ecDNA forecasting

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Manually curated articles on ecDNA forecasting

Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations
visibility_off Extrachromosomal DNA in Cancer. V. Bafna, P. Mischel 2022-05-24 Annual review of genomics and human genetics 36 103 open_in_new
visibility_off Extrachromosomal DNA: An Emerging Hallmark in Human Cancer. Sihan Wu, V. Bafna, Howard Y. Chang, P. Mischel 2021-11-09 Annual review of pathology 73 138 open_in_new
visibility_off EcDNA hubs drive cooperative intermolecular oncogene expression King L. Hung, K. Yost, Liangqi Xie, Quanming Shi, K. Helmsauer, J. Luebeck, R. Schöpflin, Joshua T. Lange, R. Chamorro González, Natasha E Weiser, Celine Y. Chen, Maria E. Valieva, I. Wong, Sihan Wu, S. R. Dehkordi, Connor V. Duffy, K. Kraft, Junfang Tang, J. Belk, John C. Rose, M. Corces, Jeffrey M. Granja, Rui Li, Utkrisht Rajkumar, Jordan Friedlein, A. Bagchi, Ansuman T. Satpathy, R. Tjian, S. Mundlos, V. Bafna, A. Henssen, P. Mischel, Zhe J. Liu, Howard Y. Chang 2020-11-20 bioRxiv 114 145 open_in_new
visibility_off Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers Hoon Kim, Nam Nguyen, Kristen M. Turner, Sihan Wu, A. Gujar, J. Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi, S. Amin, E. Yi, F. Menghi, J. Schulte, A. Henssen, Howard Y. Chang, C. Beck, P. Mischel, V. Bafna, R. Verhaak 2020-07-19 Nature genetics 341 138 open_in_new
visibility_off Chromothripsis drives the evolution of gene amplification in cancer Ofer Shoshani, Simon F. Brunner, R. Yaeger, P. Ly, Yael Nechemia-Arbely, D. H. Kim, Rongxin Fang, Guillaume A. Castillon, Miao Yu, Julia S Z Li, Ying Sun, Mark Ellisman, B. Ren, P. Campbell, D. Cleveland 2020-12-23 Nature 299 159 open_in_new
Abstract Title Authors Publication Date Journal/ Conference Citation count Highest h-index View recommendations

Abstract Title Authors Publication Date Journal/Conference Citation count Highest h-index
visibility_off Extrachromosomal circular DNA drives dynamic genome plasticity: emerging roles in disease progression and clinical potential Bin Shi, Ping Yang, Huaijin Qiao, Daojiang Yu, Shuyu Zhang 2025-05-25 Theranostics 0 4
visibility_off Accurate Prediction of ecDNA in Interphase Cancer Cells using Deep Neural Networks Utkrisht Rajkumar, Gino Prasad, Ellis J Curtis, I. Wong, Xiaowei Yan, Shu Zhang, Lotte Brückner, Kristen Turner, Julie Wiese, Justin Wahl, Sihan Wu, J. Theißen, Matthias Fischer, Howard Y. Chang, A. Henssen, P. Mischel, V. Bafna 2025-06-27 bioRxiv 0 72
visibility_off Oncogenic drivers shape the tumor microenvironment in human gliomas Bo Zhao, Chae Yun Cho, Lingqun Ye, Tula Keal, Thomas Mitchell, Inés Martín-Barrio, C. A. Faraj, Mesut Unal, Jessica Alsing, Nora M Lawson, Ellie Rahm Kim, Francisco Chavez, Kristy Mendoza Rangel, Sanjay K Singh, Joseph H. McCarthy, D.M. Ashley, W. Yung, Vinay K. Puduvalli, Guy Nir, Jeffrey S. Weinberg, Linghua Wang, Keith L. Ligon, G. Genovese, Peter Van Loo, P. Futreal, Jason T. Huse, Jesse R. Dixon, Frederick F. Lang, Kadir C. Akdemir 2025-05-21 bioRxiv 0 50
visibility_off Examining the Role of Extrachromosomal DNA in 1,216 Lung Cancers Azhar Khandekar, P. Hoang, J. Luebeck, M. Díaz-Gay, Wei Zhao, John P. McElderry, Caleb Hartman, Mona Miraftab, Olivia W. Lee, Kara M. Barnao, E. Bergstrom, Yang Yang, Martin A. Nowak, Nathaniel Rothman, Robert J Homer, S. Yang, Qing Lan, David C Wedge, Lixing Yang, Stephen J Chanock, Tongwu Zhang, Ludmil B. Alexandrov, Marion Landi 2025-06-07 bioRxiv 0 19
visibility_off Mitotic BLM functions are required to maintain genomic stability Tamara Eleanore Hamann, A. Wieland, Andrea Tirincsi, Kruno Vukušić, Farbod Mohseni, René Wardenaar, Marialucrezia Losito, Ipek Ilgin Gönenc, B. Wollnik, F. Foijer, I. Tolic, Zuzana Storchová, M. Räschle 2025-06-16 bioRxiv 0 36
visibility_off Methylation aberrations and genomic instability synergistically drive the evolution of intrahepatic cholangiocarcinoma Guanghao Li, Youhuang Bai, Feng Tao, Tingting Hu, Ting Wang, Yong Zeng, Deqiang Sun 2025-06-17 Epigenomics 0 0
visibility_off An Enhancement of Extrachromosomal Circular DNA Enrichment and Amplification to Address the Extreme Low Overlap Between Replicates Charles M. Burnham, Alongkorn Kurilung, Visanu Wanchai, Birgritte Regenberg, J. Delgado-Calle, Alexei G. Basnakian, I. Nookaew 2025-07-07 bioRxiv 0 11
visibility_off Oncogenic lncRNA transgene transcription modulates epigenetic memory at a naïve chromosomal locus Sweta Sikder, Songjoon Baek, Yamini Dalal, Ganesan Arunkumar 2025-05-19 bioRxiv 0 4
visibility_off KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival Thomas L. Ekstrom, Zhangshuai Dai, Julia Thiel, Meghana Manjunath, Nadine Schacherer, Bishakha Joyeeta Saha, Yara Souto, A. Abdelrahman, Frank Essmann, Sven Beyes, M. Truty, Meng Dong, Steven A. Johnsen 2025-07-08 bioRxiv 0 42
visibility_off Effect of extrachromosomal DNA (ecDNA) on MYCN amplified neuroblastoma and patient outcomes. Mihika Sonalkar, Carla Sampaio, Ting Yang, Taelor Getz, Catherine Shaw, Vicky Pham, Joshua Lange, Sudhir Chowdhry, Christian A Hassig, L. Alexandrov, Peter E. Zage 2025-06-01 Journal of Clinical Oncology 0 80
visibility_off Spatio-temporal chromosomal arrangements by late-replicating heterochromatin Satyadev Polisetty, Shuvadip Dutta, Rakesh Netha Vadnala, D. Notani, R. Padinhateeri, K. Sanyal 2025-06-17 bioRxiv 0 28
visibility_off CREPT is required for the metastasis of triple-negative breast cancer through a co-operational-chromatin loop-based gene regulation Jianghua Li, Lu Xu, Jiayu Wang, Xuning Wang, Yuting Lin, Alex Yutian Zou, Fangli Ren, Yinyin Wang, Jun Li, Zhijie Chang 2025-06-10 Molecular Cancer 0 3
visibility_off The class II myosin MYH4 safeguards genome integrity and suppresses tumor progression J. Thatte, Ana Moisés da Silva, Judit Börcsök, Thorkell Gudjónsson, Jan Benada, Xin Li, Muthiah Bose, H. van der Gulden, Ji-Ying Song, Renée Menezes, Elena Martín-Doncel, Luis Toledo, Valdemaras Petrosius, Cord Brakebusch, J. Jonkers, F. C. Nielsen, Maria Rossing, C. S. Sørensen 2025-06-02 The Journal of Clinical Investigation 0 14
visibility_off 3D genome organization shapes DNA damage susceptibility to platinum-based drugs Ye Wang, Aslı Yıldırım, L. Boninsegna, Valentina Christian, Sung-Hae L Kang, X. J. Zhou, Frank Alber 2025-05-22 Nucleic Acids Research 0 10
visibility_off Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma A. Modrek, Ken Chandradoss, Catherine Do, R. Ezhilarasan, Theodore Sakellaropoulos, Jerome Karp, Yingwen Ding, Ze-Yan Zhang, Melanie Graciani, Giulia Cova, Jennifer E. Phillips-Cremins, Erik P. Sulman, Jane A. Skok 2025-06-24 bioRxiv 0 22
visibility_off LSH-mediated resolution of R-loops mitigates transcription-replication conflicts to preserve genomic stability in prostate cancer cells Kai Ni, Yu Zhang, Kun Zheng, Jianwen Huang, Nuorong Xiong, Rong Liang, Yingxiao Chen, Honglin Jin, Youlong Hai, Wang Li, Jiayi Ma, Ranxing Yang, Guanggai Xia, Yueqing Bai, Lujie Song, Xiaoyong Hu, Zijian Tang, Qiang Fu 2025-06-07 bioRxiv 0 10
visibility_off Cancer type-specific association of p53 deficiency with aneuploidy and chromosome losses Joana F. Marques, Marco António Dias Louro, Teresa Davoli, G. Kops 2025-07-07 bioRxiv 0 63
visibility_off ANP32E drives vulnerability to ATR inhibitors by inducing R-loops-dependent transcription replication conflicts in triple negative breast cancer Sara Lago, V. Poli, Lisa Fol, Mattia Botteon, Federica Busi, Alice Turdo, Miriam Gaggianesi, Yari Ciani, Giacomo D’Amato, Luca Fagnocchi, A. Fasciani, F. Demichelis, Matilde Todaro, A. Zippo 2025-05-17 Nature Communications 0 21
visibility_off Irradiation-induced increase in nuclear p62 levels contributes to chromosomal fragmentation and chromothripsis. Xiaojuan Yang, Ying Zhou, Buzhe Zhang, Xue Tao, Weili Qi, Hong Wu 2025-06-05 International journal of surgery 0 1
visibility_off Cell enlargement causes mitotic errors and aneuploidy in cells that evade senescence after CDK4/6 inhibition Aanchal U. Pareri, Marialucrezia Losito, F. Foijer, AT Saurin 2025-07-07 bioRxiv 0 36
visibility_off Principles and functional consequences of plasmid chromatinization in mammalian cells Ben Mallory, Thomas W. Tullius, Carina G. Biar, Jonas A. Gustafson, Stephanie C. Bohaczuk, Danilo Dubocanin, L. Starita, A. Stergachis 2025-05-30 bioRxiv 0 20
visibility_off What the VAF? A guide to the interpretation of variant allele fraction, percent mosaicism, and copy number in cancer Adam C Smith, Hubert Tsui, Sila Usta, Jose-Mario Capo-Chichi 2025-07-08 Molecular Cytogenetics 0 16
visibility_off Genomic characterization of repetitive DNA and transposable elements in Dyckia (Pitcairnioideae) species João Victor da Silva Rabelo-Araujo, A. F. Francisconi, Zirlane Portugal da Costa, Caroline Bertocco Garcia, Otavio Batista de Castro Ribeiro, Ana Cristina Silva Amoroso Anastacio, Maria Imaculada Zucchi 2025-07-09 BMC Research Notes 0 4
visibility_off Molecular profiling of head and neck cancers (HNCs): Genetic heterogeneity, immune landscape, and therapeutic targets. R. K. Choudhary, S. Limaye, Padman Vamadevan, Vivek Agarwala, Vikas Goswami, H. P, Vijay Anand Reddy, Niyati Krunal Shah, Darshit Kalpeshkumar Shah, Shivam Shingla, Dhanashri Ahire, Vinayak Rao, R. Gosavi, Priyanka Desale, R. Datar, D. Patil 2025-06-01 Journal of Clinical Oncology 0 7
visibility_off Mechanisms of efficacy of endonuclease inhibition in neuroblastoma. Carla Sampaio, Eric Wu, Madison Cinelli, Erica Steen, Andrew Shiau, Richard Kolodner, Jean Yin Jen Wang, Peter E. Zage 2025-06-01 Journal of Clinical Oncology 0 2
visibility_off Mitotic phosphorylation of ADAR1 regulates its centromeric localization and is required for faithful mitotic progression Yuxi Yang, Mai Kubota, Kokone Hasegawa, Chao Zeng, Kazuko Nishikura, Michiaki Hamada, Masayuki Sakurai 2025-05-29 bioRxiv 0 8
visibility_off Transcription-Replication Conflicts: Unlocking New Frontiers in Cancer. Aleix Bayona-Feliú, A. Aguilera 2025-06-09 BioEssays : news and reviews in molecular, cellular and developmental biology 0 7
visibility_off The landscape and consequences of transcription stress Osama Hidmi, Sara Oster Flayshman, Diala Shatleh, Jonathan Monin, Rami I. Aqeilan 2025-05-25 bioRxiv 0 4
visibility_off Tumor ploidy determination in low-pass whole genome sequencing and allelic copy number visualization using the Constellation Plot Sarah H. Johnson, J. Smadbeck, Roman M. Ženka, Michael T. Barrett, Athanasios Gaitatzes, Arnav Solanki, Angela B. Florio, M. Borad, John C. Cheville, G. Vasmatzis 2025-05-20 Genome Biology 0 62
visibility_off Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas Michelle G. Webb, Frances Chow, Carmel G. McCullough, Bohan Zhang, John J. Y. Lee, Rania Bassiouni, Norman E. Garrett, Kyle Hurth, J. Carpten, Gabriel Zada, David W. Craig 2025-06-13 Nature Communications 0 75
visibility_off Nucleosome-mediated conformational switches in micro-eccDNAs Sarah Harris, Victor Velasco Berrelleza, William Sandel, T. Sutthibutpong, Victoria N. Parikh, Euan A. Ashley, Andrew Fire, S. Levene, Thomas C Bishop, M. Shoura 2025-06-18 bioRxiv 0 21
visibility_off Role of PLK4 inhibition in cancer therapy. Kishore Banik, Thomas J Hayman 2025-06-13 Cancer metastasis reviews 0 0
visibility_off Half the Chromosome It Used to Be: Identifying Cancer Treatments Targeting Aneuploid Losses Andrew O. Disharoon, Joe R. Delaney 2025-06-01 Genes 0 1
visibility_off Disruption of TAD hierarchy promotes LTR co-option in cancer. Elissa W P Wong, Merve Sahin, Rui Yang, UkJin Lee, Dan Li, Y. Zhan, Rohan Misra, Fanny Tomas, Nawaf Alomran, A. Polyzos, Cindy J. Lee, Tuan Trieu, A. Martínez-Fundichely, Thomas Wiesner, Andrew Rosowicz, Shuyuan Cheng, Christina Liu, Morgan Lallo, A. Shoushtari, T. Merghoub, Pierre-Jacques Hamard, R. Koche, Ekta Khurana, E. Apostolou, Deyou Zheng, Yu Chen, Christina S. Leslie, Ping Chi 2025-06-30 Nature genetics 0 83
visibility_off Small intestinal neuroendocrine tumors lack early genomic drivers, acquire DNA repair defects and harbor hallmarks of low REST expression Felix Bolduan, Niklas Müller-Bötticher, Olivia Debnath, I. Eichhorn, Yvonne Giesecke, Alexandra Wetzel, S. Sahay, Tomasz Zemojtel, Marten Jaeger, Ute Ungethuem, Christoph Roderburg, C. A. Kunze, Annika Lehmann, David Horst, Frank Tacke, Roland Eils, Bertram Wiedenmann, Michael Sigal, N. Ishaque 2025-05-23 Scientific Reports 0 10
visibility_off Prognostic impact and racial disparities of chromosome 8q gains in prostate cancer: Insights from integrated molecular profiling. Chidiebube J. Ugwu, G. Laliotis, U. C. Okere, Nneoma Ubah, Elvis Obomanu, Colton Jones, Muluken Megiso, Nzubechukwu J. Ugochukwu, Gabor Varadi 2025-06-01 Journal of Clinical Oncology 0 6
visibility_off Abstract PS9-05: Somatic Structural Variation in Breast Cancer and its Application in Longitudinal Analysis of Circulating Tumor DNA in Early Breast Cancer M. Elliott, Karen Howarth, S. Main, J. F. Antrás, Philippe Echelard, Aaron Dou, Eitan Amir, M.B. Nadler, Elizabeth Shah, Celeste Yu, Scott V. Bratman, Taylor Bird, June Roh, Elza C de Bruin, Christopher Rushton, Sofia Birkeälv, M. Alcaide, L. Oton, Sergii Gladchuk, Yilun Chen, A. George, Girish Putcha, Samuel Woodhouse, P. Bedard, Lillian L. Siu, H. Berman, D. Cescon 2025-06-13 Clinical Cancer Research 0 48
visibility_off Nuclear Phase Separation Drives NPM1-mutant Acute Myeloid Leukemia Gandhar K. Datar, Elmira Khabusheva, Archish Anand, Joshua Beale, Marwa Sadek, Chun-Wei Chen, Evdokiia Potolitsyna, Nayara Alcantara-Contessoto, Guangyuan Liu, Josephine De La Fuente, Christina Dollinger, A. Guzman, Alejandra G Martell, Katharina Wohlan, A. Maiti, N. Short, S. S. Yi, V. Andresen, Bjørn T. Gjertsen, B. Falini, R. E. Rau, L. Brunetti, Nidhi Sahni, M. Goodell, Joshua A. Riback 2025-05-28 bioRxiv 0 83
visibility_off Enhancer RNA–mediated transcriptional regulatory programs reveal the malignant progression of glioma Yingying Ma, Shuyuan Wang, Yijie Jia, Shijie Wang, Wendian Liu, Jiaxin Yu, Jun Wang, Jingkai Geng, Jiayi Zhao, Zheng Zhao, Juan Xu, Hui Liu 2025-06-06 Science Advances 0 3
visibility_off DNA2 and FANCM function in two distinctive pathways in disrupting TERRA R-loops and suppressing replication stress at ALT telomeres Ashwin Ragupathi, Heba Z. Abid, Yun Chen, Rongwei Zhao, Settapong T. Kosiyatrakul, Derin I. Yetil, Julia Neiswander, Rachel Feltman, Shannon Thomas, Benjamin Yusupov, Manrose Singh, Li Zheng, Binghui Shen, Huaiying Zhang, H. C. Chu, Carl L. Schildkraut, Ming Xiao, Dong Zhang 2025-05-24 bioRxiv 0 30
visibility_off Transcription factors overcome the repressive impact of Polycomb-associated methylation in tumors Min-Kyeong Kwon, Goeun Park, Dayoung Go, Donghyun Park, Sridhar Hannenhalli, Sun Shim Choi 2025-05-19 bioRxiv 0 2
visibility_off Die Vermessung des Genoms Clemens Steinek, H. Leonhardt 2025-06-01 BIOspektrum 0 4
visibility_off Cytogenetics and Cytogenomics in Clinical Diagnostics: Genome Architecture, Structural Variants, and Translational Applications Concetta Federico, Desiree Brancato, Francesca Bruno, Elvira Coniglio, V. Sturiale, Salvatore Saccone 2025-06-30 Genes 0 29
visibility_off Scaling laws of bacterial and archaeal plasmids Rohan Maddamsetti, Irida Shyti, Maggie L. Wilson, Hye-in Son, Yasa Baig, Zhengqing Zhou, Jia Lu, Lingchong You 2025-07-02 Nature Communications 0 14
visibility_off Single-cell Characterization of DNA Hydroxymethylation of the Mouse Brain During Aging Yali Bai, Tianjiao Yuan, Liuhao Ren, Yuhang Huan, Fa Yang, Yutong Li, Aicui Zhang, Yueyang Liu, Tian Tian, Ningxia Kang, Danni Chen, Xuchao Xie, Qiang Wang, Wei Chen, Yinghui Zheng, Xiaoliang Sunney Xie, Yunlong Cao 2025-06-01 bioRxiv 0 4
visibility_off Molecular Phenotypic Plasticity Informs Possible Adaptive Change of Triple-Negative Breast Cancer Cells In Vivo Md. Iftehimul, P. Muganda, Robert H. Newman, C. J. Rorie, Scott H. Harrison, M. T. Hossain, Misty D. Thomas, Joseph L. Graves, Dipongkor Saha 2025-06-03 bioRxiv 0 8
visibility_off Senescence-Associated Chromatin Rewiring Promotes Inflammation and Transposable Element Activation A. Dalgarno, Shane A. Evans, M. Kelsey, Thomas A. Nunez, Azucena Rocha, Kelly Clark, J. Sedivy, Nicola Neretti 2025-06-17 bioRxiv 0 8
visibility_off TEITbase: a database for transposable element (TE)-initiated transcripts in human cancers Yun Zhang, Jianqi She, Xueyan Hu, Yueqi Jin, Changyu Tao, Minghao Du, Ence Yang 2025-06-25 bioRxiv 0 7
visibility_off Abstract P5-06-26: APOBEC3B And DNA Damage Repair As Synthetic Lethal Pairs B. Stefanovska, Benjamin Troness, Kevin Lin, Chad Myers, R. Harris 2025-06-13 Clinical Cancer Research 0 73
visibility_off R-2-hydroxyglutarate-mediated inhibition of KDM4A compromises telomere integrity Florence Couteau, Laurence M Gagné, Karine Boulay, Philippe Rousseau, Mélissa Carbonneau, Mary McQuaid, Jyoti Sharma, C. Sawchyn, Erlinda Fernandez, Dagmar Glatz, Rana Rizk, Marie-Eve Lalonde, Yosra Mehrjoo, Tsz Wai Chu, G. Moquin-Beaudry, Christian Beauséjour, Mikhail Sergeev, Santiago Costantino, D. Avizonis, I. Topisirovic, Nada Jabado, Hugo Wurtele, Chantal Autexier, Frédérick A. Mallette 2025-06-06 Nucleic Acids Research 0 61
visibility_off Role of Chromosomal Microarray and RNA Fusion Analysis in Detecting KMT2A Partial Tandem Duplication with High Mortality in Myeloid Neoplasms: Retrospective Study MD¹ Bhaumik Shah, MD¹ Jianming Pei, MD¹ Roniya Francis, MD² Peter Abdelmessieh, MD¹ Mariusz Wasik, MD¹ Nicholas Mackrides, MD¹ Reza Nejati 2025-05-28 None 0 0
visibility_off C-myc Oncogene Numerical Imbalances Analysis in Laryngeal Squamous Cell Carcinoma Sotirios Papouliakos, V. Papanikolaou, A. Chrysovergis, E. Tsiambas, D. Roukas, Sofianiki Mastronikoli, G. Tsouvelas, G. Agrogiannis, Nikolaos Kavantzas, Vasileios Ragos, Andreas C. Lazaris, E. Kyrodimos 2025-05-27 AntiCancer Research 0 30
visibility_off Uncovering a Novel Role of ROR1 in the Epigenetic Regulation of Tumor Suppressor Gene CREB3L1 in Triple-Negative Breast Cancer Cells Victoria L. Reed, Eric Lalu, Leena Yoon, Norman Fultang, B. Peethambaran 2025-05-01 Biomolecules 0 12
visibility_off Exploring the roles of conserved context-dependent cis-regulatory elements (cdCREs) in multicellularity, human health and disease. Andrew McEwan, Alexander Rattray, Greg Hutchings, Elizabeth A. Hay, Chris Murgatroyd, A. MacKenzie 2025-07-04 The FEBS journal 0 18
visibility_off ECCFP: a consecutive full pass based bioinformatic analysis for eccDNA identification using Nanopore sequencing data Tangxuan Zhang, Wang Li, Qingsong Zen, Jun Zhang, Biyuan Miao, Mengting Li, Juan Luo, Tianliang Liu, Shifu Chen, Shaogui Wan 2025-05-16 bioRxiv 0 1
visibility_off Longitudinal and multisite sampling reveals mutational and copy number evolution in tumors during metastatic dissemination. K. Zhao, J. Vos, S. Lam, Lillian A Boe, Daniel Muldoon, Catherine Y Han, Cristina Valero, Mark Lee, C. Fitzgerald, A. Lee, Manu Prasad, Swati Jain, Xinzhu Deng, Timothy A Chan, Michael F. Berger, C. Bandlamudi, Xi Kathy Zhou, Luc G. T. Morris 2025-06-02 Nature genetics 0 25
visibility_off From cytogenetics to proteogenomics: new horizons in the study of aneuploidies K. Zadesenets, N. B. Rubtsov 2025-06-01 Vavilov Journal of Genetics and Breeding 0 12
visibility_off Integrated Spatial Analysis of Ovarian Precancerous Lesions Tu-Yung Chang, Yen-Wei Chien, Szu-Hua Chen, Annelise Sokolow, Yeh Wang, Brant G. Wang, Tricia A Numan, M. Herman Chui, Rebecca Stone, T. Pisanic, Nicholas Papadopoulos, Tian-Li Wang, Christopher Douville, Leslie Cope, I.-M. Shih 2025-06-27 bioRxiv 0 73
visibility_off Biological roles of enhancer RNA m6A modification and its implications in cancer Yangyang Han, Jingqi Sun, Minghui Yao, L. Miao, Mengjia Li 2025-05-30 Cell Communication and Signaling : CCS 0 1
visibility_off A survey of human cancer-germline genes : linking X chromosome localization, DNA methylation and sex-biased expression in early embryos A. Loriot, Julie Devis, Laurent Gatto, C. De Smet 2025-05-23 bioRxiv 0 21
visibility_off Epigenetic Subtypes of High-Grade T1 Bladder Cancer Reveal Intra-Tumor Heterogeneity and Distinct Interactions with Tumor Microenvironment J. Bellmunt, Yingtian Xie, N. Juanpere, M. Munoz, Shweta Kukreja, Sonsoles Liria Veiga, Rong Li, Xintao Qiu, Yijia Jiang, Alba Font-Tello, Marie Nunez Duarte, Ilana B. Epstein, Silvia Hernández-Llodrà, Marta Lorenzo, Silvia Menendez, T. Choueiri, Myles Brown, H. Long, Paloma Cejas 2025-06-20 bioRxiv 0 26
visibility_off Sequence diversity lost in early pregnancy G. Arnadottir, Hákon Jónsson, T. Hartwig, J. Gruhn, P. L. Møller, Arnaldur Gylfason, D. Westergaard, Andrew Chi-ho Chan, A. Oddsson, L. Stefánsdóttir, L. Roux, V. Steinthorsdottir, Kristjan H Swerford Moore, S. Olafsson, Pall I. Olason, H. Eggertsson, G. Halldorsson, G. Walters, H. Stefánsson, S. A. Gudjonsson, G. Pálsson, B. Jensson, Run Fridriksdottir, Jesper Friis Petersen, , H. Nielsen, S. Bliddal, K. Banasik, M. Krog, A. Kolte, N. la Cour Freiesleben, S. Ostrowski, Erik Sørensen, Mille Løhr, Markus J. Herregård, E. Hoffmann, J. Gruhn, Andrew Chi-ho Chan, U. Þorsteinsdóttir, Kári Stefánsson, Hákon Jónsson, O. Magnusson, L. Ambye, Lone Schmidt, P. Kamstrup, M. Nyegaard, Ellen Christine Leth Løkkegaard, H. E. Bredkjær, H. W. Hvidman, Agnar Helgason, G. Norddahl, P. D. Rohde, J. Saemundsdottir, O. Magnusson, B. Halldórsson, D. Gudbjartsson, P. Sulem, U. Thorsteinsdóttir, E. Hoffmann, H. Nielsen, Kári Stefánsson 2025-05-21 Nature 2 184
visibility_off FAM72A promotes UNG2 degradation and mutagenesis in human cancer cells Yuqing Feng, P. Barbulescu, Chetan K Chana, Melika Shirdarreh, Hong Yang, Lizhen Wu, Sami Mamand, Mohammad Kashem, Amin Zia, Ming Han, Julissa Tsao, Trevor Pugh, David Cescon, David G. Schatz, Frank Sicheri, Alberto Martin, R. Pezo 2025-07-02 Scientific Reports 0 13
visibility_off Conserved cell state dynamics reveal targetable resistance patterns in ovarian high-grade serous carcinoma A. Pirttikoski, Laura Gall-Mas, Wojciech Senkowski, David Fontaneda-Arenas, Matias Marin Falco, E. Erkan, J. Hynninen, K. Wennerberg, Anna Vähärautio 2025-06-18 bioRxiv 0 60
visibility_off Competing Subclones and Fitness Diversity Shape Tumor Evolution Across Cancer Types Haiming Chen, Jingmin Shu, Rekha Mudappathi, Elaine Li, Panwen Wang, Leif Bergsagel, Ping Yang, Zhifu Sun, Logan Zhao, Changxin Shi, Jeffrey P. Townsend, Carlo Maley, Li Liu 2025-06-03 bioRxiv 0 5
visibility_off Evaluating topography of mutational signatures with SigProfilerTopography Burçak Otlu, Ludmil B. Alexandrov 2025-05-20 Genome Biology 1 9
visibility_off The epigenetic regulator TRIM24 controls melanoma cell dedifferentiation and resistance to treatment in melanoma Simon Durand, Félix Boivin, Roxane M. Pommier, L. Barbollat-Boutrand, Maxime Grimont, Félix Pham, Marion Dufeu, Eric Cumunel, Raphaël Schneider, Anthony Ferrari, Anaïs Eberhardt, Stéphane Dalle, J. Caramel 2025-05-24 bioRxiv 0 18
visibility_off Constitutional copy number amplifications: rare or under-evaluated? Revisiting a 25-year-old cold case. Eliana Salvo, Romano Tenconi, R. Giorda, Sara Bertuzzo, Luca Cesana, Roberta Murru, S. Giglio, Mana M Mehrjouy, Niels Tommerup, Orsetta Zuffardi, M. Bonaglia 2025-06-04 European journal of human genetics : EJHG 0 49
visibility_off Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer Li-Yang Wang, Ji Shi, Mo-Fei Wang, Yi-Meng Liu, Hong-Shan Guo, Jin-Cheng Wang, Shu Jiang, Jia-Qian Liang, Xinghua Liao, Shao-Yong Chen 2025-05-22 Scientific Reports 0 1
visibility_off Epigenetic silencing and genome dynamics determine the fate of giant virus endogenizations in Acanthamoeba Cédric Blais, Morgan J. Colp, Luke A. Sarre, Alex de Mendoza, John M. Archibald 2025-07-01 BMC Biology 0 22
visibility_off RecN and RecA orchestrate an ordered DNA supercompaction response following ciprofloxacin-induced DNA damage in Escherichia coli. Krister Vikedal, S. B. Ræder, Ida Mathilde Marstein Riisnæs, Magnar Bjørås, J. Booth, Kirsten Skarstad, Emily Helgesen 2025-05-22 Nucleic acids research 0 8
visibility_off ONECUT2 reprograms neuroendocrine fate and is an actionable therapeutic target in small cell lung cancer Mirian Gutiérrez, Irene Zamora, Raquel Iriarte, M. Pajares, Qian Yang, Chen Qian, N. Otegui, J. Fernández-Irigoyen, Enrique Santamaria, N. Alcala, A. Sexton-Oates, L. Fernandez-Cuesta, Miguel Barajas, Alfonso Calvo, Luis M. Montuenga, Beatrice S. Knudsen, Sungyong You, Michael R. Freeman, Ignacio J. Encío, Mirja Rotinen 2025-06-11 Molecular Medicine 0 37
visibility_off A new IDH-independent hypermethylation phenotype is associated with astrocyte-like cell state in glioblastoma Ana Luisa Costa, Daria Doncevic, Yonghe Wu, Lin Yang, Ka-Hou Man, Anna-Sophie Spreng, Hannah Winter, M. Fletcher, B. Radlwimmer, Carl Herrmann 2025-07-03 Genome Biology 0 66
visibility_off Actionable biological programs to enhance EGFR-targeted therapy response unveiled by single-cell lineage tracing in clinically relevant lung cancer models Beatrice Gini, W. Tamaki, Johnny Yu, Dora Barbosa, Wei Wu, Yashar K Pourmoghadam, Paul Allegakoen, Donghwa Kim, S. Miglani, Sarah Elmes, V. Olivas, Hani Goodarzi, T. Bivona 2025-05-23 bioRxiv 0 60
visibility_off Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer Heather Karner, Tabea Mittmann, Vicky W. Chen, Ashir A. Borah, Andreas Langen, Hassan Yousefi, L. Fish, Balyn W. Zaro, A. Navickas, Hani Goodarzi 2025-06-07 bioRxiv 0 20
visibility_off Detecting hotspots of intra- and transchromosomal fusions in liposarcomas by RNA sequencing. Dmitrii Grachev, Danil Ivanov, Oleg Baranov, Vladimir Kushnarev, Melissa Clemons, Sheila T. Yong, N. Kotlov, Konstantin Chernyshov, A. Bagaev, N. Fowler, A. Conley, G.M. Cote, Sant P Chawla 2025-06-01 Journal of Clinical Oncology 0 12
visibility_off Clinicopathologic and allele-specific analysis of germline ATM alterations in a pan-cancer cohort. Matteo Repetto, Daniel Muldoon, P. Selenica, Kanika Arora, Ying L. Liu, M. Carlo, Lauren Banaszak, Alicia J Latham, C. Bandlamudi, E. O'Reilly, M. E. Robson, B. Rousseau, D. Mandelker, A. Drilon, Britta Weigelt, K. Offit, Michael F. Berger, Y. Murciano-Goroff, Z. Stadler, Mohammad Abbass 2025-06-01 Journal of Clinical Oncology 0 131
visibility_off A dynamic molecular landscape in colorectal cancer progression at single-cell resolution Jianwen Sheng, Nianshuang Li, Shuai Li, Yuman Ye, Yuanhang Liao, Yupeng Zhang, Huan Chen, Mengxian Tu, Guping Zhong, Chaoliang Xiong, Pan Zheng, Yuting Lei, Zekun He, Xingxing He, Yao Zhang, Lei Wang, Xiaolin Gao, Yin Zhu, Jianping Liu, Huizhen Fan 2025-07-01 Journal of Translational Medicine 0 4
visibility_off MYC: The Guardian of Its Own Chaos A. Gaballa, Bastian Krenz, Leonie Uhl 2025-06-09 Bioessays 1 5
visibility_off Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12 Selina Troester, Thomas Eder, Nadja Wukowits, M. Piontek, P. Fernández-Pernas, Johannes Schmoellerl, B. Haladik, G. Manhart, M. Allram, Margarita Maurer-Granofszky, Nastassja Scheidegger, K. Nebral, Giulio Superti-Furga, Roland Meisel, B. Bornhauser, P. Valent, Michael N Dworzak, Johannes Zuber, Kaan Boztug, Florian Grebien 2025-05-19 Nature Communications 0 36
visibility_off The role of pioneering transcription factors, chromatin accessibility and epigenetic reprogramming in oncogenic viruses M. Kgatle, S. Mbambara, Leon Khoza, Olalekan Fadebi, T. Mashamba-Thompson, M. Sathekge 2025-06-16 Frontiers in Microbiology 0 28
visibility_off LINE-1 ORF1p is a shared and immunogenic antigen in cancer Wilson McKerrow, Megan Snyder, Chong Chu, Deena Kelly, Heike Keilhack, Liyang Diao 2025-06-17 bioRxiv 0 1
visibility_off Genomic alterations in the YAP/TAZ pathway are associated with stem cell-like castration-resistant prostate cancer M. Roskes, A. Martínez-Fundichely, S. Cohen, M. Balaban, C. K. Wong, W. Li, T. A. Gonzalez, A. Tehim, H. Xu, S. ElNaggar, M. Myers, R. Bareja, P. Dorsaint, K. Gorski, M. Asad, M. A. Assaad, B. D. Robinson, M. Sigouros, E. Barnett, J. Manohar, S. Tagawa, D. Nanus, A. Molina, J. Nauseef, C. N. Sternberg, J. Mosquera, H. Scher, A. Sboner, B. Raphael, Y. Chen, E. Khurana 2025-07-02 medRxiv : the preprint server for health sciences 0 69
visibility_off CRISPR activation screens map the genomic landscape of cancer glycome remodeling John Daly, Lidia Piatnitca, Mohammed Al-Seragi, Vignesh K Krishnamoorthy, S. Wisnovsky 2025-05-27 bioRxiv 1 11
visibility_off Upregulated BAP31 Links to Poor Prognosis and Tumor Immune Microenvironment in Breast Cancer Z. Hao, Bo Zhao, Xiaoshuang Zhu, Wanting Zhang, Bing Wang 2025-06-21 International Journal of Molecular Sciences 0 7
visibility_off Leveraging Whole-Exome Sequencing and Mutational Signatures to Detect Homologous Recombination Deficiency in Cancer. Joonoh Lim, Young Seok Ju 2025-07-02 Cancer research 0 6
visibility_off PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment Hong-xing Li, Xiao-ling Ma, Wang-bin Ma, Tian-yu Jia, Xiao-Hong Sun, Xiao-Xia He, Li-li Zhang, Ya-Ming Xi 2025-06-18 Frontiers in Immunology 0 1
visibility_off Caspase-8 is a novel modulator of Homologous Recombination Repair in response to ionizing radiations Alessandra Ferri, Claudia Contadini, Claudia Di Girolamo, C. Cirotti, G. Fiscon, Paola Paci, M. Marzullo, M. Gentileschi, Tatsuro Yamamoto, Robert Strauss, D. Del Bufalo, L. Ciapponi, D. Barilà 2025-05-29 bioRxiv 0 39
visibility_off Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer. Elena Grassi, V. Vurchio, George D. Cresswell, Irene Catalano, B. Lupo, F. Sassi, Francesco Galimi, Sofia Borgato, Martina Ferri, Marco Viviani, Simone Pompei, Gianvito Urgese, Bingjie Chen, E. Zanella, F. Cottino, Mariangela Russo, G. Mauri, F. Pietrantonio, M. G. Zampino, L. Lazzari, S. Marsoni, A. Bardelli, M. Lagomarsino, A. Sottoriva, L. Trusolino, Andrea Bertotti 2025-05-21 Science translational medicine 0 66
visibility_off Genome-wide maps of UV damage repair and mutation suppression by CPD photolyase Kaitlynne A. Bohm, Marian F. Laughery, P. A. Mieczkowski, Steven A. Roberts, John J Wyrick Data Curation 2025-06-06 Nucleic Acids Research 0 10
visibility_off Spatial joint profiling of DNA methylome and transcriptome in mammalian tissues Chin Nien Lee, Hongxiang Fu, Angelysia Cardilla, Wanding Zhou, Yanxiang Deng 2025-07-04 bioRxiv 0 4
visibility_off EGR1 drives sex-differences in glioblastoma tumorigenicity Tamara J. Abou-Antoun, Lorida Llaci, Jason P. Wong, Lihua Yang, N. Warrington, Lloyd Tripp, Jingqin Luo, Brian D. Muegge, Joshua B. Rubin, R. Mitra 2025-05-21 bioRxiv 0 49
visibility_off Abstract P2-06-27: Mapping APOBEC Profiles in Breast Cancer Microenvironments: Bridging Bulk and Single-Cell RNA-seq Data Jake Lehle, Mohadeseh Soleimanpour, Diako Ebrahimi 2025-06-13 Clinical Cancer Research 0 5
visibility_off Genome-wide extraction of differentially methylated DNA regions using adapter-anchored proximity primers Farzaneh Darbeheshti, Hayet Radia Zeggar, Hamzeh Salmani, Yibin Liu, Ruolin Liu, V. Adalsteinsson, G. M. Makrigiorgos 2025-06-30 bioRxiv 0 25
visibility_off Exploring the m5C epitranscriptome of mRNAs in breast cancer cells through genome engineering and long-read sequencing approaches Konstantina Athanasopoulou, P. Adamopoulos, P. Tsiakanikas, Andreas Scorilas 2025-06-25 Functional & Integrative Genomics 0 16
visibility_off Genetic barcoding uncovers the clonal makeup of solid and liquid biopsies and their ability to capture intra-tumoral heterogeneity A. Serrano, Tom S. Weber, J. Berthelet, Sarah Ftouni, Farrah El-Saafin, Verena C. Wimmer, K. Rogers, Elgene Lim, Emmanuelle Charaffe-Jauffret, Christophe Ginestier, David Williams, Frédéric Hollande, B. Yeo, Sarah-Jane Dawson, S. Naik, D. Merino 2025-06-17 bioRxiv 0 39
visibility_off SLFN11 Enhances Cisplatin Sensitivity in Pediatric Cancer via Activation of Stress-Response and Suppression of Survival Pathways A. Jabeen, Dina Awartani, S. Sherif, Eiman I. Ahmed, R. Alanany, Ayman Saleh, W. Hendrickx, C. Raynaud 2025-06-22 bioRxiv 0 14
visibility_off Silencing by the HUSH Epigenetic Transcriptional Repressor Complex. Paul J. Lehner 2025-06-01 Annual review of biochemistry 0 2
visibility_off Current advances in the role of classical non‐homologous end joining in hematologic malignancies Pengcheng Liu, Zi-zhen Xu 2025-05-29 Clinical and Translational Discovery 0 1
visibility_off Mitochondrial topoisomerases, nucleoid architecture and mtDNA repair in human disease. Sangheeta Bhattacharjee, B. Das 2025-07-01 Journal of cell science 0 27
visibility_off ZNF865 (BLST) Regulates Human Cell Senescence and DNA Damage Christian Lewis, H. Levis, Jonah Holbrook, Jacob T. Polaski, Timothy D. Jacobsen, S. Gullbrand, B. Diekman, J. Iatridis, Jason Gertz, Brandon Lawrence, Robert D Bowles 2025-06-18 bioRxiv 0 41
visibility_off CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential Sophia Clune, Paul Awolade, Hector Esquer, Qiong Zhou, Daniel V. LaBarbera 2025-05-30 Journal of Experimental & Clinical Cancer Research : CR 0 24
visibility_off KSHV reprograms host RNA splicing via FAM50A to activate STAT3 and drive oncogenic cellular transformation Shenyu Sun, Ling Ding, Karla Paniagua, Xian Wang, Yufei Huang, Mario A. Flores, Shou‐Jiang Gao 2025-06-12 mBio 0 5
visibility_off Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma Olivia G. Waltner, April A. Apfelbaum, Emma D. Wrenn, Shruti S Bhise, Sami B. Kanaan, R. Gladden, Mark A. Mendoza, R. Volden, Z. Kronenberg, Anand G. Patel, Michael A Dyer, J. Sarthy, Elizabeth R. Lawlor, Scott N. Furlan 2025-06-24 bioRxiv 0 10
visibility_off Gene DSCC1 is a Potential Biomarker in Pan-cancer Jialing Jiang, Xiaolong Yan, Dan Huang, Jieyu Chen, Xiaodan Hao 2025-05-29 Journal of Contemporary Medical Practice 0 0
visibility_off Abstract P1-07-17: Mitotically-associated long noncoding RNA (MANCR): A novel long noncoding RNA that promotes genomic stability and cellular proliferation in Triple Negative Breast Cancer Janine Warren, Bodhisattwa Banerjee, J. Gordon, Prachi N Ghule, Jane L. Stein, G. S. Stein, J. Lian, Peter A. Kaufman 2025-06-13 Clinical Cancer Research 0 29
visibility_off Suppression of plastid-to-nucleus gene transfer by DNA double-strand break repair Enrique Gonzalez-Duran, Xenia Kroop, Anne Schadach, Ralph Bock 2025-05-16 Nature Plants 1 6
visibility_off YAP1 promoter-associated noncoding RNA affects Ewing sarcoma cell tumorigenicity by regulating YAP1 expression L. Chellini, Arianna Del Verme, Veronica Riccioni, M. Paronetto 2025-05-25 Cellular & Molecular Biology Letters 0 39
visibility_off METTL5 Blockade Enhances Anti-Tumor Immune Response via Inducing Neoantigen Generation Yangyi Zhang, Xiaoyan Shi, Yuci Wang, Ruiqi Wang, Yanlan Cao, Hao Chen 2025-06-07 bioRxiv 0 4
visibility_off Predicting transposable element-derived neoantigens in ATRX-mutated sarcoma. Simon Cao, Ziyang Wang, B. Nacev 2025-06-01 Journal of Clinical Oncology 0 4
visibility_off Fusion oncogenes in rhabdomyosarcoma: model systems, mechanisms of tumorigenesis, and therapeutic implications Chinmay S. Sankhe, Lisa Hall, Genevieve C. Kendall 2025-06-17 Frontiers in Oncology 0 0
visibility_off Temporal and spatial coordination of DNA segregation and cell division in an archaeon Joe Parham, Valerio Sorichetti, Alice Cezanne, Baukje Hoogenberg, Sherman Foo, Yin-wei Kuo, Eloise Mawdesley, Lydia Daniels Gatward, Jerome Boulanger, Ulrike Schulze, A. Šarić, B. Baum 2025-05-29 bioRxiv 0 26
visibility_off Physical principles of phase-separation action on chromatin looping associated to pathogenic gene activation Sougata Guha, Andrea Fontana, Alex Abraham, Simona Bianco, Andrea Esposito, Mattia Conte, Sumanta Kundu, Ciro Di Carluccio, Francesca Vercellone, Florinda Di Pierno, Mario Nicodemi, A. Chiariello 2025-05-23 bioRxiv 0 21
visibility_off Deletions of LPL and NKX3.1 in Prostate Cancer Progression: Game Changers or By-Standers in Tumor Evolution Tereza Vodičková, Mária Wozniaková, Vladimír Židlík, Jana Žmolíková, Jana Dvořáčková, Adéla Kondé, Jana Schwarzerová, Michal Grepl, J. Bouchal 2025-05-24 Biomolecules 0 27
visibility_off Microhomology-Mediated End Joining as a Novel Mechanism Underlying Androgen Insensitivity Syndrome J. M. Marques, R. M. Ramos, N. D. R. D' Alessandre, G. D. A. Guardia, A. F. Afonso, B. L. Braga, M. F. D. A. Funari, M. Y. Nishi, P. Asprino, S. Domenice, P. A. F. Galante, B. B. Mendonca, R. L. Batista 2025-06-26 None 0 1
visibility_off Analyzing the relationship of RNA and DNA methylation with gene expression Shangqian Xie, Darren Hagen, G. Becker, Kimberly M. Davenport, Katie A Shira, Morgan R Stegemiller, Jacob W. Thorne, Sarem F. Khilji, D. Konetchy, Patricia Villamediana, Brenda M Murdoch, S. McKay 2025-05-22 Genome Biology 0 5
visibility_off Amplification of select autonomous HERV loci and surrounding host gene transcription in monocytes from patients with post-acute sequelae of COVID-19 Hyunmin Koo, Casey D. Morrow 2025-06-26 Frontiers in Immunology 0 15
visibility_off Cancer-associated fibroblast driven paracrine IL-6/STAT3 signaling promotes migration and dissemination in invasive lobular carcinoma Esme Bullock, Aleksandra Rozyczko, Sana Shabbir, Ifigenia Tsoupi, Adelaide I J Young, J. Travnickova, Laura Gómez-Cuadrado, Zeanap Mabruk, Giovana Carrasco, Elizabeth Morrow, K. Pennel, Pim Kloosterman, J. Houthuijzen, Jos Jonkers, L. Avalle, Valeria Poli, R. Iggo, Xue Xiao, Jingjing Guo, Xuan Zhu, Elizabeth Mallon, Joanne Edwards, E. E. Patton, Valerie G. Brunton 2025-07-01 Breast Cancer Research : BCR 0 16
visibility_off Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors Fengju Chen, Yiqun Zhang, Wei Li, F. Sedlazeck, Lanlan Shen, Chad J. Creighton 2025-05-21 Nature Communications 0 50
visibility_off Abstract P5-06-06: The Mechanistic Role of BRCA1 DNA and RAD51 Binding in DNA Double-Strand Break Repair Angela M Jasper, Hoang Dinh, Cody M Rogers, Sameer Salunkhe, Hardeep Kaur, Antoine Baudin, David S. Libich, Patrick Sung 2025-06-13 Clinical Cancer Research 0 5
visibility_off Epigenetic modifications and their roles in pediatric brain tumor formation: emerging insights from chromatin dysregulation Kento Kawata, Owen S. Chapman, Satoshi Narumi, Daisuke Kawauchi 2025-06-17 Frontiers in Oncology 0 1
visibility_off Mosaic chromosomal alterations in blood are associated with an increased risk of Alzheimer’s disease T. Naito, Kosei Hirata, Beomjin Jang, C. Lakhani, Alice Buonfiglioli, Wan-Ping Lee, O. Valladares, Li-San Wang, Yukinori Okada, Hong-Hee Won, E. Papapetrou, Samuele G. Marro, D. A. Knowles, T. Raj 2025-06-04 medRxiv 0 38
visibility_off Review: Immune Gene Regulation via cGAS-STING in ARID1A-deficient cancers and their response to therapeutic stress Syakirah Shafwah Rahmadani, Awik Puji Dyah Nurhayati 2025-05-30 International Journal of Science and Research Archive 0 0
visibility_off The Multifaceted Role of VIRMA, a Core Component of the Methyltransferase Complex, in Cancer and Cancer Therapy Jinmeng Lu, Chengyu Zhang, Mengshuang Yin, Huili You, Chao Xiong, Jing Wu, Ying Gong, Zhangang Xiao, Jing Shen 2025-06-22 Biomolecules 0 40
visibility_off Binding of Transcriptional Activator to Silent Loci Causes Their Detachment from the Nuclear Lamina in Drosophila Neurons and Salivary Gland Cells R. Simonov, O. Olenkina, V. Nenasheva, Yuri A. Abramov, Sergey A. Lavrov, A. Fedotova, Y. Y. Shevelyov 2025-06-01 International Journal of Molecular Sciences 0 13
visibility_off Gain of Function p53 mutant R273H confers distinct methylation profiles and consequent partial or full EMT states to colon tumour H. Rani, Seemadri Subhadarshini, M. Jolly, V. Mahadevan 2025-07-05 bioRxiv 0 57
visibility_off Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma Sunandini Sharma, Roshia Ali, Alyssa Bouska, Dylan Jochum, Meghana Kesireddy, Simeon Mahov, Joseph Lownik, Weiwei Zhang, Waseem G Lone, Mahfuza Afroz Soma, Alicia Gamboa, Vaishnavi Devarkonda, Dalia Elgamal, Atqiya Fariha, Adnan Mansoor, Douglas Stewart, Peter Martin, Brian K. Link, R. Advani, Paul M. Barr, A. Goy, A. Mehta, M. Kamdar, D. Stephens, Veronika Bachanova, L. Smith, Ryan D Morin, P. Pararajalingam, M. Lunning, Kai Fu, Dennis Wiesenberger, Wing C. Chan, J. Khoury, T. Greiner, J. Vose, Akil Merchant, Chengfeng Bi, J. Iqbal 2025-06-27 bioRxiv 0 111
visibility_off MYC amplification and protein expression as prognostic markers in pediatric and young adult osteosarcoma. Matthew Nagy, Olivia Puopolo, Erin Alston, Sreekar Challa, E. Ceca, Yvonne Y. Li, Andrew D Cherniack, Lorena Lazo de la Vega, A. Church, K. Janeway 2025-06-01 Journal of Clinical Oncology 0 47
visibility_off Bladder cancer subtypes exhibit limited plasticity across different microenvironments and in metastases C. Bernardo, Subhayan Chattopadhyay, Natalie Andersson, P. Eriksson, Benjamin Medle, Lena Tran, Nour Al Dain Marzouka, Adam Mattsson, Aymeric Zadoroznyj, Malin Larsson, F. Liedberg, Mattias Höglund, G. Sjödahl 2025-07-02 Experimental Hematology & Oncology 0 40
visibility_off The Primary Role of Noncoding RNA in the Pathogenesis of Cancer Amil Shah 2025-06-30 Genes 0 1
visibility_off Deficiencies in the Fanconi Anemia or the Homologous Recombination pathway enhance the antitumor effects of the novel hypoxia-activated prodrug CP-506 Lesley Schuitmaker, A. M. van der Wiel, N. Lieuwes, R. Biemans, Nikki A.M. Mutsters, Jennifer Jung, Victoria Claudino Bastos, Èlia Prades Sagarra, Sheng Kuang, S. A. Langie, J. Setton, J. Theys, A. Yaromina, Ludwig J. Dubois, P. Lambin 2025-05-24 bioRxiv 0 38
visibility_off Multimodal profiling unveils a reversible basal-like breast cancer cell state resistant to AKT inhibition Colin D. H. Ratcliffe, Hugh Sparks, G. L. Boezio, Yuriy Alexandrov, Robert P. Jenkins, A. Le Marois, Pablo Soro-Barrio, Rebecca Lee, S. Strohbuecker, Sudeep Joshi, James K. Ellis, Anne-Marie Fortier, Nils Gustafsson, Ana C. Cunha, Morag Park, J. Macrae, A. Serio, J. Briscoe, Andy Riddell, S. Barry, Chris Dunsby, E. Sahai 2025-06-07 bioRxiv 0 12
visibility_off TP53 and DNA-PK as potential biomarkers for enhanced efficacy of Olaparib in colorectal cancer. Do Yeon Kim, Hyeseon Yun, Ji-Eun You, Y. Park, Yeaseong Ryu, Dong-In Koh, Jae-Sik Shin, Dong-Hoon Jin 2025-05-16 Investigational new drugs 0 19
visibility_off XPO1R749Q Mutations Co-occur with POLE Mutations in Cancer and can be Targeted to Overcome Chemoresistance. T. Totiger, Wannasiri Chiraphapphaiboon, Y. Baca, S. Chaudhry, R. Notti, S. Montoya, M. Chojnacka, Gabriel Gaidosh, Jumana Afaghani, Maurizio Affer, Chris Armstrong, Paul M Kavanaugh, Efe Karaca, Jenna Zabroski, Michael Lewis, Alyssa Maye, Jacob Jahn, R. Soni, Daniel Bilbao, Phil Walker, Andrew Elliott, E. Lou, Wafik S. El-Deiry, Josean Rodriguez, Hai Dang Nguyen, Justin Taylor 2025-06-18 Cancer research 0 13
visibility_off The TP53 tumor suppressor gene: From molecular biology to clinical investigations Panagotis Baliakas, Thierry Soussi 2025-06-16 Journal of Internal Medicine 0 6
visibility_off Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities Jianfeng Ge, Shoko Hirosue, Saroor A. A. Patel, L. Wesolowski, Anna Dyas, Cissy Yong, Leticia Castillon, Sanne de Haan, J. Drost, Grant D. Stewart, Anna C Obenauf, D. Muñoz-Espín, Sakari Vanharanta 2025-06-20 bioRxiv 0 31
visibility_off Human TLS DNA polymerase: saviors or threats under replication stress? Y. S. Rajpurohit, Mitu Lal, D. K. Sharma, Ishu Soni 2025-05-23 Molecular and cellular biochemistry 0 15
visibility_off Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm. É. Oliveira, Salvatore Milite, J. Fernández-Mateos, George D. Cresswell, Erika Yara-Romero, G. Vlachogiannis, Bingjie Chen, Chela James, Lucrezia Patruno, Gianluca Ascolani, Ahmet Acar, Timon Heide, Inma Spiteri, Alex Graudenzi, G. Caravagna, Andrea Bertotti, Trevor A. Graham, Luca Magnani, Nicola Valeri, A. Sottoriva 2025-06-11 Cancer research 0 40
visibility_off Genotype-integrated single-cell transcriptome analysis reveals the role of DDX41 pR525H in a patient with myelodysplastic neoplasms Hirotaka Matsui, Akiko Nagamachi, Minori Koizumi, Rei Kudo, Masahiko Ajiro, H. Harada, Yuka Harada, Shigeyuki Shichino, Akihide Yoshimi 2025-07-02 Scientific Reports 0 21
visibility_off A novel role for UPF1 in safeguarding DNA replication in S phase and beyond Thomas Walne, Laura Maple, Nan Li, Isabel Christie, Carl Smythe, Ruth Thompson 2025-05-22 bioRxiv 0 1
visibility_off GenoPath: a pipeline to infer tumor clone composition, mutational history, and metastatic cell migration events from tumor DNA sequencing data Ryan M. Tobin, Shikha Singh, Sudhir Kumar, Sayaka Miura 2025-07-02 Frontiers in Bioinformatics 0 13
visibility_off From predictive biomarker to therapeutic target: the dual role of SLFN11 in chemotherapy sensitivity. Yue Feng, Yingze Li, Zhenhao Zhang, Yuxuan Dai, Xingchun Gou, Kejing Lao, Running Zhang 2025-06-18 Cancer chemotherapy and pharmacology 0 12
visibility_off EWSR1::ETS-low cells promote metabolic reprogramming of the tryptophan-kynurenine-AHR axis, immunosuppression, and poor outcome in Ewing sarcoma Martha J. Carreño-Gonzalez, Kimberley M. Hanssen, Ahmed Sadik, Alessa Henneberg, Anna C. Ehlers, A. K. Ceranski, Zuzanna Kolodynska, Malenka Zimmermann, R. Imle, Florian H. Geyer, Alina Ritter, A. Banito, M. Knott, S. Ohmura, F. Cidre-Aranaz, Christiane Opitz, T. G. Grünewald 2025-05-21 bioRxiv 0 32
visibility_off Single-cell RNA sequencing reveals the role of GTF2F2 in ovarian cancer oncogenesis and progression Haiyang Du, Gao Si, Jiqing Si, Xuejie Song, Fuchun Si 2025-05-29 Journal of Ovarian Research 0 2
visibility_off Assessment of X Chromosome Centromere Instability in Alzheimer’s Disease: A Quantitative FISH Approach B. Spremo-Potparević, Petar Popović, Dijana Topalović, Andrea Pirković, George Perry, L. Živković 2025-06-01 Current Issues in Molecular Biology 0 20
visibility_off Single-cell transcriptional dissection illuminates an evolution of immunosuppressive microenvironment during pancreatic ductal adenocarcinoma metastasis Xiaowei Liu, Jinen Song, Meiling Yuan, Fengli Zuo, Huihui Li, Leyi Tang, Xinmin Wang, Xueyan Wang, Qian Xiao, Li Li, Xinyu Liu, Zhankun Yang, Jian-Lin Wu, Jing Jing, Xuelei Ma, Hubing Shi 2025-06-09 Signal Transduction and Targeted Therapy 0 9
visibility_off Mechanism of circRNA_4083 Circularization and Its Role in Regulating Cell Viability Wenhao Li, Ting Yang, Haojie Wang, Hao Bai, Guobin Chang, Lingling Qiu 2025-05-23 Animals : an Open Access Journal from MDPI 0 3
visibility_off Spatial transcriptomics reveal PI3K-AKT and metabolic alterations in aggressive, treatment-resistant lactotroph pituitary neuroendocrine tumors F. Martinez-Mendoza, Sergio Andonegui-Elguera, E. Sosa-Eroza, Erick Gomez-Apo, Aurea Escobar-España, Carolina González-Torres, Javier Gaytán-Cervantes, Alam Palma-Guzman, Hugo Torres-Flores, Alberto Moscona-Nissan, S. Hinojosa-Alvarez, J. Hernández-Perez, R. Chavez-Santoscoy, G. Guinto, Gerardo Y. Guinto-Nishimura, B. López-Félix, Erick U. Zepeda-Fernandez, Erick M. Estrada-Estrada, V. Correa-Correa, P. A. González-Zavala, Marco A. Asenscio-Montiel, M. A. García-Vargas, Emmanuel Cantu-Chavez, Rocío Arreola-Rosales, Keiko Taniguchi-Ponciano, D. Marrero-Rodríguez, Moises Mercado 2025-05-19 Acta Neuropathologica Communications 0 17
visibility_off Dual ENPP1/ATM depletion blunts DNA damage repair boosting radioimmune efficacy to abrogate triple-negative breast cancer Borja Ruiz-Fernández de Córdoba, K. Valencia, C. Welch, Haritz Moreno, S. Martínez-Canarias, C. Zandueta, Eduardo Gómez, Alfonso Calvo, N. Otegui, M. Echepare, Ignacio Garzón, D. Ajona, David Lara-Astiaso, Elisabet Guruceaga, Laura Guembe, Ruben Pio, I. Melero, Silve Vicent, Fernando Pastor, R. Martinez-Monge, F. Lecanda 2025-06-13 Signal Transduction and Targeted Therapy 0 42
visibility_off ASXL1 truncating mutations drive leukemic resistance to T cell attack D. McCurry, Zhongqi Ge, Jaehyun Lee, Rishi Pasumarthi, Xiaohong Leng, Thomas Koehnke, O. Pasvolsky, Pranaya Raparla, Vinhkhang N. Nguyen, K. Maurer, Shuqiang Li, K. Livak, Emerie Danson, Bijal Thakkar, Elham Azizi, Robert J. Soiffer, S. Shukla, Ravi Majeti, Jerome Ritz, Catherine J. Wu, J. Molldrem, P. Bachireddy 2025-06-12 bioRxiv 0 59
visibility_off Tissue-Specific Activation of Microhomology-Mediated End Joining with Age Reflects Dynamic Rewiring of DNA Repair in Rats Diksha Rathore 2025-06-17 bioRxiv 0 0
visibility_off Inactivation of the Fusobacterium nucleatum Rnf complex reduces FadA-mediated amyloid formation and tumor development Timmie A. Britton, Ju Huck Lee, Chungyu Chang, A. Bhat, Yi-Wei Chen, Rusul Mohammed Ali, Chenggang Wu, A. Das, Hung Ton-That 2025-04-07 bioRxiv 0 29
visibility_off The role of MYEOV gene: a review and future directions Yidan Xi, Xuefei Liu, Yanan Ge, Mingzhe Jiang, Dong Zhao, Ershu Zhao, Fei Cai, Xinlong Wang, Jiatong Li, Tingting Li, Zhendong Zheng 2025-06-04 Frontiers in Oncology 0 2
visibility_off Inactivation of the Fusobacterium nucleatum Rnf complex reduces FadA-mediated amyloid formation and tumor development Timmie A. Britton, Ju Huck Lee, Chungyu Chang, A. Bhat, Yi-Wei Chen, Rusul Mohammed Ali, Chenggang Wu, A. Das, Hung Ton-That 2025-05-22 mBio 0 29
visibility_off CoREST in pieces: Dismantling the CoREST complex for cancer therapy and beyond Houssam Ismail, J. Chagraoui, Guy Sauvageau 2025-06-06 Science Advances 0 26
visibility_off PARP Inhibitors in Genitourinary Cancer: A New Paradigm Beyond Prostate Cancer. Yohei Okuda, Taigo Kato, Y. Ishizuya, Takuji Hayashi, Y. Yamamoto, K. Hatano, A. Kawashima, Junko Murai, Norio Nonomura 2025-06-09 International journal of urology : official journal of the Japanese Urological Association 0 29
visibility_off p63 and ZNF148 cooperate to regulate head and neck squamous cell carcinoma. R. Pecorari, Mara Mancini, Artem Smirnov, Giacomo Corleone, Flavia Novelli, A. Lena, Mariacristina Franzese Canonico, M. Montanaro, A. Cappello, A. Sacconi, Gabriella Misso, Michela Falco, Chiara Tammaro, F. Ciccosanti, Mauro Piacentini, M. Scimeca, M. Caraglia, G. Blandino, A. Mauriello, Maurizio Fanciulli, G. Melino, E. Candi 2025-07-15 Proceedings of the National Academy of Sciences of the United States of America 0 61
visibility_off Co-option of an endogenous retrovirus (LTR7-HERVH) in early human embryogenesis: becoming useful and going unnoticed Z. Izsvák, Jin Ma, Manvendra Singh, Laurence D. Hurst 2025-07-05 Mobile DNA 0 61
visibility_off Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG I. Mersich, Sunny Congrove, Matthew Horchar, Roman Caceres, Ranjithmenon Muraleedharan, Janki M Desai, Pankaj B Desai, Larry Sallans, J. Reisz, Abby Grier, Matthew R. Hass, Omer Donmez, Cailing Yin, M. Weirauch, Leah C. Kottyan, Charles B. Stevenson, Claire X. Sun, P. D. de Blank, N. Pillay-Smiley, T. Hummel, N. Elumalai, Ali Tavassoli, Ron Firestein, T. Phoenix, A. D'alessandro, Biplab Dasgupta 2025-05-24 bioRxiv 0 60
visibility_off Evolutionary Transcriptomics of Cancer Development Roman Ivanov, D. Afonnikov, Yury Matushkin, S. Lashin 2025-05-23 International Journal of Molecular Sciences 0 10
visibility_off Abstract P4-12-25: TARGETING BRCA-DEFICIENT CANCER CELLS WITH SMALL MOLECULE RAD52 INHIBITORS Shiva Ostadrahimi, Matthew Rossi, Sarah DiDomenico, Saiful Amin, Alexander Mazin 2025-06-13 Clinical Cancer Research 0 0
visibility_off Multiple highly methylated CpG sites as potential epigenetic markers for the diagnosis of prostate cancer J. Roperch, Guillaume Charbonnier, S. Figiel, Alastair D. Lamb, Ian Mills, Claude Hennion, G. Cancel-Tassin, Olivier Cussenot 2025-07-11 Clinical Epigenetics 0 44
visibility_off piRNA-Mediated Maintenance of Genome Stability in Gametogenesis and Cancer Martyna Zawalska, Maciej Tarnowski 2025-06-20 Genes 0 4
visibility_off Macroscopic Analyses of RNA-Seq Data to Reveal Chromatin Modifications in Aging and Disease Achal Mahajan, Francesca Ratti, Ban Wang, Hana El-Samad, James H. Kaufman, Vishrawas Gopalakrishnan 2025-05-18 bioRxiv 0 11
visibility_off Preparation of topoisomers of short circular dsDNA with defined linking number by accurate topological control Mengqin Liu, Ziyi Wang, Ran An, Angda Li, Xingguo Liang 2025-05-22 Nucleic Acids Research 0 10
visibility_off Nuclear cholesterol regulates nuclear size and DNA damage responses in cancer stem cells. Tingting Duan, S. Taori, S. Bhargava, Sisi Lai, Cuiqing Zhong, Shira Yomtoubian, Huairui Yuan, Xujia Wu, Po Zhang, Tengfei Huang, Donghai Wang, Fanen Yuan, Daqi Li, Huan Li, Hailong Mi, Weichi Wu, Rui Wang, Ahmed Habib, Farrukh Hammed, F. Vendetti, Pascal O. Zinn, Christopher J. Bakkenist, Marlies Meisel, Qiulian Wu, Jeremy N. Rich 2025-06-07 Neuro-oncology 0 16
visibility_off NSUN6 expression correlates with prognosis and immune infiltration in human cancers based on pan-cancer analysis Jie Gao, Yao Xu, Chan Tian, Qiuhong Zhang, Ming Zhang, H. Shan, Jie Shi, Zongjuan Ming, Shuanying Yang, Xia Yang 2025-07-10 Scientific Reports 0 17
visibility_off Chromosome X Open Reading Frame 38 (CXorf38) Is a Tumor Suppressor and Potential Prognostic Biomarker in Lung Adenocarcinoma: The First Characterization Rui Yan, H. Tan, Na-Li Cai, Le Yu, Yan Gao, Yan-Ming Xu, Andy T. Y. Lau 2025-06-01 Proteomes 0 26
visibility_off NUSAP1 regulates mitotic processes via KIF2C interaction and AURKA phosphorylation in primary microcephaly Decheng Ren, Keyi Li, Zhen Liu, Yan Bi, Liangjie Liu, Lei Ji, Ke Yang, Yingying Luo, Le Luo, Yang Yan, Yang Li, Feng-ping Yang, Hua Wang, Guang He, Xiao Mao 2025-05-16 bioRxiv 0 14
visibility_off Abstract P3-04-06: Genomic and transcriptomic profiling of BRCA mutation carrier tissues reveals the landscape of early pathogenesis of BRCA1/2-associated breast cancer Zuen Ren, S. Koh, Kai Stewart, Nick Haradhvala, Aylin S. Dedeoglu, Isabella Vianna, Ilze Smidt, Akiko Suzuki, Taisha Joseph, V. Bossuyt, Esther Rheinbay, Michael Lawrence, Gad Getz, Leif W Ellisen 2025-06-13 Clinical Cancer Research 0 22
visibility_off Epithelial state-transitions permit inflammation-induced tumorigenesis E. Jarman, Anabel Martinez Lyons, Yuelin Yao, Aleksandra Rozyczko, S. Waddell, Andreea Gradinaru, Paula Olaizola, Kyle Davies, Rachel V. Guest, Stephanie Röessler, Timothy J. Kendall, Owen J Sansom, A. Khamseh, Luke Boulter 2025-06-27 bioRxiv 0 9
visibility_off TMPO-AS1-hsa-let-7b-5p-EZH2-RNA network predicts poor survival in basal-like breast cancer patients Prerna Vats, Bhavika Baweja, Sakshi Nirmal, Aditi Singh, Rajeev Nema 2025-06-07 Reports of Practical Oncology and Radiotherapy 0 13
visibility_off Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer M. Volkmar, Dana Hoser, Claudia Lauenstein, Janina Rebmann, Agnes Hotz-Wagenblatt, Jan Rieger, I. Poschke, Jonas P. Becker, Angelika B. Riemer, M. Sprick, A. Trumpp, Oliver Strobel, Thomas Blankenstein, G. Willimsky, R. Offringa 2025-06-01 Journal for Immunotherapy of Cancer 0 39
visibility_off Hypomorphic Lig4 gene mutation in mice predisposes to Th1-skewing intestinal inflammation Yusuke Yamashita, Hideki Kosako, Takashi Kato, I. Sasaki, Sadahiro Iwabuchi, Tadashi Okamura, Misato Tane, Shotaro Tabata, Kazutaka Nakashima, Ken Tanaka, Kazunori Shiraishi, Yuki Uchihara, Daisuke Okuzaki, Atsushi Shibata, Tsunehiro Mizushima, Hiroaki Hemmi, Nobuo Kanazawa, Seiji Kodama, Kouichi Ohshima, Shinichi Hashimoto, Yoshio Fujitani, T. Sonoki, S. Tamura, T. Kaisho 2025-05-17 bioRxiv 0 82
visibility_off Parallel and convergent dynamics in the evolution of primary breast and lung adenocarcinomas Robert A. Gatenby, Jamie K Teer, Kenneth Y. Tsai, Joel S. Brown 2025-05-21 Communications Biology 0 4
visibility_off The cancer fusionome and overexpressed druggable oncogenic signals in K-RAS wild-type pancreatic cancer. Michal Krawczyk, Roisin Puentes, Nathan D Montgomery, Derek D Lyle, R. Kurzrock, F. Lopez-Diaz 2025-06-01 Journal of Clinical Oncology 0 4
visibility_off Decoding the Transcriptional Complexity of the Human BRCA2 DNA Repair Gene Using Hybrid-seq. P. Adamopoulos, Michaela A. Boti, Konstantina Athanasopoulou, P. Tsiakanikas, Glykeria N. Daneva, Andreas Scorilas 2025-07-10 Biochemical genetics 0 16
visibility_off Regulatory Genetic Networks by microRNAs: Exploring Genomic Signatures in Cervical Cancer C. Pérez-Plasencia, Y. C. Orbe-Orihuela, Armando Méndez-Herrera, Jessica Deas, Claudia Gómez-Cerón, H. Jiménez-Wences, J. Ortiz-Ortiz, G. Fernández-Tilapa, Aldo F. Clemente-Soto, J. R. Parra-Unda, J. S. Velarde-Félix, M. Rodríguez-Dorantes, O. Peralta-Zaragoza 2025-06-01 Biomedicines 0 33
visibility_off Efficacy of DNA Methyltransferase Inhibitor Immune Priming Therapy in Combination with PD-1 Inhibitors to Treat High-Risk Pediatric Brain Tumors Deepak Mishra, Shelli M. Morris, Dean Popovski, Emily J. Girard, Andrew Bondoc, S. Kumar, Augusto Faria Andrade, Xiaoting Zhu, Fupan Yao, M. Brusniak, Umaru Banlanjo, Erin E. Crotty, Ken Brasel, Fiona Pakiam, Caterina Russo, M. Zeinieh, Matt C. Biery, Margo Coxon, Heather Conti, Midori Clarke, Mei Lu, James T Rutka, Dhana Llivichuzhca-Loja, Liza Konnikova, M. Fouladi, Nada Jabado, Annie Huang, Jim Olson, R. Drissi 2025-05-18 bioRxiv 0 70
visibility_off Cervical cancer and XRCC1 gene polymorphisms Andréia Michelle Alves Cunha de Alcântara, Ivan Barbosa Barros, Israel Santos da Silva, Karla Roberta Lemos Maul de Souza, Ivan Barbosa Barros, M. Maia, Paulo Roberto Eleutério de Souza 2025-05-30 Revista Eletrônica Acervo Saúde 0 9
visibility_off Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Helen Qian, Heba Ali, Vivekanudeep Karri, Justin T. Low, David M Ashley, Amy B. Heimberger, Lucy A. Godley, A. Sonabend, C. Dmello 2025-06-10 Oncotarget 0 42
visibility_off Abstract P3-04-17: 16q is a breast cancer suppressor arm Sean E Egan, Idil Eda Temel, Yeji An, Katelyn J Kozma, Amanda J. Loch, Wei Wang 2025-06-13 Clinical Cancer Research 0 8
visibility_off Tripartite motif 47 promotes the development of thyroid carcinoma through ADAR ubiquitination Hongzhou Liu, Xiaodong Hu, Tan Li, Yuhan Wang, Xiaomin Fu 2025-07-05 Molecular Medicine 0 8
visibility_off TET3 facilitates bladder cancer progression through targeted modulation of stemness pathways. Zhiren Cai, Yanqi Xie, Luyao Li, Yuhang Zheng, Xianghui Zhou, Guanghua Zhou, Ganping Wang, Xin Zeng 2025-06-26 Medical oncology 0 2
visibility_off Abstract P1-09-18: Activation of HERV-R is a biomarker of poor prognosis among rural Nigerian women with triple-negative breast cancer Faruk Mohammed, Mohammed Daniyan, Ines Hosni, H. S. Musa, S. K. Owolabi, A. Umar, Y. Iliyasu, Rebecca Garnham, Jane Carr-Wilkinson, Sani Ibrahim, Kevin Petrie 2025-06-13 Clinical Cancer Research 0 11
visibility_off Bioinformatic RNA-Seq Functional Profiling of the Tumor Suppressor Gene OPCML in Ovarian Cancers: The Multifunctional, Pleiotropic Impacts of Having Three Ig Domains Adam G. Marsh, Franziska Görtler, S. Hafizi, Hani Gabra 2025-05-29 Current Issues in Molecular Biology 0 28
visibility_off Bioelectric and Epigenetic Landscapes in Lateralized Breast Tumors Reveal Distinct Tumor Microenvironment Signatures Sebastián Real, Sergio R. Laurito, Pablo Gonzalez, Oscar Bello, Joao Carvalho, María Roqué 2025-07-04 bioRxiv 0 8
visibility_off The penetrant chordoid glioma PRKCA mutation is an oncogenic gain-of-function kinase inactivation eliciting early onset chondrosarcoma in mice V. Calleja, Jack C Henry, Mathias Cobbaut, Joanne Sewell, Karine Rizzoti, Francesca Houghton, Stefan Boeing, Nneka Anyanwu, Sunita Varsani-Brown, Thomas Snoeks, A. Suárez-Bonnet, S. Priestnall, N. Q. McDonald, A. Cameron, Peter J. Parker 2025-05-29 bioRxiv 0 26
visibility_off The role and therapeutic value of NUSAP1 in human cancers Shenyuan Xu, Ding Nan, Ruiqi Liu, Chenting Liu, Yuefeng Hu, Luanluan Huang, Xiaoyan Chen, Hailong Sheng, Yanwei Lu, Haibo Zhang 2025-07-02 Journal of Translational Medicine 0 10
visibility_off YTHDFs as radiotherapy checkpoints in tumor immunity. Chuangyu Wen, Emile Z Naccasha, Chuan He, H. Liang, R. Weichselbaum 2025-06-05 The Journal of experimental medicine 0 25
visibility_off Notch3 regulates pericyte phenotypic plasticity in colorectal cancer N. Chalkidi, Athanasia Stavropoulou, V. Arvaniti, Christina Paraskeva, Artemis Monogyiou, Maria Sakkou, Christoforos Nikolaou, V. Koliaraki 2025-06-07 bioRxiv 0 19
visibility_off PIK3R1 and G0S2 are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation Dagne Daskeviciute, Becky Sainty, Louise Chappell-Maor, Caitlin Bone, Sarah Russell, Isabel Iglesias-Platas, Philippe Arnaud, Ana Monteagudo-Sánchez, Maxim V. C. Greenberg, Keran Chen, Africa Manerao-Azua, G. Perez de Nanclares, Jon Lartey, David Monk 2025-06-26 Epigenetics 0 25
visibility_off EHMT1 mediates cellular motility in embryonal rhabdomyosarcoma by activating SOX8 expression. Upasana Bajaj, Dipanwita Das, Jia Yu Leung, Nurul Fateha Binti Abdul Rashi, R. Taneja 2025-06-04 British journal of cancer 0 40
visibility_off Cellular imbalance of specific RNA-binding proteins associates with harmful R-loops José Antonio Mérida-Cerro, Guillaume Chevreux, Benoît Palancade, Ana G. Rondón, A. Aguilera 2025-07-01 PLOS Genetics 0 23
visibility_off Anapc5 and Anapc7 as genetic modifiers of KIF18A function in fertility and mitotic progression Carleigh Nesbit, Whitney Martin, A. Czechanski, Candice Byers, Narayanan Raghupathy, Ardian Ferraj, Jason K. Stumpff, L. Reinholdt 2025-07-02 Scientific Reports 0 32
visibility_off Mitigating Cell Cycle Effects in Multi-Omics Data: Solutions and Analytical Frameworks. Rui Nie, Caihong Zheng, Likun Ren, Yue Teng, Yaoyu Sun, Lifei Wang, Junya Li, Jun Cai 2025-05-28 Advanced science 0 3
visibility_off Investigation of mRNA expression levels of DNA damage response genes in Merkel Cell Polyomavirus-positive Merkel Cell Carcinoma: a pilot study S. Passerini, M. Fracella, A. Ferlosio, U. Moens, C. Scagnolari, Guido Antonelli, Marco Ciotti, V. Pietropaolo 2025-05-21 Discover Oncology 0 44
visibility_off Pituitary tumor transforming gene 1 and endocrine cancers: an up-to-date review through history, current insights and future perspectives. E. Vergani, Emanuela Teveroni, Francesca Mancini, F. Di Nicuolo, S. Raia, S. Chiloiro, F. Pierconti, Antonio Bianchi, A. M. Isidori, Alfredo Pontecorvi, Domenico Milardi 2025-06-01 Endocrine-related cancer 0 25
visibility_off FoxM1 inhibition by Thiostrepton downregulates DNA damage response genes, enhancing sensitivity of breast cancer cells to therapy F. Demırtaş Korkmaz, Zekeriya Düzgün, Fadime Mutlu İçduygu 2025-06-10 Ege Tıp Dergisi 0 5
visibility_off Tumor aneuploidy as a prognostic and predictive biomarker in immune checkpoint blockade. Daniel Huang, L. F. Spurr, R. Weichselbaum, S. Pitroda 2025-06-30 Nature genetics 0 34
visibility_off Circulating tumor DNA in cholangiocarcinoma: current clinical applications and future perspectives Yi Wang, Yike Li, Zhong Liang, Yuqiao Zhang, Tong Li, Chenjun Tian, Jinyu Zhao, Boru Jin, Jie Cao, Yanyan Lin 2025-07-02 Frontiers in Cell and Developmental Biology 0 1
visibility_off High-fidelity long-read sequencing reveals a complex RCCX locus at the single-nucleotide level in Korean patients with congenital adrenal hyperplasia , , D. Kim, S. Park, G.-H. Kim,, , J.-H. Choi,, J. Kim, J. Kim 2025-07-11 None 0 1
visibility_off Substrate heterogeneity promotes cancer cell dissemination Zuzana Dunajova, Saren Tasciyan, Juraj Májek, J. Merrin, E. Sahai, M. Sixt, É. Hannezo 2025-05-23 bioRxiv 0 58
visibility_off P-242 From Cell Division to Clinical Decisions: Unveiling the True Prevalence of Mitotic-Origin Aneuploidies in Preimplantation Embryos M. J. Gomez Cuesta, D. Marin Chavarria, M. I. Gutierrez Estrada, M. Garcia Galicia, G. D. Cortes Ruiz, M. Alonso de Mendieta, C. Kandel Varsano, C. Lopez Valencia, E. Cervantes Bravo 2025-06-01 Human Reproduction 0 0
visibility_off Monitoring the rate and variability of somatic genomic alterations using long-read sequencing Xingyao Chen, Hagai Ligumsky, Charlie Ambrose, Denisse Sibrian, Brian Tran, Daoud Arif, Olga Castellanos, Darren Kessner, Hanyi Luo, Mukta Ubale, Abigail Coleman, Vaidhyanathan Mahaganapathy, Thomas J Jönsson, R. Basho, Jerry S H Lee, Naim Matasci, David B. Agus 2025-06-11 Scientific Reports 0 13
visibility_off Characterizing clinical outcomes and DNA co-alterations of ERBB2-amplified colorectal cancer. Mohamed Nuh, Monica Hsiang, Sunyoung S. Lee 2025-06-01 Journal of Clinical Oncology 0 3
visibility_off Clinical Significance of TERT Promoter Mutations in Neuroblastoma. Natasha Persaud, G. Gundem, B. Kushner, Marc Ladanyi, Neerav Shukla, S. Modak 2025-07-01 JCO precision oncology 0 45
visibility_off Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB Bertha Osei, Benjamin H. May, Joseph S Beard, Matthew D Thompson, Duah Alkam, M. Zafar, Erik Bergstrom, Stephanie D. Byrum, Eric J Enemark, Kirk L. West, Alicia K. Byrd 2025-04-01 Nar Molecular Medicine 0 24
visibility_off A comprehensive, multi-center, immunogenomic analysis of melanoma brain metastases L. B. Kennedy, Amanda E. D. Van Swearingen, Marissa R Lee, Layne W. Rogers, A. Sibley, Jeff Sheng, Dadong Zhang, Xiaodi Qin, E.S. Lipp, Swaminathan Kumar, Aron Y Joon, Pixu Shi, Michael A. Davies, K. Owzar, Carey K. Anders, April K S Salama 2025-06-02 Acta Neuropathologica Communications 0 18
visibility_off M6Allele: a toolkit for detection of allele-specific RNA N6-methyladenosine modifications Yin Zhang, Lin Tang, Shengyao Zhi, Bosu Hu, Zhixiang Zuo, Jian Ren, Yubin Xie, Xiaotong Luo 2025-01-06 GigaScience 0 13
visibility_off ITX-0121: A therapeutic strategy for transcription-coupled repair-deficient cancers. M. Kelner, Raymond T. Suhandynata, Venkata R. Kotamraju 2025-06-01 Journal of Clinical Oncology 0 3
visibility_off The Multifaceted Roles of CHROMR in Innate Immunity, Cancer, and Cholesterol Homeostasis Emma R. Blaustein, Coen van Solingen 2025-06-01 Non-Coding RNA 0 15
visibility_off Nonequilibrium polysome dynamics promote chromosome segregation and its coupling to cell growth in Escherichia coli Alexandros Papagiannakis, Qiwei Yu, Sander K. Govers, Wei-Hsiang Lin, N. Wingreen, C. Jacobs-Wagner 2025-06-24 eLife 0 79
visibility_off Transcriptomic Analyses of Ovarian Clear Cell Carcinoma Spheroids Reveal Distinct Proliferative Phenotypes and Therapeutic Vulnerabilities Bartlomiej Kolendowski, Sylvia Cheng, Yudith Ramos Valdés, Trevor G. Shepherd, G. DiMattia 2025-05-27 Cells 0 34
visibility_off A continuum reaction-diffusion model for spread of gene silencing in chromosomal inactivation Shibashis Paul, Sha Sun, Karmella A. Haynes, Tian Hong 2025-06-04 bioRxiv 0 2
visibility_off Molecular characterization of STEAP1 and -2 in advanced prostate cancer. Kevin K. Zarrabi, T. Adeyelu, A. Elliott, D. Geynisman, D. Oh, Carissa E. Chu, Rana R McKay, Nicholas A Zorko, E. Antonarakis, Lucia R Languino, Pedro C. Barata, D. Danila, Norm Smith, William Kevin Kelly 2025-06-01 Journal of Clinical Oncology 0 42
visibility_off Divergent FOXA1 mutations drive prostate tumorigenesis and therapy-resistant cellular plasticity. Sanjana Eyunni, R. Mannan, Yuping Zhang, E. Young, Qiuyang Zhang, Jie Luo, Matthew Pang, Somnath Mahapatra, J. Tien, James M. George, Mustapha Jaber, Hamzah Hakkani, Sandra E Carson, Abigail J Todd, Noshad Hosseini, M. Gondal, Ryan J. Rebernick, Xuhong Cao, Fengyun Su, Rui Wang, Rohit Mehra, Jing Li, Marcin P. Cieslik, A. Chinnaiyan, A. Parolia 2025-06-26 Science 0 169
visibility_off Methylated ARHGAP40 DNA as a potential biomarker for early diagnosis in high-grade ovarian serous cancer Jiaxin Chai, Dongni Leng, Shuwei Guo, Rusong Zhang, Jiandong Wang, Yun Gu, Qiu Rao 2025-07-02 Journal of Ovarian Research 0 1
visibility_off Structure, Function and Clinical Significance of P53 Protein: A Review Article Farah mumtaz, Hadeel Nasser, Ruqaya Yahya Abd AL-Shaheed, Ali A. Al-fahham 2025-05-28 International Journal of Health & Medical Research 0 4
visibility_off BRCA2 reversion mutation–independent resistance to PARP inhibition through impaired DNA prereplication complex function Kyrie Pappas, Matteo Ferrari, Perianne Smith, S. Nandakumar, Zahra Khan, Serina B. Young, Justin Laclair, M. V. Russo, Emmet Huang-Hobbs, Nikolaus Schultz, W. Abida, Wouter Karthaus, M. Jasin, Charles L Sawyers 2025-06-03 Proceedings of the National Academy of Sciences of the United States of America 0 100
visibility_off Replaying germinal center evolution on a quantified affinity landscape William S DeWitt, Ashni A. Vora, Tatsuya Araki, Jared G. Galloway, T. Alkutkar, Juliana Bortolatto, Tiago B.R. Castro, Will Dumm, Chris Jennings-Shaffer, Tongqiu Jia, L. Mesin, G. Ozorowski, Juhee Pae, Duncan K. Ralph, Jesse D. Bloom, Armita Nourmohammad, Yun S. Song, A. Ward, Tyler N. Starr, Frederick A. Matsen, G. Victora 2025-06-05 bioRxiv 1 45
visibility_off Identification of novel genetic mutations for the treatment prognostication of canine lymphoma Josephine Tsang, Qi-Jing Yap, Sheena Kapoor, Jerry Cromarty, Sushmita Sen, Minji Kim, George Courcoubetis, Suhyeon Cho, Deanna Swartzfager, Stanley Park, Sungwon Lim, Ilona Holcomb, Jamin Koo 2025-06-12 NPJ Precision Oncology 0 6
visibility_off Exploring genetic and epigenetic alterations in hTERT gene in colorectal cancer Meryem Jafari, Boutaina Addoum, A. Laraqui, Mohammed Oukabli, Ahmed Bounaim, Abdelmounim Ait Ali, Sidi Mohammed Bouchantouf, Noureddine Njoumi, Belkouchi Abdelkader, Fatima Zohra BenMoula, Hicham El Annaz, Khalid Ennibi, I. Chaoui, Youssef Bakri, Mohammed Attaleb 2025-06-03 Eurasian Journal of Medicine and Oncology 0 19
visibility_off Loss of chromosome Y shapes the immune cell fate with aging in men A. A. Z. Dawoud, L. Green, O. Rackham 2025-06-02 None 0 0
visibility_off Structural basis of Fanconi anemia pathway activation by FANCM. R. Bythell-Douglas, Sylvie van Twest, Lara Abbouche, Elyse Dunn, Rachel J Coulthard, D. Briggs, Vincent J. Murphy, Xinxin Zhang, Winnie Tan, Sarah S Henrikus, Dongming Qian, Yin Wu, Jana Wolf, Laurent Rigoreau, S. Shakeel, Kathryn L Chapman, N. Q. McDonald, A. Deans 2025-05-30 The EMBO journal 0 24
visibility_off RNA G-quadruplexes: emerging regulators of gene expression and therapeutic targets. Zukela Ruzi, Wei Zha, Huang Yuan Yuan, Jiaorui Liu 2025-07-03 Functional & integrative genomics 0 5
visibility_off Stratification of Hepatocellular Carcinoma Using N6-Methyladenosine Nan Wang, Jia-Xin Shi, M. Bartneck, E. Dahl, Junqing Wang 2025-07-01 Cancers 0 3
visibility_off Chinmo defines the region-specific oncogenic competence in the Drosophila central nervous system Phuong-Khanh Nguyen, Francesca Froldi, Louise Y. Cheng 2025-05-21 bioRxiv 0 14
visibility_off Effect of elevated expression of LILRB4 and TSC22D3 on survival in lung cancer. B. Hrinczenko, T. Adeyelu, Wei-Zen Wei, A. Elliott, G. Bepler, A. Vanderwalde, B. Halmos, E. Antonarakis, Maryam B Lustberg, Jennifer Jacob 2025-06-01 Journal of Clinical Oncology 0 60
visibility_off Total m6A RNA levels and VIRMA expression as potential diagnostic and prognostic markers in oral squamous cell carcinoma Kaori Shima, Yudai Shimojukkoku, Yasunobu Oku, Kanako Higashimoto, Takahiro Tsuchiyama, Yuka Kajiya, Miyako Kurihara-Shimomura, Tomonori Sasahira 2025-07-03 Diagnostic Pathology 0 10
visibility_off MCT1-mediated histone lactylation modulates lung cancer cell sensitivity to T-cell–mediated killing by influencing mitochondrial dysfunction. Q. Xue, W. Peng, Qiong Zhou 2025-06-01 Journal of Clinical Oncology 0 10
visibility_off Abstract P2-11-03: Quantification of Breast Cancer 1 gene (BRCA1) promoter methylation in individuals with and without cancer using cell-free DNA F. Menghi, Margaret Antonio, William Cance, Tracy Nance, Edison T. Liu 2025-06-13 Clinical Cancer Research 0 17
visibility_off CRISPR-Cas induced self-targeting identifies key players in archaeal microhomology mediated end joining A-L. Sailer, J. Wörtz, V. Smith, A. Stachler, F. Blau, M. Daratha, L-K Maier, T. Allers, A. Marchfelder 2025-07-08 microLife 0 37
visibility_off Oncogenic role of fumarate hydratase in breast cancer: metabolic reprogramming and mechanistic insights Shyng-Shiou F Yuan, Anupama Vadhan, Hieu D. H. Nguyen, Pang-Yu Chen, Chih-Huang Tseng, Ching-Hu Wu, Yu-Chieh Chen, Yi-Chia Wu, Stephen Chu‐Sung Hu, S. Lo, Ming-Feng Hou, Yen-Yun Wang 2025-05-29 Cancer & Metabolism 0 16
visibility_off Elimination of Carryover Contamination during Nucleic Acid Amplification Based on Damaged Base Excision by DNA Repair Enzymes. Xiaonan Liu, Wenjing Hu, Huyun Zhou, Jiaxing Zhang, Mengyang Zhao, Yali Cui, Jiangwei Yan 2025-06-03 Analytical chemistry 0 12
visibility_off Genomic Subclassification and Risk Stratification of ALL. Anna Østergaard, Ilaria Iacobucci 2025-06-30 Acta haematologica 0 0
visibility_off SCLC-TumorMiner: A Directly Accessible Genomics Resource for Precision Oncology – Big Data for Small Cells Fathi Elloumi, A. Dhall, Daiki Taniyama, Augustin Luna, Yasuhiro Arakawa, Sudhir Varma, Jeffrey Wang, Anisha Tehim, Mark Raffeld, Kenneth Aldape, Christophe E. Redon, Roshan Shresta, William C Reinhold, M. Aladjem, Jaydira Del Rivero, Nitin Roper, Anish Thomas, Y. Pommier 2025-07-10 bioRxiv 0 48
visibility_off TIGAR regulated by HPV E6 is correlated with disease stage, drug sensitivity, and immune microenvironment in cervical cancer Yameng Liu, Yu Zhang, Hailong Zhang, Dianqin Xu, Xinzhu Zhou, Luhong Xie, Hongli Xi, Yurong Zhu, Hanlin Yang, Xiaoyu Zhu, Ji Ren, Shaoju Min, Yujie Tan 2025-07-01 Scientific Reports 0 6
visibility_off How the chromatin landscape influences nuclear morphology Sourabh Sengupta, Haritha Prabha, Daniel L. Levy 2025-07-03 Frontiers in Cell and Developmental Biology 0 1
visibility_off Post-translational modifications in DNA damage repair: mechanisms underlying temozolomide resistance in glioblastoma. Yike Chen, Kaikai Ding, Shuyu Zheng, Songting Gao, Xiaohui Xu, Haijian Wu, Fengqi Zhou, Yongjie Wang, Jinfang Xu, Chun Wang, C. Ling, Jing Xu, Lin Wang, Qun Wu, G. Giamas, Gao Chen, Jianmin Zhang, Chenggang Yi, Jianxiong Ji 2025-05-26 Oncogene 0 32
visibility_off Biallelic loss-of-function variants in ZNF142 are associated with a robust DNA methylation signature affecting a limited number of genomic loci. Mathis Hildonen, A. Ciolfi, Marco Ferilli, Camilla Cappelletti, Chadi Al Alam, David J. Amor, T. S. Barakat, Valérie Benoit, O. S. Birk, B. Callewaert, Ana Cazurro-Gutiérrez, Matthias De Wachter, Martine Doco-Fenzy, P. Gómez-Puertas, T. Hammer, R. Jamra, R. Kaiyrzhanov, Shinichi Kameyama, B. Keren, Christina Kresge, Ilona Krey, Damien Lederer, Í. Marcos-Alcalde, Reza Maroofian, Naomichi Matsumoto, T. Mizuguchi, L. Moey, Angela T. Morgan, Francina Munell, K. Platzer, Beth Pletcher, D. Ros-Pardo, Lynne Rumping, K. Szakszon, K. Van Schil, Edgard Verdura, Julie Vogt, E. Wassmer, Mina Zamani, Z. Tümer, M. Tartaglia 2025-05-23 European journal of human genetics : EJHG 0 47
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visibility_off The Rise of New Targets in Melanoma. Xue Bai, Keith T Flaherty 2025-06-26 The British journal of dermatology 0 2
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