling cell proliferation after whole-genome duplication in human cells Guang Yang, Masaya Inoko, Kaito Ogura, Sumire Ishida-Ishihara, Yuki Tsukada, Akira Funahashi, Masanao Sato, Ryota Uehara 2026-03-13 bioRxiv 0 5
visibility_off Abstract A032: Efficacy of nuclear envelope protein targeting CAR T cell therapy for MYC driven group 3 medulloblastoma Yujin Suk, Jorge Ibañez-Vega, Martin A. Rossotti, V. Shaikh, Yiyun Chen, Hardikkumar Patel, Laura Escudero, A. Delaidelli, S. Slassi, C. B. Bazan, Aapti Khanna, Sumayyah Sokeechand, Erika Apel, Iqra Chaudhry, S. Custers, Shan Grewal, Mohamed Taleb, Takuma Nakashima, W. Maich, Lucas Asselstine, D. McKenna, M. Subapanditha, P. Miletic, Yuxi Xiao, W. Gwynne, Jason Moffat, Hiromichi Suzuki, Poul H Sorensen, Ray Truant, Kevin A. Henry, E. Sotillo, C. Venugopal, Crystal L. Mackall, G. Krenciute, Sheila K. Singh 2026-03-23 Cancer Research 0 30
visibility_off tRF-1432 orchestrates RBMS1-IMPDH2 regulatory control to drive purine-dependent chemoresistance in breast cancer. Y. Dai, Xiaowei Wu, Xin Cheng, Jingqi Shang, Ziyi Yu, Yiqin Xia, S. Pei, Ya-Ting Kang, Jian Jin, Shui Wang, Hui Xie, Yangyang Cui 2026-03-01 Cancer letters 0 13
visibility_off Abstract A043: Single-cell and bulk transcriptomics uncovers GATA3-mediated macrophage immunosuppressive programming in murine and human cancers Harry Xiao, T. Dar, Satchel Stevens, J. Viramontes, S. Shiao 2026-02-18 Cancer Immunology Research 0 4
visibility_off Sustained MYC Overexpression Drives Myeloid Differentiation Block and Acquisition of Leukemic Phenotypes. N. Stokes, Saul Carcamo, D. Demircioglu, Xuedi Wang, Malgorzata Olszewska, D. Hasson, Hideo Watanabe, E. Papapetrou, David Dominguez-Sola 2026-03-01 Experimental hematology 0 32
visibility_off Genetic and genomic approaches to explore roles for the conserved 3'-5' exoribonuclease EXOSC10 in normal and malignant cells. Radhika Sain, Julian Primig, Michael Primig 2026-02-25 RNA 0 2
visibility_off SMC4/SMAD3/NF-κB axis drives cervical cancer progression and radioresistance via DNA damage repair and immune modulation. Haixia Wu, Yilin Yu, Wei Wang, Qin Xu 2026-03-09 Journal of translational medicine 0 4
visibility_off Bridging cancer cell-intrinsic driver genes and -extrinsic cell-cell communication with Driver2Comm. Runzhi Xie, Junping Li, Yuxuan Hu, Lin Gao 2026-02-17 PLoS computational biology 0 10
visibility_off A chromosome-level genome assembly of Platycladus orientalis and comparative genomics reveal pivotal roles of transposable elements in gene duplication and pseudogenization across gymnosperm giga-genomes. Yu-Tao Bao, Ren-Gang Zhang, Hui Liu, Zhi-Chao Li, Si-Qian Jiao, Kaihua Jia, Shanshan Zhou, Shuai Nie, Xue-Mei Yan, Tian-Le Shi, Xue-Chan Tian, Shilei Zhao, Lei Kong, Zhaojin Chen, Hai-Yao Ma, Xiao-Lei Yang, Charles Chen, Y. El-Kassaby, I. Porth, Xiao-Ru Wang, Jian-Feng Mao, Wei Zhao 2026-03-01 Plant communications 0 39
visibility_off The function of DNA methylation in lung cancer: Diagnostic and clinical implications Dr. Deepthi Yadav, Santosh Kumar, Shiwa Chaubey, Mohan Tiwari, Patrick Michael Chipoya 2026-03-11 Innovative Medicines & Omics 0 3
visibility_off Abstract B034: Genetic and non-genetic mechanisms of resistance to KRAS inhibition in CRC S. Alonso, Kevan Chu, Marie J Parsons, Elizabeth Granowsky, J. Shia, R. Yaeger, Lukas E. Dow 2026-03-05 Cancer Research 0 97
visibility_off In vivo lineage tracing across human tissues using methylation barcodes in the protocadherin gene cluster Samuel F. Hackett, C. Boniface, Adriana V.A. Fonseca, Akemi D. Ramos-Yamasaki, Caroline J. Watson, H. Bazin, Amanda Tan, H. L. Yu, Lars L P Hanssen, H. Dev, S. Apostolidou, A. Gentry-Maharaj, Sadik C Esener, U. Menon, Jamie R. Blundell 2026-02-23 bioRxiv 0 61
visibility_off Abstract B032: Drug and single-cell gene expression integration identifies heterogeneity-aware synergistic combinations for glioblastoma Robert K. Suter, Anna M. Jermakowicz, Rithvik Veeramachaneni, Matthew D’Antuono, Longwei Zhang, R. Chowdary, Simon Kaeppeli, Madison Sharp, Pravallika Palwai, Vasileios Stathias, Grace Baker, Luz Ruiz, Winston Walters, Maria Cepero, Danielle M. Burgenske, Edward B Reilly, Anatol Oleksijew, Mark G. Anderson, S. Williams, Michael E. Ivan, Ricardo J Komotar, Macarena I. de la Fuente, Gregory Stein, Alexandre Wojcinski, Santosh Kesari, J. Sarkaria, Stephan C. Schürer, Nagi G. Ayad 2026-03-23 Cancer Research 0 77
visibility_off The role of cohesin and DNA loop extrusion in the generation of single neuron identity. Lea Kiefer, Tom Maniatis, Daniele Canzio 2026-02-17 Current opinion in genetics & development 0 14
visibility_off A programmable platform enabling targeted chromosome substitution and cross-species stability profiling. Lei Shi, Xiali Yang, Mingdi Wu, Chen Zhao, Jun Wu, Erwei Zuo 2026-03-09 Protein & cell 0 23
visibility_off Single-cell genomics highlight MYC-associated metabolic activation and altered cell interactions in T-prolymphocytic leukemia progression Linus Wahnschaffe, Dennis Jungherz, T. A. Müller, T. Pemovska, A. Pichler, Stéphanie Poulain, Edith Julia, S. Timonen, Martin Böttcher, Qu Jiang, D. Beverungen, Julia Bischoff, Marek Franitza, T. Georgomanolis, Kerstin Becker, Michael Hallek, D. Mougiakakos, T. Zenz, S. Mustjoki, Emmannuel Bachy, C. Herbaux, A. Schrader, N. Pflug, Philipp B. Staber, T. Braun, Marco Herling 2026-03-09 Nature Communications 0 59
visibility_off Tracing the molecular route to progression in miRNA-biogenesis-defective thyroid lesions Anne-Sophie Chong, Carla Roca, Paula Morales-Sánchez, E. Dorca, Verónica Barea, Ignacio Ruz-Caracuel, Pablo Valderrabano, Carlota Rovira, Cristina Jou, Dorothée Bouron-Dal Soglio, R. Chernock, G. Torrezan, M. Pusztaszeri, J. Cameselle-Teijeiro, Xavier Matias-Guiu, Clara V. Alvarez, H. Salvador, Jonathan D Wasserman, L. Leandro-García, William Foulkes, Eduardo Andrés-León, Paula Casano-Sancho, Barbara Rivera 2026-02-09 JCI Insight 0 40
visibility_off Molecular background of Philadelphia chromosome dependent enhancement of cellular growth and tyrosine kinase inhibitor sensitivity Md. Faruq Hossain, L. Hagenau, Lars R. Jensen, J. Rhode, Thomas Sura, M. G. Salazar, A. Tzvetkova, Corinna Jensen, S. Edwards, H. Dunkel, Stefan Simm, J. Radke, A. W. Kuss 2026-02-19 Experimental Hematology & Oncology 0 13
visibility_off Abstract B015: Chromothripsis driven loss of NSD1 and SETD2 disrupts an epigenetic-kinase circuit governing mitotic fidelity R. Dere, Ashley Boice, Richard Han, Xiaoli Wang, M. Motrapu, Pratim Chowdhury, Sung Jung, B. V. Prasad 2026-03-13 Cancer Research 0 20
visibility_off Development of an error-corrected next-generation sequencing method for the quantification of hotspot cancer driver mutations Kelly L Harris 2026-02-14 Cell Signaling 0 1
visibility_off A new cancer progression model: from synthetic tumors to real data and back Daniela Volpatto, S. G. Contaldo, Simone Pernice, Marco Beccuti, F. Cordero, R. Sirovich 2026-02-09 bioRxiv 0 3
visibility_off ARID1A Mediates SWI/SNF-Independent Maintenance of Heterochromatin Architecture to Restrain Viral Mimicry and Immunogenicity in Colon Cancer. Qian Li, Zhe Zhang, Yihao Wang, Xiangdong Peng, Yan Fang, Yujun Zhang, Ling-Xiao Chen, Ting Huang, Zhengduo Yang, Chunliang Li, Lingjie Li, G. Mills, Xuetong Shen, Hongyan Wang, Jianfeng Shen 2026-02-09 Cancer research 0 33
visibility_off Cell-Free DNA as Biomarker in Oral Squamous Cell Carcinoma: Dynamics, Mutational Landscape and Clinical Implications Pedro Veiga, Leonor Barroso, L. Pires, Carolina Mano, F. Caramelo, I. Carreira, I. Ribeiro, J. B. de Melo 2026-03-01 Cells 0 9
visibility_off Endless forms - how genome organization underlies evolution and development. A. Edwards, Elizabeth H. Finn 2026-02-06 Journal of cell science 0 11
visibility_off Paclitaxel-induced germline DNA-damage signatures independent of mismatch repair in C. elegans Yebin Hong, Zifei Liu, Hyun-Min Kim 2026-02-18 Frontiers in Pharmacology 0 3
visibility_off Why DNA Is the Key Control of Life? A. Sato 2026-03-26 Science Insights 0 9
visibility_off Single-Cell Analysis Identified a Recurrent Malignant-Associated Transcriptional State in Colorectal Cancer. Sadahiro Iwabuchi, K. Sawada, M. Kojima, Miho Ozawa, H. Taniguchi, H. Bando, Kazumi Abe, Yuta Kuze, Kiyomi Imamura, Y. Kashima, Y. Hirohashi, Atsushi Tajima, T. Torigoe, Yutaka Suzuki, T. Yoshino, Shinichi Hashimoto 2026-03-02 Cancer science 0 59
visibility_off MosaicLev: Modified Levenshtein distance for mobile element-aware genome comparison Harry Stoltz, Thomas E. Kuhlman 2026-02-05 bioRxiv 0 3
visibility_off The landscape of B and plasma cells in breast cancer: insights from single-cell and spatial transcriptomics. Xing Cai, Jinru Yang, Wenzheng Wang, Xiaolu Zhan, Xiaohan Chen, Dongchen Ji, Kexin Liu, Xue Li, Yuxing Zhang, Cheng Qian, Xiaofang Dai, Guang Yang, Tong Liu 2026-03-12 NPJ breast cancer 0 6
visibility_off Gene duplication is associated with gene diversification and potential neofunctionalization in lung cancer evolution P. Ashford, A. Frankell, Zofia Piszka, Camilla S. M. Pang, M. Abbasian, Maise Al Bakir, M. Jamal-Hanjani, N. Mcgranahan, C. Swanton, Christine A. Orengo 2026-02-19 Genome Research 0 75
visibility_off The Mechanisms of Tumor Susceptibility Associated with BRCA1/BRCA2 Genetic Mutations Zhenan Shi 2026-02-02 Theoretical and Natural Science 0 1
visibility_off Assessing positive selection in centromere-associated kinetochore proteins across Metazoan groups H. Healey, L. E. Gomez, S. I. Sheikh, Benjamin R. Camel, Andrew A. Forbes, K. Sterner, Emily A. Beck, Sunnyside Ave 2026-02-16 bioRxiv 0 19
visibility_off cfGWAS reveal genetic basis of cell-free DNA end motifs Huanhuan Zhu, Yan Zhang, Linxuan Li, Shuang Zeng, Xinyi Zhang, Ying Lin, Rijing Ou, Lin Wang, Xiameizi Li, Yu Wang, J. Zeng, Yu Lin, Chuangze Xu, Guodan Zeng, Lingguo Li, Rong Zhao, Yongjian Jia, F. Luo, Meng Yang, Yuxuan Hu, Han Xiao, Xun Xu, Jian Wang, Aifen Zhou, Haiqiang Zhang, Xin Jin 2026-02-14 Nature Communications 0 20
visibility_off Integrated analysis of extrachromosomal circular DNA and transcriptome reveals associations between microbial profiles and Immunoinflammatory markers in hypospadias Zhilin Yang, Jiaying Yu, Xiaoning Hong, Jianchun Yin, Tiejun Zhang, Changze Song, Chunxiao He, Shuang Mao, Huisheng Yuan, Peng Han, Jiang Li, Xi Xiang, Shoulin Li, Zilong Wang 2026-02-16 World Journal of Urology 0 7
visibility_off Single-nucleus ATAC-seq analysis resolves chromatin and transcriptional features of fibrolamellar carcinoma. Alaa R. Farghli, Marc S. Sherman, Bo Shui, Andreas Stephanou, Brian J Pepe-Mooney, Colton J. Smith, Donald Long, Paul R. Munn, Adrian J. McNairn, Jennifer K. Grenier, Michael Karski, Wolfram Goessling, Khashayar Vakili, Praveen Sethupathy 2026-03-21 Scientific reports 0 17
visibility_off Integrating bulk and single cell RNA sequencing to predict the potential therapeutic efficacy of DLX5 in hypopharyngeal squamous cell carcinoma. Yao Jiang, Lianhe Li, Hongmin Wang, Mingqiong Wang, Liangyu Zou 2026-03-03 European journal of medical research 0 2
visibility_off Chemoradiation Reprograms Tumor Cells and the Immune Microenvironment in Cervical Cancer. T. Sandoval, Yize Li, Naoshad Muhammad, Tresha Desai, R. Jayasinghe, Saman Zeeshan, K. Jayachandran, M. Inkman, Michael Waters, Eliwaza Naomi S Msengi, Tyler R. McKinnish, Ibrahim Hatipoglu, Ana Carolina Paschoalini Mafra, Muyassar Anwar, Donghua Hu, Dhaval P. Bhatt, Varintra E Lander, R. J. Mashl, Andrew Houston, Liyun Chen, Jessika Contreras, Clifford G Robinson, Sherri R. Davies, Julie Belmar, Shunqiang Li, M. Major, David G DeNardo, Stephanie Markovina, Brian T Edelson, Jin Zhang, Li Ding, Julie K. Schwarz 2026-03-20 Cancer research 0 28
visibility_off Leukemia stem cell expansion cultures reveal clonal drivers of leukemogenesis and therapy response Indranil Singh, Andrea Polazzi, Alex Maya Pombo, Marta López-Osias, C. Bauer, Maria Guarini, P. Sánchez, Luna Goulet, Carmen Gallardo, Daniel Fernández-Pérez, Robert L. Bowman, Alejo E. Rodriguez-Fraticelli 2026-02-25 bioRxiv 0 21
visibility_off Discovery of a small peptide that activates both APCCdc20 and APCCdh1 in yeast, driving increased lifespan R. E. Harris, S.D. Postnikoff, N. Shukla, A.H. Harkness, C. Z. Verdugo, B.M. Waddell, C. Wu, T.A.A. Harkness 2026-02-18 bioRxiv 0 4
visibility_off P036 | Germline and somatic cohesin genes alterations in pediatric acute lymphoblastic leukemia Domenico Gaspari 2026-03-03 Haematologica 0 0
visibility_off The role of retrotransposons in hematopoiesis and cancer. Julia Phan, Feyza Cansiz, A. Westendorf, Jan Buer, A. Tasdogan 2026-03-01 Trends in cell biology 0 4
visibility_off Genomic landscape and homologous recombination deficiency in malignant germ cell tumors reveals sex-specific therapeutic opportunities. Boheng Xu, Jiahong Chen, Huiting Peng, X. Su, Caiyun He 2026-03-14 The Journal of pathology 0 17
visibility_off Cancer-associated KBTBD4 mutations induce differentiation defects and confer a unique therapeutic vulnerability Rohit Sivaprasad, Kristijonas Žemaitis, David Linfeldt, Sudip Ghosh, Anne de Snaijer, Mattias Magnusson, F. Ek, Jenny Hansson, Agatheeswaran Subramaniam 2026-03-14 bioRxiv 0 16
visibility_off A base editing resource for functional annotation of DNA repair variants in breast-derived cell models Wardah Masud, Ludovica Russo, Vincent Chapdelaine-Trépanier, Samuel B. Hayward, Wei He, M. Ciró, C. Mercurio, Han Xu, Alberto Ciccia, Raquel Cuella-Martin, G. Leuzzi 2026-03-26 Frontiers in Cell and Developmental Biology 0 33
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